Interactions of Immunoglobulins Outside the Antigen-Combining Site

Advances in Immunology

Volumn 82, Issue , 2004, Pages 155-215

  Nezlin, Roald ^a   Ghetie, Victor ^b  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANAPHYLATOXIN; CD4 ANTIGEN; CLUSTERIN; COMPLEMENT COMPONENT C1Q; COMPLEMENT COMPONENT C3B; COMPLEMENT COMPONENT C4B; FC RECEPTOR; FIBRONECTIN; GALACTOSYLTRANSFERASE; GALECTIN 1; GALECTIN 3; GLYCOPROTEIN; HISTIDINE RICH GLYCOPROTEIN; IMMUNOGLOBULIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN BINDING FACTOR; IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2; IMMUNOGLOBULIN G2B; IMMUNOGLOBULIN G3; IMMUNOGLOBULIN G4; IMMUNOGLOBULIN M; JACALIN; MANNOSE BINDING PROTEIN; PROLACTIN; RHEUMATOID FACTOR; STAPHYLOCOCCUS PROTEIN A; UNCLASSIFIED DRUG; UNINDEXED DRUG;

AMINO ACID COMPOSITION; ANTIBODY COMBINING SITE; BINDING AFFINITY; BINDING SITE; COMPLEMENT ACTIVATION; COMPLEMENT FIXATION; CONFORMATION; GENE MUTATION; IMMUNE RESPONSE; LIGAND BINDING; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN DOMAIN; REVIEW; TRANSCYTOSIS;

EID: 1142286441     PISSN: 00652776     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0065-2776(04)82004-2     Document Type: Article

References (270)

1. Achari, A., Hale, S. P., Howard, A. J., Clore, M. G., Gronenborn, A. M., Hardman, K. D., and Whitlow, M. (1992). 1.67 Å X-ray structure of the B2 immunoglobulin-binding domain of streptococcal protein G and comparison to the NMR structure of B1 domain. Biochemistry 31, 10449-10457.
2. Åckerström, B., and Björck, L. (1986). A physicochemical study of protein G, a molecule with unique immunoglobulin-binding properties. J. Biol. Chem. 261, 10240-10247.
3. Åckerström, B., Nielsen, E., and Björck, L. (1987). Definition of IgG- and albumin-binding regions of streptococcal protein G. J. Biol. Chem. 262, 13388-13391.
4. Åckerström, B., Lindquist, A., Maelen, C. V., Grubb, A., Lindahl, G., and Vaerman, J.-P. (1994). Interaction between streptococcal protein Arp and different molecular forms of human immunoglobulin A. Mol. Immunol. 31, 393-400.
5. Andrieux, C., Pires, R., Moreau, M.-C., and Bouvet, J.-P. (1998). Release of the soluble co-receptor (protein Fv) of secretory immunoglobulins after colonization of axenic rats by the human gut microflora. Scand. J. Immunol. 48, 192-195.
6. Antón, L. C., Ruiz, S., Barrio, E., Marques, G., Sánchez, A., and Vivanco, F. (1994). C3 binds with similar efficiency to Fab and Fc regions of IgG immune aggregates. Eur. J. Immunol. 24, 599-604.
7. Antonsson, A., and Johansson, P. J. (2001). Binding of human and animal immunoglobulins to the IgG receptor induced by human cytomegalovirus. J. Gen. Virol. 82, 1137-1145.
8. Armour, K. L., Atherton, A., Williamson, L. M., and Clark, M. R. (2002). The contrasting IgG-binding interactions of human and herpes simplex virus Fc receptors. Biochem. Soc. Transact. 30, 495-499.
9. Artandi, S. E., Canfield, S. M., Tao, M.-H., Calame, K. L., Morrison, S. L., and Bonagura, V. R. (1991). Molecular analysis of IgM rheumatoid factor binding chimeric IgG. J. Immunol. 146, 603-610.
10. Arya, S., Chen, F., Spycher, S., Isenman, D. E., Shulman, M. J., and Painter, R. H. (1994). Mapping of amino acid residues in the Cμ3 domain of mouse IgM important in macromolecular assembly and complement-dependent cytolysis. J. Immunol. 152, 1206-1212.
11. Atherton, A., Armour, K. L., Bell, S., Minson, A. C., and Clark, M. R. (2000). The herpes simplex virus type 1 receptor discriminates between IgG1 allotypes. Eur. J. Immunol. 30, 2540-2547.
12. Baird, B., Zheng, Y., and Holowka, D. (1993). Structural mapping of IgE-FcεRI, an immunoreceptor complex. Acc. Chem. Res. 26, 428-434.
13. Bakos, M. A., Kurosky, A., and Goldblum, R. M. (1991). Characterization of a critical binding site of human polymeric Ig on secretory component. J. Immunol. 147, 3419-3426.
14. Bakos, M. A., Widen, S. G., and Goldblum, R. M. (1994). Expression and purification of biologically active domain I of the human polymeric immunoglobulin receptor. Mol. Immunol. 31, 165-171.
15. Barclay, A. N., Brown, M. H., Law, S. K. A., McKnight, A. J., Tomlinson, M. G., and van der Merwe, P. A. (1997). "The Leucocyte Antigen Facts Book," 2nd ed. Academic Press, London.
16. 2-mediated neutralization of C3a and C5a anaphylatoxins: A novel effector function of immunoglobulins. Nat. Med. 9, 431-438.
17. Belson, A., Yorgin, P. D., Al-Uzri, A.-Y., Salvatierra, O., Higgins, J., and Alexander, S. R. (2001). Long-term plasmaphoresis and protein A column treatment of recurrent FSGS. Pediatr Nephrol. 16, 985-989.
18. H3 gene products: Natural ligands for HIV gp120. Science 261, 1588-1591.
19. Björck, L., and Kronval, G. (1981). Purification and some properties of streptococcal protein G. A novel IgG-binding reagent. J. Immunol. 133, 969-974.
20. Bonagura, V. R., Artandi, S. E., Agostino, N., Tao, M.-H., and Morrison, S. L. (1992). Mapping rheumatoid factor binding sites using genetically engineered chimeric IgG antibody. DNA Cell Biol. 11, 245-252.
21. Bonagura, V. R., Artandi, S. E., Davidson, A., Randen, I., Agostino, N., Thompson, K., Natvig, J. B., and Morrison, S. L. (1993). Mapping studies reveal unique epitopes on IgG recognized by rheumatoid arthritis derived monoclonal rheumatoid factors. J. Immunol. 151, 3840-3852.
22. Borvak, J., Richardson, J., Medesan, C., Antohe, F., Radu, C., Simionescu, M., Ghetie, V., and Ward, E. S. (1998). Functional expression of the MHC class I-related receptor, FcRn in endothelial cells of mice. Int. Immunol. 10, 1289-1298.
23. Bouvet, J.-P., Pirès, R., and Quan, C. P. (1996). Protein Fv (Fv fragment binding protein): A mucosal human superantigen reacting with normal immunoglobulins. In "Human B Cell Superantigens" (M. Zouali, Ed.), pp. 179-188. R. C. Landes Co., Austin, TX.
24. Boyle, M. D. P. (1990). Bacterial Immunoglobulin-binding Proteins. Academic Press, San Diego.
25. Bradl, H., Wittmann, J., Milius, D., Vettermann, C., and Jäck, H.-M. (2003). Interaction of murine precursor B cell receptor with stroma cells is controlled by the unique tail of λ5 and stroma cell-associated heparan sulfate. J. Immunol. 171, 2338-2348.
26. Brady, R. L., and Barclay, A. N. (1996). The structure of CD4. In "The CD4 Molecule" (D. R. Littman, Ed.), pp. 1-18. Springer-Verlag, Berlin.
27. Braisted, A. C., and Wells, J. A. (1996). Minimizing a binding domain from protein A. Proc. Natl. Acad. Sci. USA 93, 5688-5692.
28. Braun, N., and Riesler, T. (1999). Immunoadsorption as a tool for the immunomodulation of humoral and cellular immune system in autoimmune diseases. Ther. Apheresis 3, 240-245.
29. Braun, N., Erley, C., Klein, R., Koffler, I., Saal, J., and Riesler, T. (2000). Immunoadsorption onto protein A induced remission in severe systemic lupus erithematosus. Nephrol. Dial. Transplant. 15, 1367-1372.
30. Bray, B. A., Osman, M., and Turino, G. M. (1994). Evidence that fibronectin-immunoglobulin complexes occur normally in plasma. Proc. Soc. Exp. Biol. Med. 207, 324-331.
31. Brüggemann, M., Teale, C., Clark, M., Bindon, C., and Waldmann, H. (1989). A matched set of rat/mouse chimeric antibodies. Identification and biological properties of rat H chain constant regions μ, γ1, γ2a, γ2b, γ2c, ε, and α. J. Immunol. 142, 3145-3150.
32. Burmeister, W. P., Gastinel, L. N., Simister, N. E., Blum, M. L., and Bjorkman, P. J. (1994a). Crystal structure at 2.2 Å resolution of the MHC-related neonatal Fc receptor. Nature 372, 336-343.
33. Burmeister, W. P., Huber, A. H., and Bjorkman, P. J. (1994b). Crystal structure of the complex of rat neonatal Fc receptor with Fc. Nature 372, 379-383.
34. H2 domain and is modulated by the hinge region. J. Exp. Med. 173, 1483-1491.
35. Cedergren, L., Andersson, R., Jansson, B., Uhlen, M., and Nilsson, B. (1993). Mutational analysis of the interaction between staphylococcal protein A and human IgG. Protein Eng. 6, 441-448.
36. Chapman, T. L., You, I., Joseph, I. M., Bjorkman, P. J., Morrison, S. L., and Raghavan, M. (1999). Characterization of the interaction between the herpes simplex virus type I Fc receptor and immunoglobulin G. J. Biol. Chem. 274, 6911-6919.
37. Chen, P. P., and Carson, D. A. (1994). New insight on the physiological and pathological rheumatoid factors in humans. In "Autoimmunity: Physiology and Disease" (A. Cutinho and M. Kazatchkine, Eds.), pp. 247-268. Wiley, New York.
38. Christianson, G. J., Brooks, W., Vekasi, S., Manolfi, E. A., Wiles, J., Roopenian, S. L., Rothlein, R., and Roopenian, D. C. (1997). β2-microglobuhn-deficient mice are protected from hypergammaglobulinemia and have defective antibody response because of the increased catabolism. J. Immunol. 159, 4781-4792.
39. Cianga, P., Medesan, C., Richardson, J. A., Ghetie, V., and Ward, E. S. (1999). Identification and function of neonatal Fc receptor in mammary gland of lactating mice. Eur. J. Immunol. 29, 2515-2523.
40. Coloma, M. J., Clift, A., Wims, L., and Morrison, S. L. (2000). The role of carbohydrate in the assembly and function of polymeric IgG. Mol. Immunol. 37, 1081-1090.
41. Corper, A. L., Sohi, M. K., Bonagura, V. R., Steinitz, M., Jefferis, R., Feinstein, A., Beale, D., Taussig, M. J., and Sutton, B. J. (1997). Structure of human IgM rheumatoid factor Fab bound to its autoantigen IgGFc reveals a novel topology of antibody-antigen interaction. Nat. Struct. Biol. 4, 374-381.
42. Corthesy, B. (2002). Recombinant immunoglobulin A: Powerful tools for fundamental and applied research. Trends Biotechnol. 20, 65-71.
43. Coyne, R. S., Siebrecht, M., Peitsch, M. C., and Casanova, J. E. (1994). Mutational analysis of polymeric immunoglobulin receptor/ligand interactions. Evidence for the involvement of multiple complementary determining region (CDR)-like loops. J. Biol. Chem. 269, 31620-31625.
44. 2: A positive implication for mucosal defense. J. Immunol. 161, 879-888.
45. Crottet, P., and Corthesy, B. (1999). Mapping the interaction between immune IgA and murine secretory component carrying epitope binding to IgA. J. Biol. Chem. 274, 31456-31462.
46. Dall'Acqua, W. F., Woods, R. M., Ward, E. S., Palaszynski, S. R., Patel, N. K., Brewah, Y. A., Wu, H., Kiener, P. A., and Langermann, S. (2002). Increasing affinity of a human IgG1 for the neonatal Fc receptor: Biological consequences. J. Immunol. 169, 5171-5180.
47. Deisenhofer, J. (1981). Crystallographic refinement and atomic models of human Fc fragment and its complex with fragment B of protein A from Staphylococcus aureus at 2.9 and 2.8 Å resolution. Biochemistry 20, 2361-2370.
48. DeLano, W. L., Ultsch, M. H., deVos, A. M., and Wells, J. A. (2000). Convergent solution to binding at a protein-protein interface. Science 287, 1279-1283.
49. Delespesse, G., Sarfati, M., Wu, C. Y., Fournier, S., and Letellier, M. (1992). The low-affinity receptor for IgE. Immunol. Rev. 125, 77-97.
50. Derrick, J. P., and Wigley, D. B. (1994). The third IgG-binding domain from streptococcal protein G. An analysis by X-ray crystallography of the structure alone and in complex with Fab. J. Mol. Biol. 243, 906-918.
51. Dima, S., Medesan, C., Mota, G., Moraru, I., Sjöquist, J., and Ghetie, V. (1984). Effect of protein A and its fragment B on the catabolism and Fc receptor sites of IgG. Eur. J. Immunol. 13, 605-614.
52. Dong, X., Storkus, W. J., and Salter, R. D. (1999). Binding and uptake of agalactosyl IgG by mannose receptor on macrophages and dendritic cells. J. Immunol. 163, 5427-5434.
53. Dubin, G., Socolof, E., Frank, I., and Friedman, H. M. (1991). Herpes simplex virus type 1 Fc receptor protects infected cells from antibody-dependent cellular cytotoxicity. J. Virol. 65, 7046-7050.
54. Dubin, G., Basu, S., Mallory, D. L., Basu, M., Tal-Singer, R., and Friedman, H. M. (1994). Characterization of domains of herpes simplex virus type 1 glycoprotein E involved in Fc binding activity for IgG aggregates. J. Virol. 68, 2478-2486.
55. Dudich, E. I., and Dudich, I. V. (1983). Polarization fluorescence, spin label and ultracentrifugal studies of specific interaction of low molecular weight proteins with the Fc fragment of human immunoglobulin G. Mol. Immunol. 20, 1267-1272.
56. Dudich, E. I., Nezlin, R., and Franěk, F. (1978). Fluorescence polarization analysis of various immunoglobulins. Dependence of rotational relaxation time on protein concentration and on ability to precipitate with antigen. FEBS Lett. 89, 89-92.
57. Duncan, A. R., and Winter, G. (1988). The binding site for C1q on IgG. Nature 332, 738-740.
58. Edmundson, A. B., Guddat, L. W., Rosauer, R. A., Andersen, K. W., Shan, L., and Fan, Z-C. (1995). Three-dimensional aspects of IgG structure and function. In "The Antibodies" (M. Zanetti and J. D. Capra, Eds.), Vol. I, pp. 41-100. Harwood Academic Publ., Luxembourg.
59. Epstein, J., Eichbaum, Q., Sheriff, S., and Esekovitz, R. A. B. (1996). The collectins in innate immunity. Curr. Opin. Immunol. 8, 29-35.
60. Esnault, V. L. M., Besnier, D., Testa, A., Coville, P., Simon, P., Subra, J.-P., and Andrain, M. A. P. (1999). Effect of protein A immunoadsorption in nephrotic syndrome of various etiologies. J. Am. Soc. Nephrol. 10, 2014-2017.
61. Fallgreen-Gebauer, E., Gebauer, W., Bastian, A., Kratzin, H. D., Eiffert, H., Zimmermann, B., Kavas, M., and Hilschmann, N. (1993). The covalent linkage of secretory component to IgA. Structure of sIgA. Biol. Chem. Hoppe Seyler 375, 1023-1028.
62. Fassina, G. (2000). Protein A mimetic (PAM) affinity purification. In "Methods in Molecular Biology" (P. Bailon, G. K. Ehrlich, W.-J. Fung, and W. Berthold, Eds.), Vol. 147, pp. 57-68. Humana Press, Totowa, NJ.
63. Fassina, G., Verdoliva, A., Odlerna, M. R., and Cassini, G. (1996). Protein A mimetic peptide ligand for affinity purification of antibodies. J. Mol. Recog. 9, 564-569.
64. Favorell, H. W., Nauwynck, H. J., van Oostveldt, P., Mettenleiter, T. C., and Pensaert, M. B. (1997). Antibody-induced and cytoskeleton-mediated redistribution and shedding of viral glycoproteins, expressed on pseudorabies virus-infected cells. J. Virol. 71, 8554-8561.
65. Felson, D. T., Lavalley, M. P., Baldassare, A. R., Block, J. A., Caldwell, J. R., Cannon, G. W., Deal, C., Evans, S., Fleischmann, R., Gendreau, R. M., Harvis, E. R., Matteson, E. L., Roth, S. H., Schumacher, R., Weisman, M. H., and Furst, D. E. (1999). The Prosorba column for treatment of refractory rheumatoid arthritis. Arthritis Rheum. 42, 2153-2159.
66. Firan, M., Bawdon, R., Radu, C., Ober, R. J., Eaken, D., Antohe, F., Ghetie, V., and Ward, E. S. (2001). The MHC class I related receptor FcRn plays an essential role in the maternofetal transfer of gamma-globulin in humans. Int. Immunol. 13, 993-1002.
67. Forsgren, A., Ghetie, V., Lindmark, R., and Sjöquist, J. (1983). Protein A and its exploitation. In "Staphylococcal and Streptococcal Infections" (C. S. F. Eastmon and C. Adlam, Eds.), Vol. I, pp. 429-480. Academic Press, New York.
68. Forsgren, A., Brant, M., Möllenkvist, A., Muyombwe, A., Janson, H., Woin, N., and Riesbeck, K. (2001). Isolation and characterization of a novel IgD-binding protein from Moraxella catarrhalis. J. Immunol. 167, 2112-2120.
69. Frick, I.-M., Wikstrom, M., Forsen, S., Drakenberg, T., Gomi, H., Sjobring, V., and Björck, L. (1992). Convergent evolution among immunoglobulin-binding bacterial proteins. Proc. Natl. Acad. Sci. USA 89, 8532-8536.
70. Frick, I.-M., Åkesson, P., Cooney, J., Sjöbring, U., Sjijbring, U., Schmidt, K.-H., Gomi, H., Hattori, S., Tagawa, C., Kishimoto, F., and Björck, L. (1994). Protein H-a surface protein of Streptococcus pyogenes with separate binding sites for IgG and albumin. Mol. Microbiol. 12, 143-151.
71. Frick, I.-M., Crossin, K. L., Edelman, G. M., and Björck, L. (1995). Protein H a bacterial surface protein with affinity for both immunoglobulin and fibronectin type III domains. EMBO J. 14, 1674-1679.
72. Frutiger, S., Hughes, G. J., Hanly, W. C., Kingzette, M., and Jaton, J. C. (1986). The amino-terminal domain of rabbit secretory component is responsible for the noncovalent binding to immunoglobulin A dimers. J. Biol. Chem. 261, 16673-16681.
73. Gallagher, T., Alexander, P., Bryan, P., and Gilliland, G. L. (1994). Two crystal structure of the B1 immunoglobulin-binding domain of streptococcal protein G and comparison with NMR. Biochemistry 33, 4721-4729.
74. Garman, S. C., Kinet, J.-P., and Jardetzky, T. S. (1998). Crystal structure of the human high-affinity IgE receptor. Cell 95, 951-961.
75. Garman, S. C., Wurzburg, B. A., Tarchevskaya, S. S., Kinet, J.-P., and Jardetzky, T. S. (2000). Structure of the Fc fragment of human IgE bound to its high-affinity receptor FcεRIα. Nature 406, 259-266.
76. Garman, S. C., Sechl, S., Kinet, J.-P., and Jardetzky, T. S. (2001). The analysis of the human affinity IgE receptor FcεRIα from multiple crystal forms. J. Mol. Biol. 311, 1049-1062.
77. Gauthier, L., Rossi, B., Roux, E, Termine, E., and Schiff, C. (2002). Galectin-1 is a stromal cell ligand of the pre-B cell receptor (BCR) implicated in synapse formation between pre-B and stromal cells in pre-BCR triggering. Proc. Natl. Acad. Sci. USA 99, 13014-13019.
78. Genovese, A., Bouvet, J.-P., Florio, G., Lamparter-Schummert, B., Björck, L., and Marone, G. (2000). Bacterial immunoglobulin superantigen proteins A and L activate human heart mast cells by interacting with immunoglobulin E. Immun. Infect. 68, 5517-5524.
79. + cells through interaction with the κ light chains of IgE. J. Immunol. 170, 1854-1861.
80. Ghetie, V., and Sjöquist, J. (1984a). Use of protein A in the detection and quantitation of immunoglobulin G on the surface of lymphocytes. Methods Enzymol. 108, 405-413.
81. Ghetie, V., and Sjöquist, J. (1984b). Separation of cells by affinity chromatography on protein A gels. Methods Enzymol. 108, 132-138.
82. Ghetie, V., and Ward, E. S. (2000). Multiple roles for the major histocompatibility complex class I-related receptor. Annu. Rev. Immunol. 18, 739-766.
83. Ghetie, V., Hubbard, J. G., Kim, J.-K., Tsen, M.-F., Lee, Y., and Ward, E. S. (1996). Abnormally short serum half-lives of IgG in beta 2-microglobulin deficient mice. Eur. J. Immunol. 26, 690-696.
84. Ghetie, V., Popov, S., Borvak, J., Radu, C., Matesoi, D., Medesan, C., Ober, R., and Ward, E. S. (1997). Serum persistence of an IgG fragment by random mutagenesis. Nat. Biotechnol. 15, 637-640.
85. Ghetie, V., Ward, E. S., and Vitetta, E. S. (2004). The pharmacokinetics of antibody and immunotoxins in mice and humans. In "Pharmacokinetics and Pharamacodynamics of Anti-Cancer Agents" (W. D. Figg and H. McLeod, Eds.). Humana Press, Totawa, NJ (in press).
86. Gorgani, N. N., Parish, C. R., Easterbrook-Smith, S. B., and Altin, J. G. (1997). Histidine-rich glycoprotein binds to human IgG and C1q and inhibits the formation of insoluble immune complexes. Biochemistry 36, 6653-6662.
87. Gorgani, N. N., Parish, C. R., and Altin, J. G. (1999a). Differential binding of histidine-rich glycoprotein (HRG) to human IgG subclasses and IgG molecules containing kappa and lambda light chains. J. Biol. Chem. 274, 29633-29640.
88. Gorgani, N. N., Altin, J. G., and Parish, C. R. (1999b). Histidine-rich glycoprotein prevents the formation of insoluble immune complexes by rheumatoid factor. Immunology 98, 456-463.
89. Gorgani, N. N., Altin, J. G., and Parish, C. R. (1999c). Histidine-rich glycoprotein regulates the binding of monomeric IgG and immune complexes to monocytes. Int. Immunol. 11, 1275-1282.
90. Gould, H. J., Sutton, B. J., Beavil, A. J., Beavil, R. J., McCloskey, N., Coker, H. A., Fear, D., and Smurthwaite, L. (2003). The biology of IgE and the basis of allergic disease. Annu. Rev. Immunol. 21, 579-628.
91. Graille, M., Stura, E. A., Corper, A. L., Sutton, B. J., Taussig, M. J., Charbonnier, J.-B., and Silverman, G. J. (2000). Crystal structure of a Staphylococcus aureus protein A domain complexed with the Fab fragment of a human IgG antibody. Structural basis for recognition of B-cell receptors and superantigen activity. Proc. Natl. Acad. Sci. USA 97, 5399-5404.
92. Graille, M., Stura, E. A., Housden, N. G., Beckingham, J. A., Bottomley, S. P., Beale, D., Taussig, M. J., Sutton, B. J., Gore, M. G., and Charbonnier, J.-B. (2001). Complex between Peptostreptococcus magnus protein L and a human antibody reveals structural convergence in the interaction modes of Fab binding proteins. Structure 9, 679-687.
93. Graille, M., Harrison, S., Crump, M. P., Findlow, S. C., Housden, N. G., Muller, B. H., Batail-Poirot, N., Sibaï, G., Sutton, B. J., Taussig, M. J., Jolivet-Reynaud, C., Gore, M. G., and Stura, E. A. (2002). Evidence for plasticity and structural mimicry at the immunoglobulin light chain-protein L interface. J. Biol. Chem. 277, 47500-47506.
94. Guddat, L. W., Herron, J. N., and Edmundson, A. B. (1993). Three-dimensional structure of human immunoglobulin with hinge deletion. Proc. Natl. Acad. Sci. USA 90, 4271-4275.
95. Guthrie, T. H., and Oral, A. (1989). Immune trombocytopenia purpura: A pilot study of staphylococcal protein A immunomodulation in refractory patients. Semin. Hematol. 26, 3-9.
96. Hanson, D. C., and Schumaker, V. N. (1984). A model for the formation and interconversion of protein A-IgG soluble complexes. J. Immunol. 132, 1397-1409.
97. Harris, L. J., Larson, S. B., Hasel, K. W., and McPherson, A. (1997). Refined structure of an intact IgG2a monoclonal antibody. Biochemistry 36, 1581-1597.
98. Harrison, P. T., and Allen, J. M. (1998). High affinity IgG binding to FcγRI (CD64) is modulated by two distinct IgSF domains and the transmembrane domain of the receptor. Protein Eng. 11, 225-232.
99. Hashim, O. H., Ng, C. L., Gedeh, G. S., and Jaafar, M. I. N. (1991). IgA binding lectins isolated from distinct Artocarpus species demonstrate differential specificity. Mol. Immunol. 28, 393-398.
100. Hashim, O. H., Ahmad, F., and Shuib, A. S. (2001). The application of Artocarpus integer seed lectin-M in the detection and isolation of selective human serum acute-phase proteins and immunoglobulins. Immunol. Commun. 30, 131-141.
101. Hashimoto, T., Takishita, M., Kosaka, M., Sano, T., and Matsumoto, T. (2001). Superantigens and autoantigens may be involved in the pathogens of gastric mucosa-associated lymphoid tissue lymphoma. Int. J. Hematol. 74, 197-204.
102. 2 subclasses from normal human serum using protein G and jackfruit lectin (jacalin) affinity chromatography. Immunol. Lett. 22, 273-280.
103. Hedén, L.-O., Frithz, E., and Lindahl, G. (1991). Molecular characterization of an IgA receptor from group B streptococci: Sequence of the gene, identification of a proline-rich region with unique structure and isolation of N-terminal fragments with IgA-binding capacity. Eur. J. Immunol. 21, 1481-1490.
104. Herr, A. B., Ballister, E. R., and Bjorkman, P. J. (2003). Insights into IgA-mediated immune responses from the crystal structures of human FcαRI and its complex with IgA1-Fc. Nature 423, 614-620.
105. α3 domain motif directs polymeric Ig receptor-mediated secretion. J. Exp. Med. 189, 747-751.
106. Hogarth, P. M. (2002). Fc receptors are major mediators of antibody-based inflammation in autoimmunity. Curr. Opin. Immunol. 14, 798-802.
107. Holmskov, U., Malhotra, R., Sim, R. B., and Jensenius, J. C. (1994). Collectins: Collagenous C-type lectins of the innate immune defense system. Immunol. Today 15, 67-74.
108. Hugly, T. E. (1984). Structure and function of the anaphylatoxins. Springer Semin. Immunopathol. 7, 193-219.
109. Hugly, T. E., and Müller-Eberhard, H. J. (1978). Anaphylatoxins: C3a and C5a. Adv. Immunol. 26, 1-53.
110. Hulett, M. D., and Hogarth, P. M. (1994). Molecular basis of Fc receptor function. Adv. Immunol. 57, 1-127.
111. Hulett, M. D., and Hogarth, P. M. (1998). The second and third extracellular domains of FcγRI (CD64) confer the unique high affinity binding of IgG2a. Mol. Immunol. 35, 989-996.
112. Hulett, M. D., Witort, E., Brinkworth, R. I., McKenzie, I. F., and Hogarth, P. M. (1994). Identification of the IgG binding site of the human low affinity receptor for IgG Fc gamma RII. Enhancement and ablation of binding by site-directed mutagenesis. J. Biol. Chem. 270, 21188-21194.
113. Idusogie, E. E., Presta, L. G., Gazzano-Santoro, H., Totpal, K., Wong, P. Y., Ultsch, M., Meng, Y. G., and Mulkerrin, M. G. (2000). Mapping of the C1q binding site on Rutixan, a chimeric antibody with human IgG1 Fc. J. Immunol. 164, 4178-4184.
114. Inganas, M. (1981). Comparison of mechanism of interaction between protein A from Staphylococcus aureus and human monoclonal IgG, IgA and IgM in relation with classical Fc and alternative F(ab′)2-protein A interaction. Scand J. Immunol. 13, 343-352.
115. Inganas, M., Johansson, S. G. O., and Bennich, H. H. (1980). Interaction of human polyclonal IgE and IgG from different species with protein A from Staphylococcus aureus: Demonstration of protein A-reactive sites located in the F(ab′)2 fragment of human IgG. Scand. J. Immunol. 12, 23-31.
116. Israel, E. J., Patel, V. K., Taylor, S. F., Marshak-Rothstein, A., and Simister, N. E. (1995). Requirement for β2-microglobulin-associated Fc receptor for acquisition of maternal IgG by fetal and neonatal mice. J. Immunol. 154, 6246-6251.
117. Israel, E. J., Wilsker, D. F., Hayes, K. C., Schonfeld, D., and Simister, N. E. (1996). Increased clearance of IgG in mice that lack beta 2-microglobulin: possible protective role of FcRn. Immunology 89, 573-578.
118. Jefferis, R., and Lund, J. (2002). Interaction sites on human IgG-Fc for FcγR: Current models. Immunol. Lett. 82, 57-65.
119. Johansson, P. J. H., Nardella, F. A., Sjöquist, J., Schryder, A. K., and Christensen, P. (1988). Herpes simplex type 1-induced Fc receptor binds to the Cγ2-Cγ3 interface region of IgG in the area that binds staphylococcal protein A. Immunology 66, 8-18.
120. Johansson, P. J. H., Otam, T., Tsuchiya, N., Malone, C. C., and Williams, R. C. (1994). Studies of protein A and herpes simplex virus-1 induced Fcγ-binding specificities. Different binding patterns for IgG3 from Caucasian and Oriental subjects. Immunology 83, 631-638.
121. Jones, S. E., and Jomary, C. (2002). Clusterin. Intern. J. Biochem. Cell. Biol. 34, 427-431.
122. Junghans, R. P., and Anderson, C. L. (1996). The protection receptor of IgG catabolism is the beta-2-microglobulin containing neonatal intestinal transport receptor. Proc. Natl. Acad. Sci. USA 93, 5512-5516.
123. Kabir, S. (1998). Jacalin: A jackfruit (Artocarpus heterophylus) seed-derived lectin of versatile applications in immunobiological research. Immunol. Methods 212, 193-211.
124. Kabir, S. (2002). Immunoglobulin purification by affinity chromatography using protein A mimetic ligands prepared by combinatorial chemical synthesis. Immunol. Invest. 31, 263-278.
125. Kabir, S., Ahmed, I. S. A., and Daar, A. S. (1995). The binding of jacalin with rabbit immunoglobulin G. Immunol. Invest. 24, 725-735.
126. Kacskovics, I., Wu, Z., Simister, N. E., Frenyo, L. V., and Hammarstrom, L. (2000). Cloning and characterization of bovine MHC class I-like Fc receptor. J. Immunol. 164, 1889-1897.
127. Karray, S., Joumpan, L., Maroun, R. C., Isenberg, D., Silverman, G. J., and Zouali, M. (1998). Structural basis of the gp120 superantigen-binding site on human immunoglobulins. J. Immunol. 161, 6681-6688.
128. 13C NMR study of the mode of interaction in solution of the B fragment of staphylococcal protein A and the Fc fragments of mouse immunoglobulin G. FEBS Lett. 328, 49-54.
129. Kato, K., Sautes-Fridman, C., Yamada, W., Kobayashi, K., Uchiyama, S., Kim, H., Enokizono, J., Galinha, A., Kobayashi, Y., Fridman, W. H., Arata, Y., and Shimada, I. (2000a). Structural basis of the interaction between IgG and Fcγ receptors. J. Mol. Biol. 295, 213-224.
130. Kato, K., Fridman, W. H., Arata, Y., and Sautes-Fridman, C. (2000b). A conformational change in the Fc precludes the binding of two Fcγ receptor molecules to one IgG. Immunol. Today 21, 310-313.
131. Kilmon, M. A., Ghirlando, R., Strub, M.-P. Beavil, R. L., Gould, H. J., and Conrad, D. H. (2001). Regulation of IgE production requires oligomerization of CD23. J. Immunol. 167, 3139-3145.
132. Kim, J.-K., Tsen, M.-F., Ghetie, V., and Ward, E. S. (1994a). Identifying amino acid residues that influence plasma clearance of murine IgG1 fragments by site-directed mutagenesis. Eur J. Immunol. 24, 542-548.
133. Kim, J.-K., Tsen, M.-F., Ghetie, V., and Ward, E. S. (1994b). Localization of the site of the murine IgG1 molecule that is involved in binding to the murine intestinal Fc receptor. Eur. J. Immunol. 24, 2429-2434.
134. Kim, J.-K., Tsen, M.-F., Ghetie, V., and Ward, E. S. (1994c). Catabolism of the murine IgG1 molecule: Evidence that both CH2-CH3 domain interfaces are required for persistence of IgG1 in the circulation of mice. Scand. J. Immunol. 40, 457-465.
135. Kim, J.-K., Tsen, M.-F., Ghetie, V., and Ward, E. S. (1995). Evidence that the hinge region plays a role in maintaining serum levels of the murine IgG1 molecule. Mol. Immunol. 32, 467-475.
136. Kim, J.-K., Firan, M., Radu, C. G., Kim, C.-H., Ghetie, V., and Ward, E. S. (1999). Mapping the site of human IgG for binding of the MHC class I-related receptor FcRn. Eur. J. Immunol. 29, 2819-2825.
137. Kishore, U., and Reid, K. B. M. (1999). Modular organization of proteins containing C1q-like globular domain. Immunopharmacology 42, 15-21.
138. Koppel, R., and Solomon, B. (2001). IgM detection via selective recognition by mannose-binding protein. J. Biochem. Biophys. Methods 49, 641-647.
139. Krook, M., Mosbach, K., and Ramström, O. (1998). Novel peptides binding to the Fc-portion of immunoglobulins obtained from a combinatorial phage display peptide library. J. Immunol. Methods 221, 151-157.
140. Kuehn, M. J., Ogg, D. J., Kihlberg, J., Slonim, L. N., Flemmer, K., Bergfors, T., and Hultgren, S. J. (1993). Structural basis of pilus recognition by the PapD chaperone. Science 262, 1234-1241.
141. Lakins, J. N., Poon, S., Easterbrook-Smith, S. B., Carver, J. A., Tenniswood, M. P. R., and Wilson, M. R. (2002). Evidence that clusterin has discrete chaperone and ligand binding sites. Biochemistry 41, 282-291.
142. Langone, J. J., Boyle, M. D. P., and Borsos, T. (1978). Studies on the interaction between protein A and immunoglobulin G. II. Composition and activity of complexes formed between protein A and IgG. J. Immunol. 121, 333-341.
143. Law, S. K. A., and Dodds, A. W. (1997). The internal thioester and the covalent binding properties of the complement proteins C3 and C4. Protein Sci. 6, 263-274.
144. Leadbetter, E. A., Rifkin, I. R., Hohlbaum, A. M., Beaudette, B. C., Shlomchik, M. J., and Marshak-Rothstein, A. (2002). Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors. Nature 416, 603-607.
145. Lenert, P., Kroon, D., Spiegelberg, H., Golub, E. S., and Zanetti, M. (1990). Human CD4 binds immunoglobulins. Science 248, 1639-1643.
146. Lenert, P., Lenert, G., and Zanetti, M. (1995). Human recombinant CD4 and CD4-derived synthetic peptides agglutinate immunoglobulin-coated latex particles. Evidence that residues 25-28 and 35-38 of human CD4 form two separate immunoglobulin binding sites. Mol. Immunol. 32, 1399-1404.
147. Levinson, A. I. (1989). Nature and stimulus for rheumatoid factor production. In "Autoantibodies to Immunoglobulins" (F. Shakib, Ed.), pp. 130-150. Karger, Basel, Switzerland.
148. Li, R., Dowd, V., Stewart, D. J., Burton, S. J., and Lowe, C. R. (1998). Design, synthesis, and application of protein A mimetic. Nat. Biotechnol. 16, 190-195.
149. Lian, L.-Y., Derrick, J. P., Sutcliffe, M. J., Yang, J. C., and Roberts, G. C. K. (1992). Determination of the solution structure of domain II and III of protein G from Streptococcus by 1H nuclear magnetic resonance. J. Mol. Biol. 228, 1219-1234.
150. Lian, L.-Y., Barsukov, I. L., Derrick, J. P., and Roberts, G. C. K. (1994). Mapping the interactions between streptococcal protein G and the Fab fragment of IgG in solution. Nat. Struct. Biol. 1, 355-357.
151. Litwin, V., Jackson, W., and Grose, C. (1992). Receptor properties of two varicella-zoster virus glycoproteins, gpI and gpIV, homologous to herpes simplex virus gE and gI. J. Virol. 66, 3643-3651.
152. Liu, F.-T. (1990). Molecular biology of IgE-binding protein, IgE-binding factors and IgE receptors. Crit. Rev. Immunol. 10, 289-306.
153. Liu, F.-T. (1993). S-type mammalian lectins in allergic inflammation. Immunol. Today 14, 486-490.
154. Liu, Z., Roopenian, D. C., Zhou, X., Christianson, G. J., Diaz, L. A., Sedmark, D. D., and Anderson, C. L. (1997). β2-microglobulin-deficient mice are resistant to bullous pemphigoid. J. Exp. Med. 186, 777-783.
155. 2: Separation of affinity from specificity. Mol. Immunol. 30, 1279-1285.
156. Lo Conte, L., Chothia, C., and Janin, J. (1999). The atomic structure of protein-protein recognition sites. J. Mol. Biol. 285, 2177-2196.
157. Malhotra, R., Wormald, M. R., Rudd, P. M., Fischer, P. B., Dwek, R. A., and Sim, R. B. (1995). Glycosylation changes of IgG associated with rheumatoid arthritis can activate complement via the mannose-binding protein. Nat. Med. 1, 237-243.
158. Marino, M., Ruvo, M., Defalco, S., and Fassina, G. (2000). Prevention of systemic lupus erithematosus in MRL/1pr mice by administration of an immunoglobulin-binding peptide. Nat. Biotechnol. 18, 735-739.
159. Martin, W. L., and Bjorkman, P. J. (1999). Characterization of the 2:1 complex between the class I MHC-related Fc receptor and its Fc ligand in solution. Biochemistry 38, 12639-12647.
160. Martin, W. L., West, A. P., Gau, L., and Bjorkman, P. J. (2001). Crystal structure at 2.8 Å of an FcRn/heterodimeric Fc complex: Mechanism of pH-dependent binding. Mol. Cell 7, 867-877.
161. Masson, P. L. (1993). Elimination of infectious agents and increase of IgG catabolism as possible modes of action of IVIG. J. Autoimmun. 6, 683-689.
162. Matsumoto, H., Ho, S., Miyazaki, T., and Ohta, T. (1983). Structural
163. Maxwell, K. F., Powell, M. S., Hulett, M. D., Barton, P. A., McKenzie, F. C., Garrett, T. P. J., and Hogarth, P. M. (1999). Crystal structure of the human leukocyte Fc receptor, FcRIIa. Nat. Struct. Biol. 6, 437-442.
164. Medesan, C., Radu, C., Kim, J.-K., Ghetie, V., and Ward, E. S. (1996). Localization of the site of IgG molecule that regulates maternofetal transmission in mice. Eur. J. Immunol. 26, 2533-2536.
165. Medesan, C., Matesoi, D., Radu, C., Ghetie, V., and Ward, E. S. (1997). Delineation of the amino acid residues involved in the transcytosis and catabolism of mouse IgG1. J. Immunol. 158, 2211-2217.
166. Medesan, C., Cianga, P., Mummert, M., Stanescu, D., Ghetie, V., and Ward, E. S. (1998). Comparative studies of rat IgG to further delineate the Fc:FcRn interaction site. Eur. J. Immunol. 28, 2092-2100.
167. Meininger, D. P., Rance, M., Starovasnik, M. A., Fairbrother, W. J., and Skelton, N. J. (2000). Characterization of the binding interface between E-domain of staphylococcal protein A and an antibody Fv-fragment. Biochemistry 39, 26-36.
168. Messerschmidt, G. L., Henry, H. W., Snyder, H. W., Bertram, J., Mittelman, A., Ainsworth, S., Fiore, J., Viola, M. V., Louise, J., Ambinder, E., MacKintosh, F. R., Higby, D. J., O'Brien, P., Kiprov, D., Hamburger, M., Balint, J. P., Fisher, L. D., Perkins, W., Pinsky, C. M., and Jones, F. R. (1989). Protein A immunotherapy in the treatment of cancer: An update. Semin. Hematol. 26, 19-24.
169. Metzger, H. (2002). Molecular versatility of antibodies. Immunol. Rev. 185, 186-205.
170. Mihaescu, S., Sulica, A., Sjoquist, J., and Ghetie, V. (1979). Affinity of rabbit IgG antibody complexed with protein A of S. aureus. Rev. Roum. Biochim. 16, 57-60.
171. Miletic, V. D., and Frank, M. M. (1995). Complement-immunoglobulin interactions. Curr. Opin. Immunol. 7, 41-47.
172. Moks, J., Abrahmsen, L., Nilsson, B., Hellman, U., Sjoquist, J., and Uhlen, M. (1986). Staphylococcal protein A consists of five IgG-binding domains. Eur. J. Biochem. 156, 637-643.
173. Monteiro, R. C., and van de Winkel, J. C. J. (2003). IgA Fc receptors. Annu. Rev. Immunol. 21, 177-204.
174. H2 domain of chimeric human IgG1 anti-HLA-DR is necessary for C1q, FcγRI and FcγRIII binding. Immunology 86, 319-324.
175. Mota, G., Ghetie, V., and Sjöquist, J. (1978). Characterization of the soluble complex formed by reacting rabbit IgG with protein A of Staphylococcus aureus. Immunochemistry 15, 639-642.
176. H1 domain of IgG is not essential for C3 covalent binding: Importance of the other constant domains as targets for C3. Int. Immunol. 10, 97-106.
177. Muñoz, E., Vidarte, L., Pastor, C., Casado, M., and Vivanco, F. (1998b). A small domain (6.5 kDa) of bacterial protein G inhibits covalent binding to the Fc region of IgG immune complexes. Eur. J. Immunol. 28, 2591-2597.
178. Muroi, K., Sasaki, R., and Miura, Y. (1989). The effect of immunoadsorption therapy by a protein A column on patients with trombocytopenia. Semin. Hematol. 25, 10-14.
179. Nagashunmugam, T., Lubinski, J., Wang, L., Goldstein, L. T., Weeks, B. S., Sundaresan, P., Kang, E. H., Dubin, G., and Friedman, H. M. (1998). In vivo immune evasion mediated by the herpes simplex type 1 IgG Fc receptor. J. Virol. 72, 5351-5359.
180. Nardella, F. A., Teller, D. C., and Mannik, M. (1981). Studies on the antigenic determinants of self-association of IgG rheumatoid factor. J. Exp. Med. 154, 112-125.
181. Nevens, J. R., Mallia, A. K., Wendt, M. W., and Smith, F. K. (1992). Affinity chromatographic purification of immunoglobulin M antibodies utilizing immobilized mannan-binding protein. J. Chromatogr. 597, 247-256.
182. Newkirk, M. (1996). Fc glycosylation and rheumatoid factors. In "Abnormalities of IgG Glycosylation and Immunological Disorders" (D. A. Isenberg and T. W. Rademacher, Eds.), pp. 119-130. Wiley, London.
183. Nezlin, R. (1990). Internal movements in immunoglobulin molecules. Adv. Immunol. 40, 1-40.
184. Nezlin, R. (1993). Detection of the C3a complement component in commercial gamma globulins by dot blotting. J. Immunol. Methods 163, 269-272.
185. Nezlin, R. (1998). "The Immunoglobulins. Structure and Function." Academic Press, San Diego.
186. Nezlin, R. (2000). A quantitative approach to the determination of antigen in immune complexes. J. Immunol. Methods 237, 1-17.
187. Nezlin, R., and Freywald, A. (1992). Complexes of IgG molecules and C3a and C4a complement components in human serum. Eur. J. Immunol. 22, 1955-1957.
188. Nezlin, R., Freywald, A., and Oppermann, M. (1993). Proteins separated from human IgG molecules. Mol. Immunol. 30, 935-940.
189. Nilson, B., Moks, T., Jansson, B., Abrahamsen, L., Elmblad, A., Holmgren, E., Henrichson, C., Jones, T. A., and Uhlen, M. (1987). A synthetic IgG-binding domain based on staphylococcal protein A. Protein Eng. 1, 107-113.
190. Nilson, B. H. K., Solomon, A., Björck, L., and Åkerström, B. (1992). Protein L from Peptostreptococcus magnus binds to the κ light chain variable domain. J. Biol. Chem. 267, 2234-2239.
191. Nilson, B. H. K., Frick, I.-M., Åkesson, P., Forsén, S., Björck, L., Åkerström, B., and Wikström, M. (1995). Structure and stability of protein H and the M1 protein from Streptococcus pyogenes. Implications for other surface proteins of gram-positive bacteria. Biochemistry 34, 13688-13698.
192. Nissim, A., Schwarzbaum, S., Siraganian, R., and Eshhar, Z. (1993). Fine specificity of the IgE interaction with the low and high affinity Fc receptor. J. Immunol. 150, 1365-1374.
193. Norderhaug, I. N., Johansen, F.-E., Schjerven, H., and Brandzaeg, P. (1999). Regulation of the formation and external transport of secretory immunoglobulins. Crit. Rev. Immunol. 19, 481-508.
194. Ober, R. J., Radu, C., Ghetie, V., and Ward, E. S. (2001). Differences in promiscuity for antibody-FcRn interaction across species: Implications for therapeutic antibodies. Int. Immunol. 13, 1551-1559.
195. Ohno, T., Kubagawa, H., Sanders, S. K., and Cooper, M. D. (1990). Biochemical nature of an Fcμ receptor on human B-lineage cells. J. Exp. Med. 172, 1165-1175.
196. Oppliger, I. R., Nardella, F. A., Stone, G. C., and Mannik, M. (1987). Human rheumatoid factors bear the internal image of the Fc binding region of Staphylococcal protein A. J. Exp. Med. 166, 702-710.
197. Patella, V., Giuliano, A., Bouvet, J.-P., and Marone, G. (1998). Endogenous superallergen protein Fv induces IL-4 secretion from human FcεRI cells through interaction with the VH3 region of IgE. J. Immunol. 161, 5647-5655.
198. Perkins, S. J., Nealis, A. S., Sutton, B. J., and Feinstein, A. (1991). Solution structure of human and mouse IgM by synchrotron X-ray scattering and molecular graphics modeling. A possible mechanism for complement binding. J. Mol. Biol. 221, 1345-1366.
199. Phalipon, A., Cardona, A., Kraehenbuhl, J.-P., Edelman, L., Sansonette, P., J., and Corthesy, B. (2002). Secretory component: A new role in secretory IgA-mediated immune exclusion in vivo. Immunity 17, 107-115.
200. Pleass, R. J., Areschoug, T., Lindahl, G., and Woof, J. M. (1999). Streptococcal IgA-binding proteins bind in the Cα2-Cα3 interdomain region and inhibit binding of IgA to human CD89. J. Biol. Chem. 276, 8197-8204.
201. Pleass, R. J., Dunlop, J. J., Anderson, C. M., and Woof, J. M. (2001). Identification of residues in the CH2/CH3 domain interface of IgA essential for interaction with the human Fcα receptor (FcαR) CD89. J. Biol. Chem. 274, 23508-23514.
202. Popov, S., Hubbard, J. G., Kim, J.-K., Ober, B., Ghetie, V., and Ward, E. S. (1996). The stoichiometry and affinity of the interaction of murine Fc fragments with the MHC class I-related receptor, FcRn. Mol. Immunol. 33, 521-530.
203. Potter, K. N., Li, Y., and Capra, J. D. (1996). Staphylococcal protein A simultaneously interact with framework region 1, complementarity-determining region 2 and framework region 3 on human VH3-encoded Igs. J. Immunol. 157, 2982-2988.
204. Praetor, A., Jones, R. M., Wong, W. L., and Hunziker, W. (2002). Membrane-anchored human FcRn can obgomerize in the absence of IgG. J. Mol. Biol. 321, 277-284.
205. Rabinovich, G. A., Baum, L. G., Tinari, N., Paganelli, R., Natoli, C., Liu, F.-T., and Iacobelli, S. (2002). Galectins and their ligands: Amplifiers, silencers or tuners of the inflammatory response? Trends Immunol. 23, 313-320.
206. Radaev, S., and Sun, P. D. (2001). Recognition of immunoglobulins by Fcγ receptors. Mol. Immunol. 38, 1073-1083.
207. Radaev, S., Motyka, S., Fridman, W. H., Sautes-Fridman, C., and Sun, P. D. (2001). The structure of a human type III Fcγ receptor in complex with Fc. J. Biol. Chem. 276, 16469-16477.
208. Raghavan, M., and Bjorkman, P. J. (1996). Fc receptors and their interactions with immunoglobulins. Annu. Rev. Cell Dev. Biol. 12, 181-220.
209. Raghavan, M., Chen, M. Y., Gastinel, L. N., and Bjorkman, P. J. (1994). Investigation of the interaction between class I MHC-related Fc receptor and its immunoglobulin G ligand. Immunity 1, 303-315.
210. Ravetch, J. V., and Bolland, S. (2001). IgG Fc receptors. Annu. Rev. Immunol. 19, 275-290.
211. Reid, K. B. M. (1996). The complement system. In "Molecular Immunology" (B. D. Hames and D. M. Glover, Eds.), pp. 326-381. IRL Press, Oxford, UK.
212. Roben, P. W., Salem, A. N., and Silverman, G. J. (1995). VH3 family antibodies bind domain D of staphylococcal protein A. J. Immunol. 154, 6437-6445.
213. Robertson, M. W., and Liu, F.-T. (1991). Heterogeneous IgE glycoforms characterized by differential recognition of an endogenous lectin (IgE-binding protein). J. Immunol. 147, 3024-3030.
214. Romagnani, S., Giudizi, M. G., delPrete, E., Maggi, R., Biagiotti, F., Almerigogna, F., and Ricci, M. (1982). Demonstration on protein A of two district immunoglobulin-binding sites and their role in the mitogenic activity of Staphylococcus aureus Cowan-1 on human B cells. J. Immunol. 129, 596-602.
215. Roopenian, D. C., Christanson, G. J., Sproule, T. J., Brown, A. C., Akilesh, S., Jung, N., Petkova, S., Avanessian, L., Choi, E. Y., Shaffer, D. J., Eden, P. A., and Anderson, C. L. (2003). The MHC class I-like IgG receptor controls perinatal IgG transport, IgG homeostasis, and late of IgG-Fc-coupled drugs. J. Immunol. 170, 3528-3533.
216. Rostagno, A., Frangione, B., and Gold, L. I. (1991). Biochemical studies of the interaction of fibronectin with Ig. J. Immunol. 146, 2687-2693.
217. Rostagno, A., Williams, M., Frangione, B., and Gold, L. I. (1996). Biochemical analysis of the interaction of fibronectin with IgG and localization of the respective binding sites. Mol. Immunol. 33, 561-572.
218. Rostagno, A. A., Gallo, G., and Gold, L. I. (2002). Binding of polymeric IgG to fibronectin in extracellular matrices: An in vitro paradigm for immune-complex deposition. Mol. Immunol. 38, 1101-1111.
219. Ruffet, E., Pirès, R., Pillot, J., and Bouvet, J.-P. (1994). Activation of the classical pathway of complement by non-immune complexes of immunoglobulins with human protein Fv (Fv fragment-binding protein). Scand. J. Immunol. 40, 359-362.
220. Sanchez, L. M., Penny, D. M., and Bjorkman, P. J. (1999). Stoichiometry of the interaction between the MHC-related Fc receptor and its Fc ligand. Biochemistry 38, 9471-9476.
221. Sandin, C., Linse, S., Areschoug, T., Woof, J. M., Reinholdt, J., and Lindahl, G. (2002). Isolation and detection of human IgA using a streptococcal IgA-binding peptide. J. Immunol. 169, 1357-1364.
222. H3 subgroup. J. Immunol. 147, 1877-1883.
223. Sauer-Eriksson, A. E., Keywegt, G. J., Uhlen, M., and Jones, T. A. (1995). Crystal structure of the C2 fragment of streptococcal protein G in complex with the Fc domain of human IgG. Structure 3, 265-278.
224. Schuck, R., Radu, C., and Ward, E. S. (1999). Sedimentation equilibrium analysis of recombinant mouse FcRn with murine IgG1. Mol. Immunol. 36, 1117-1125.
225. Seegan, G. W., Smith, C. A., and Schumacher, V. N. (1979). Changes in the quaternary structure of IgG upon reduction of the interheavy-chain disulfide bonds. Proc. Natl. Acad. Sci. USA 76,907-911.
226. H2 influence the relative abilities of IgG2 and IgG3 to activate complement. Mol. Immunol. 34, 1019-1029.
227. H families S107 or J666 bind to protein A. J. Immunol. 145, 2989-2993.
228. Sharon, N., and Lis, H. (2003). "Lectins." Kluwer Academic Publishers, Dordrecht, The Netherlands.
229. Shibuya, A., Sakamoto, N., Shimizu, Y., Shibuya, K., Osawa, M., Hiroyama, T., Eyre, H. J., Sutherland, G. R., Endo, Y., Fujita, Y., Miyabayashi, T., Sakano, S., Tsuji, T., Nakayama, E., Phillips, J. H., Lanier, L. L., and Nakauchi, H. (2000). Fcα/μ receptor mediates endocytosis of IgM coated microbes. Nat. Med. 1, 441-446.
230. Shields, R. L., Namenuk, A. K., Hong, K., Meng, G., Rae, J., Briggs, J., Xie, D., Lai, J., Stadlen, A., Li, B., Fox, J. A., and Presta, L. G. (2001). High resolution mapping of the binding site of human IgG1 for FeγRI, FeγRII, FcγRIII and FeRn and design of the IgG1 variants with improved binding to FeγR. J. Biol. Chem. 276, 6591-6604.
231. 1 heavy chain. J. Biol. Chem. 268, 5866-5871.
232. Silverman, G. J. (1997). B-cell superantigens. Immunol. Today 18, 379-386.
233. Silverman, G. J., Pirès, R., and Bouvet, J.-P. (1996). An endogenous sialoprotein and a bacterial B cell superantigen compete in their VH family-specific binding interactions with human Igs. J. Immunol. 157, 4496-4502.
234. Simister, N. E. (1998). Multiple roles of FcRn. In "The Immunoglobulin Receptors and Their Physiological and Pathological Roles in Immunology" (J. G. J. Van de Winkel and P. M. Hogarth, Eds.), pp. 63-71. Kluwer Academic Publishers, London.
235. Simister, N. E., and Mostov, K. E. (1989). An Fc receptor structurally related to MHC class I antigen. Nature 337, 184-187.
236. Sjobring, U., Björck, L., and Kastern, W. (1991). Streptococcal protein G. Gene structure and protein-binding properties. J. Biol. Chem. 266, 399-405.
237. R columns. Semin. Hematol. 26, 31-41.
238. Sondermann, P., Huber, R., and Jacob, U. (1999). Crystal structure of the soluble form of the human Fcγ-receptor IIb: A new member of the immunoglobulin superfamily at 1.7 Å resolution. EMBO J. 18, 1095-1103.
239. Sondermann, P., Huber, R., Oosthuizen, V., and Jacob, U. (2000). The 3.2-Å crystal structure of the human IgG1 Fc fragment-FcγRIII complex. Nature 406, 267-273.
240. Stenberg, L., O'Toole, P. W., Mestecky, J., and Lindahl, G. (1994). Molecular characterization of protein Sir, a streptococcal cell surface protein that binds both immunoglobulin A and immunoglobulin G. J. Biol. Chem. 269, 13458-13464.
241. Sutton, B., Corper, A., Bonagura, V. R., and Taussig, M. (2000). The structure and origin of rheumatoid factor. Immunol. Today 21, 177-180.
242. Takai, T. (2002). Roles of the Fc receptors in autoimmunity. Nat. Rev. Immunol. 2, 580-592.
243. Tamm, A., and Schmidt, R. E. (1997). IgG binding sites on human Fc gamma receptors. Int. Rev. Immunol. 16, 57-85.
244. Tao, M.-H., Smith, R. I. F., and Morrison, S. L. (1993). Structural features of human immunoglobulin G that determine isotype-specific differences in complement activation. J. Exp. Med. 178, 661-667.
245. Tashiro, M., and Montelione, G. T. (1995). Structures of bacterial immunoglobulin-binding domains and their complexes with immunoglobulin. Curr. Opin. Struct. Biol. 5, 471-481.
246. H2 domain is crucial for antibody dependent complement activation. Mol. Immunol. 37, 995-1004.
247. Tomana, M., Zikan, J., Kulhavy, R., Bennett, J. C., and Mestecky, J. (1993a). Interactions of galactosyltransferase with serum and secretory immunoglobulins and their component chains. Mol. Immunol. 30, 277-286.
248. Tomana, M., Zikan, J., Moldoveanu, Z., Kulhavy, R., Bennett, J. C., and Mestecky, J. (1993b). Interactions of cell-surface galactosyltransferase with immunoglobulins. Mol. Immunol. 30, 265-275.
249. Tsuchiya, N., Williams, R. C., and Hatt-Flechter, L. M. (1990). Rheumatoid factors may be the internal image of Fc-binding protein of herpes simplex virus type I. J. Immunol. 144, 4742-4748.
250. Turner, H., and Kinet, J.-P. (1999). Signalling through the high-affinity IgE receptor FcεRI. Nature 402, 24-30.
251. Vaerman, J. P., Langendries, A., Giffroy, D. A., Brandzaeg, P., and Kobayashi, K. (1998). Lack of SC/pIgR-mediated epithelial transport of a human polymeric IgA devoid of J chain: In vitro and in vivo studies. Immunology 95, 90-96.
252. Van Vliet, K. E., De Graaf-Miltenburg, L. A. M., Verhoef, J., and Van Strijp, J. A. G. (1992). Direct evidence for antibody bipolar bridging on herpes simplex virus-infected cells. Immunology 77, 109-115.
253. Vaughn, D. E., Milburn, C. M., Penny, D. M., Martin, W. L., Johnson, J. L., and Bjorkman, P. J. (1997). Identification of critical IgG binding epitopes on the neonatal Fc receptor. J. Mol. Biol. 274, 597-607.
254. Vivanco, F., Muñoz, E., Vidarte, L., and Pastor, C. (1999). The covalent interaction of C3 with IgG immune complexes. Mol. Immunol. 36, 843-852.
255. Walker, A. M., Montgomery, D. W., Saraiya, S., Ho, T. W. C., Garewal, H. S., Wilson, J., and Lorand, L. (1995). Prolactin-immunoglobulin G complexes from human serum act as costimulatory ligands causing proliferation of malignant B lymphocytes. Proc. Natl. Acad. Sci. USA 92, 3278-3282.
256. Wan, T., Beavil, R. L., Fabiane, S. M., Beavil, A. J., Sohi, M. K., Keown, M., Young, R. J., Henry, A. J., Owens, R. J., Gould, H. J., and Sutton, B. J. (2002). The crystal structure of IgE Fc reveals an asymmetrical bent conformation. Nature 3, 681-686.
257. Ward, E. S., Zhou, J., Ghetie, V., and Ober, R. J. (2003). Evidence to support the cellular mechanism involved in serum IgG homeostasis in humans. Int. Immunol. 15, 1-9.
258. West, A. P., and Bjorkman, P. J. (2000). Crystal structure and immunoglobulin G binding properties of the human major histocompatibility complex related Fc receptor. Biochemistry 39, 9698-9708.
259. Wikström, M., Drakenberg, T., Forsén, S., Sjöbring, U., and Björck, L. (1994). Three-dimensional solution structure of an immunoglobulin light chain-binding domain of protein L. Comparison with the IgG-binding domains of protein G. Biochemistry 33, 14011-14017.
260. Wikström, M., Sjöbring, U., Drakenberg, T., Forsén, S., and Björck, L. (1995). Mapping of the immunoglobulin light chain-binding site of protein L. J. Mol. Biol. 250, 128-133.
261. Wilson, M. R., and Easterbrook-Smith, S. B. (1992). Clusterin binds by a multivalent mechanism to the Fc and Fab regions of IgG. Biochim. Biophys. Acta 1159, 319-326.
262. Wilson, M. R., Roeth, P. J., and Easterbrook-Smith, S. B. (1991). Clusterin enhances the formation of insoluble immune complexes. Biochem. Biophys. Res. Commun. 177, 985-990.
263. Wines, B. D., Sardjono, C. T., Trist, H. M., Lay, C.-S., and Hogarth, P. M. (2001). The interaction of FcαRI with IgA and its implications for ligand binding by immunoreceptors of the leukocyte receptor cluster. J. Immunol. 166, 1781-1789.
264. H2-associated carbohydrate structure on the functional properties and in vivo fate of chimeric mouse-human immunoglobulin G1. J. Exp. Med. 180, 1087-1096.
265. Wright, J. F., Shulman, M. J., Isenman, D. E., and Painter, R. H. (1990). C1 binding by mouse IgM. The effect of abnormal glycosylation at position 402 resulting from a serine to asparagine exchange at residue 406 of the μ chain. J. Biol. Chem. 265, 10506-10513.
266. Wurzburg, B. A., and Jardetzky, T. S. (2001). Structural insights into the interactions between human IgE and its high affinity receptor FeεRI. Mol. Immunol. 38, 1063-1072.
267. Youngblood, K., Fruchter, L., Ding, G., Lopez, J., Bonagura, V., and Davidson, A. (1994). Rheumatoid factors from the peripheral blood of two patients with rheumatoid arthritis are genetically heterogeneous and somatically mutated. J. Clin. Invest. 93, 852-861.
268. Yu, Z., and Lennon, V. A. (1999). Mechanism of intravenous immune globulin therapy in antibody-mediated diseases. N. Engl. J. Med. 340, 227-128.
269. Zhang, Y., Boesen, C. C., Radaev, S., Brooks, A. G., Fridman, W. H., Sautes-Fridman, C., and Sun, P. D. (2000). Crystal structure of the extracellular domain of a human FeγRIII. Immunity 13, 387-395.
270. Zuckier, L. S., Chang, C. J., Scharff, M. D., and Morrison, S. L. (1998). Chimeric human-mouse IgG antibodies with shuffled constant region exons demonstrate that multiple domains contribute to in vivo half-life. Cancer Res. 58, 3905-3908.