Hydrogen peroxide activates mitogen-activated protein kinases and Na+- H+ exchange in neonatal rat cardiac myocytes

Circulation Research

Volumn 82, Issue 10, 1998, Pages 1053-1062

  Sabri, Abdelkarim ^a   Byron, Kenneth L ^a   Samarel, Allen M ^a   Bell, Jeremy ^a   Lucchesi, Pamela A ^a  

^a LOYOLA UNIVERSITY CHICAGO   (United States)

Author keywords

Hydrogen peroxide; Mitogen activated protein kinase; Na+ H+ exchange; Signal transduction

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CATALASE; CHELERYTHRINE; FREE RADICAL; GENISTEIN; HERBIMYCIN A; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE;

AMPLITUDE MODULATION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; DOSE RESPONSE; DOSE TIME EFFECT RELATION; ENZYME ACTIVATION; ENZYME REGULATION; HEART MUSCLE; HEART MUSCLE CONTRACTILITY; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; INHIBITION KINETICS; NEWBORN; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT; SODIUM TRANSPORT;

EID: 0032102273     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.82.10.1053     Document Type: Article

References (44)

1. Goldhaber JI, Weiss JN. Oxygen free radicals and cardiac reperfusion abnormalities. Hypertension. 1992;20:118-127.
2. Zweier J, Rayburn B, Flaherty J, Weisfeldt M. Recombinant superoxide dismutase reduces free radical concentrations in reperfused myocardium. J Clin Invest. 1987;87:1728-1734.
3. Farber NE, Pieper GM, Thomas JP, Gross GJ. Beneficial effects of iloprost in the stunned myocardium. Circ Res. 1988;62:204-215.
4. Bolli R. Mechanism of myocardial "stunning." Circulation. 1990;82:723-728.
5. 2+ exchange in ventricular myocytes. Am J Physiol. 1996;271:H823-H833.
6. Goldhaber JI. Liu E. Excitation-contraction coupling in single-guinea pig ventricular myocytes exposed to hydrogen peroxide. J Physiol (Lond). 1994;477:135-147.
7. Ventura C, Guarnieri C, Caldarera CM. Inhibitory effects of superoxide radicals on cardiac myofibrillar ATPase activity. J Biochem. 1985;34:267-274.
8. + exchange in cardiac physiology and pathophysiology: mediation of myocardial reperfusion injury by the pH paradox. Cardiovasc Res. 1993;27:915-924.
9. Reimer K, Jennings R. Myocardial ischemia, hypoxia, and infarction. In: Fozzard H, Haber E, Jennings R, Katz A, Morgan H, eds. The Heart and Cardiovascular System. Vols 1 and 2. New York, NY: Raven Press Publishers; 1991;1875-1974.
10. + exchanger: an update on structure, regulation and cardiac physiology. Biochem J. 1993;296:273-285.
11. + exchanger, NHE-1, by phosphorylating a set of common sites. J Biol Chem. 1991;266:19166-19171.
12. Dyck JRB, Maddaford TG, Pierce GN, Fliegel L. Induction of expression of the sodium-hydrogen exchanger in rat myocardium. Cardiovasc Res. 1995;29:203-208.
13. + antiporter, glycoprotein of 110 kD. Science. 1990;247:723-726.
14. Lucchesi PA, Berk BC. Regulation of sodium-hydrogen exchange in vascular smooth muscle. Cardiovasc Res. 1995;29:172-177.
15. + exchange in cultured vascular smooth muscle cells: evidence for protein kinase C-dependent and -independent pathways. J Biol Chem. 1987;262:5065-5072.
16. + exchanger. Biochemistry. 1997;36:9151-9158.
17. + exchanger kinase has increased activity in spontaneously hypertensive rat vascular smooth muscle cells. Hypertension. 1997;29:1265-1272.
18. + exchanger (NHE1 isoform) in response to growth factors. J Biol Chem. 1997;272:271-279.
19. Chung Y, Jue T. Cellular response to reperfused oxygen in the postischemic myocardium. Am J Physiol. 1996;271:H687-H695.
20. Rao G. Hydrogen peroxide induces complex formation of SHC-Grb2-SOS with receptor tyrosine kinase and activates Ras and extracellular signal-regulated protein kinases group of mitogen-activated protein kinases. Oncogene. 1996;13:713-719.
21. Wu M-L, Tsai K-L, Wang S-M, Wu J-C, Wang B-S, Lee Y-T. Mechanism of hydrogen peroxide and hydroxyl free radical-induced intracellular acidification in cultured rat cardiac myoblasts. Circ Res. 1996;78:564-572.
22. Sundaresan M, Yu Z-X, Ferrans VJ, Irani K, Finkel T. Requirement for generation of H2O2 for platelet-derived growth factor signal transduction. Science. 1995;270:296-299.
23. Rao GN, Berk BC. Active oxygen species stimulate vascular smooth muscle growth and proto-oncogene expression. Circ Res. 1992;70:593-599.
24. Byron KL, Brezina J, Hwang A, Samarel A, Lucchesi PA. Hydrogen peroxide activates MAP kinases in cardiac myocytes [abstract]. J Mol Cell Cardiol. 1996;28:A198.
25. Samarel AM, Engelmann GL. Contractile activity modulates myosin heavy chain-β expression in neonatal rat heart cells. Am J Physiol. 1991;261:H1067-H0177.
26. 2+-dependent mitogen-activated protein kinase activation in spontaneously hypertensive rat smooth muscle defines a hypertensive signal transduction phenotype. Circ Res. 1996;78:962-979.
27. Thomas JA, Buchsbaum RN, Zimniak A, Racker E. Intracellular pH measurements in Erlich ascites tumor cells utilizing spectroscopic probes in situ. Biochemistry. 1979;81:2210-2218.
28. Roos A, Boron WF. Intracellular pH. Physiol Rev. 1981;61:296-434.
29. 2 in vascular smooth muscle cells. Circ Res. 1995;77:29-36.
30. Sundqvist T, Axelsson KL. The cGMP modulator, LY83583, alters oxygen metabolites differently in cultured endothelial cells and isolated neutrophilic granulocytes. Pharmacol Toxicol. 1993;72:169-174.
31. Aikawa A, Komuro I, Yamazaki Y, Zou Y, Kudoh S, Tanaka M, Shiojima I, Hiroi Y, Yazaki Y. Oxidative stress activates extracellular signal-regulated kinases through src and ras in cultured cardiac myocytes of neonatal rats. J Clin Invest. 1997;100:1813-1821.
32. 2. J Biol Chem. 1996;271:4138-4142.
33. Jiang T, Pak E, Zhang HL, Kline RP, Steinberg SF. Endothelin-dependent actions in cultured AT-1 cardiac myocytes: the role of the ε isoform of protein kinase C. Circ Res. 1996;78:724-736.
34. Bogoyevitcri MA, Gillespie-Brown J, Ketterman AJ, Fuller SJ, Ben-Levy R, Ashworth A, Marshall CJ, Sugden PH. Stimulation of the stress-activated mitogen-activated kinase subfamilies in perfused heart: p38/RK mitogen-activated protein kinases and c-Jun N-terminal kinases are activated by ischemia/reperfusion. Circ Res. 1996;79:162-173.
35. Dikic I, Tokiwa G, Lev S, Courtneidge SA, Schlessinger J. A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation. Nature. 1996;283:547-550.
36. 2+-induced regulation of ion channel and MAP kinase function. Nature. 1995;376:737-745.
37. Sadoshima J, Izumo S. The heterotrimeric G protein-coupled angiotensin II receptor activates p21 via the tyrosine kinase-Shc-Grb2-Sos pathway in cardiac myocytes. EMBO J. 1996;15:775-787.
38. 2 and vanadate in vitro. Biochem Biophys Res Commun. 1992;188:773-779.
39. Zou Y, Komuro I, Yamazaki T, Aikawa R, Kudoh S, Shiojima I, Hiroi Y, Mizuno T, Yazaki Y. Protein kinase C, but not tyrosine kinase or ras, plays a critical role in angiotensin 2-induced activation of Raf-1 kinase and extracellular signal-regulated protein kinases in cardiac myocytes. J Biol Chem. 1996;271:33592-33597.
40. + exchange inhibitors against cardiac injury produced by ischemia/reperfusion, hypoxia/reoxygenation, and the calcium paradox. J Cardiovasc Pharmacol. 1993;21:172-178.
41. + exchange. Am J Physiol. 1988;255:H608-H615.
42. Meng H-P, Pierce GN. Protective effect of 5-(N,N-dimethyl) amiloride on ischemia-reperfusion injury in hearts. Am J Physiol. 1990;258:H1615-H1619.
43. 2+ regulation defective. J Biol Chem. 1994;269:13710-13715.
44. Kaneko M, Masuda H, Suziki HYM, Kobayashi A, Yamazaki N. Modification of contractile proteins by oxygen free radicals in rat heart. Mol Cell Biochem. 1993;125:163-169.