Inhibitors of multidrug efflux transporters: Their membrane and protein interactions

Mini-Reviews in Medicinal Chemistry

Volumn 5, Issue 2, 2005, Pages 135-151

  Seelig, Anna ^a   Gatlik Landwojtowicz, E ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

Author keywords

And third generation inhibitors; First ; Membrane partitioning; Modulators; P glycoprotein; Second ; Transport kinetics; Transporter binding

Indexed keywords

2,4 BIS(ALLYLAMINO) 6 [4 [[2,2 BIS(4 FLUOROPHENYL)ETHYL]AMINO]PIPERIDINO] 1,3,5 TRIAZINE; 5 [3 (4 DIPHENYLACETYL 1 PIPERAZINYL) 2 HYDROXYPROPOXY]QUINOLINE; ANIPAMIL; BIRICODAR; CHLORPROMAZINE; CYCLOSPORIN A; DEVAPAMIL; DEXNIGULDIPINE; DILTIAZEM; ELACRIDAR; EMOPAMIL; GALLOPAMIL; GLYCOPROTEIN P; GLYCOPROTEIN P INHIBITOR; MACROGOL; MEMBRANE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1; NICARDIPINE; OC 144093; PROGESTERONE; QUINIDINE; RO 112933; TARIQUIDAR; TRIFLUOPERAZINE; TRIMETHOXYBENZOYLYOHIMBINE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VALSPODAR; VERAPAMIL; XR 9051; ZOSUQUIDAR;

BACTERIAL INFECTION; BINDING AFFINITY; CANCER; CLINICAL TRIAL; DRUG PROTEIN BINDING; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG TRANSPORT; ENZYME ACTIVATION; ENZYME INHIBITION; EPILEPSY; HUMAN; HYDROGEN BOND; MULTIDRUG RESISTANCE; MYCOSIS; PARASITOSIS; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN LIPID INTERACTION; PROTEIN PROTEIN INTERACTION; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REVIEW; STRUCTURE ANALYSIS; THERMODYNAMICS; TRANSPORT KINETICS; TREATMENT FAILURE;

EID: 14544269934     PISSN: 13895575     EISSN: None     Source Type: Journal    
DOI: 10.2174/1389557053402693     Document Type: Review

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