Hepatocyte CYP2E1 overexpression and steatohepatitis lead to impaired hepatic insulin signaling

Journal of Biological Chemistry

Volumn 280, Issue 11, 2005, Pages 9887-9894

  Schattenberg, Jörn M ^a   Wang, Yongjun ^a   Singh, Rajat ^a   Rigoli, Raina M ^a   Czaja, Mark J ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL ORGANS; CYTOLOGY; DISEASE CONTROL; FATTY ACIDS; GENETIC ENGINEERING; PHOSPHORS; SIGNALING;

CYTOCHROME; FATTY LIVER DISEASE; HEPATOCYTE OVEREXPRESSION; INSULIN RESISTANCE;

INSULIN;

CHOLINE; CYTOCHROME P450 2E1; GLYCOGEN SYNTHASE KINASE 3; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTOR SUBSTRATE 2; METHIONINE; PROTEIN KINASE B; SERINE; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR FKHR; TYROSINE;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CELL FRACTIONATION; DOWN REGULATION; ENZYME ACTIVATION; IMMUNOPRECIPITATION; IN VITRO STUDY; IN VIVO STUDY; INSULIN METABOLISM; INSULIN RESISTANCE; LIVER CELL; NONALCOHOLIC FATTY LIVER; NONHUMAN; NORTHERN BLOTTING; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SECRETIONS; WESTERN BLOTTING;

ADENOVIRIDAE; ANIMALS; BLOTTING, NORTHERN; BLOTTING, WESTERN; CELL LINE; CHOLINE; CYTOCHROME P-450 CYP2E1; DNA-BINDING PROTEINS; DOWN-REGULATION; FATTY LIVER; FORKHEAD TRANSCRIPTION FACTORS; GLUCOSE; GLUTATHIONE PEROXIDASE; GLYCOGEN SYNTHASE KINASE 3; HEPATITIS; HEPATOCYTES; HUMANS; IMMUNOPRECIPITATION; INSULIN; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE KINASE 4; METHIONINE; MICE; MICE, INBRED C57BL; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; PHOSPHORYLATION; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RNA; SERINE; SIGNAL TRANSDUCTION; SUBCELLULAR FRACTIONS; TIME FACTORS; TRANSCRIPTION FACTORS; TYROSINE; UP-REGULATION;

EID: 15444375341     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M410310200     Document Type: Article

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