Distinct roles for insulin and insulin-like growth factor-1 receptors in pancreatic β-cell glucose sensing revealed by RNA silencing

Biochemical Journal

Volumn 377, Issue 1, 2004, Pages 149-158

  Da Silva Xavier, Gabriela ^a   Qian, Qingwen ^a   Cullen, Peter J ^a   Rutter, Guy A ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

Diabetes; Glucose; Insulin; Islet cell; Small interfering RNA (siRNA)

Indexed keywords

CLONING; ENZYME KINETICS; GENES; GLUCOSE; GROWTH KINETICS; OXIDATION; RNA;

GENE EXPRESSIONS;

INSULIN;

ADENOSINE TRIPHOSPHATE; GLUCOKINASE; GLUCOSE; INSULIN RECEPTOR; PROINSULIN; SMALL INTERFERING RNA; SOMATOMEDIN C RECEPTOR; TRANSCRIPTION FACTOR PDX 1;

AEROBIC METABOLISM; ARTICLE; CELL LINE; CONCENTRATION RESPONSE; DEPOLARIZATION; GENE EXPRESSION REGULATION; GENE SILENCING; INSULIN RELEASE; MITOCHONDRIAL RESPIRATION; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION;

ADENOSINE TRIPHOSPHATE; ANIMALS; CELL LINE; DIAZOXIDE; GENE EXPRESSION REGULATION; GLUCOKINASE; GLUCOSE; HOMEODOMAIN PROTEINS; INSULIN; MICE; PANCREAS; PROINSULIN; PROTEIN PRECURSORS; RECEPTOR, IGF TYPE 1; RECEPTOR, INSULIN; RNA INTERFERENCE; RNA, MESSENGER; TRANS-ACTIVATORS;

EID: 1642453553     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20031260     Document Type: Article

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