The COP/DET/FUS proteins - Regulators of eukaryotic growth and development

Seminars in Cell and Developmental Biology

Volumn 11, Issue 6, 2000, Pages 495-503

  Schwechheimer, Claus ^a   Deng, Xing Wang ^a  

^a YALE UNIVERSITY   (United States)

Author keywords

COP1; COP9 signalosome; Photomorphogenesis; Proteasome; Protein degradation

Indexed keywords

COP PROTEIN; DET PROTEIN; FUS PROTEIN; MUTANT PROTEIN; PROTEASOME; PROTEIN SUBUNIT; UNCLASSIFIED DRUG; VEGETABLE PROTEIN;

GENE LOCUS; GENETIC ANALYSIS; PLANT GROWTH; PLANT SEED; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN INTERACTION; REVIEW; SEQUENCE HOMOLOGY;

ARABIDOPSIS; EUKARYOTA;

EID: 0034491482     PISSN: 10849521     EISSN: None     Source Type: Journal    
DOI: 10.1006/scdb.2000.0203     Document Type: Article

References (63)

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8. A complement of ten essential and pleiotropic Arabidopsis COP/DET/FUS genes is necessary for repression of photomorphogenesis in darkness
9. Multiple photoreceptors mediate the light-induced reduction of GUS-COP1 from Arabidopsis hypocotyl nuclei
10. Arabidopsis COP9 is a component of a novel signaling complex mediating light control of development
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12. Arabidopsis homologs of a c-Jun coactivator are present both in monomeric form and in the COP9 complex, and their abundance is differentially affected by the pleiotropic cop/det/fus mutations
13. Arabidopsis cop8 and fus4 mutations define the same gene that encodes subunit 4 of the COP9 signalosome
14. A FUSCA gene of Arabidopsis encodes a novel protein essential for plant development
15. Evidence for FUS6 as a component of the nuclear-localized COP9 complex in Arabidopsis
16. Arabidopsis FUSCA5 encodes a novel phosphoprotein that is a component of the COP9 complex
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20. Arabidopsis COP8, COP1O, and COP11 genes are involved in repression of photomorphogenic development in darkness
21. The COP9/signalosome complex is conserved in fission yeast and has a role in S phase
22. Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor
23. Alien, a highly conserved protein with characteristics of a corepressor for members of the nuclear hormone receptor superfamily
24. Interaction of the corepressor Alien with DAX-1 is abrogated by mutations of DAX-1 involved in adrenal hypoplasia congenita
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26. HIV-1 Vpr interacts with a human 34-kDa mov34 homologue, a cellular factor linked to the G2/M phase transition of the mammalian cell cycle
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28. The COP9 complex is conserved between plants and mammals and is related to the 26S proteasome regulatory complex
29. Characterization and purification of the mammalian COP9 complex, a conserved nuclear regulator initially identified as a repressor of photomorphogenesis in higher plants
30. The COP9 signalosome is essential for development of Drosophila melanogaster
31. The PCI domain: A common theme in three multiprotein complexes
32. Homologues of the 26S proteasome are regulators of transcription and translation
33. A subcomplex of the proteasome regulatory particle required for ubiquitin-conjugate degradation and related to the COP9-signalosome and elF3
34. The ubiquitin system
35. Characterization of two subunits of Arabidopsis 19S proteasome regulatory complex and its possible interaction with the COP9 complex
36. COP9 signalosome-directed c-JUN activation/stabilization is independent of JNK
37. Subunit 3 of the COP9 signal transduction complex is conserved from plants to humans and maps within the Smith-Magenis syndrome critical region in 17p11.2
38. +-dependent transcription and is implicated in the maintenance of chromosome structure
39. JAB1 interacts with both the progesterone receptor and SRC-1
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42. Integrin LFA-1 interacts with the transcriptional co-acitvator JAB1 to modulate AP1 activity
43. Characterization of the mouse JAB1 cDNA and protein
44. JAB1 binds to the intracellular precursor of the lutropin/choriogonadotropin receptor and promotes its degradation
45. The Bcl-3 oncoprotein acts as a bridging factor between NF-κB/Rel and nuclear co-regulators
46. COP1, an Arabidopsis regulatory gene encodes a protein with both a zinc-binding motif and a Gβ homologous domain
47. Mutations in the DET1 gene affect cell-type specific expression of light-regulated genes and chloroplast development in Arabidopsis
48. DET1, a negative regulator of light-mediated development and gene expression in Arabidopsis, encodes a novel nuclear-localized protein
49. Functional dissection of Arabidopsis COP1 reveals specific roles of its three structural modules in light control of seedling development
50. Genetic and molecular analysis of an allelic series of cop1 mutants suggests functional roles for the multiple protein domains
51. Light inactivation of Arabidopsis photomorphogenic repressor COP1 involves a cell-specific regulation of its nucleocytoplasmic partitioning
52. Genetic and developmental control of nuclear accumulation of COP1, a repressor of photomorphogenesis in Arabidopsis
53. Discrete domains mediate the light-responsive nuclear and cytoplasmic localization of Arabidopsis COP1
54. Evidence for functional conservation of a mammalian homologue of the light-responsive plant protein COP1
55. Structural organization and interactions of COP1, a light-regulated developmental switch
56. Arabidopsis COP1 protein specifically interacts in vitro with a cytoskeleton-associated protein, CIP1
57. Molecular interaction between COP1 and HY5 defines a regulatory switch for light control of Arabidopsis development
58. Role of a COP1 interactive protein in mediating light-regulated gene expression in Arabidopsis
59. The RING motif of photomorphogenic repressor COP1 specifically interacts with the RING-H2 motif of a novel Arabidopsis protein
60. The Arabidopsis HY5 gene encodes a bZIP protein that regulates stimulus-induced development of root and hypocotyl
61. Arabidopsis bZIP protein HY5 directly interacts with light-responsive promoters in mediating light control of gene expression
62. Targeted destabilization of HY5 during light-regulated development of Arabidopsis
63. RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination