Protein kinase activation and myocardial ischemia/reperfusion injury

Cardiovascular Research

Volumn 61, Issue 3, 2004, Pages 427-436

  Armstrong, Stephen C ^a  

^a East Tennessee State University   (United States)

Author keywords

Apoptosis; Cardiomyocytes; Ischemia; Necrosis; Protein kinases

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN KINASE C; PROTEIN TYROSINE KINASE; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE;

APOPTOSIS; CELL DEATH; CLINICAL PROTOCOL; ENZYME ACTIVATION; ENZYME ACTIVITY; HEART INFARCTION PREVENTION; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART MUSCLE PERFUSION; HEART PROTECTION; IN VITRO STUDY; IN VIVO STUDY; NECROSIS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; REPERFUSION INJURY; REVIEW; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; APOPTOSIS; ENZYME ACTIVATION; HUMANS; ISCHEMIC PRECONDITIONING, MYOCARDIAL; MAP KINASE SIGNALING SYSTEM; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; PROTEIN KINASE C;

EID: 1142309730     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cardiores.2003.09.031     Document Type: Review

References (64)

1. Steenbergen C. The role of p38 mitogen-activated protein kinase in myocardial ischemia/reperfusion injury; relationship to ischemic preconditioning. Basic Res. Cardiol. 97:2002;276-285.
2. Simkovich B.Z., Przyklenk K., Kloner R.A. Role of protein kinase C as a cellular mediator of ischemic preconditioning: a critical review. Cardiovasc. Res. 40:1998;9-22.
3. Prasad M.R., Jones R.M. Enhanced membrane protein kinase C activity in myocardial ischemia. Basic Res. Cardiol. 87:1992;19-26.
4. Yoshida K., Hirata T., Akita Y.et al. Translocation of protein kinase C-alpha, delta, and epsilon isoforms in ischemic rat heart. Biochim. Biophys. Acta. 1317:1996;36-44.
5. Albert C., Ford D. Protein kinase C translocation and PKC dependent protein phosphorylation during myocardial ischemia. Am. J. Physiol. 276:1999;H642-H650. [Heart Circ. Physiol. 45].
6. Liu Y., Ytrehus K., Downey J.M. Evidence that translocation of protein kinase C is a key event during ischemic preconditioning of rabbit myocardium. J. Mol. Cell Cardiol. 26:1994;661-668.
7. Saurin A.T., Pennington D.J., Raat N.J.H., Latchman D.S., Owen M.J., Marber M.S. Targeted disruption of the protein kinase C epsilon gene abolishes the infarct size reduction that follows ischaemic preconditioning of isolated buffer-perfused mouse hearts. Cardiovasc. Res. 55:2002;672-680.
8. Inagaki K., Hahn H.S., Dorn G.W., Mochly-Rosen D. Additive protection of the ischemic heart ex vivo by combined treatment with δ-protein kinase C inhibitor and ε-protein kinase C activator. Circulation. 108:2003;869-875.
9. Ping P., Zhang J., Qiu Y.et al. Ischemic preconditioning induces selective translocation of protein kinase C isoforms ε and η in the heart of conscious rabbits without subcellular redistribution of total protein kinase C activity. Circ. Res. 81:1997;404-414.
10. Bogoyevitch M.A., Gillespie-Brown J., Ketterman A.J.et al. Stimulation of stress-activated mitogen-activated protein kinase subfamilies in perfused heart. p38/RK mitogen-activated protein kinases and c-Jun N-terminal kinases are activated by ischemia/reperfusion. Circ. Res. 79:1996;162-173.
11. Knight R.J., Buxton D.B. Stimulation of c-Jun kinase and mitogen-activated protein kinase by ischemia and reperfusion in the perfused rat heart. Biochem. Biophys. Res. Commun. 218:1996;83-88.
12. Mizukami Y., Yoshida K. Mitogen-activated protein kinase translocates to the nucleus during ischaemia and is activated during reperfusion. Biochem. J. 323:1997;785-790.
13. Omura T., Yoshiyama M., Shimada T.et al. Activation of mitogen activated protein kinases in in vivo ischemia/reperfused myocardium in rat. J. Mol. Cell. Cardiol. 31:1999;1269.
14. Yin T., Sandhu G., Wolfgang C.D.et al. Tissue specific pattern of stress kinase activation in ischemic-reperfused heart and kidney. J. Biol. Chem. 272:1997;19943-19950.
15. Mizukami Y., Yoshioka K., Morimoto S., Yoshida K. A novel mechanism of JNK1 activation: nuclear translocation and activation of JNK1 during ischemia and reperfusion. J. Biol. Chem. 272:1997;16657-16662.
16. He H., Li H.L., Lin A., Gottlieb R.A. Activation of the JNK pathway is important for cardiomyocyte death in response to simulated ischemia. Cell Death Differ. 6:1999;987-991.
17. Maulik N., Watanabe M., Zu Y.-L.et al. Ischemic preconditioning triggers the activation of MAP kinases and MAPKAP kinase 2 in rat hearts. FEBS Lett. 396:1996;233-237.
18. Weinbrenner C., Liu G.-S., Cohen M.V., Downey J.M. Phosphorylation of tyrosine 182 of p38 mitogen-activated protein kinase correlates with the protection of preconditioning in the rabbit heart. J. Mol. Cell. Cardiol. 29:1997;2383-2391.
19. Marais E., Genade S., Huisamen B., Strijdom J.G., Moolman J.A., Lochner A. Activation of p38 MAPK induced by multi-cycle ischaemic preconditioning protocol is associated with attenuated p38 MAPK activity during sustained ischaemia and reperfusion. J. Mol. Cell Cardiol. 33:2001;769-778.
20. Nakano A., Baines C.P., Kim S.et al. Ischemic preconditioning activates MAPKAPK2 in the isolated rabbit heart: evidence for involvement of p38 MAPK. Circ. Res. 86:2000;144-151.
21. Wang Y., Huang S., Sah V.et al. Cardiac muscle cell hypertrophy and apoptosis induced by distinct members of the p38 mitogen activated protein kinase family. J. Biol. Chem. 273:1998;2161-2168.
22. Tanno M., Bassi R., Gorog D.A.et al. Diverse mechanisms of myocardial p38 mitogen-activated protein kinase activation. Evidence for MKK-independent activation by a TAB1-associated mechanism contributing to injury myocardial ischemia. Circ. Res. 93:2003;254-261.
23. Otsu K., Yamashita N., Nishida K.et al. Disruption of a single copy of the p38 MAPα kinase gene leads to cardioprotection against ischemia-reperfusion. Biochem. Biophys. Res. Commun. 302:2003;56-60.
24. Fryer R.M., Patel H.H., Hsu A.K., Gross G.J. Stress-activated protein kinase phosphorylation during cardioprotection in the ischemic myocardium. Am. J. Physiol. Heart Circ. Physiol. 281:2001;H1184-H1192.
25. Sato M., Cordis G.A., Maulik N., Das D. SAPKs regulation of ischemic preconditioning. Am. J. Physiol. 279:2000;H901-H907.
26. Fryer R.M., Pratt P.F., Hsu A.K., Gross G.J. Differential activation of extracellular signal regulated kinase isoforms in preconditioning and opioid-induced cardioprotection. J. Pharmacol. Exp. Ther. 296:2001;642-649.
27. Mocanu M.M., Bell R.M., Yellon D.M. PI3 kinase and not p42/p44 appears to be implicated in the protection conferred by ischemic preconditioning. J. Mol. Cell. Cardiol. 34:2002;661-668.
28. Ping P., Zhang J., Cao X.et al. PKC-dependent activation of p44/p42 MAPKs during myocardial ischemia-reperfusion in conscious rabbits. Am. J. Physiol. 276:1999;H1468-H1481. [Heart Circ. Physiol. 45].
29. Ping P., Zhang J., Huang S.et al. PKC-dependent activation of p46/p54 JNKs during ischemia preconditioning in conscious rabbits. Am. J. Physiol. 277:1999;H1771-H1785. [Heart Circ. Physiol. 46].
30. Heidkamp M.C., Bayer A.L., Martin J.L., Samarel A.M. Differential activation of mitogen-activated protein kinase cascades and apoptosis by protein kinase C ε and δ in neonatal rat ventricular myocytes. Circ. Res. 89:2001;882-890.
31. Baines C.P., Wang L., Cohen M.V., Downey J.M. Myocardial protection by insulin is dependent on phosphatidylinositol 3-kinase but not protein kinase C or KATP in the isolated rabbit heart. Basic Res. Cardiol. 94:1999;188-198.
32. Tong H., Chen W., Steenbergen C., Murphy E. Ischemic preconditioning activates phosphatidylinositol-3-kinase upstream of protein kinase C. Circ. Res. 87:2000;309-315.
33. Tong H., Imashi K., Steenbergen C., Murphy E. Phosphorylation of glycogen synthase kinase-3β during preconditioning through a phosphatidylinositol-3-kinase-dependent pathway is cardioprotective. Circ. Res. 90:2002;377-379.
34. Krieg T., Qin Q., McIntosh E.C., Cohen M.V., Downey J.M. Ach and adenosine activate PI3-kinase in rabbit hearts through transactivation of receptor tyrosine kinases. Am. J. Physiol. 283:2002;H2322-H2330.
35. Kim A.H., Khursigara G., Sun X., Franke T.F., Chao M.V. Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1. Mol. Cell Biol. 21:2001;893-901.
36. Ping P., Zhang J., Zheng Y.T.et al. Demonstration of selective protein kinase C dependent activation of Src and Lck tyrosine kinases during ischemic preconditioning in conscious rabbits. Circ. Res. 85:1999;542-550.
37. Baines C.P., Wang L., Cohen M.V., Downey J.M. Protein tyrosine kinase is downstream of protein kinase C for ischemic preconditioning's anti-infarct effect in the rabbit heart. J. Mol. Cell. Cardiol. 30:1998;383-392.
38. Ping P., Song C., Zhang J., Guo Y., Cao X., Li R.et al. Formation of protein kinase C (epsilon)-Lck signalling modules confers cardioprotection. J. Clin. Invest. 109:2002;499-507.
39. Brandt D.T., Goerke A., Heuer M.et al. Protein kinase delta induced Src kinase activity via activation of the protein tyrosine phosphatase PTP alpha. J. Biol. Chem. 278:2003;34073-34078.
40. Takeshi Y., Abe J., Lee J.D., Kawakatsu H., Walsh R.A., Berk B.C. Differential regulation of p90 ribosomal S6 kinase and big mitogen-activated protein kinase 1 by ischemia/reperfusion and oxidative stress in perfused guinea pig hearts. Circ. Res. 85:1999;1164-1172.
41. Takeshi Y., Huang Q., Wang T.et al. Src family kinase and adenosine differentially regulate multiple MAP kinases in ischemic myocardium: modulation of MAP kinases activation by ischemic preconditioning. J. Mol. Cell. Cardiol. 33:2001;1989-2005.
42. Elsasser A., Suzuki K., Lorenz-Meyer S., Bode C., Schaper J. The role of apoptosis in myocardial ischemia: a critical appraisal. Basic Res. Cardiol. 96:2001;219-226.
43. Ma X.L., Kumar S., Gao F.et al. Inhibition of p38 mitogen activated protein kinase decreases cardiomyocyte apoptosis and improves cardiac function after myocardial ischemia and reperfusion. Circulation. 99:1999;1685-1691.
44. Vander Heide R.S., Rim D., Hohl C.M., Ganote C.E. An in vitro model of myocardial ischemia utilizing isolated adult rat myocytes. J. Mol. Cell. Cardiol. 22:1990;165-181.
45. Armstrong S.C., Delacey M., Ganote C.E. Phosphorylation state of hsp27 and p38 MAPK during preconditioning and protein phosphatase inhibitor protection of rabbit cardiomyocytes. J. Mol. Cell. Cardiol. 31:1999;555-567.
46. Ge B., Gram H., Di Padova F.et al. MAPKK independent activation of p38 MAPK α mediated by TAB1 dependent auto-phosphorylation of p38 MAPK α Science. 95:2002;1291-1294.
47. Yue T.L., Wang C., Gu J.L.et al. Inhibition of extracellular signal-regulated kinase enhances ischemia/reoxygenation-induced apoptosis in cultured cardiac myocytes and exaggerates reperfusion injury in isolated perfused heart. Circ. Res. 86:2000;692-699.
48. Zhang H., Shi X., Hampong M., Blanis L., Pelech S. Stress induced inhibition of ERK1 and ERK2 by direct interaction with p38 MAP kinase. J. Biol. Chem. 276:2001;6905-6909.
49. Punn A., Mockridge J.W., Farooqui S., Marber M.S., Heads R.J. Sustained activation of p42/p44 mitogen-activated protein kinase during recovery from simulated ischaemia mediates adaptive cytoprotection. Biochem. J. 350:2000;891-899.
50. Mockbridge J.W., Marber M.S., Heads R.J. Activation of Akt during simulated ischemia/reperfusion. Biochem. Biophys. Res. Commun. 270:2000;947-952.
51. Laderoute K.R., Webster K.A. Hypoxia/reoxygenation stimulates Jun kinase activity through redox signaling in cardiac myocytes. Circ. Res. 80:1997;336-344.
52. Dougherty C.J., Kubasiak L.A., Prentice H., Andreka P., Bishopric N.H., Webster K.A. Activation of c-Jun N-terminal kinase promotes survival of cardiac myocytes after oxidative stress. Biochem. J. 362:2002;561-571.
53. Dougherty C.J., Graham R.M., Prentice H., Bishopric N.H., Webster K.A. C-Jun N-terminal kinase functions as a bioenergetic sensor that determines cardiac myocyte fate during hypoxia-reoxygenation. Circulation. 106:2002;II-130. [Abstract].
54. Turner N.A., Fen X., Azhar G., Zhang X., Liu L., Wei J.Y. Oxidative stress induces DNA fragmentation and caspase activation via the c-Jun NH2-terminal kinase pathway in H9c2 cardiac muscle cells. J. Mol. Cell Cardiol. 30:1998;1789-1801.
55. ε translocation via enhanced PKCε-RACK2 interactions: a novel mechanism of NO-triggered activation of PKCε̃ J. Biol. Chem. 277:2002;15021-15027.
56. Andreka P., Zang J., Dougherty C., Slepak T.I., Webster K.A., Bishopric N.H. Cytoprotection by Jun kinase during nitric oxide-induced cardiac myocyte apoptosis. Circ. Res. 88:2001;305-312.
57. Clerk A., Fuller S.J., Michael A., Sugden P.H. Stimulation of "stress-regulated" mitogen-activated protein kinases (stress-activated protein kinases/c-Jun N-terminal kinases and p38-mitogen activated protein kinases) in perfused rat hearts by oxidative and other stresses. J. Biol. Chem. 273:1998;7228-7234.
58. Pham F.H., Sugden P.H., Clerk A. Regulation of protein kinase B and 4E-BP1 by oxidative stress in cardiac myocytes. Circ. Res. 86:2000;1252-1258.
59. Clerk A., Ashour M., Sugden P.H. Stimulation of multiple mitogen-activated protein kinase sub-families by oxidative stress and phosphorylation of the small heat shock protein, HSP25/27 in neonatal ventricular myocytes. Biochem. J. 333:1998;581-589.
60. + exchange in neonatal rat cardiac myocytes. Circ. Res. 82:1998;1053-1062.
61. rsk that are inducible by MAPK. J. Biol. Chem. 273:1998;1496-1505.
62. Bugge E., Ytrehus K. Inhibition of sodium-hydrogen exchange reduces infarct size in the isolated rat heart - a protective additive to ischemic preconditioning. Cardiovasc. Res. 29:1995;269-274.
63. Jensen C., Buch M., Krag T., Hemmings B., Gammeltoft S., Frodin M. 90-Kda Ribosomal S6 kinase is phosphorylated and activated by 3-phosphoinositide-dependent protein kinase-1. J. Biol. Chem. 274:1999;27168-27176.
64. + exchanger-directed protein kinases in the ischemic and ischemic-reperfused rat myocardium. J. Biol. Chem. 276:2001;16113-16122.