Proteasome-mediated degradation of transcriptional activators correlates with activation domain potency in vivo

EMBO Journal

Volumn 18, Issue 22, 1999, Pages 6439-6447

  Molinari, Elizabeth ^a   Gilman, Michael ^a   Natesan, Sridaran ^a  

^a ARIAD PHARMACEUTICALS INC   (United States)

Author keywords

Activation domain potency; Degradation; Proteasome; Transcription; Transcriptional activator

Indexed keywords

PROTEASOME; RAPAMYCIN; RECEPTOR PROTEIN; TRANSCRIPTION FACTOR;

ARTICLE; CONTROLLED STUDY; GENE EXPRESSION REGULATION; GENE EXPRESSION SYSTEM; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEGRADATION; PROTEIN DNA BINDING; PROTEIN DOMAIN; PROTEIN INTERACTION; TRANSCRIPTION INITIATION;

ANTIGENS, POLYOMAVIRUS TRANSFORMING; BINDING SITES; CYSTEINE ENDOPEPTIDASES; FIBROSARCOMA; FUNGAL PROTEINS; GENE EXPRESSION REGULATION; HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; HUMANS; KINETICS; MULTIENZYME COMPLEXES; PROTEASOME ENDOPEPTIDASE COMPLEX; RECOMBINANT FUSION PROTEINS; SACCHAROMYCES CEREVISIAE PROTEINS; TRANS-ACTIVATION (GENETICS); TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSFECTION; TUMOR CELLS, CULTURED;

MAMMALIA;

EID: 0033571527     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/18.22.6439     Document Type: Article

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