Inhibition of p38 mitogen-activated protein kinase decreases cardiomyocyte apoptosis and improves cardiac function after myocardial ischemia and reperfusion

Circulation

Volumn 99, Issue 13, 1999, Pages 1685-1691

  Ma, Xin L ^a,c   Kumar, Sanjay ^b   Gao, Feng ^a   Louden, Calvert S ^b   Lopez, Bernard L ^a   Christopher, Theodore A ^a   Wang, Chuanlin ^b   Lee, John C ^b   Feuerstein, Giora Z ^b   Yue, Tian Li ^b  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b GLAXOSMITHKLINE   (United Kingdom)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Apoptosis; Contractality; Myocardial infarction; Reperfusion; Signal transduction

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; SYNAPTOPHYSIN;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; ENZYME INHIBITION; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART MUSCLE NECROSIS; HEART MUSCLE REPERFUSION; HEART PROTECTION; NONHUMAN; PRIORITY JOURNAL; RABBIT; SIGNAL TRANSDUCTION;

EID: 0033528695     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.99.13.1685     Document Type: Article

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