Apple juice prevents oxidative stress and impaired cognitive performance caused by genetic and dietary deficiencies in mice

Journal of Nutrition, Health and Aging

Volumn 8, Issue 2, 2004, Pages 92-97

  Rogers, E J ^a   Milhalik, S ^a   Ortiz, D ^a   Shea, T B ^a  

^a University of Massachusetts Lowell   (United States)

Author keywords

Antioxidant; Apples; Cognition; Folate; Maze trials; Oxidative stress; TBARs; Vitamin E

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; APOLIPOPROTEIN E; FOLIC ACID; REACTIVE OXYGEN METABOLITE; SUGAR;

AGING; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APPLE JUICE; ARTICLE; BRAIN PROTECTION; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; DIET SUPPLEMENTATION; DIETARY INTAKE; FEMALE; FOOD COMPOSITION; FRUIT; GENETIC DISORDER; MALE; MAZE TEST; MOUSE; NERVE DEGENERATION; NEUROPROTECTION; NONHUMAN; NUTRITIONAL DEFICIENCY; OXIDATIVE STRESS; PRIORITY JOURNAL; TASK PERFORMANCE; TRANSGENIC MOUSE; VEGETABLE;

ANIMALIA; MALUS X DOMESTICA; MUS MUSCULUS;

EID: 1642337794     PISSN: 12797707     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (67)

1. Berr C (2002) Oxidative stress and cognitive impairment in the elderly. J Nutr Health Aging. 6:261-266.
2. Butterfield DA and Lauderback CM (2002) Lipid peroxidation and protein oxidation in Alzheimer's disease: potential causes and consequences involving amyloid-beta peptide-associated free radical oxidative stress. Free Rad Biol Med 32:1050-1060.
3. Floyd RA and Hensley K (2002) Oxidative stress in brain aging. Implications for therapeutics of neurodegenerative diseases. Neurobiol Aging. 23:795-807.
4. Perry G, Cash AD, Smith MA (2002a) Alzheimer Disease and Oxidative Stress. J Biomed Biotechnol. 2:120-123.
5. Perry G, Nunomura A, Hirai K, Zhu X, Prez M, Avila J, Castellani RJ, Atwood CS, Aliev G, Sayre LM, Takeda A, Smith MA (2002b) Is oxidative damage the fundamental pathogenic mechanism of Alzheimer's and other neurodegenerative diseases? Free Radic Biol Med. 33:1475-1479.
6. Herrmann N (2002) Cognitive pharmacotherapy of Alzheimer's disease and other dementias. Can J Psychiatry. 47:715-722.
7. Klatte ET, Scharre DW, Nagaraja HN, Davis RA, Beversdorf DQ. (2003) Combination therapy of donepezil and vitamin E in Alzheimer disease. Alzheimer Dis Assoc Disord. 17:113-116.
8. Lalonde R, Joyal CC, Botez MI (1993) Effects of folic acid and folinic acid on cognitive and motor behaviors in 20-month-old rats. Pharmacol Biochem Behav. 44:703-707.
9. Luchsinger JA, Tang MX, Shea S, Mayeux R.(2003) Antioxidant vitamin intake and risk of Alzheimer disease. Arch Neurol. 60:203-208.
10. Martin A (2003) Antioxidant vitamins E and C and risk of Alzheimer's disease. Nutr Rev. 61:69-73.
11. Mattson MM and Shea TB (2002) Folate and Homocysteine in Neural Plasticity and Neurodegenerative Disorders. Trends in Neurosciences 26:137-146.
12. Shea TB and Rogers E (2002a) Homocysteine as a risk factor for Alzheimer's disease. New Eng J Med 346:2007
13. Shea TB, Lyons-Wieler J and Rogers E (2002a) Homocysteine, folate deprivation and Alzheimer's disease. J Alz Dis 4:261-268
14. Eberhardt RT, Forgione MA, Cap A, Leopold JA, Rudd MA, Trolliet M, Heydrick S, Stark R, Klings ES, Moldovan NI, Yaghoubi M, Goldschmidt-Clermont PJ, Farber HW, Cohen R, Loscalzo J (2000) Endothelial dysfunction in a murine model of mild hyperhomocyst(e)inemia. J Clin Invest. 106:483-491.
15. Yamori Y, Horie R. (1994) Community-based prevention of stroke: nutritional improvement in Japan. Health Rep. 6:181-188
16. Cao G, Verden CP, Wu AHB, Wang H, Prior RL (1995) Automated oxygen radical absorbance capacity assay using the COBAS FARA II. Clin Chem 41:1738-1744.
17. Cao G, Sofic E, Prior RL (1996) Antioxidant capacity of tea and common vegetables. J Agric Food Chem 44:3426-3431.
18. Meydani SN, Wu D, Santos MS, Hayek MG (1995) Antioxidants and immune response in aged persons: overview of present evidence. Am J Clin Nutr 62:1462S-1476S.
19. Sun YX, Minthon L, Wallmark A, Warkentin S, Blennow K, Janciauskiene S. (2003) Inflammatory markers in matched plasma and cerebrospinal fluid from patients with Alzheimer's disease. Dement Geriatr Cogn Disord. 16:136-144.
20. Taylor A, Nowell T (1997) Oxidative stress and antioxidant function in relation to risk for cataract. Adv Pharmacol. 1997
21. Ortiz D and Shea TB (2003) Apple juice prevents oxidative stress induced by amyloid-beta in culture. J Alz Dis: in press.
22. Willett WC (1986) Selenium, vitamin E, fiber, and the incidence of human cancer: an epidemiologic perspective. Adv Exp Med Biol. 1986
23. Hughes K (1995) Diet and coronary heart disease: a review. Ann Acad Med Singapore 24:224-229.
24. Mayne ST (1996) Beta-carotene, carotenoids and disease prevention in humans. FASEB J 10:690-701.
25. Rai SS, Shovlin C, Wesnes KA (1991) A double-blind placebo controlled study of Ginkgo biloba extract ("tanakan") in elderly outpatients with mild to moderate memory impairment. Curr Med Res Opin 12:350-355.
26. Kleijnen J, Knipschild P (1992a) Ginkgo biloba. Lancet 340:1136-1139.
27. Kleijnen J, Knipschild P (1992b) Ginkgo biloba for cerebral insufficiency. Br J Clin Pharmacol 34:352-358.
28. Kanowski S, Herrmann WM, Stephan K, Wierich W, Horr R (1996) Proof of efficacy of the ginkgo biloba special extract EGb 761 in outpatients suffering from mild to moderate primary degenerative dementia of the Alzheimer type or multi-infarct dementia. Pharma-copsychiatry 29:47-56.
29. Joseph JA, Shukitt-Hale B, Denisova NA, Prior RL, Cao G, Martin A, Taglialatela G, and Bickford PC (1998) Long-Term Dietary Strawberry, Spinach, or Vitamin E Supplementation Retards the Onset of Age-Related Neuronal Signal-Transduction and Cognitive Behavioral Deficits J. Neurosci. 18:8047-8055.
30. Smith MA, Petot GJ, Perry G.(1999) Diet and Oxidative Stress: A Novel Synthesis of Epidemiological Data on Alzheimer's Disease. J Alzheimers Dis. 1999 Nov; 1(4,5):203-206.
31. Joseph JA, Shukitt-Hale B, Denisova NA, Prior RL, Cao G, Martin A, Taglialatela G, and Bickford PC (1998) Long-Term Dietary Strawberry, Spinach, or Vitamin E Supplementation Retards the Onset of Age-Related Neuronal Signal-Transduction and Cognitive Behavioral Deficits J. Neurosci. 18:8047-8055.
32. Joseph JA, Shukitt-Hale B, Denisova NA, Bielinski D, Martin A, McEwen JJ, and Bickford PC (1999) Reversals of Age-Related Declines in Neuronal Signal Transduction, Cognitive, and Motor Behavioral Deficits with Blueberry, Spinach, or Strawberry Dietary Supplementation J. Neurosci. 19:8114-8121
33. Growdon J. (2001) Incorporating biomarkers into clinical drug trials in Alzheimer's disease. J Alz Dis 3, 287-292.
34. Ramassamy C., Averill D, Beffert L., Throux L., Lussier-Cacan S., Cohn J.S., Christen Y., Schoofs J. and Davignon J. (1999) Oxidative damage and protection by antioxidants in the frontal cortex of Alzheimer's disease is related to the apolipoprotein E genotype. Free Rad Biol Med 27, 544-553.
35. Huang GS, Yang SM, Hong MY, Yang PC and Liu YC (2000) Differential gene expression of livers from ApoE deficient mice. Life Sci. 68:19-28.
36. Ramassamy C, Averill D, Beffert U, Theroux L, Lussier-Cacan S, Cohn JS, Christen Y, Schoofs A, Davignon J and Poirier J (2000) Oxidative insults are associated with apolipoprotein E genotype in Alzheimer's disease brain. Neurobiol Dis. 2000 Feb;7(1):23-37.
37. Ramassamy C., Krzywkowski P, Averill D, Lussier-Cacan S., Throux L., Christen Y., Sch Davignon J and Poirier J (2002) Impact of apolipoprotein E deficiency on oxidative insults and antioxidant levels in the brain. Mol Brain Res 86:76-83
38. Shea TB, Rogers E, Ortiz D and Sheu M-S (2002b) Apolipoprotein E deficiency promotes increased oxidative stress and compensatory increases in antioxidants in brain fissue. Free Rad Biol Med 33:1115-1120.
39. Shea, TB, Rogers E, Ashline D, Ortiz D, Duarte N, Wilson TA, Nicolosi RJ and Sheu M-H (2002c) Vitamin E deficiency does not induce compensatory antioxidant increases in central nervous system tissue of apolipoprotein E-deficient mice. J Alz Dis 4:1-6.
40. Leontowicz H, Gorinstein S, Lojek A, Leontowicz M, Ciz M, Soliva-Fortuny R, Park YS, Jung ST, Trakhtenberg S, Martin-Belloso O. (2002) Comparative content of some bioactive compounds in apples, peaches and pears and their influence on lipids and antioxidant capacity in rats. J Nutr Biochem. 13:603-610.
41. van der Sluis AA, Dekker M, Verkerk R, Jongen WM. An improved, rapid in vitro method to measure antioxidant activity. Application On selected flavonoids and apple juice. J Agric Food Chem. 2000 Sep;48(9):4116-22.
42. Wolfe KL, Liu RH. (2003) Apple peels as a value-added food ingredient. J Agric Food Chem 51:1676-1683.
43. Wolfe K, Wu X, Liu RH. (2003) Antioxidant activity of apple peels. J Agric Food Chem. 51:609-614.
44. Shea TB and Rogers E (2002b) Folate quenches oxidative damage in brains of apolipoprotein E-deficient mice: augmentation by vitamin E. Mol Brain Res: 108:1-6.
45. Corcoran KA, Lu Y, Turner RS and Maren S (2002). Overexpression of hAPPswe impairs rewarded alternation and contextual fear conditioning in a transgenic mouse model of Alzheimer's disease. Learn Mem 9:243-252.
46. King DL, Arendash GW, Crawford F, Sterk T, Menendez J, Mullan MJ (1999) Progressive and gender-dependent cognifive impairment in the APP(SW) transgenic mouse model for Alzheimer's disease. Behav Brain Res 103:145-162
47. Mihalick SM, Ortiz D, Kumar R, Rogers E and Shea TB (2003) Folate and vitamin E deficiency impair cognitive performance in mice subjected to oxidative stress: differential impact on normal mice and mice lacking apolipoprotein E. Neuromol Med: in press.
48. Matzel LD, Han YR, Grossman H, Kamik MS, Patel D, Scott N, Specht SM, Gandhi CC.(2003) Individual Differences in the Expression of a "General" Leaming Ability in Mice. J Neurosci. 23:6423-6433.
49. Lovell MA, Ehmann WD, Butler SM, Markesbery WR (1995) Elevated thiobarbituric acid-reactive substances and antioxidant enzyme activity in the brain in Alzheimer's disease. Neurol 45:1594-1601.
50. Gordon I, Grauer E, Genis I, Sehayek E, Michaelson DM. (1995) Memory deficits and cholinergic impairments in apolipoprotein E-deficient mice. Neurosci Lett. 1995
51. Gordon I, Genis I, Grauer E, Sehayek E, Michaelson DM. (1996) Biochemical and cognitive studies of apolipoprotein-E-deficient mice. Mol Chem Neuropathol. 1996
52. Masliah E, Armasolo F, Veinbergs I, Mallory M, Samuel W. (1999) Cerebrolysin ameliorates performance deficits, and neuronal damage in apolipoprotein E-deficient mice. Pharmacol Biochem Behav. 62:239-245.
53. Oitzl MS, de Kloet ER, Joels M, Schmid W, Cole TJ. (1997) Spatial leaming deficits in mice with a targeted glucocorticoid receptor gene disruption. Eur J Neurosci. 9:2284-2296.
54. Raber J, Wong D, Yu GQ, Buttini M, Mahley RW, Pitas RE, Mucke L.(2000) Apolipoprotein E and cognitive performance. Nature. 404:352-354.
55. Veinbergs I, Mallory M, Sagara Y and Masliah E (2000) Vitamin E supplementation prevents spatial leaming deficits and dendritic alterations in aged apolipoprotein E-deficient mice. Eur J Neurosci 12:4541-4546
56. Zhou Y, Elkins PD, Howell LA, Ryan DH, Harris RB.(1998) Apolipoprotein-E deficiency results in an altered stress responsiveness in addition to an impaired spatial memory in young mice. Brain Res. 788:151-159.
57. Fukui K, Omoi NO, Hayasaka T, Shinnkai T, Suzuki S, Abe K, Urano S (2002) Cognitive impairment of rats caused by oxidative stress and aging, and its prevention by vitamin E. Ann N Y Acad Sci. 959:275-284
58. Mizrahi EH, Jacobsen DW, Debanne SM, Traore F, Lemer AJ, Friedland RP, Petot GJ. (2003) Plasma Total Homocysteine Levels, Dietary Vitamin B6 and Folate Intake In AD and Healthy Aging. J Nutr Health Aging. 7:160-165.
59. Sarter M, van der Linde A (1987) Vitamin E deprivation in rats: some behavioral and histochemical observations. Neurobiol Aging. 1987
60. Lalonde, R. (2002). The neurobiological basis of spontaneous alternation. Neurosci Biobehav Rev 26:91-104.
61. Douglas, R.J. & Raphaelson, A.C. (1966). Spontaneous alternation and septal lesions. J Comp Physiol Psychol, 62, 320-322.
62. Johnson CT, Olton DS, Gage FH 3rd, Jenko PG. (1997) Damage to hippocampus and hippocampal connections: effects on DRL and spontaneous alternation. J Comp Physiol Psychol. 1977
63. Thomas, J.B. (1972). Stimulus perserveration and choice behavior in rats with septal lesions. J Comp Physiol Psychol, 80, 97-105.
64. Weis, B.J. and Means, L.W. (1980). A comparison of the effects of medial frontal, dorsomedial thalamic, and combination lesions on discrimination and spontaneous alternation in the rat. Physiol Psychol, 8, 325-329.
65. Ramirez, J.J. & Stein, D.G. (1984). Sparing and recovery of spatial alternation performance after entorhinal cortex lesions in rats. Behav Brain Res, 13, 53-61.
66. Butterfield D, Castegna A, Pocemich C, Drake J, Scapagnini G, Calabrese V. (2000) Nutritional approaches to combat oxidative stress in Alzheimer's disease Eur J Neurosci 12:4541-4546
67. Butterfield DA, Castegna A, Lauderback CM and Drake J (2002) Evidence that amyloid beta-peptide-induced lipid peroxidation and its sequelae in Alzheimer's disease brain contribute to neuronal death. Neurobiol Aging. 23:655-664.