메뉴 건너뛰기




Volumn 275, Issue 3, 1998, Pages 405-411

CTG repeats associated with human genetic disease are inherently flexible

Author keywords

CTG repeats; DNA bending; DNA flexibility; DNA structure; Triplet repeat

Indexed keywords

DNA HELIX; DNA REPLICATION; DNA STRUCTURE; FRAGILE X SYNDROME; FRIEDREICH ATAXIA; GENETIC DISORDER; HUMAN; MOLECULAR STABILITY; MYOTONIC DYSTROPHY; PEDIGREE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; REVIEW; TRINUCLEOTIDE REPEAT;

EID: 0032559372     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1997.1502     Document Type: Article
Times cited : (72)

References (41)
  • 1
    • 0029584496 scopus 로고
    • Trinucleotide repeat expansion and human disease
    • Ashley C. T., Warren S. T. Trinucleotide repeat expansion and human disease. Annu. Rev. Genet. 29:1995;703-728.
    • (1995) Annu. Rev. Genet. , vol.29 , pp. 703-728
    • Ashley, C.T.1    Warren, S.T.2
  • 3
    • 0026587142 scopus 로고
    • A theoretical method to predict DNA permutation gel electrophoresis from the sequence
    • Boffelli D., De Santis P., Palleschi A., Risuleo G., Savino M. A theoretical method to predict DNA permutation gel electrophoresis from the sequence. FEBS Letters. 300:1992;175-178.
    • (1992) FEBS Letters , vol.300 , pp. 175-178
    • Boffelli, D.1    De Santis, P.2    Palleschi, A.3    Risuleo, G.4    Savino, M.5
  • 5
    • 0027209077 scopus 로고
    • Evidence for opposite groove-directed curvature of GGGCCC and AAAAA sequence elements
    • Brukner I., Dlakic M., Savic A., Susic S., Pongor S., Suck D. Evidence for opposite groove-directed curvature of GGGCCC and AAAAA sequence elements. Nucl. Acids Res. 21:1993;1025-1029.
    • (1993) Nucl. Acids Res. , vol.21 , pp. 1025-1029
    • Brukner, I.1    Dlakic, M.2    Savic, A.3    Susic, S.4    Pongor, S.5    Suck, D.6
  • 6
    • 0029872258 scopus 로고    scopus 로고
    • A useful role for 'static' models in elucidating the behaviour of DNA in solution
    • Calladine C. R., Drew H. R. A useful role for 'static' models in elucidating the behaviour of DNA in solution. J. Mol. Biol. 257:1996;479-485.
    • (1996) J. Mol. Biol. , vol.257 , pp. 479-485
    • Calladine, C.R.1    Drew, H.R.2
  • 7
    • 0024278548 scopus 로고
    • The instrinsic curvature of DNA in solution
    • Calladine C. R., Drew H. R., McCall M. J. The instrinsic curvature of DNA in solution. J. Mol. Biol. 201:1988;127-137.
    • (1988) J. Mol. Biol. , vol.201 , pp. 127-137
    • Calladine, C.R.1    Drew, H.R.2    McCall, M.J.3
  • 8
    • 0025955262 scopus 로고
    • A study of electrophoretic mobility of DNA in agarose and polyacrylamide gels
    • Calladine C. R., Collis C. M., Drew H. R., Mott M. R. A study of electrophoretic mobility of DNA in agarose and polyacrylamide gels. J. Mol. Biol. 221:1991;981-1005.
    • (1991) J. Mol. Biol. , vol.221 , pp. 981-1005
    • Calladine, C.R.1    Collis, C.M.2    Drew, H.R.3    Mott, M.R.4
  • 10
    • 0028846524 scopus 로고
    • Anomalous rapid electrophoretic mobility of DNA containing triplet repeats associated with human disease genes
    • Chastain P. D., Eichler E. E., Kang S., Nelson D. L., Levene S. D., Sinden R. R. Anomalous rapid electrophoretic mobility of DNA containing triplet repeats associated with human disease genes. Biochemistry. 34:1995;16125-16131.
    • (1995) Biochemistry , vol.34 , pp. 16125-16131
    • Chastain, P.D.1    Eichler, E.E.2    Kang, S.3    Nelson, D.L.4    Levene, S.D.5    Sinden, R.R.6
  • 12
    • 0030003963 scopus 로고    scopus 로고
    • Propeller-twisting of base-pairs and the conformational mobility of dinucleotide steps in DNA
    • el Hassan M. A., Calladine C. R. Propeller-twisting of base-pairs and the conformational mobility of dinucleotide steps in DNA. J. Mol. Biol. 259:1996;95-103.
    • (1996) J. Mol. Biol. , vol.259 , pp. 95-103
    • El Hassan, M.A.1    Calladine, C.R.2
  • 13
    • 17544367055 scopus 로고    scopus 로고
    • Nucleosome assembly on CTG triplet repeats
    • Godde J. S., Wolffe A. P. Nucleosome assembly on CTG triplet repeats. J. Biol. Chem. 271:1996;15222-15229.
    • (1996) J. Biol. Chem. , vol.271 , pp. 15222-15229
    • Godde, J.S.1    Wolffe, A.P.2
  • 14
    • 0028225644 scopus 로고
    • The crystal structure of C-C-A-T-T-A-A-T-G-G. Implications for bending of B -DNA at T-A steps
    • Goodsell D. S., Kaczor-Grzeskowiak M., Dickerson R. E. The crystal structure of C-C-A-T-T-A-A-T-G-G. Implications for bending of B -DNA at T-A steps. J. Mol. Biol. 231:1994;79-96.
    • (1994) J. Mol. Biol. , vol.231 , pp. 79-96
    • Goodsell, D.S.1    Kaczor-Grzeskowiak, M.2    Dickerson, R.E.3
  • 15
    • 0025312950 scopus 로고
    • Sequence-directed curvature of DNA
    • Hagerman P. J. Sequence-directed curvature of DNA. Annu. Rev. Biochem. 59:1990;755-781.
    • (1990) Annu. Rev. Biochem. , vol.59 , pp. 755-781
    • Hagerman, P.J.1
  • 16
    • 0023891939 scopus 로고
    • Influence of DNA sequence on the formation of non-B right-handed helices in oligopurine. Oligopyrimidine inserts in plasmids
    • Hanvey J. C., Klysik J., Wells R. D. Influence of DNA sequence on the formation of non-B right-handed helices in oligopurine. oligopyrimidine inserts in plasmids. J. Biol. Chem. 263:1988;7386-7396.
    • (1988) J. Biol. Chem. , vol.263 , pp. 7386-7396
    • Hanvey, J.C.1    Klysik, J.2    Wells, R.D.3
  • 18
    • 0028289189 scopus 로고
    • Detection of localized DNA flexibility
    • Kahn J. D., Yun E., Crothers D. M. Detection of localized DNA flexibility. Nature. 368:1994;163-166.
    • (1994) Nature , vol.368 , pp. 163-166
    • Kahn, J.D.1    Yun, E.2    Crothers, D.M.3
  • 19
    • 0022477409 scopus 로고
    • DNA bending at adenine - Thymine tracts
    • Koo H. S., Wu H. M., Crothers D. DNA bending at adenine - thymine tracts. Nature. 320:1986;501-506.
    • (1986) Nature , vol.320 , pp. 501-506
    • Koo, H.S.1    Wu, H.M.2    Crothers, D.3
  • 20
    • 0024413864 scopus 로고
    • Understanding the anomalous electrophoresis of bent DNA molecules: A reptation model
    • Levene S. D., Zimm B. H. Understanding the anomalous electrophoresis of bent DNA molecules: a reptation model. Science. 245:1989;396-399.
    • (1989) Science , vol.245 , pp. 396-399
    • Levene, S.D.1    Zimm, B.H.2
  • 21
    • 0027486238 scopus 로고
    • The structure of branched DNA species
    • Lilley D. M. J., Clegg R. M. The structure of branched DNA species. Quart. Rev. Biophys. 26:1993;131-175.
    • (1993) Quart. Rev. Biophys. , vol.26 , pp. 131-175
    • Lilley, D.M.J.1    Clegg, R.M.2
  • 22
    • 0028301832 scopus 로고
    • Electrophoretic evidence that single-stranded regions of one or more nucleotides dramatically increase the flexibility of DNA
    • Mills J. B., Cooper J. P., Hagerman P. J. Electrophoretic evidence that single-stranded regions of one or more nucleotides dramatically increase the flexibility of DNA. Biochemistry. 33:1994;1797-1803.
    • (1994) Biochemistry , vol.33 , pp. 1797-1803
    • Mills, J.B.1    Cooper, J.P.2    Hagerman, P.J.3
  • 23
    • 0030737538 scopus 로고    scopus 로고
    • Trinucleotide repeats associated with human disease
    • Mitas M. Trinucleotide repeats associated with human disease. Nucl. Acids Res. 25:1997;2245-2253.
    • (1997) Nucl. Acids Res. , vol.25 , pp. 2245-2253
    • Mitas, M.1
  • 24
    • 0023513912 scopus 로고
    • The structure of an oligo(dA)-oligo(dT) tract and its biological implications
    • Nelson H. C. M., Finch J. T., Luisi B. F., Klug A. The structure of an oligo(dA)-oligo(dT) tract and its biological implications. Nature. 330:1987;221-226.
    • (1987) Nature , vol.330 , pp. 221-226
    • Nelson, H.C.M.1    Finch, J.T.2    Luisi, B.F.3    Klug, A.4
  • 25
    • 0000541574 scopus 로고    scopus 로고
    • Twenty years of DNA bending
    • R.H. Sarma, & M.H. Sarma. Albany, NY: Adenine Press
    • Olson W. K., Zhurkin V. B. Twenty years of DNA bending. Sarma R. H., Sarma M. H. Biological Structure and Dynamics. 1996;341-366 Adenine Press, Albany, NY.
    • (1996) Biological Structure and Dynamics , pp. 341-366
    • Olson, W.K.1    Zhurkin, V.B.2
  • 26
    • 0027317556 scopus 로고
    • Influence of fluctuations on DNA curvature. A comparison of flexible and static wedge models of intrinsically bent DNA
    • Olson W. K., Marky N. L., Jernigan R. L., Zhurkin V. B. Influence of fluctuations on DNA curvature. A comparison of flexible and static wedge models of intrinsically bent DNA. J. Mol. Biol. 232:1993;530-554.
    • (1993) J. Mol. Biol. , vol.232 , pp. 530-554
    • Olson, W.K.1    Marky, N.L.2    Jernigan, R.L.3    Zhurkin, V.B.4
  • 27
    • 0029059218 scopus 로고
    • Triplet repeat expansion in myotonic dystrophy alters the adjacent chromatin structure
    • Otten A. D., Tapscott S. J. Triplet repeat expansion in myotonic dystrophy alters the adjacent chromatin structure. Proc. Natl Acad. Sci. USA. 92:1995;5465-5469.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 5465-5469
    • Otten, A.D.1    Tapscott, S.J.2
  • 28
    • 0029883805 scopus 로고    scopus 로고
    • Alternative DNA structures within the trinucleotide repeats of the myotonic dystrophy and fragile X locus
    • Pearson C. E., Sinden R. R. Alternative DNA structures within the trinucleotide repeats of the myotonic dystrophy and fragile X locus. Biochemistry. 35:1996;5041-5053.
    • (1996) Biochemistry , vol.35 , pp. 5041-5053
    • Pearson, C.E.1    Sinden, R.R.2
  • 29
    • 0030752987 scopus 로고    scopus 로고
    • Human MSH2 binds to slipped homoduplex and heteroduplex DNA structures within the trinucloetide repeats of the myotonic dystrophy loci
    • Pearson C. E., Ewel A., Acharya S., Fishel R. A., Sinden R. R. Human MSH2 binds to slipped homoduplex and heteroduplex DNA structures within the trinucloetide repeats of the myotonic dystrophy loci. Hum. Mol. Genet. 6:1997;1117-1123.
    • (1997) Hum. Mol. Genet. , vol.6 , pp. 1117-1123
    • Pearson, C.E.1    Ewel, A.2    Acharya, S.3    Fishel, R.A.4    Sinden, R.R.5
  • 30
    • 0024974069 scopus 로고
    • Sequence dependence of DNA conformational flexibility
    • Sarai A., Mazur J., Nussinov R., Jernigan R. L. Sequence dependence of DNA conformational flexibility. Biochemistry. 28:1989;7842-7849.
    • (1989) Biochemistry , vol.28 , pp. 7842-7849
    • Sarai, A.1    Mazur, J.2    Nussinov, R.3    Jernigan, R.L.4
  • 31
    • 0021022977 scopus 로고
    • Energetics of DNA twisting. I. Relation between twist and cyclization probability
    • Shore D., Baldwin R. L. Energetics of DNA twisting. I. Relation between twist and cyclization probability. J. Mol. Biol. 170:1983;957-981.
    • (1983) J. Mol. Biol. , vol.170 , pp. 957-981
    • Shore, D.1    Baldwin, R.L.2
  • 32
    • 0001191247 scopus 로고
    • DNA flexibility studied by covalent closure of short fragments into circles
    • Shore D., Langowski J., Baldwin R. L. DNA flexibility studied by covalent closure of short fragments into circles. Proc. Natl Acad. Sci. USA. 78:1981;4833-4837.
    • (1981) Proc. Natl Acad. Sci. USA , vol.78 , pp. 4833-4837
    • Shore, D.1    Langowski, J.2    Baldwin, R.L.3
  • 33
    • 0025144957 scopus 로고
    • Effects of DNA sequence and histone-histone interactions on nucleosome placement
    • Shrader T. E., Crothers D. M. Effects of DNA sequence and histone-histone interactions on nucleosome placement. J. Mol. Biol. 216:1990;69-84.
    • (1990) J. Mol. Biol. , vol.216 , pp. 69-84
    • Shrader, T.E.1    Crothers, D.M.2
  • 35
    • 0027014233 scopus 로고
    • DNA structure, mutations, and human genetic disease
    • Sinden R. R., Wells R. D. DNA structure, mutations, and human genetic disease. Curr. Opin. Biotech. 3:1992;612-622.
    • (1992) Curr. Opin. Biotech. , vol.3 , pp. 612-622
    • Sinden, R.R.1    Wells, R.D.2
  • 36
    • 0025355712 scopus 로고
    • Application of the method of T4 phage DNA ligase-catalyzed ring-closure to the study of DNA structure. II. NaCl-dependence of DNA flexibility and helical repeat
    • Taylor W. H., Hagerman P. J. Application of the method of T4 phage DNA ligase-catalyzed ring-closure to the study of DNA structure. II. NaCl-dependence of DNA flexibility and helical repeat. J. Mol. Biol. 212:1990;363-376.
    • (1990) J. Mol. Biol. , vol.212 , pp. 363-376
    • Taylor, W.H.1    Hagerman, P.J.2
  • 37
    • 0001498045 scopus 로고
    • Static persistence length of DNA
    • M.H. Sarma, & R.H. Sarma. Albany, NY: Adenine Press
    • Trifonov E. N., Tan R. K. Z., Harvey S. C. Static persistence length of DNA. Sarma M. H., Sarma R. H. Structure and Expression. 1988;243-254 Adenine Press, Albany, NY.
    • (1988) Structure and Expression , pp. 243-254
    • Trifonov, E.N.1    Tan, R.K.Z.2    Harvey, S.C.3
  • 38
    • 0027941198 scopus 로고
    • Preferential nucleosome assembly at DNA triplet repeats from the myotonic dystrophy gene
    • Wang Y.-H., Amirhaeri S., Kang S., Wells R. D., Griffith J. D. Preferential nucleosome assembly at DNA triplet repeats from the myotonic dystrophy gene. Science. 265:1994;669-671.
    • (1994) Science , vol.265 , pp. 669-671
    • Wang, Y.-H.1    Amirhaeri, S.2    Kang, S.3    Wells, R.D.4    Griffith, J.D.5
  • 39
    • 0024829512 scopus 로고
    • Initiation of transcription on nucleosomal templates
    • Wolffe A. P., Drew H. R. Initiation of transcription on nucleosomal templates. Proc. Natl Acad. Sci. USA. 86:1989;9817-9821.
    • (1989) Proc. Natl Acad. Sci. USA , vol.86 , pp. 9817-9821
    • Wolffe, A.P.1    Drew, H.R.2
  • 40
    • 0021268779 scopus 로고
    • The locus of sequence-directed and protein-induced DNA bending
    • Wu H. M., Crothers D. M. The locus of sequence-directed and protein-induced DNA bending. Nature. 308:1984;509-513.
    • (1984) Nature , vol.308 , pp. 509-513
    • Wu, H.M.1    Crothers, D.M.2
  • 41
    • 0026668168 scopus 로고
    • Problems and prospects in the theory of gel electrophoresis of DNA
    • Zimm B. H., Levene S. D. Problems and prospects in the theory of gel electrophoresis of DNA. Qart. Rev. Biophys. 25:1992;171-204.
    • (1992) Qart. Rev. Biophys. , vol.25 , pp. 171-204
    • Zimm, B.H.1    Levene, S.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.