Activation of mitogen activated protein kinases in in vivo ischemia/reperfused myocardium in rats

Journal of Molecular and Cellular Cardiology

Volumn 31, Issue 6, 1999, Pages 1269-1279

  Omura, Takashi ^a   Yoshiyama, Minoru ^a   Shimada, Takehiro ^a   Shimizu, Naruhito ^a   Kim, Shokei ^a   Iwao, Hiroshi ^a   Takeuchi, Kazuhide ^a   Yoshikawa, Junichi ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Activator protein 1 (AP 1); c Jun NH2 terminal kinase (JNK); DNA fragmentation; Extra cellular signal regulated kinase (ERK); Ischemia reperfusion; Mitogen activated protein kinase (MAPK); Myocardial ischemia

Indexed keywords

DNA FRAGMENT; MITOGEN ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1;

AGAR GEL ELECTROPHORESIS; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CORONARY REPERFUSION; DNA BINDING; ELECTROPHORETIC MOBILITY; ENZYME ACTIVATION; HEART MUSCLE ISCHEMIA; IMMUNOBLOTTING; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

EID: 0033153001     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.1999.0959     Document Type: Article

References (33)

1. Aikawa R, Komuro I, Yamazaki T, Zou Y, Kudoh S, Tanaka M, Shiojima I, Hiroi Y and Yazaki Y, 1997. Oxidative stress activates extracellular signal-regulated kinases through Src and Ras in cultured cardiac myocytes of neonatal rats. J Clin Invest 100: 1813-1821.
2. Bogoyevitch MA, Gillespie-Brown J, Ketterman AJ, Fuller SJ, Ben-Levy R, Ashworth A, Marshall CJ and Sugden PH, 1996. Stimulation of the stress-activated mitogen-activated protein kinase subfamilies in perfused heart. p38/RK mitogen-activated protein kinases and c-Jun N-terminal kinases are activated by ischemia/reperfusion. Circ Res 79: 162-173.
3. Brand T, Sharma HS, Fleischmann KE, Duncker DJ, McFalls EO, Verdouw PD and Schaper W, 1992. Proto-oncogene expression in porcine myocardium subjected to ischemia and reperfusion. Circ Res 71: 1351-1360.
4. Cano E and Mahadevan LC, 1995. Parallel signal processing among mammalian MAPKs. Trends Biochem Sci 20: 117-122.
5. Das DK, Engelman RM and Kimura Y, 1993. Molecular adaptation of cellular defences following preconditioning of the heart by repeated ischaemia. Cardiovasc Res 27: 578-584.
6. Davis RJ, 1994. MAPKs: New JNK expands the group. Trends in Biochemical Sciences 19: 470-473.
7. Derijard B, Hibi M, Wu IH, Barrett T, Su B, Deng T, Karin M and Davis RJ, 1994. JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell 76: 1025-1037.
8. Entman ML and Smith CW, 1994. Postreperfusion inflammation: A model for reaction to injury in cardiovascular disease. Cardiovasc Res 28: 1301-1311.
9. Fishbein MC, Maclean D and Maroko PR, 1978. Experimental myocardial infarction in the rat: Qualitative and quantitative changes during pathologic evolution. Am J Pathol 90: 57-70.
10. Fliss H and Gattinger D, 1996. Apoptosis in ischemic and reperfused rat myocardium. Circ Res 79: 949-956.
11. Force T, Pombo CM, Avruch JA, Bonventre JV and Kyriakis JM, 1996. Stress-activated protein kinases in cardiovascular disease. Circ Res 78: 947-953.
12. Gay RG, 1990. Early and late effects of captopril treatment after large myocardial infarction in rats. J Am Coll Cardiol 16: 967-977.
13. Gotoh Y, Nishida E, Yamashita T, Hoshi M, Kawakami M and Sakai H, 1990. Microtubule-associated-protein (MAP) kinase activated by nerve growth factor and epidermal growth factor in PC12 cells. Identify with the mitogen-activated MAP kinase of fibroblastic cells. Eur J Biochem 193: 661-669.
14. Han J, Lee JD, Bibbs L and Ulevitch RJ, 1994. A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. Science 265: 808-811.
15. Hearse DJ, Maxwell L, Saldanha C and Gavin JB, 1993. The myocardial vasculature during ischemia and reperfusion: A target for injury and protection. J Mol Cell Cardiol 25: 759-800.
16. Hibi M, Lin A, Smeal T, Minden A and Karin M, 1993. Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain. Genes Dev 7: 2135-2148.
17. Huwiler A, Stabel S, Fabbro D and Pfeilschifter J, 1995. Platelet-derived growth factor and angiotensin II stimulate the mitogen-activated protein kinase cascade in renal mesangial cells: Comparison of hypertrophic and hyperplastic agonists. Biochem J 305: 777-784.
18. Jeroudi MO, Hartley CJ and Bolli R, 1994. Myocardial reperfusion injury: Role of oxygen radicals and potential therapy with antioxidants. Am J Cardiol 73: 2B-7B.
19. Kameshita I and Fujisawa H, 1989. A sensitive method for the detection of calmodulin-dependent protein kinase II activity in sodium dodecyl sulfate-polyacrylamide gel. Anal Biochem 183: 139-143.
20. Karin M, 1995. The regulation of AP-1 activity by mitogen-activated protein kinases. J Biol Chem 270: 16483-16486.
21. Kim S, Izumi Y, Yano M, Hamaguchi A, Miura K, Yamanaka S, Miyazaki H and Iwao H, 1998. Angiotensin blockade inhibits activation of mitogen-activated protein kinases in rat balloon-injured artery. Circulation 97: 1731-1737.
22. Kloner RA, Przyklenk K and Whittaker P, 1989. Deleterious effects of oxygen radicals in ischemia/reperfusion. Resolved and unresolved issues. Circulation 80: 1115-1127.
23. Kyriakis JM, Banerjee P, Nikolakaki E, Dai T, Rubie EA, Ahmad MF, Avruch J and Woodgett JR, 1994. The stress-activated protein kinase subfamily of c-Jun kinases. Nature 369: 156-160.
24. Lee W, Mitchell P and Tjian R, 1987. Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements. Cell 49: 741-752.
25. Marshall CJ, 1995. Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation. Cell 80: 179-185.
26. Raingeaud J, Gupta S, Rogers JS, Dickens M, Han J, Ulevitch RJ and Davis RJ, 1995. Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine. J Biol Chem 270: 7420-7426.
27. Schreiber E, Matthias P, Müller MM and Schaffner W, 1989. Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells. Nucleic Acids Res 17: 6419.
28. Seko Y, Tobe K, Ueki K, Kadowaki T and Yazaki Y, 1996. Hypoxia and hypoxia/reoxygenation activate Raf-1, mitogen-activated protein kinase kinase, mitogen-activated protein kinases, and S6 kinase in cultured rat cardiac myocytes. Circ Res 78: 82-90.
29. Shimizu N, Yoshiyama M, Omura T, Hanatani A, Kim S, Takeuchi K, Iwao H and Yoshikawa J, 1998. Activation of mitogen-activated protein kinases and activator protein-1 in myocardial infarction in rats. Cardiovasc Res 38: 116-124.
30. Weisman HF, Bush DE, Mannisi JA and Bulkley BH, 1985. Global cardiac remodeling after acute myocardial infarction: A study in the rat model. J Am Coll Cardiol 5: 1355-1362.
31. Xia Z, Dickens M, Raingeaud J, Davis RJ and Greenberg ME, 1995. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 270: 1326-1331.
32. Yano M, Kim S, Izumi Y, Yamanaka S and Iwao H, 1998. Differential activation of cardiac c-jun aminoterminal kinase and extracellular signal-regulated kinase in angiotensin II-mediated hypertension. Circ Res 83: 752-760.
33. Yin T, Sandhu G, Wolfgang CD, Burrier A, Webb RL, Rigel DF, Hai T and Whelan J, 1977. Tissue-specific pattern of stress kinase activation in ischemic/reperfused heart and kidney. J Biol Chem 272: 19943-19950.