메뉴 건너뛰기




Volumn 270, Issue 3, 2000, Pages 947-952

Activation of Akt during simulated ischemia/reperfusion in cardiac myocytes

Author keywords

Akt protein kinase B; Cardiomyocytes; Ischemia; Ischemia reperfusion; Phosphatidylinositol 3 kinase; Phosphorylation; Src tyrosine kinase; Wortmannin

Indexed keywords

GENISTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; WORTMANNIN;

EID: 0034696810     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2000.2522     Document Type: Article
Times cited : (78)

References (31)
  • 2
    • 0030044744 scopus 로고    scopus 로고
    • Hypoxia and hypoxia/reoxygenation activate Raf-1, mitogen-activated protein kinase kinase, mitogen-activated protein kinase, and S6 kinase in cultured rat cardiac myocytes
    • Seko Y., Tobe K., Ueki K., Kadowaki T., Yazaki Y. Hypoxia and hypoxia/reoxygenation activate Raf-1, mitogen-activated protein kinase kinase, mitogen-activated protein kinase, and S6 kinase in cultured rat cardiac myocytes. Circ. Res. 78:1996;82-90.
    • (1996) Circ. Res. , vol.78 , pp. 82-90
    • Seko, Y.1    Tobe, K.2    Ueki, K.3    Kadowaki, T.4    Yazaki, Y.5
  • 3
    • 0031590460 scopus 로고    scopus 로고
    • PAK, p38 mitogen-activated protein kinase (MAPK), and stress-activated protein kinase (SAPK) in cultured rat cardiac myocytes
    • PAK, p38 mitogen-activated protein kinase (MAPK), and stress-activated protein kinase (SAPK) in cultured rat cardiac myocytes. Biochem. Biophys. Res. Commun. 239:1997;840-844.
    • (1997) Biochem. Biophys. Res. Commun. , vol.239 , pp. 840-844
    • Seko, Y.1    Takahashi, N.2    Tobe, K.3    Kadowaki, T.4    Yazaki, Y.5
  • 4
    • 0030922032 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase translocates to the nucleus during ischemia and is activated during reperfusion
    • Mizukami Y., Yoshida K.-I. Mitogen-activated protein kinase translocates to the nucleus during ischemia and is activated during reperfusion. Biochem. J. 323:1997;785-790.
    • (1997) Biochem. J. , vol.323 , pp. 785-790
    • Mizukami, Y.1    Yoshida, K.-I.2
  • 5
    • 0030582381 scopus 로고    scopus 로고
    • Hypoxia and hypoxia/reoxygenation activate Src family tyrosine kinases and p21ras in cultured rat cardiac myocytes
    • Seko Y., Tobe K., Takahashi M., Kaburagi Y., Kadowaki T., Yazaki Y. Hypoxia and hypoxia/reoxygenation activate Src family tyrosine kinases and p21ras in cultured rat cardiac myocytes. Biochem. Biophys. Res. Commun. 226:1996;530-535.
    • (1996) Biochem. Biophys. Res. Commun. , vol.226 , pp. 530-535
    • Seko, Y.1    Tobe, K.2    Takahashi, M.3    Kaburagi, Y.4    Kadowaki, T.5    Yazaki, Y.6
  • 6
    • 0033584438 scopus 로고    scopus 로고
    • Hypoxia induces activation and subcellular translocation of focal adhesion kinase (p125FAK) in cultured rat cardiac myocytes
    • Seko Y., Takahashi N., Sabe H., Tobe K., Kadowaki T., Nagai R. Hypoxia induces activation and subcellular translocation of focal adhesion kinase (p125FAK) in cultured rat cardiac myocytes. Biochem. Biophys. Res. Commun. 262:1999;290-296.
    • (1999) Biochem. Biophys. Res. Commun. , vol.262 , pp. 290-296
    • Seko, Y.1    Takahashi, N.2    Sabe, H.3    Tobe, K.4    Kadowaki, T.5    Nagai, R.6
  • 7
    • 0031439247 scopus 로고    scopus 로고
    • Cellular functions regulated by Src family kinases
    • Thomas S. M., Brugge J. S. Cellular functions regulated by Src family kinases. Annu. Rev. Cell. Dev. Biol. 13:1997;513-609.
    • (1997) Annu. Rev. Cell. Dev. Biol. , vol.13 , pp. 513-609
    • Thomas, S.M.1    Brugge, J.S.2
  • 8
    • 0029821721 scopus 로고    scopus 로고
    • Activation of RAC-protein kinase by heat shock and hyperosmolarity stress through a pathway independent of phosphatidylinositol 3-kinase
    • Konishi H., Matsuzaki H., Tanaka M., Ono Y., Tokunaga C., Kuroda S., Kikkawa U. Activation of RAC-protein kinase by heat shock and hyperosmolarity stress through a pathway independent of phosphatidylinositol 3-kinase. Proc. Natl. Acad. Sci. USA. 93:1996;7639-7643.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 7639-7643
    • Konishi, H.1    Matsuzaki, H.2    Tanaka, M.3    Ono, Y.4    Tokunaga, C.5    Kuroda, S.6    Kikkawa, U.7
  • 9
    • 0030785701 scopus 로고    scopus 로고
    • Activation of protein kinase B (Akt/RAC-protein kinase) by cellular stress and its association with heat shock protein Hsp27
    • Konishi H., Matsuzaki H., Tanaka M., Takemura Y., Kuroda S., Ono Y., Kikkawa U. Activation of protein kinase B (Akt/RAC-protein kinase) by cellular stress and its association with heat shock protein Hsp27. FEBS Lett. 410:1997;493-498.
    • (1997) FEBS Lett. , vol.410 , pp. 493-498
    • Konishi, H.1    Matsuzaki, H.2    Tanaka, M.3    Takemura, Y.4    Kuroda, S.5    Ono, Y.6    Kikkawa, U.7
  • 10
    • 0030890933 scopus 로고    scopus 로고
    • Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase
    • Ahmed N. N., Grimes H. L., Bellacosa A., Chan T. O., Tsichlis P. N. Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase. Proc. Natl. Acad. Sci. USA. 94:1997;3627-3632.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 3627-3632
    • Ahmed, N.N.1    Grimes, H.L.2    Bellacosa, A.3    Chan, T.O.4    Tsichlis, P.N.5
  • 11
    • 1842333237 scopus 로고    scopus 로고
    • Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt
    • Del Peso L., Gonzalez-Garcia M., Page C., Herrera R., Nunez G. Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt. Science. 278:1997;687-689.
    • (1997) Science , vol.278 , pp. 687-689
    • Del Peso, L.1    Gonzalez-Garcia, M.2    Page, C.3    Herrera, R.4    Nunez, G.5
  • 12
    • 0031770827 scopus 로고    scopus 로고
    • Akt-dependent and -independent survival signaling pathways utilized by insulin-like growth factor I
    • Kulik G., Weber M. J. Akt-dependent and -independent survival signaling pathways utilized by insulin-like growth factor I. Mol Cell Biol. 18:1998;6711-6718.
    • (1998) Mol Cell Biol , vol.18 , pp. 6711-6718
    • Kulik, G.1    Weber, M.J.2
  • 13
    • 0032533546 scopus 로고    scopus 로고
    • 2 or heat shock is mediated by phosphoinositide 3-kinase and not by mitogen-activated protein kinase-activated protein kinase-2
    • 2 or heat shock is mediated by phosphoinositide 3-kinase and not by mitogen-activated protein kinase-activated protein kinase-2. Biochem. J. 336:1998;241-246.
    • (1998) Biochem. J. , vol.336 , pp. 241-246
    • Shaw, M.1    Cohen, P.2    Alessi, D.R.3
  • 14
    • 0029587224 scopus 로고
    • Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
    • Cross D. A. E., Alessi D. R., Cohen P., Andjelkovich M., Hemmings B. A. Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature. 378:1995;785-789.
    • (1995) Nature , vol.378 , pp. 785-789
    • Cross, D.A.E.1    Alessi, D.R.2    Cohen, P.3    Andjelkovich, M.4    Hemmings, B.A.5
  • 16
    • 0030702123 scopus 로고    scopus 로고
    • Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
    • Datta S. R., Dudek H., Tao X., Masters S., Fu H., Gotoh Y., Greenberg M. E. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell. 91:1997;231-241.
    • (1997) Cell , vol.91 , pp. 231-241
    • Datta, S.R.1    Dudek, H.2    Tao, X.3    Masters, S.4    Fu, H.5    Gotoh, Y.6    Greenberg, M.E.7
  • 17
    • 0033517190 scopus 로고    scopus 로고
    • NF-κB is a target of Akt in anti-apoptotic PDGF signaling
    • Romashkova J. A., Makarov S. S. NF-κB is a target of Akt in anti-apoptotic PDGF signaling. Nature. 401:1999;86-89.
    • (1999) Nature , vol.401 , pp. 86-89
    • Romashkova, J.A.1    Makarov, S.S.2
  • 18
    • 0033546439 scopus 로고    scopus 로고
    • Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B
    • Rena G., Guo S., Cichy S. C., Unterman T. G., Cohen P. Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B. J. Biol. Chem. 274:1999;17179-17183.
    • (1999) J. Biol. Chem. , vol.274 , pp. 17179-17183
    • Rena, G.1    Guo, S.2    Cichy, S.C.3    Unterman, T.G.4    Cohen, P.5
  • 20
    • 0030068245 scopus 로고    scopus 로고
    • The ability of heat stress and metabolic preconditioning to protect primary rat cardiac myocytes
    • Cumming D. V. E., Heads R. J., Brand N. J., Yellon D. M., Latchman D. S. The ability of heat stress and metabolic preconditioning to protect primary rat cardiac myocytes. Basic Res. Cardiol. 91:1996;79-85.
    • (1996) Basic Res. Cardiol. , vol.91 , pp. 79-85
    • Cumming, D.V.E.1    Heads, R.J.2    Brand, N.J.3    Yellon, D.M.4    Latchman, D.S.5
  • 21
    • 0029079275 scopus 로고
    • The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase
    • Franke T. F., Yang S.-I., Chan T. O., Datta K., Kazlauskas A., Morrisen D. K., Kaplan D. R., Tsichlis P. N. The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase. Cell. 81:1995;727-736.
    • (1995) Cell , vol.81 , pp. 727-736
    • Franke, T.F.1    Yang, S.-I.2    Chan, T.O.3    Datta, K.4    Kazlauskas, A.5    Morrisen, D.K.6    Kaplan, D.R.7    Tsichlis, P.N.8
  • 22
    • 0030590875 scopus 로고    scopus 로고
    • Molecular basis for the substrate specificity of protein kinase B; Comparison with MAPKAP kinase-1 and p70 S6 kinase
    • Alessi D. R., Caudwell F. B., Andjelkovic M., Hemmings B. A., Cohen P. Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase. FEBS Lett. 399:1996;333-338.
    • (1996) FEBS Lett. , vol.399 , pp. 333-338
    • Alessi, D.R.1    Caudwell, F.B.2    Andjelkovic, M.3    Hemmings, B.A.4    Cohen, P.5
  • 24
    • 0032504745 scopus 로고    scopus 로고
    • Fluid shear stress stimulates phosphorylation of Akt in human endothelial cells: Involvement in suppression of apoptosis
    • Dimmeler S., Assmus B., Hermann C., Haendeler J., Zeiher A. M. Fluid shear stress stimulates phosphorylation of Akt in human endothelial cells: Involvement in suppression of apoptosis. Circ. Res. 83:1998;334-341.
    • (1998) Circ. Res. , vol.83 , pp. 334-341
    • Dimmeler, S.1    Assmus, B.2    Hermann, C.3    Haendeler, J.4    Zeiher, A.M.5
  • 25
    • 0030886770 scopus 로고    scopus 로고
    • Oxidative stress activates extracellular signal-regulated kinases through Src and Ras in cultured cardiac myocytes of neonatal rats
    • Aikawa R., Komuro I., Yamazaki T., Zou Y., Kudoh S., Tanaka M., Shiojima I., Hiroi Y., Yazaki Y. Oxidative stress activates extracellular signal-regulated kinases through Src and Ras in cultured cardiac myocytes of neonatal rats. J. Clin. Invest. 100:1997;1813-1821.
    • (1997) J. Clin. Invest. , vol.100 , pp. 1813-1821
    • Aikawa, R.1    Komuro, I.2    Yamazaki, T.3    Zou, Y.4    Kudoh, S.5    Tanaka, M.6    Shiojima, I.7    Hiroi, Y.8    Yazaki, Y.9
  • 26
    • 0032578005 scopus 로고    scopus 로고
    • Src family tyrosine kinase regulates intracellular pH in cardiomyocytes
    • Puceat M., Roche S., Vassort G. Src family tyrosine kinase regulates intracellular pH in cardiomyocytes. J. Cell Biol. 141:1999;1637-1646.
    • (1999) J. Cell Biol. , vol.141 , pp. 1637-1646
    • Puceat, M.1    Roche, S.2    Vassort, G.3
  • 27
    • 0033578895 scopus 로고    scopus 로고
    • Demonstration of selective protein kinase C-dependent activation of Src and Lck tyrosine kinases during ischemic preconditioning in conscious rabbits
    • Ping P., Zhang N., Zheng Y.-T., Li R. X., Dawn B., Tang X.-L., Takano H., Balafonova Z., Bolli R. Demonstration of selective protein kinase C-dependent activation of Src and Lck tyrosine kinases during ischemic preconditioning in conscious rabbits. Circ. Res. 85:1999;542-550.
    • (1999) Circ. Res. , vol.85 , pp. 542-550
    • Ping, P.1    Zhang, N.2    Zheng, Y.-T.3    Li, R.X.4    Dawn, B.5    Tang, X.-L.6    Takano, H.7    Balafonova, Z.8    Bolli, R.9
  • 28
    • 0033570091 scopus 로고    scopus 로고
    • The mitogen activated protein (MAP) kinase p38 and its upstream activator MAPK kinase kinase 6 are involved in the activation of signal transducer and activator of transcription by hyperosmolarity
    • Bode J. C., Gatsios P., Ludwig S., Rapp U. R., Haussinger D., Heinrich P. C., Graeve L. The mitogen activated protein (MAP) kinase p38 and its upstream activator MAPK kinase kinase 6 are involved in the activation of signal transducer and activator of transcription by hyperosmolarity. J. Biol. Chem. 274:1999;30222-30227.
    • (1999) J. Biol. Chem. , vol.274 , pp. 30222-30227
    • Bode, J.C.1    Gatsios, P.2    Ludwig, S.3    Rapp, U.R.4    Haussinger, D.5    Heinrich, P.C.6    Graeve, L.7
  • 29
    • 0033561559 scopus 로고    scopus 로고
    • The functional synergy between IL-12 and IL-2 involves p38 mitogen-activated protein kinase and is associated with the augmentation of STAT1 serine phosphorylation
    • Gollob J. A., Schnipper C. P., Murphy E. A., Ritz J., Frank D. A. The functional synergy between IL-12 and IL-2 involves p38 mitogen-activated protein kinase and is associated with the augmentation of STAT1 serine phosphorylation. J. Immunol. 162:1999;4472-4481.
    • (1999) J. Immunol. , vol.162 , pp. 4472-4481
    • Gollob, J.A.1    Schnipper, C.P.2    Murphy, E.A.3    Ritz, J.4    Frank, D.A.5
  • 31
    • 0032718056 scopus 로고    scopus 로고
    • Signal transduction pathways that regulate eukaryotic protein synthesis
    • Rhoads R. E. Signal transduction pathways that regulate eukaryotic protein synthesis. J. Biol. Chem. 274:1999;30337-30340.
    • (1999) J. Biol. Chem. , vol.274 , pp. 30337-30340
    • Rhoads, R.E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.