Frequent loss of the AXIN1 locus but absence of AXIN1 gene mutations in adenocarcinomas of the gastro-oesophageal junction with nuclear β-catenin expression

British Journal of Cancer

Volumn 90, Issue 4, 2004, Pages 892-899

  Koppert, L B ^a,b   Van Der Velden, A W ^a   Van De Wetering, M ^c   Abbou, M ^a   Van Den Ouweland, A M W ^b   Tilanus, H W ^b   Wijnhoven, B P L ^b   Dinjens, W N M ^a  

^a JOSEPHINE NEFKENS INSTITUTE   (Netherlands)

^b ERASMUS MEDICAL CENTER   (Netherlands)

^c HUBRECHT INSTITUTE   (Netherlands)

Author keywords

AXIN1; Loss of heterozygosity; Mutation; Oesophageal cancer; Wnt signalling pathway

Indexed keywords

APC PROTEIN; AXIN; AXIN 1; AXIN 2; BETA CATENIN; BETA TRANSDUCIN REPEAT CONTAINING PROTEIN; T CELL FACTOR PROTEIN; TRANSDUCIN; UNCLASSIFIED DRUG; WNT PROTEIN; AXIN PROTEIN; CADHERIN; CTNNB1 PROTEIN, HUMAN; CYTOSKELETON PROTEIN; ONCOPROTEIN; PROTEIN TYROSINE KINASE; REPRESSOR PROTEIN; TRANSACTIVATOR PROTEIN; ZEBRAFISH PROTEIN;

ADENOCARCINOMA; ARTICLE; CELL ADHESION; CELL NUCLEUS; COLON POLYPOSIS; CONTROLLED STUDY; ESOPHAGUS CANCER; EXON; GENE DOSAGE; GENE EXPRESSION; GENE MUTATION; HETEROZYGOSITY LOSS; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REPORTER GENE; SINGLE NUCLEOTIDE POLYMORPHISM; SINGLE STRAND CONFORMATION POLYMORPHISM; BIOSYNTHESIS; CELL CULTURE; ESOPHAGUS TUMOR; GENETICS; PATHOPHYSIOLOGY; SIGNAL TRANSDUCTION; STOMACH TUMOR;

ADENOCARCINOMA; BETA CATENIN; CADHERINS; CYTOSKELETAL PROTEINS; DNA MUTATIONAL ANALYSIS; ESOPHAGEAL NEOPLASMS; GENE DOSAGE; HUMANS; IMMUNOHISTOCHEMISTRY; LOSS OF HETEROZYGOSITY; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; STOMACH NEOPLASMS; TRANS-ACTIVATORS; TUMOR CELLS, CULTURED; WNT PROTEINS; ZEBRAFISH PROTEINS;

EID: 1642376572     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6601589     Document Type: Article

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