Nonalcoholic steatohepatitis, insulin resistance, and metabolic syndrome: Further evidence for an etiologic association

Hepatology

Volumn 35, Issue 2, 2002, Pages 367-372

  Pagano, Gianfranco ^a   Pacini, Giovanni ^b   Musso, Giovanni ^a   Gambino, Roberto ^a   Mecca, Fabio ^a   Depetris, Nadia ^a   Cassader, Maurizio ^a   David, Ezio ^c   Cavallo Perin, Paolo ^a   Rizzetto, Mario ^a  

^a UNIVERSITY OF TURIN   (Italy)

^b CNR   (Italy)

^c UNIVERSITY OF TURIN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

C PEPTIDE; GLUCOSE; INSULIN;

ADULT; ARTICLE; BODY MASS; CLINICAL ARTICLE; DISEASE ASSOCIATION; FATTY LIVER; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE INTOLERANCE; HEPATITIS; HISTOPATHOLOGY; HORMONAL REGULATION; HUMAN; HYPERINSULINEMIA; INSULIN BLOOD LEVEL; INSULIN RELEASE; INSULIN RESISTANCE; INSULIN SENSITIVITY; MALE; METABOLIC DISORDER; ORAL GLUCOSE TOLERANCE TEST; PATHOGENESIS; PRIORITY JOURNAL; SYNDROME;

EID: 18244385511     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1053/jhep.2002.30690     Document Type: Article

References (37)

1. Non-alcoholic steatohepatitis: Another disease of affluence
2. Steatohepatitis: A tale of two "hits"?
3. Nonalcoholic fatty liver disease: A spectrum of clinical and pathological severity
4. Prognosis in nonalcoholic steatohepatitis
5. Cryptogenic cirrhosis: Clinical characterisation and risk factors for underlying disease
6. Nonalcoholic steatohepatitis: An expanded clinical entity
7. Idiopathic steatohepatitis in childhood; a multicenter retrospective study
8. Nonalcoholic steatohepatitis
9. The natural history of nonalcoholic steatohepatitis: A follow-up study of forty-two patients for up to 21 years
10. Liver pathology and the metabolic syndrome X in severe obesity
11. Role of insulin resistance in human disease (Syndrome X): An expanded definition
12. Definition, diagnosis and classification of diabetes mellitus and its complications. Part I. Diagnosis and classification of diabetes mellitus. Provisional report of a WHO consultation
13. Comment of the provisional report from the WHO consultation
14. Physiologic evaluation of factors controlling glucose tolerance in man
15. Insulin secretion and hepatic extraction in humans by minimal modeling of C-peptide and insulin kinetics
16. Mathematical models of insulin secretion in physiological and clinical investigations
17. Toward physiological understanding of glucose tolerance. Minimal model approach
18. Estimation of beta-cell secretion and insulin hepatic extraction by the minimal modelling technique
19. Alcohollike liver disease in nonalcoholics. A clinical and histologic comparison with alcohol-induced liver injury
20. A reverse-hybridization assay for the rapid and simultaneous detection of nine HFE gene mutations
21. Fatty liver-an additional and treatable feature of the insulin resistance syndrome
22. Insulin resistance in cirrhosis: Prolonged reduction of hyperinsulinemia normalizes insulin sensitivity
23. Hyperinsulinemia of chronic active hepatitis: Impaired insulin removal rather than pancreatic hypersecretion
24. Insulin sensitivity, insulin secretion and glucose effectiveness in diabetic and non-diabetic cirrhotic patients
25. Insulin secretion, clearance, and action on glucose metabolism in cirrhotic patients
26. Beta-cell response and insulin hepatic extraction in noncirrhotic alcoholic patients soon after withdrawal
27. Quantifcation of the relationship between insulin sensitivity and β-cell function in human subjects. Evidence for a hyperbolic function
28. Effect of body mass index and fat distribution on insulin sensitivity, secretion and clearance in nonobese healthy men
29. Prevalence of NIDDM and impaired glucose tolerance in Italy: An OGTT-based population study
30. Obesity increases sensitivity to endotoxin liver injury: Implications for the pathogenesis of steatohepatitis
31. Resistin: A new hormone that links obesity with type 2 diabetes
32. Increase hepatic iron concentration in non-alcoholic steatohepatitis is associated with increased fibrosis
33. Insulin resistance-associated hepatic iron overload
34. Insulin resistance and hyperinsulinemia in homozygous β-thalassemia
35. Comparison of insulin sensitivity tests across a range of glucose tolerance from normal to diabetes
36. A pilot study of a thiazolidinedione, troglitazone, in nonalcoholic steatohepatitis