-
1
-
-
0032982409
-
The role of the CD95 system in chemotherapy
-
Broxterman HJA (ed) Churchill Livingstone, Edinburgh
-
Debatin KM (1999) The role of the CD95 system in chemotherapy. In: Broxterman HJA (ed) Drug resistance updates. Churchill Livingstone, Edinburgh, pp 85-90
-
(1999)
Drug Resistance Updates
, pp. 85-90
-
-
Debatin, K.M.1
-
2
-
-
0035525733
-
Cellular stress response and apoptosis in cancer therapy
-
Herr I, Debatin KM (2001) Cellular stress response and apoptosis in cancer therapy. Blood 98:2603-2614
-
(2001)
Blood
, vol.98
, pp. 2603-2614
-
-
Herr, I.1
Debatin, K.M.2
-
3
-
-
0030980994
-
Anticancer drugs, programmed cell death and the immune system: Defining new roles in an old play
-
Debatin, KM (1997) Anticancer drugs, programmed cell death and the immune system: defining new roles in an old play. J Natl Cancer Inst 89:750-753
-
(1997)
J Natl Cancer Inst
, vol.89
, pp. 750-753
-
-
Debatin, K.M.1
-
4
-
-
0034630167
-
Induction of apoptosis by cancer chemotherapy
-
Kaufmann SH, Earnshaw WC (2000) Induction of apoptosis by cancer chemotherapy. Exp Cell Res 256:42-49
-
(2000)
Exp Cell Res
, vol.256
, pp. 42-49
-
-
Kaufmann, S.H.1
Earnshaw, W.C.2
-
5
-
-
0033820092
-
Positive and negative regulation of apoptotic pathways by cytotoxic agents in hematological malignancies
-
Solary E, Droin N, Bettaieb A, Corcos L, Dimanche-Boitrel MT, Garrido C (2000) Positive and negative regulation of apoptotic pathways by cytotoxic agents in hematological malignancies. Leukemia 14:1833-1849
-
(2000)
Leukemia
, vol.14
, pp. 1833-1849
-
-
Solary, E.1
Droin, N.2
Bettaieb, A.3
Corcos, L.4
Dimanche-Boitrel, M.T.5
Garrido, C.6
-
7
-
-
0033773114
-
Apoptosis in cancer: Cause and cure
-
Kaufmann SH, Gores GJ (2000) Apoptosis in cancer: cause and cure. Bioessays 22:1007-1017
-
(2000)
Bioessays
, vol.22
, pp. 1007-1017
-
-
Kaufmann, S.H.1
Gores, G.J.2
-
8
-
-
0034641918
-
The biochemistry of apoptosis
-
Hengartner MO (2000) The biochemistry of apoptosis. Nature 407:770-777
-
(2000)
Nature
, vol.407
, pp. 770-777
-
-
Hengartner, M.O.1
-
9
-
-
0034641963
-
Defying death after DNA damage
-
Rich T, Allen RL, Wyllie AH (2000) Defying death after DNA damage. Nature 407:777-783
-
(2000)
Nature
, vol.407
, pp. 777-783
-
-
Rich, T.1
Allen, R.L.2
Wyllie, A.H.3
-
10
-
-
0008290616
-
Diverse functions of JNK signaling and c-Jun in stress response and apoptosis
-
Leppa S, Bohmann D (1999) Diverse functions of JNK signaling and c-Jun in stress response and apoptosis. Oncogene 18:6158-6162
-
(1999)
Oncogene
, vol.18
, pp. 6158-6162
-
-
Leppa, S.1
Bohmann, D.2
-
11
-
-
0034644522
-
Signal transduction by the JNK group of MAP kinases
-
Davis RJ (2000) Signal transduction by the JNK group of MAP kinases. Cell 103:239-252
-
(2000)
Cell
, vol.103
, pp. 239-252
-
-
Davis, R.J.1
-
12
-
-
0034719680
-
The transcription factor NF-kB: Control of oncogenesis and cancer therapy resistance
-
Mayo MW, Baldwin AS (2000) The transcription factor NF-kB: control of oncogenesis and cancer therapy resistance. Biochim Biophys Acta 1470:M55-M62
-
(2000)
Biochim Biophys Acta
, vol.1470
-
-
Mayo, M.W.1
Baldwin, A.S.2
-
13
-
-
0032575750
-
Caspases: Enemies within
-
Thornberry N, Lazebnik Y (1998) Caspases: enemies within. Science 281:1312-1316
-
(1998)
Science
, vol.281
, pp. 1312-1316
-
-
Thornberry, N.1
Lazebnik, Y.2
-
14
-
-
0033153086
-
The role of caspases in development, immunity, and apoptotic signal transduction: Lessons from knockout mice
-
Los M, Wesselborg S, Schulze-Osthoff K (1999) The role of caspases in development, immunity, and apoptotic signal transduction: lessons from knockout mice. Immunity 10:629-639
-
(1999)
Immunity
, vol.10
, pp. 629-639
-
-
Los, M.1
Wesselborg, S.2
Schulze-Osthoff, K.3
-
16
-
-
0032785181
-
Serial killers: Ordering caspase activation events in apoptosis
-
Slee EA, Adrain C, Martin SJ (1999) Serial killers: ordering caspase activation events in apoptosis. Cell Death Differ 6:1067-1074
-
(1999)
Cell Death Differ
, vol.6
, pp. 1067-1074
-
-
Slee, E.A.1
Adrain, C.2
Martin, S.J.3
-
17
-
-
0033938117
-
Life and death decisions: Regulation of apoptosis by proteolysis of signaling molecules
-
Utz PJ, Anderson P (2000) Life and death decisions: regulation of apoptosis by proteolysis of signaling molecules. Cell Death Differ 7:589-602
-
(2000)
Cell Death Differ
, vol.7
, pp. 589-602
-
-
Utz, P.J.1
Anderson, P.2
-
18
-
-
0032885388
-
Mammalian caspases: Structure, activation, substrates, and functions during apoptosis
-
Earnshaw WC, Martins LM, Kaufmann SH (1999) Mammalian caspases: structure, activation, substrates, and functions during apoptosis. Annu Rev Biochem 68:383-424
-
(1999)
Annu Rev Biochem
, vol.68
, pp. 383-424
-
-
Earnshaw, W.C.1
Martins, L.M.2
Kaufmann, S.H.3
-
19
-
-
0024470862
-
Induction of endonucleolytic DNA cleavage in human acute myelogenous leukemia cells by etoposide, camptothecin, and other cytotoxic anticancer drugs: A cautionary note
-
Kaufmann SH (1989) Induction of endonucleolytic DNA cleavage in human acute myelogenous leukemia cells by etoposide, camptothecin, and other cytotoxic anticancer drugs: a cautionary note. Cancer Res 49:5870-5878
-
(1989)
Cancer Res
, vol.49
, pp. 5870-5878
-
-
Kaufmann, S.H.1
-
20
-
-
0030762122
-
Cross-resistance of CD95- and drug-induced apoptosis as a consequence of deficient activation of caspases (ICE/Ced-3 proteases)
-
Los M, Herr I, Friesen C, Fulda S, Schulze-Osthoff K, Debatin KM (1997) Cross-resistance of CD95-and drug-induced apoptosis as a consequence of deficient activation of caspases (ICE/Ced-3 proteases). Blood 90:3118-3129
-
(1997)
Blood
, vol.90
, pp. 3118-3129
-
-
Los, M.1
Herr, I.2
Friesen, C.3
Fulda, S.4
Schulze-Osthoff, K.5
Debatin, K.M.6
-
21
-
-
0035937420
-
Cell death inhibition: Keeping caspases in check
-
Goyal L (2001) Cell death inhibition: keeping caspases in check. Cell 104:805-808
-
(2001)
Cell
, vol.104
, pp. 805-808
-
-
Goyal, L.1
-
22
-
-
0032877668
-
Dysregulation of apoptosis in cancer
-
Reed JC (1999) Dysregulation of apoptosis in cancer. J Clin Oncol 17:2941-2953
-
(1999)
J Clin Oncol
, vol.17
, pp. 2941-2953
-
-
Reed, J.C.1
-
23
-
-
0033579297
-
Does cancer therapy trigger cell suicide?
-
Finkel E (1999) Does cancer therapy trigger cell suicide? Science 286:2256-2258
-
(1999)
Science
, vol.286
, pp. 2256-2258
-
-
Finkel, E.1
-
26
-
-
0033047235
-
Apoptosis without caspases: An inefficient molecular guillotine?
-
Borner C, Monney L (1999) Apoptosis without caspases: an inefficient molecular guillotine? Cell Death Differ 6:497-507
-
(1999)
Cell Death Differ
, vol.6
, pp. 497-507
-
-
Borner, C.1
Monney, L.2
-
27
-
-
0033832629
-
Noncaspase proteases in apoptosis
-
Johnson DE (2000) Noncaspase proteases in apoptosis. Leukemia 14:1695-1703
-
(2000)
Leukemia
, vol.14
, pp. 1695-1703
-
-
Johnson, D.E.1
-
28
-
-
0035433420
-
Four deaths and a funeral: From caspases to alternative mechanisms
-
Leist M, Jaattela M (2001) Four deaths and a funeral: from caspases to alternative mechanisms. Nat Rev Mol Cell Biol 2:589-598
-
(2001)
Nat Rev Mol Cell Biol
, vol.2
, pp. 589-598
-
-
Leist, M.1
Jaattela, M.2
-
29
-
-
0033791574
-
Control of apoptotic DNA degradation
-
Ferri KF, Kroemer G (2000) Control of apoptotic DNA degradation. Nat Cell Biol 2:E63-E64
-
(2000)
Nat Cell Biol
, vol.2
-
-
Ferri, K.F.1
Kroemer, G.2
-
30
-
-
0034617449
-
Apoptosis-inducing factor (AIF): A ubiquitous mitochondrial oxidoreductase involved in apoptosis
-
Daugas E, Nochy D, Ravagnan L, Loeffler M, Susin SA, Zamzami N, Kroemer G (2000) Apoptosis-inducing factor (AIF): a ubiquitous mitochondrial oxidoreductase involved in apoptosis. FEBS Lett 476:118-123
-
(2000)
FEBS Lett
, vol.476
, pp. 118-123
-
-
Daugas, E.1
Nochy, D.2
Ravagnan, L.3
Loeffler, M.4
Susin, S.A.5
Zamzami, N.6
Kroemer, G.7
-
31
-
-
0032526268
-
Apoptosis signaling by death receptors
-
Schulze-Osthoff K, Ferrari D, Los M, Wesselborg S, Peter ME (1998) Apoptosis signaling by death receptors. Eur J Biochem 4:439-459
-
(1998)
Eur J Biochem
, vol.4
, pp. 439-459
-
-
Schulze-Osthoff, K.1
Ferrari, D.2
Los, M.3
Wesselborg, S.4
Peter, M.E.5
-
32
-
-
0034641898
-
CD95's deadly mission in the immune system
-
Krammer PH (2000) CD95's deadly mission in the immune system. Nature 407:789-95
-
(2000)
Nature
, vol.407
, pp. 789-795
-
-
Krammer, P.H.1
-
33
-
-
0034630161
-
The CD95 (APO-1/Fas) and the TRAIL (APO-2L) apoptosis systems
-
Walczak H, Krammer PH (2000) The CD95 (APO-1/Fas) and the TRAIL (APO-2L) apoptosis systems. Exp Cell Res 256:58-66
-
(2000)
Exp Cell Res
, vol.256
, pp. 58-66
-
-
Walczak, H.1
Krammer, P.H.2
-
35
-
-
0034068601
-
Mitochondrial control of cell death
-
Kroemer G, Reed JC (2000) Mitochondrial control of cell death. Nat Med 6:513-519
-
(2000)
Nat Med
, vol.6
, pp. 513-519
-
-
Kroemer, G.1
Reed, J.C.2
-
37
-
-
0034785591
-
A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death
-
Suzuki Y, Imai Y, Nakayama H, Takahashi K, Takio K, Takahashi R (2001) A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death. Mol Cell 8:613-621
-
(2001)
Mol Cell
, vol.8
, pp. 613-621
-
-
Suzuki, Y.1
Imai, Y.2
Nakayama, H.3
Takahashi, K.4
Takio, K.5
Takahashi, R.6
-
38
-
-
0034616945
-
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
-
Du C, Fang M, Li Y, Li L, Wang X (2000) Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell 102:33-42
-
(2000)
Cell
, vol.102
, pp. 33-42
-
-
Du, C.1
Fang, M.2
Li, Y.3
Li, L.4
Wang, X.5
-
39
-
-
0034616942
-
Identification of Diablo, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins
-
Verhagen AM, Ekert PG, Pakusch M, Silke J, Connolly LM, Reid GE, Moritz RL, Simpson RJ, Vaux DL (2000) Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins. Cell 102:43-53
-
(2000)
Cell
, vol.102
, pp. 43-53
-
-
Verhagen, A.M.1
Ekert, P.G.2
Pakusch, M.3
Silke, J.4
Connolly, L.M.5
Reid, G.E.6
Moritz, R.L.7
Simpson, R.J.8
Vaux, D.L.9
-
40
-
-
0034630330
-
Protein complexes activate distinct caspase cascades in death receptor and stress-induced apoptosis
-
Bratton SB, MacFarlane M, Cain K, Cohen GM (2000) Protein complexes activate distinct caspase cascades in death receptor and stress-induced apoptosis. Exp Cell Res 256:27-33
-
(2000)
Exp Cell Res
, vol.256
, pp. 27-33
-
-
Bratton, S.B.1
MacFarlane, M.2
Cain, K.3
Cohen, G.M.4
-
41
-
-
0035369143
-
The mitochondrial apoptosome: A killer unleashed by the cytochrome seas
-
Adrain C, Martin SJ (2001) The mitochondrial apoptosome: a killer unleashed by the cytochrome seas. Trends Biochem Sci 26:390-397
-
(2001)
Trends Biochem Sci
, vol.26
, pp. 390-397
-
-
Adrain, C.1
Martin, S.J.2
-
42
-
-
0035811496
-
Endonuclease G is an apoptotic DNase when released from mitochondria
-
Li LY, Luo X, Wang X (2001) Endonuclease G is an apoptotic DNase when released from mitochondria. Nature 412:95-99
-
(2001)
Nature
, vol.412
, pp. 95-99
-
-
Li, L.Y.1
Luo, X.2
Wang, X.3
-
43
-
-
0035895056
-
Receptor- and mitochondrial-mediated apoptosis in acute leukemia: A translational view
-
Schimmer AD, Hedley DW, Penn LZ, Minden MD (2001) Receptor-and mitochondrial-mediated apoptosis in acute leukemia: a translational view. Blood 98:3541-3553
-
(2001)
Blood
, vol.98
, pp. 3541-3553
-
-
Schimmer, A.D.1
Hedley, D.W.2
Penn, L.Z.3
Minden, M.D.4
-
44
-
-
0034676089
-
Cross-talk in cell death signaling
-
Roy S, Nicholson DW (2000) Cross-talk in cell death signaling. J Exp Med 192:21-26
-
(2000)
J Exp Med
, vol.192
, pp. 21-26
-
-
Roy, S.1
Nicholson, D.W.2
-
45
-
-
0029935682
-
Involvement of the CD95 (APO-1/FAS) receptor/ligand system in drug-induced apoptosis in leukemia cells
-
Friesen C, Herr I, Krammer PH, Debatin KM (1996) Involvement of the CD95 (APO-1/FAS) receptor/ligand system in drug-induced apoptosis in leukemia cells. Nat Med 2:574-577
-
(1996)
Nat Med
, vol.2
, pp. 574-577
-
-
Friesen, C.1
Herr, I.2
Krammer, P.H.3
Debatin, K.M.4
-
47
-
-
0030752603
-
The CD95 (APO-1/Fas) system mediates drug-induced apoptosis in neuroblastoma cells
-
Fulda S, Sieverts H, Friesen C, Herr I, Debatin KM (1997) The CD95 (APO-1/Fas) system mediates drug-induced apoptosis in neuroblastoma cells. Cancer Res 7:3823-3829
-
(1997)
Cancer Res
, vol.7
, pp. 3823-3829
-
-
Fulda, S.1
Sieverts, H.2
Friesen, C.3
Herr, I.4
Debatin, K.M.5
-
48
-
-
0031966318
-
Chemosensitivity of solid tumor cells is associated with activation of the CD95 system
-
Fulda S, Los M, Friesen C, Debatin KM (1998) Chemosensitivity of solid tumor cells is associated with activation of the CD95 system. Int J Cancer 76:105-114
-
(1998)
Int J Cancer
, vol.76
, pp. 105-114
-
-
Fulda, S.1
Los, M.2
Friesen, C.3
Debatin, K.M.4
-
49
-
-
0031762951
-
Activation of the CD95 (APO-1/Fas) pathway in drug- and γ-irradiation-induced apoptosis of brain tumor cells
-
Fulda S, Scaffidi C, Pietsch T, Krammer PH, Peter ME, Debatin KM (1998) Activation of the CD95 (APO-1/Fas) pathway in drug-and γ-irradiation- induced apoptosis of brain tumor cells. Cell Death Differ 5:884-893
-
(1998)
Cell Death Differ
, vol.5
, pp. 884-893
-
-
Fulda, S.1
Scaffidi, C.2
Pietsch, T.3
Krammer, P.H.4
Peter, M.E.5
Debatin, K.M.6
-
50
-
-
0032189535
-
Molecular ordering of apoptosis induced by anticancer drugs in neuroblastoma cells
-
Fulda S, Susin SA, Kroemer G, Debatin KM (1998) Molecular ordering of apoptosis induced by anticancer drugs in neuroblastoma cells. Cancer Res 58:4453-4460
-
(1998)
Cancer Res
, vol.58
, pp. 4453-4460
-
-
Fulda, S.1
Susin, S.A.2
Kroemer, G.3
Debatin, K.M.4
-
51
-
-
0033970949
-
Functional CD95 ligand and CD95 DISC in activation-induced cell death and doxorubicin-induced apoptosis in leukemic T cells
-
Fulda S, Strauss G, Meyer E, Debatin KM (2000) Functional CD95 ligand and CD95 DISC in activation-induced cell death and doxorubicin-induced apoptosis in leukemic T cells. Blood 95:301-308
-
(2000)
Blood
, vol.95
, pp. 301-308
-
-
Fulda, S.1
Strauss, G.2
Meyer, E.3
Debatin, K.M.4
-
52
-
-
0035279153
-
Cell type specific activation of death receptor and mitochondrial pathways in drug-induced apoptosis
-
Fulda S, Meyer E, Susin SA, Kroemer G, Debatin KM (2001) Cell type specific activation of death receptor and mitochondrial pathways in drug-induced apoptosis. Oncogene 20:1063-1075
-
(2001)
Oncogene
, vol.20
, pp. 1063-1075
-
-
Fulda, S.1
Meyer, E.2
Susin, S.A.3
Kroemer, G.4
Debatin, K.M.5
-
53
-
-
0030670626
-
Activation of CD95 (APO-1/Fas) signaling by ceramide mediates cancer therapy-induced apoptosis
-
Herr I, Wilhelm D, Bohler T, Angel P, Debatin KM (1997) Activation of CD95 (APO-1/Fas) signaling by ceramide mediates cancer therapy-induced apoptosis. EMBO J 16:6200-6208
-
(1997)
EMBO J
, vol.16
, pp. 6200-6208
-
-
Herr, I.1
Wilhelm, D.2
Bohler, T.3
Angel, P.4
Debatin, K.M.5
-
54
-
-
0030808385
-
Thymine-less death in colon carcinoma cells is mediated via fas signaling
-
Houghton JA, Harwood FG, Tillman DM (1997) Thymine-less death in colon carcinoma cells is mediated via fas signaling. Proc Natl Acad Sci U S A 94:8144-8149
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 8144-8149
-
-
Houghton, J.A.1
Harwood, F.G.2
Tillman, D.M.3
-
55
-
-
0031743648
-
p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs
-
Muller M, Wilder S, Bannasch D, Israeli D, Lehlbach K, Li-Weber M, Friedman SL, Galle PR, Stremmel W, Oren M, Krammer PH (1998) p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs. J Exp Med 188:2033-2045
-
(1998)
J Exp Med
, vol.188
, pp. 2033-2045
-
-
Muller, M.1
Wilder, S.2
Bannasch, D.3
Israeli, D.4
Lehlbach, K.5
Li-Weber, M.6
Friedman, S.L.7
Galle, P.R.8
Stremmel, W.9
Oren, M.10
Krammer, P.H.11
-
56
-
-
0040419494
-
Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1/Fas) receptor/ligand system and involves activation of wild-type p53
-
Muller M, Strand S, Hug H, Heinemann EM, Walczak H, Hofmann WJ, Stremmel W, Krammer PH, Galle PR (1997) Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1/Fas) receptor/ligand system and involves activation of wild-type p53. J Clin Invest 99:403-413
-
(1997)
J Clin Invest
, vol.99
, pp. 403-413
-
-
Muller, M.1
Strand, S.2
Hug, H.3
Heinemann, E.M.4
Walczak, H.5
Hofmann, W.J.6
Stremmel, W.7
Krammer, P.H.8
Galle, P.R.9
-
57
-
-
0032014073
-
DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-kappa B and AP-1
-
Kasibhatla S, Brunner T, Genestier L, Echeverri F, Mahboubi A, Green DR (1998) DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-kappa B and AP-1. Mol Cell 1:543-551
-
(1998)
Mol Cell
, vol.1
, pp. 543-551
-
-
Kasibhatla, S.1
Brunner, T.2
Genestier, L.3
Echeverri, F.4
Mahboubi, A.5
Green, D.R.6
-
58
-
-
0033796587
-
A novel AP-1 element in the CD95 ligand promoter is required for induction of apoptosis in hepatocellular carcinoma cells upon treatment with anticancer drugs
-
Eichhorst ST, Muller M, Li-Weber M, Schulze-Bergkamen H, Angel P, Krammer PH (2000) A novel AP-1 element in the CD95 ligand promoter is required for induction of apoptosis in hepatocellular carcinoma cells upon treatment with anticancer drugs. Mol Cell Biol 20:7826-7837
-
(2000)
Mol Cell Biol
, vol.20
, pp. 7826-7837
-
-
Eichhorst, S.T.1
Muller, M.2
Li-Weber, M.3
Schulze-Bergkamen, H.4
Angel, P.5
Krammer, P.H.6
-
59
-
-
0035134514
-
The chemotherapeutic drug 5-fluorouracil induces apoptosis in mouse thymocytes in vivo via activation of the CD95 (APO-1/Fas) system
-
Eichhorst ST, Muerkoster S, Weigand MA, Krammer PH (2001) The chemotherapeutic drug 5-fluorouracil induces apoptosis in mouse thymocytes in vivo via activation of the CD95 (APO-1/Fas) system. Cancer Res 61:243-248
-
(2001)
Cancer Res
, vol.61
, pp. 243-248
-
-
Eichhorst, S.T.1
Muerkoster, S.2
Weigand, M.A.3
Krammer, P.H.4
-
60
-
-
0033587708
-
Herpes simplex virus thymidine kinase/ganciclovir-induced apoptosis involves ligand-independent death receptor aggregation and activation of caspases
-
Beltinger C, Fulda S, Kammertoens T, Meyer E, Uckert W, Debatin KM (1999) Herpes simplex virus thymidine kinase/ganciclovir-induced apoptosis involves ligand-independent death receptor aggregation and activation of caspases. Proc Natl Acad Sci U S A 96:8699-8704
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 8699-8704
-
-
Beltinger, C.1
Fulda, S.2
Kammertoens, T.3
Meyer, E.4
Uckert, W.5
Debatin, K.M.6
-
61
-
-
0033168685
-
Myeloma cells selected for resistance to CD95-mediated apoptosis are not cross-resistant to cytotoxic drugs: Evidence for independent mechanisms of caspase activation
-
Landowski TH, Shain KH, Oshiro MM, Buyuksal I, Painter JS, Dalton WS (1999) Myeloma cells selected for resistance to CD95-mediated apoptosis are not cross-resistant to cytotoxic drugs: evidence for independent mechanisms of caspase activation. Blood 94:265-274
-
(1999)
Blood
, vol.94
, pp. 265-274
-
-
Landowski, T.H.1
Shain, K.H.2
Oshiro, M.M.3
Buyuksal, I.4
Painter, J.S.5
Dalton, W.S.6
-
62
-
-
0030806351
-
Comparison of apoptosis in wild-type and Fas-resistant cells: Chemotherapy-induced apoptosis is not dependent on Fas/Fas ligand interactions
-
Eischen CM, Kottke TJ, Martins LM, Basi GS, Tung JS, Earnshaw WC, Leibson PJ, Kaufmann SH (1997) Comparison of apoptosis in wild-type and Fas-resistant cells: chemotherapy-induced apoptosis is not dependent on Fas/Fas ligand interactions. Blood 90:935-943
-
(1997)
Blood
, vol.90
, pp. 935-943
-
-
Eischen, C.M.1
Kottke, T.J.2
Martins, L.M.3
Basi, G.S.4
Tung, J.S.5
Earnshaw, W.C.6
Leibson, P.J.7
Kaufmann, S.H.8
-
63
-
-
0030744833
-
Drug-induced apoptosis is associated with enhanced Fas (Apo-1/CD95) ligand expression but occurs independently of Fas (Apo-1/CD95) signaling in human T-acute lymphatic leukemia cells
-
Villunger A, Egle A, Kos M, Hartmann BL, Geley S, Kofler R, Greil R (1997) Drug-induced apoptosis is associated with enhanced Fas (Apo-1/CD95) ligand expression but occurs independently of Fas (Apo-1/CD95) signaling in human T-acute lymphatic leukemia cells. Cancer Res 57:3331-3334
-
(1997)
Cancer Res
, vol.57
, pp. 3331-3334
-
-
Villunger, A.1
Egle, A.2
Kos, M.3
Hartmann, B.L.4
Geley, S.5
Kofler, R.6
Greil, R.7
-
64
-
-
7144263731
-
FADD: Essential for embryo development and signaling from some, but not all, inducers of apoptosis
-
Yeh WC, Pompa JL, McCurrach ME, Shu HB, Elia AJ, Shahinian A, Ng M, Wakeham A, Khoo W, Mitchell K, El-Deiry WS, Lowe SW, Goeddel DV, Mak TW (1998) FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis. Science 279:1954-1958
-
(1998)
Science
, vol.279
, pp. 1954-1958
-
-
Yeh, W.C.1
Pompa, J.L.2
McCurrach, M.E.3
Shu, H.B.4
Elia, A.J.5
Shahinian, A.6
Ng, M.7
Wakeham, A.8
Khoo, W.9
Mitchell, K.10
El-Deiry, W.S.11
Lowe, S.W.12
Goeddel, D.V.13
Mak, T.W.14
-
65
-
-
0032143986
-
Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally
-
Varfolomeev EE, Schuchmann M, Luria V, Chiannilkulchai N, Beckmann JS, Mett IL, Rebrikov D, Brodianski VM, Kemper OC, Kollet O, Lapidot T, Soffer D, Sobe T, Avraham KB, Goncharov T, Holtmann H, Lonai P, Wallach D (1998) Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally. Immunity 9:267-276
-
(1998)
Immunity
, vol.9
, pp. 267-276
-
-
Varfolomeev, E.E.1
Schuchmann, M.2
Luria, V.3
Chiannilkulchai, N.4
Beckmann, J.S.5
Mett, I.L.6
Rebrikov, D.7
Brodianski, V.M.8
Kemper, O.C.9
Kollet, O.10
Lapidot, T.11
Soffer, D.12
Sobe, T.13
Avraham, K.B.14
Goncharov, T.15
Holtmann, H.16
Lonai, P.17
Wallach, D.18
-
66
-
-
0032493870
-
Differential requirement for caspase 9 in apoptotic pathways in vivo
-
Hakem R, Hakem A, Duncan GS, Henderson JT, Woo M, Soengas MS, Elia A, de la Pompa JL, Kagi D, Khoo W, Potter J, Yoshida R, Kaufman SA, Lowe SW, Penninger JM, Mak TW (1998) Differential requirement for caspase 9 in apoptotic pathways in vivo. Cell 94:339-352
-
(1998)
Cell
, vol.94
, pp. 339-352
-
-
Hakem, R.1
Hakem, A.2
Duncan, G.S.3
Henderson, J.T.4
Woo, M.5
Soengas, M.S.6
Elia, A.7
De La Pompa, J.L.8
Kagi, D.9
Khoo, W.10
Potter, J.11
Yoshida, R.12
Kaufman, S.A.13
Lowe, S.W.14
Penninger, J.M.15
Mak, T.W.16
-
67
-
-
0032544564
-
Apaf1 is required for mitochondrial pathways of apoptosis and brain development
-
Yoshida H, Kong YY, Yoshida R, Elia AJ, Hakem A, Hakem R, Penninger JM, Mak TW (1998) Apaf1 is required for mitochondrial pathways of apoptosis and brain development. Cell 94:739-750
-
(1998)
Cell
, vol.94
, pp. 739-750
-
-
Yoshida, H.1
Kong, Y.Y.2
Yoshida, R.3
Elia, A.J.4
Hakem, A.5
Hakem, R.6
Penninger, J.M.7
Mak, T.W.8
-
68
-
-
0032536771
-
Two CD95 (APO-1/Fas) signaling pathways
-
Scaffidi C, Fulda S, Srinivasan A, Friesen C, Li F, Tomaselli KJ, Debatin KM, Krammer PH, Peter ME (1998) Two CD95 (APO-1/Fas) signaling pathways. EMBO J 17:1675-1687
-
(1998)
EMBO J
, vol.17
, pp. 1675-1687
-
-
Scaffidi, C.1
Fulda, S.2
Srinivasan, A.3
Friesen, C.4
Li, F.5
Tomaselli, K.J.6
Debatin, K.M.7
Krammer, P.H.8
Peter, M.E.9
-
69
-
-
0033610008
-
Differences in expression of pro-caspases in small cell and non-small cell lung carcinoma
-
Joseph B, Ekedahl J, Sirzen F, Lewensohn R, Zhivotovsky B (1999) Differences in expression of pro-caspases in small cell and non-small cell lung carcinoma. Biochem Biophys Res Commun 262:381-387
-
(1999)
Biochem Biophys Res Commun
, vol.262
, pp. 381-387
-
-
Joseph, B.1
Ekedahl, J.2
Sirzen, F.3
Lewensohn, R.4
Zhivotovsky, B.5
-
70
-
-
0040298568
-
Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis
-
Janicke RU, Sprengart ML, Wati MR, Porter AG (1998) Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis. J Biol Chem 273:9357-9360
-
(1998)
J Biol Chem
, vol.273
, pp. 9357-9360
-
-
Janicke, R.U.1
Sprengart, M.L.2
Wati, M.R.3
Porter, A.G.4
-
71
-
-
0035132464
-
Reconstitution of caspase 3 sensitizes MCF-7 breast cancer cells to doxorubicin- and etoposide-induced apoptosis
-
Yang XH, Sladek TL, Liu X, Butler BR, Froelich CJ, Thor AD (2001) Reconstitution of caspase 3 sensitizes MCF-7 breast cancer cells to doxorubicin-and etoposide-induced apoptosis. Cancer Res 61:348-354
-
(2001)
Cancer Res
, vol.61
, pp. 348-354
-
-
Yang, X.H.1
Sladek, T.L.2
Liu, X.3
Butler, B.R.4
Froelich, C.J.5
Thor, A.D.6
-
72
-
-
0034066405
-
Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN
-
Teitz T, Wei T, Valentine MB, Vanin EF, Grenet J, Valentine VA, Behm FG, Look AT, Lahti JM, Kidd VJ (2000) Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN. Nat Med 6:529-535
-
(2000)
Nat Med
, vol.6
, pp. 529-535
-
-
Teitz, T.1
Wei, T.2
Valentine, M.B.3
Vanin, E.F.4
Grenet, J.5
Valentine, V.A.6
Behm, F.G.7
Look, A.T.8
Lahti, J.M.9
Kidd, V.J.10
-
73
-
-
0035855626
-
Sensitization for death receptor- or drug-induced apoptosis by re-expression of caspase-8 through demethylation or gene transfer
-
Fulda S, Kufer MU, Meyer E, van Valen F, Dockhorn-Dworniczak B, Debatin KM (2001) Sensitization for death receptor-or drug-induced apoptosis by re-expression of caspase-8 through demethylation or gene transfer. Oncogene 20:5865-5877
-
(2001)
Oncogene
, vol.20
, pp. 5865-5877
-
-
Fulda, S.1
Kufer, M.U.2
Meyer, E.3
Van Valen, F.4
Dockhorn-Dworniczak, B.5
Debatin, K.M.6
-
74
-
-
0032482441
-
Upregulation of CASP genes in human tumor cells undergoing etoposide-induced apoptosis
-
Droin N, Dubrez L, Eymin B, Renvoize C, Breard J, Dimanche-Boitrel MT, Solary E (1998) Upregulation of CASP genes in human tumor cells undergoing etoposide-induced apoptosis. Oncogene 16:2885-2894
-
(1998)
Oncogene
, vol.16
, pp. 2885-2894
-
-
Droin, N.1
Dubrez, L.2
Eymin, B.3
Renvoize, C.4
Breard, J.5
Dimanche-Boitrel, M.T.6
Solary, E.7
-
75
-
-
1542360704
-
IFN γ sensitizes for apoptosis by upregulating caspase-8 expression through the Stat1 pathway
-
in press
-
Fulda S, Debatin KM (2003) IFN γ sensitizes for apoptosis by upregulating caspase-8 expression through the Stat1 pathway. Oncogene (in press)
-
(2003)
Oncogene
-
-
Fulda, S.1
Debatin, K.M.2
-
76
-
-
0033599527
-
STAT-1-independent upregulation of FADD and procaspase-3 and -8 in cancer cells treated with cytotoxic drugs
-
Micheau O, Hammann A, Solary E, Dimanche-Boitrel MT (1999) STAT-1-independent upregulation of FADD and procaspase-3 and -8 in cancer cells treated with cytotoxic drugs. Biochem Biophys Res Commun 256:603-607
-
(1999)
Biochem Biophys Res Commun
, vol.256
, pp. 603-607
-
-
Micheau, O.1
Hammann, A.2
Solary, E.3
Dimanche-Boitrel, M.T.4
-
78
-
-
0034786019
-
BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis
-
Cheng EH, Wei MC, Weiler S, Flavell RA, Mak TW, Lindsten T, Korsmeyer SJ (2001) BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX-and BAK-mediated mitochondrial apoptosis. Mol Cell 8:705-711
-
(2001)
Mol Cell
, vol.8
, pp. 705-711
-
-
Cheng, E.H.1
Wei, M.C.2
Weiler, S.3
Flavell, R.A.4
Mak, T.W.5
Lindsten, T.6
Korsmeyer, S.J.7
-
79
-
-
0028982183
-
Expression of bcl-xL can confer a multidrug resistance phenotype
-
Minn AJ, Rudin CM, Boise LH, Thompson CB (1995) Expression of bcl-xL can confer a multidrug resistance phenotype. Blood 86:1903-1910
-
(1995)
Blood
, vol.86
, pp. 1903-1910
-
-
Minn, A.J.1
Rudin, C.M.2
Boise, L.H.3
Thompson, C.B.4
-
80
-
-
0027164144
-
High expression of bcl-2 protein in acute myeloid leukemia cells is associated with poor response to chemotherapy
-
Campos L, Rouault JP, Sabido O, Oriol P, Roubi N, Vasselon C, Archimbaud E, Magaud JP, Guyotat D (1993) High expression of bcl-2 protein in acute myeloid leukemia cells is associated with poor response to chemotherapy. Blood 81:3091-3096
-
(1993)
Blood
, vol.81
, pp. 3091-3096
-
-
Campos, L.1
Rouault, J.P.2
Sabido, O.3
Oriol, P.4
Roubi, N.5
Vasselon, C.6
Archimbaud, E.7
Magaud, J.P.8
Guyotat, D.9
-
81
-
-
0028944271
-
Expression of the bcl-2 gene family in normal and malignant breast tissue: Low bax-alpha expression in tumor cells correlates with resistance towards apoptosis
-
Bargou RC, Daniel PT, Mapara MY, Bommert K, Wagener C, Kallinich B, Royer HD, Dorken B (1995) Expression of the bcl-2 gene family in normal and malignant breast tissue: low bax-alpha expression in tumor cells correlates with resistance towards apoptosis. Int J Cancer 60:854-859
-
(1995)
Int J Cancer
, vol.60
, pp. 854-859
-
-
Bargou, R.C.1
Daniel, P.T.2
Mapara, M.Y.3
Bommert, K.4
Wagener, C.5
Kallinich, B.6
Royer, H.D.7
Dorken, B.8
-
82
-
-
0033832590
-
Relapse in childhood acute lymphoblastic leukemia is associated with a decrease of the Bax/Bcl-2 ratio and loss of spontaneous caspase-3 processing in vivo
-
Prokop A, Wieder T, Sturm I, Essmann F, Seeger K, Wuchter C, Ludwig WD, Henze G, Dorken B, Daniel PT (2000) Relapse in childhood acute lymphoblastic leukemia is associated with a decrease of the Bax/Bcl-2 ratio and loss of spontaneous caspase-3 processing in vivo. Leukemia 14:1606-1613
-
(2000)
Leukemia
, vol.14
, pp. 1606-1613
-
-
Prokop, A.1
Wieder, T.2
Sturm, I.3
Essmann, F.4
Seeger, K.5
Wuchter, C.6
Ludwig, W.D.7
Henze, G.8
Dorken, B.9
Daniel, P.T.10
-
83
-
-
0344348993
-
Analysis of the p53/BAX pathway in colorectal cancer: Low BAX is a negative prognostic factor in patients with resected liver metastases
-
8?. Sturm I, Kohne CH, Wolff G, Petrowsky H, Hillebrand T, Hauptmann S, Lorenz M, Dorken B, Daniel PT (1999) Analysis of the p53/BAX pathway in colorectal cancer: low BAX is a negative prognostic factor in patients with resected liver metastases. J Clin Oncol 17:1364-1374
-
(1999)
J Clin Oncol
, vol.17
, pp. 1364-1374
-
-
Sturm, I.1
Kohne, C.H.2
Wolff, G.3
Petrowsky, H.4
Hillebrand, T.5
Hauptmann, S.6
Lorenz, M.7
Dorken, B.8
Daniel, P.T.9
-
84
-
-
0035871439
-
Analysis of p53/BAX/p16(ink4a/CDKN2) in esophageal squamous cell carcinoma: High BAX and p16(ink4a/CDKN2) identifies patients with good prognosis
-
Sturm I, Petrowsky H, Volz R, Lorenz M, Radetzki S, Hillebrand T, Wolff G, Hauptmann S, Dorken B, Daniel PT (2001) Analysis of p53/BAX/p16(ink4a/CDKN2) in esophageal squamous cell carcinoma: high BAX and p16(ink4a/CDKN2) identifies patients with good prognosis. J Clin Oncol 19:2272-2281
-
(2001)
J Clin Oncol
, vol.19
, pp. 2272-2281
-
-
Sturm, I.1
Petrowsky, H.2
Volz, R.3
Lorenz, M.4
Radetzki, S.5
Hillebrand, T.6
Wolff, G.7
Hauptmann, S.8
Dorken, B.9
Daniel, P.T.10
-
85
-
-
0033082995
-
IAP family proteins-suppressors of apoptosis
-
Deveraux QL, Reed JC (1999) IAP family proteins-suppressors of apoptosis. Genes Dev 13:239-252
-
(1999)
Genes Dev
, vol.13
, pp. 239-252
-
-
Deveraux, Q.L.1
Reed, J.C.2
-
87
-
-
0034266807
-
BIRinging chromosomes through cell division-and survivin' the experience
-
Reed JC, Bischoff JR (2000) BIRinging chromosomes through cell division-and survivin' the experience. Cell 102:545-548
-
(2000)
Cell
, vol.102
, pp. 545-548
-
-
Reed, J.C.1
Bischoff, J.R.2
-
88
-
-
17144438370
-
Expression and prognostic significance of IAP-family genes in human cancers and myeloid leukemias
-
Tamm I, Kornblau SM, Segall H, Krajewski S, Welsh K, Kitada S, Scudiero DA, Tudor G, Qui YH, Monks A, Andreeff M, Reed JC (2000) Expression and prognostic significance of IAP-family genes in human cancers and myeloid leukemias. Clin Cancer Res 6:1796-1803
-
(2000)
Clin Cancer Res
, vol.6
, pp. 1796-1803
-
-
Tamm, I.1
Kornblau, S.M.2
Segall, H.3
Krajewski, S.4
Welsh, K.5
Kitada, S.6
Scudiero, D.A.7
Tudor, G.8
Qui, Y.H.9
Monks, A.10
Andreeff, M.11
Reed, J.C.12
-
89
-
-
0033768666
-
Expression and prognostic significance of survivin in de novo acute myeloid leukaemia
-
Adida C, Recher C, Raffoux E, Daniel MT, Taksin AL, Rousselot P, Sigaux F, Degos L, Altieri DC, Dombret H (2000) Expression and prognostic significance of survivin in de novo acute myeloid leukaemia. Br J Haematol 111:196-203
-
(2000)
Br J Haematol
, vol.111
, pp. 196-203
-
-
Adida, C.1
Recher, C.2
Raffoux, E.3
Daniel, M.T.4
Taksin, A.L.5
Rousselot, P.6
Sigaux, F.7
Degos, L.8
Altieri, D.C.9
Dombret, H.10
-
90
-
-
0032554527
-
Anti-apoptosis gene, survivin, and prognosis of neuroblastoma
-
Adida C, Berrebi D, Peuchmaur M, Reyes-Mugica M, Altieri DC (1998) Anti-apoptosis gene, survivin, and prognosis of neuroblastoma. Lancet 351:882-883
-
(1998)
Lancet
, vol.351
, pp. 882-883
-
-
Adida, C.1
Berrebi, D.2
Peuchmaur, M.3
Reyes-Mugica, M.4
Altieri, D.C.5
-
91
-
-
17744379360
-
Human ovarian cancer and cisplatin resistance: Possible role of inhibitor of apoptosis proteins
-
Li J, Feng Q, Kim JM, Schneiderman D, Liston P, Li M, Vanderhyden B, Faught W, Fung MF, Senterman M, Korneluk RG, Tsang BK (2001) Human ovarian cancer and cisplatin resistance: possible role of inhibitor of apoptosis proteins. Endocrinology 142:370-380
-
(2001)
Endocrinology
, vol.142
, pp. 370-380
-
-
Li, J.1
Feng, Q.2
Kim, J.M.3
Schneiderman, D.4
Liston, P.5
Li, M.6
Vanderhyden, B.7
Faught, W.8
Fung, M.F.9
Senterman, M.10
Korneluk, R.G.11
Tsang, B.K.12
-
92
-
-
0034644712
-
XIAP regulates DNA damage-induced apoptosis downstream of caspase-9 cleavage
-
2000275
-
Datta R, Oki E, Endo K, Biedermann V, Ren J, Kufe D (2000) XIAP regulates DNA damage-induced apoptosis downstream of caspase-9 cleavage. J Biol Chem 2000275:31733-31738
-
(2000)
J Biol Chem
, pp. 31733-31738
-
-
Datta, R.1
Oki, E.2
Endo, K.3
Biedermann, V.4
Ren, J.5
Kufe, D.6
-
93
-
-
0035912060
-
Intracellular mechanisms of TRAIL: Apoptosis through mitochondrial- dependent and -independent pathways
-
Suliman A, Lam A, Datta R, Srivastava RK (2000) Intracellular mechanisms of TRAIL: apoptosis through mitochondrial-dependent and -independent pathways. Oncogene 20:2122-2133
-
(2000)
Oncogene
, vol.20
, pp. 2122-2133
-
-
Suliman, A.1
Lam, A.2
Datta, R.3
Srivastava, R.K.4
-
94
-
-
0036341291
-
Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo
-
Fulda S, Wick W, Debatin K-M (2002) Smac agonists sensitize for Apo2L/TRAIL-or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo. Nat Med 8(8):808-815
-
(2002)
Nat Med
, vol.8
, Issue.8
, pp. 808-815
-
-
Fulda, S.1
Wick, W.2
Debatin, K.-M.3
-
95
-
-
0037515714
-
Peptides teargeting caspase inhibitors
-
Tamm I, Trepel M, Cardó-Vila M, Sun Y, Welsh K, Cabezas E, Swatterthwait A, Arap W, Reed JC (2003) Peptides teargeting caspase inhibitors. J Bio Chem 278(16):14401-14405
-
(2003)
J Bio Chem
, vol.278
, Issue.16
, pp. 14401-14405
-
-
Tamm, I.1
Trepel, M.2
Cardó-Vila, M.3
Sun, Y.4
Welsh, K.5
Cabezas, E.6
Swatterthwait, A.7
Arap, W.8
Reed, J.C.9
-
96
-
-
0034719680
-
The transcription factor NF-kB: Control of oncogenesis and cancer therapy resistance
-
Mayo MW, Baldwin AS (2000) The transcription factor NF-kB: control of oncogenesis and cancer therapy resistance. Biochim Biophys Acta 1470:M55-M62
-
(2000)
Biochim Biophys Acta
, vol.1470
-
-
Mayo, M.W.1
Baldwin, A.S.2
-
97
-
-
0034738961
-
Autoamplification of apoptosis following ligation of CD95L, TRAIL- and TNF-α
-
Herr I Posovszky C, Di Marzio L, Cifone MG, Böhler T, Debatin K-M (2000) Autoamplification of apoptosis following ligation of CD95L, TRAIL- and TNF-α. Oncogene 19(37):4255-4262
-
(2000)
Oncogene
, vol.19
, Issue.37
, pp. 4255-4262
-
-
Herr, I.1
Posovszky, C.2
Di Marzio, L.3
Cifone, M.G.4
Böhler, T.5
Debatin, K.-M.6
-
98
-
-
0032941792
-
JNK/SAPK activity is not sufficient for anticancer therapy-induced apoptosis involving CD95L, TRAIL, and TNF-α
-
Herr I, Wilhelm D, Böhler T, Angel P, Debatin K-M (1999) JNK/SAPK activity is not sufficient for anticancer therapy-induced apoptosis involving CD95L, TRAIL, and TNF-α. Int J Cancer 80:417-424
-
(1999)
Int J Cancer
, vol.80
, pp. 417-424
-
-
Herr, I.1
Wilhelm, D.2
Böhler, T.3
Angel, P.4
Debatin, K.-M.5
-
99
-
-
0033040818
-
JNK/SAPK activity contributes to TRAIL-induced apoptosis
-
Herr I, Wilhelm D, Meyer E, Jeremias I, Angel P, Debatin K-M (1999) JNK/SAPK activity contributes to TRAIL-induced apoptosis. Cell Death Differ 6:130-135
-
(1999)
Cell Death Differ
, vol.6
, pp. 130-135
-
-
Herr, I.1
Wilhelm, D.2
Meyer, E.3
Jeremias, I.4
Angel, P.5
Debatin, K.-M.6
-
100
-
-
0030670626
-
Activation of CD95 (APO-1/Fas) signaling by ceramide mediates cancer therapy-induced apoptosis
-
Herr I, Böhler T, Wilhelm D, Angel P, Debatin K-M (1997) Activation of CD95 (APO-1/Fas) signaling by ceramide mediates cancer therapy-induced apoptosis. EMBO J 16:6200-6208
-
(1997)
EMBO J
, vol.16
, pp. 6200-6208
-
-
Herr, I.1
Böhler, T.2
Wilhelm, D.3
Angel, P.4
Debatin, K.-M.5
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