Phosphorylation state of hsp27 and p38 MAPK during preconditioning and protein phosphatase inhibitor protection of rabbit cardiomyocytes

Journal of Molecular and Cellular Cardiology

Volumn 31, Issue 3, 1999, Pages 555-567

  Armstrong, S C ^a,b   Delacey, M ^a   Ganote, C E ^a  

^a East Tennessee State University   (United States)

^b EAST TENNESSEE STATE UNIVERSITY   (United States)

Author keywords

Calyculin A; Heat shock protein; Isoelectric focusing; Protein phosphorylation

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CALYCULIN A; HEAT SHOCK PROTEIN 27; MITOGEN ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DEPHOSPHORYLATION; HEART MUSCLE CELL; IMMUNOBLOTTING; ISOELECTRIC FOCUSING; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; TWO DIMENSIONAL GEL ELECTROPHORESIS;

EID: 0033105619     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.1998.0891     Document Type: Article

References (41)

1. Armstrong S, Downey JM, Ganote CE, 1994. Preconditioning of isolated rabbit cardiomyocytes: Induction by metabolic stress and blockade by the adenosine antagonist SPT and calphostin C, a protein kinase C inhibitor. Cardiovas Res 28: 72-77.
2. Armstrong SC, Ganote CE, 1991. Effects of the phospholipase inhibitor mepacrine on irreversible injury in ischemic and metabolically inhibited adult isolated myocytes. Amer J Pathol 138: 545-555.
3. Armstrong SC, Ganote CE, 1994. Preconditioning of isolated rabbit cardiomyocytes: Effects of glycolytic blockade, phorbol esters and ischaemia. Cardiovas Res 28: 1700-1706.
4. Armstrong SC, Ganote CE, 1995. In vitro ischaemic preconditioning of isolated rabbit cardiomyocytes: Effects of selective adenosine receptor blockade and calphostin. C. Cardiovas Res 29: 647-652.
5. Armstrong SC, Hoover DB, Delacey MH, Ganote CE, 1996. Translocation of PKC, protein phosphatase inhibition and preconditioning of rabbit cardiomyocytes. J Mol Cell Cardiol 28: 1479-1492.
6. Armstrong SC, Hoover DB, Shivell LC, Ganote CE, 1997a. Preconditioning of isolated rabbit cardiomyocytes: No evident separation of induction, memory and protection. J Mol Cell Cardiol 29: 2285-2298.
7. Armstrong SC, Kao R, Gao W, Shivell LM, Downey JM, Honkanen R, Ganote CE, 1997b. Comparison of in vitro preconditioning responses of isolated pig and rabbit cardiomyocytes: Effects of a protein phosphatase inhibitor, fostriecin. J Mol Cell Cardiol 29: 3009-3024.
8. Armstrong SC, Gao W, Lane JR, Ganote CE, 1998. Protein phosphatase inhibitors calyculin A and fostriecin protect rabbit cardiomyocytes in late ischemia. J Mol Cell Cardiol 30: 61-73.
9. Barancik M, Htun P, Maeno Y, Zimmerman R, Schaper W, 1997. Differential regulation of distinct protein kinase cascades by ischemia and ischemia/reperfusion in porcine myocardium. Circulation 96: I-252.
10. Beckerle MC, Yeh RK, 1990. Views and reviews. Talin: Role at sites of cell-substratum adhesion. Cell Motil Cytoskel 16: 7-13.
11. Bogoyevitch MA, Gillespie-Brown J, Ketterman AJ, Fullar SJ, Ben-Levy R, Ashworth A, Marshall CJ, Sugden PH, 1996. Stimulation of stress-activated mitogen-activated protein kinase subfamilies in perfused heart. p38/RK mitogen-activated protein kinases and c-Jun N-terminal kinases are activated by ischemia/reperfusion. Circ Res 79: 162-173.
12. Burridge K, Nuckolls G, Otey C, Pavalko F, Simon K, Turner C, 1990. Actin-membrane interaction in focal adhesions. Cell Diff and Develop 32: 337-342.
13. Cairns J, Qin S, Phil R, Tan YH, Guy GR, 1994. Dephosphorylation of the small heat shock protein hsp27 in vivo by protein phosphatase 2A. J Biol Chem 269: 9176-9183.
14. Eaton P, Awad WI, Miller JIA, Hearse DJ and Shattock MJ, 1998. Does translocation of α-crystallin and hsp27 to the myofilaments play a role in ischaemic preconditioning? J Mol Cell Cardiol 30: A19.
15. Freshney NW, Rawlinson L, Guedson F, Jones E, Cowley S, Hsuan J, Saklatvala J 1994. Interleukin activates a novel protein kinase cascade that results in the phosphorylation of hsp27. Cell 78: 1039-1049.
16. Gaestel M, Schröder W, Benndorf R, Lippmann C, Buchner K, Hucho F, Erdmann VA, Bielka H, 1991. Identification of the phosphorylation sites of the murine small heat shock protein hsp25. J Biol Chem 266: 14721-14724.
17. Ganote CE, Vander Heide RS, 1988. Irreversible injury of isolated adult rat myocytes: Osmotic fragility during metabolic inhibition. Am J Path 132: 212-222.
18. Guay J, Lambert H, Gingras-Breton G, Lavoie JN, Huot J, 1997. Regulation of actin filament dynamics by p38 MAP kinase-mediated phosphorylation of heat shock protein 27. J Cell Sci 110: 357-368.
19. Hoch B, Lutsch G, Schlegel WJS, Wallukat G, Bartel S, Krause E, Benndorf R, Karczewski P, 1996. Hsp25 in isolated perfused rat hearts: Localization and response to hyperthermia. Mol Cell Biochem 160/161: 231-239.
20. Huot J, Huole F, Marceau F, Landry J, 1997. Oxidative stress-induced actin reorganization mediated by the p38 mitogen activated protein kinse/heat shock protein 27 pathway in vascular endothelial cells. Circ Res 80: 383-392.
21. Kato K, Hasegawa K, Goto S, Inguma Y, 1994. Dissociation as a result of phosphorylation of an aggregrated form of the small stress protein hsp27. J Biol Chem 269: 11274-11278.
22. Landry J, Huot J, 1995. Review: Modulation of actin dynamics during stress and physiological stimulation by a signaling pathway involving p38 MAP kinase and heat shock protein 27. Biochem Cell Biol 73: 703-707.
23. Landry J, Lambert H, Zhou M, Lavoie J, Hickey E, Weber LA, Anderson CW, 1992. Human hsp27 is phosphorylated at serines 78 and 82 by heat shock and mitogen-activated kinases that recognize the same amino acid motif as S6 kinase II. J Biol Chem 267: 794-803.
24. Larsen JK, Yamboliev IA, Weber LA, and Gerthoffer WT, 1997. Phosphorylation of the 27 kDa heat shock protein via p38 MAP kinase and MAPKAP kinase in smooth muscle. Am J Physiol 273: L930-940.
25. Lavoie J, Lambert H, Hickey E, Weber L, Landry J, 1995. Modulation of cellular thermoresistance and actin filament stability accompanies phosphorylation-induced changes in the oligomeric structure of heat shock protein 27. Mol Cell Biol 15: 505-516.
26. Li S, Piotrowicz RS, Levin EG, Shyy YJ, and Chien, S, 1996. Fluid shear stress induces the phosphorylation of small heat shock proteins in vascular endothelial cells. Am J Physiol 271: C994-1000.
27. Loktionova SA, Ilyinskaya OP, Gabai VL, Kabakov AE, 1996. Distinct effects of heat shock and ATP depletion on distribution and isoform patterns of human hsp27 in endothelial cells. FEBS Letters 392: 100-104.
28. Lutsch G, Vetter R. Offhaus U, Wieske M, Grone HJ, Klemenz R, Schimke I, Stahl J, Benndorf R, 1997. Abundance and localization of the small heat shock proteins hsp25 and α B-crystallin in rat and human heart. Circulation 96: 3466-3476.
29. Martin J, Mestril R, Hilal-Dandan R, Brunton LL, Dillmann WH, 1997. Small heat shock proteins and protection against ischemic injury in cardiac myocytes. Circulation 96: 4343-4348.
30. Maulik N, Watanabe M, Zu Y-O, Huang C-K, Cordis GA, Schley JA, Das DK, 1996. Ischemic preconditioning triggers the activation of MAP kinases and MAPKAP kinase 2 in rat hearts. FEBS Letters 396: 233-237.
31. Mirkes P, Little S, Cornel L, Welsh M, Laney T, Wright F, 1996. Induction of heat shock protein 27 in rat embryos exposed to hyperthermia. Mol Repro Develop 45: 276-284.
32. Nagarkatti DS, Sha'afi RI, 1988. Role of p38 MAP kinase in myocardial stress. J Mol Cell Cardiol 30: 1651-1664.
33. Pelech SL, Meier KE, Krebs EG, 1986. Rapid microassay for protein kinase C translocation in Swiss 3T3 cells. Biochemistry 25: 8348-8353.
34. Ping P, Zhang J, Cao X, Qiu Y, Tang XL, Clerk A, Sugden P, 1998. Activation of the p38 MAPK and the p46/p54 JNKs after brief episodes of ischemia/reperfusion in the heart of conscious rabbit. J Mol Cell Cardiol 30: A263.
35. Trammell BW, Pain S, Downey JM, Cohen MV and Critz SD, 1998. MAPKAPK2 is activated in preconditioned rabbit heart. J Mol Cell Cardiol 30: A265.
36. Vander Heide RS, Ganote CE, 1987. Increased myocyte fragility following anoxic injury. J Mol Cell Cardiol 19: 1085-1103.
37. Vander Heide RS, Rim D, Hohl CM, Ganote CE, 1990. An in vitro model of myocardial ischemia utilizing isolated adult rat myocytes. J Mol Cell Cardiol 22: 165-181.
38. Weinbrenner C, Liu G-S, Cohen MV, Downey JM, 1997. Phosphorylation of tyrosine 182 of p38 mitogen-activated protein kinase correlates with the protection of preconditioning in the rabbit heart. J Mol Cell Cardiol 29: 2383-2391.
39. Ytrehus K, Liu Y, Downey JM, 1994. Preconditioning protects ischemic rabbit heart by protein kinase C activation. Am J Physiol 266: (Heart Circ Physiol 35) H1145-H1152.
40. Young PR, McLaughlin MM, Kumar S, Kassis S, Doyle ML, McNulty D, Gallagher TF, Fisher S, McDonnell PC, Carr SA, Huddleston MJ, Seibel G, Porter TG, Livi GP, Adams JL, and Lee JC, 1997. Pyridinyl imidazole inhibitors of p38 mitogen activated protein kinase bind in the ATP site. J Biol Chem 272: 12116-12121.
41. Zu Y-L, Ai Y, Gilchrist A, Maulik N, Watras J, Sha'afi RI, Das DK, Huang C-K, 1997. High expression and activation of MAP kinase-activated protein kinase 2 in cardiac muscle cells. J Mol Cell Cardiol 29: 2159-2168.