Relapse in childhood acute lymphoblastic leukemia is associated with a decrease of the Bax/Bcl-2 ratio and loss of spontaneous caspase-3 processing in vivo

Leukemia

Volumn 14, Issue 9, 2000, Pages 1606-1613

  Prokop, A ^a   Wieder, T ^a   Sturm, I ^a   Emann, F ^a   Seeger, K ^a   Wuchter, C ^a   Ludwig, W D ^a   Henze, G ^a   Dorken B ^a   Daniel, P T ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Apoptosis; Bax expression; Caspase 3 processing; Relapsed childhood acute lymphoblastic leukemia; Videodensitometry; Western blot

Indexed keywords

CASPASE 3; PROTEIN BAX; PROTEIN BCL 2;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ADULT; AMINO ACID SEQUENCE; APOPTOSIS; ARTICLE; CANCER RECURRENCE; CANCER SURVIVAL; CHILD; CONTROLLED STUDY; DRUG RESISTANCE; ENZYME ACTIVATION; EXON; FEMALE; FRAMESHIFT MUTATION; GENE LOCUS; HUMAN; HUMAN CELL; LEUKEMOGENESIS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN PROCESSING; SIGNAL TRANSDUCTION; STATISTICAL ANALYSIS; VIDEODENSITOMETRY; WESTERN BLOTTING;

EID: 0033832590     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2401866     Document Type: Article

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