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Volumn 15, Issue 2, 2003, Pages 187-195

Evidence to support the cellular mechanism involved in serum IgG homeostasis in humans

Author keywords

FcRn; Human IgG1; Immunodeficiency; Lysosomal trafficking; Serum persistence

Indexed keywords

FC RECEPTOR; IMMUNOGLOBULIN G;

EID: 0037325779     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/dxg018     Document Type: Article
Times cited : (176)

References (45)
  • 1
    • 0000146003 scopus 로고
    • A theoretical model of γ-globulin catabolism
    • Brambell, F. W. R., Hemmings, W. A. and Morris, I. G. 1964. A theoretical model of γ-globulin catabolism. Nature 203:1352.
    • (1964) Nature , vol.203 , pp. 1352
    • Brambell, F.W.R.1    Hemmings, W.A.2    Morris, I.G.3
  • 2
    • 0029927482 scopus 로고    scopus 로고
    • Abnormally short serum half-lives of IgG in beta 2-microglobulin-deficient mice
    • Ghetie, V., Hubbard, J. G., Kim, J. K., Tsen, M. F., Lee, Y. and Ward, E. S. 1996. Abnormally short serum half-lives of IgG in beta 2-microglobulin-deficient mice. Eur. J. Immunol. 26:690.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 690
    • Ghetie, V.1    Hubbard, J.G.2    Kim, J.K.3    Tsen, M.F.4    Lee, Y.5    Ward, E.S.6
  • 3
    • 0029891262 scopus 로고    scopus 로고
    • The protection receptor for IgG catabolism is the beta2-microglobulin-containing neonatal intestinal transport receptor
    • Junghans, R. P. and Anderson, C. L. 1996. The protection receptor for IgG catabolism is the beta2-microglobulin-containing neonatal intestinal transport receptor. Proc. Natl Acad. Sci. USA 93:5512.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 5512
    • Junghans, R.P.1    Anderson, C.L.2
  • 4
    • 0029856774 scopus 로고    scopus 로고
    • Increased clearance of IgG in mice that lack beta 2-microglobulin: Possible protective role of FcRn
    • Israel, E. J., Wilsker, D. F., Hayes, K. C., Schoenfeld, D. and Simister, N. E. 1996. Increased clearance of IgG in mice that lack beta 2-microglobulin: possible protective role of FcRn. Immunology 89:573.
    • (1996) Immunology , vol.89 , pp. 573
    • Israel, E.J.1    Wilsker, D.F.2    Hayes, K.C.3    Schoenfeld, D.4    Simister, N.E.5
  • 6
    • 0021825396 scopus 로고
    • Isolation and characterization of an Fc receptor from neonatal rat small intestine
    • Simister, N. E. and Rees, A. R. 1985. Isolation and characterization of an Fc receptor from neonatal rat small intestine. Eur. J. Immunol. 15:733.
    • (1985) Eur. J. Immunol. , vol.15 , pp. 733
    • Simister, N.E.1    Rees, A.R.2
  • 8
    • 0028980061 scopus 로고
    • Requirement for a beta 2-microglobulin-associated Fc receptor for acquisition of maternal IgG by fetal and neonatal mice
    • Israel, E. J., Patel, V. K., Taylor, S. F., Marshak-Rothstein, A. and Simister, N. E. 1995. Requirement for a beta 2-microglobulin-associated Fc receptor for acquisition of maternal IgG by fetal and neonatal mice. J. Immunol. 154:6246.
    • (1995) J. Immunol. , vol.154 , pp. 6246
    • Israel, E.J.1    Patel, V.K.2    Taylor, S.F.3    Marshak-Rothstein, A.4    Simister, N.E.5
  • 10
    • 0031449358 scopus 로고    scopus 로고
    • FcRn: The MHC Class I-related receptor that is more than an IgG transporter
    • Ghetie, V. and Ward, E. S. 1997. FcRn: the MHC Class I-related receptor that is more than an IgG transporter. Int. Immunol. 18:592.
    • (1997) Int. Immunol. , vol.18 , pp. 592
    • Ghetie, V.1    Ward, E.S.2
  • 11
    • 0034042660 scopus 로고    scopus 로고
    • Multiple roles for the major histocompatibility complex class I-related receptor FcRn
    • Ghetie, V. and Ward, E. S. 2000. Multiple roles for the major histocompatibility complex class I-related receptor FcRn. Annu. Rev. Immunol. 18:739.
    • (2000) Annu. Rev. Immunol. , vol.18 , pp. 739
    • Ghetie, V.1    Ward, E.S.2
  • 12
    • 0028061347 scopus 로고
    • A major histocompatibility complex class I-like Fc receptor cloned from human placenta: Possible role in transfer of immunoglobulin G from mother to fetus
    • Story, C. M., Mikulska, J. E. and Simister, N. E. 1994. A major histocompatibility complex class I-like Fc receptor cloned from human placenta: possible role in transfer of immunoglobulin G from mother to fetus. J. Exp. Med. 180:2377.
    • (1994) J. Exp. Med. , vol.180 , pp. 2377
    • Story, C.M.1    Mikulska, J.E.2    Simister, N.E.3
  • 13
    • 0034879134 scopus 로고    scopus 로고
    • The MHC class I related receptor, FcRn, plays an essential role in the maternofetal transfer of gammaglobulin in humans
    • Firan, M., Bawdon, R., Radu, C., Ober, R. J., Eaken, D., Antohe, F., Ghetie, V. and Ward, E. S. 2001. The MHC class I related receptor, FcRn, plays an essential role in the maternofetal transfer of gammaglobulin in humans. Int. Immunol. 13:993.
    • (2001) Int. Immunol. , vol.13 , pp. 993
    • Firan, M.1    Bawdon, R.2    Radu, C.3    Ober, R.J.4    Eaken, D.5    Antohe, F.6    Ghetie, V.7    Ward, E.S.8
  • 14
    • 0031093498 scopus 로고    scopus 로고
    • Delineation of the amino acid residues involved in transcytosis and catabolism of mouse IgG1
    • Medesan, C., Matesoi, D., Radu, C., Ghetie, V. and Ward, E. S. 1997. Delineation of the amino acid residues involved in transcytosis and catabolism of mouse IgG1. J. Immunol. 158:2211.
    • (1997) J. Immunol. , vol.158 , pp. 2211
    • Medesan, C.1    Matesoi, D.2    Radu, C.3    Ghetie, V.4    Ward, E.S.5
  • 16
    • 0035210960 scopus 로고    scopus 로고
    • Differences in promiscuity for antibody-FcRn interactions across species: Implications for therapeutic antibodies
    • Ober, R. J., Radu, C. G., Ghetie, V. and Ward, E. S. 2001. Differences in promiscuity for antibody-FcRn interactions across species: implications for therapeutic antibodies. Int. Immunol. 13:1551.
    • (2001) Int. Immunol. , vol.13 , pp. 1551
    • Ober, R.J.1    Radu, C.G.2    Ghetie, V.3    Ward, E.S.4
  • 17
    • 0028089908 scopus 로고
    • Crystal structure of the complex of rat neonatal Fc receptor with Fc
    • Burmeister, W. P., Huber, A. H. and Bjorkman, P. J. 1994. Crystal structure of the complex of rat neonatal Fc receptor with Fc. Nature 372:379.
    • (1994) Nature , vol.372 , pp. 379
    • Burmeister, W.P.1    Huber, A.H.2    Bjorkman, P.J.3
  • 18
    • 0028021594 scopus 로고
    • Localization of the site of the murine IgG1 molecule that is involved in binding to the murine intestinal Fc receptor
    • Kim, J. K., Tsen, M. F., Ghetie, V. and Ward, E. S. 1994. Localization of the site of the murine IgG1 molecule that is involved in binding to the murine intestinal Fc receptor. Eur. J. Immunol. 24:2429.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 2429
    • Kim, J.K.1    Tsen, M.F.2    Ghetie, V.3    Ward, E.S.4
  • 19
    • 0029842013 scopus 로고    scopus 로고
    • Localization of the site of the IgG molecule that regulates maternofetal transmission in mice
    • Medesan, C., Radu, C., Kim, J. K., Ghetie, V. and Ward, E. S. 1996. Localization of the site of the IgG molecule that regulates maternofetal transmission in mice. Eur. J. Immunol. 26:2533.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 2533
    • Medesan, C.1    Radu, C.2    Kim, J.K.3    Ghetie, V.4    Ward, E.S.5
  • 20
    • 0035012654 scopus 로고    scopus 로고
    • Crystal structure at 2.8 Å of an FcRn/heterodimeric Fc complex: Mechanism of pH dependent binding
    • Martin, W. L., West, A. P. J., Gan, L. and Bjorkman, P. J. 2001. Crystal structure at 2.8 Å of an FcRn/heterodimeric Fc complex: mechanism of pH dependent binding. Mol. Cell 7:867.
    • (2001) Mol. Cell , vol.7 , pp. 867
    • Martin, W.L.1    West, A.P.J.2    Gan, L.3    Bjorkman, P.J.4
  • 21
    • 0035794194 scopus 로고    scopus 로고
    • High resolution mapping of the binding site on human IgG1 for Fc gamma RI, Fc gamma RII, Fc gamma RIII, and FcRn and design of IgG1 variants with improved binding to the Fc gamma R
    • Shields, R. L., Namenuk, A. K., Hong, K., Meng, Y. G., Rae, J., Briggs, J., Xie, D., Lai, J., Stadlen, A., Li, B., Fox, J. A. and Presta, L. G. 2001. High resolution mapping of the binding site on human IgG1 for Fc gamma RI, Fc gamma RII, Fc gamma RIII, and FcRn and design of IgG1 variants with improved binding to the Fc gamma R. J. Biol. Chem. 276:6591.
    • (2001) J. Biol. Chem. , vol.276 , pp. 6591
    • Shields, R.L.1    Namenuk, A.K.2    Hong, K.3    Meng, Y.G.4    Rae, J.5    Briggs, J.6    Xie, D.7    Lai, J.8    Stadlen, A.9    Li, B.10    Fox, J.A.11    Presta, L.G.12
  • 22
    • 0028467948 scopus 로고
    • Investigation of the interaction between the class I MHC-related Fc receptor and its immunoglobulin G ligand
    • Raghavan, M., Chen, M. Y., Gastinel L. N. and Bjorkman, P. J. 1994. Investigation of the interaction between the class I MHC-related Fc receptor and its immunoglobulin G ligand, Immunity 1:303.
    • (1994) Immunity , vol.1 , pp. 303
    • Raghavan, M.1    Chen, M.Y.2    Gastinel, L.N.3    Bjorkman, P.J.4
  • 23
    • 0026559783 scopus 로고
    • Antibody framework residues affecting the conformation of the hypervariable loops
    • Foote, J. and Winter, G. 1992, Antibody framework residues affecting the conformation of the hypervariable loops. J. Mol. Biol. 224:487.
    • (1992) J. Mol. Biol. , vol.224 , pp. 487
    • Foote, J.1    Winter, G.2
  • 24
    • 0026803031 scopus 로고
    • The anti-tumor activity of an anti-CD22 immunotoxin in SCID mice with disseminated Daudi lymphoma is enhanced by either an anti-CD19 antibody or an anti-CD19 immunotoxin
    • Ghetie, M. A., Tucker, K., Richardson, J., Uhr J. W. and Vitetta, E. S. 1992. The anti-tumor activity of an anti-CD22 immunotoxin in SCID mice with disseminated Daudi lymphoma is enhanced by either an anti-CD19 antibody or an anti-CD19 immunotoxin. Blood 80:2315.
    • (1992) Blood , vol.80 , pp. 2315
    • Ghetie, M.A.1    Tucker, K.2    Richardson, J.3    Uhr, J.W.4    Vitetta, E.S.5
  • 25
    • 0030130749 scopus 로고    scopus 로고
    • The stoichiometry and affinity of the interaction of murine Fc fragments with the MHC class I-related receptor, FcRn
    • Popov, S., Hubbard, J. G., Kim, J., Ober, B., Ghetie, V. and Ward, E. S. 1996. The stoichiometry and affinity of the interaction of murine Fc fragments with the MHC class I-related receptor, FcRn. Mol. Immunol. 33:521.
    • (1996) Mol. Immunol. , vol.33 , pp. 521
    • Popov, S.1    Hubbard, J.G.2    Kim, J.3    Ober, B.4    Ghetie, V.5    Ward, E.S.6
  • 26
    • 0028085865 scopus 로고
    • Quantification of low density lipoprotein and transferrin endocytic sorting HEp2 cells using confocal microscopy
    • Ghosh, R. N., Gelman, D. L. and Maxfield, F. R. 1994. Quantification of low density lipoprotein and transferrin endocytic sorting HEp2 cells using confocal microscopy. J. Cell Sci. 107:2177.
    • (1994) J. Cell Sci. , vol.107 , pp. 2177
    • Ghosh, R.N.1    Gelman, D.L.2    Maxfield, F.R.3
  • 27
    • 0027243406 scopus 로고
    • Sorting of membrane components from endosomes and subsequent recycling to the cell surface occurs by a bulk flow process
    • Mayor, S., Presley, J. F. and Maxfield, F. R. 1993. Sorting of membrane components from endosomes and subsequent recycling to the cell surface occurs by a bulk flow process. J. Cell Biol. 121:1257.
    • (1993) J. Cell Biol. , vol.121 , pp. 1257
    • Mayor, S.1    Presley, J.F.2    Maxfield, F.R.3
  • 28
    • 0018688691 scopus 로고
    • Reversible accumulation of cholesteryl esters in macrophages incubated with acetylated lipoproteins
    • Brown, M. S., Goldstein, J. L., Krieger, M., Ho, Y. K. and Anderson, R. G. 1979. Reversible accumulation of cholesteryl esters in macrophages incubated with acetylated lipoproteins. J. Cell Biol. 82:597.
    • (1979) J. Cell Biol. , vol.82 , pp. 597
    • Brown, M.S.1    Goldstein, J.L.2    Krieger, M.3    Ho, Y.K.4    Anderson, R.G.5
  • 29
    • 0019297268 scopus 로고
    • The scavenger cell pathway for lipoprotein degradation: Specificity of the binding site that mediates the uptake of negatively-charged LDL by macrophages
    • Brown, M. S., Basu, S. K., Falck, J. R., Ho, Y. K. and Goldstein, J. L. 1980. The scavenger cell pathway for lipoprotein degradation: specificity of the binding site that mediates the uptake of negatively-charged LDL by macrophages. J. Supramol. Struct. 13:67.
    • (1980) J. Supramol. Struct. , vol.13 , pp. 67
    • Brown, M.S.1    Basu, S.K.2    Falck, J.R.3    Ho, Y.K.4    Goldstein, J.L.5
  • 30
    • 0028808880 scopus 로고
    • Analysis of the pH dependence of the neonatal Fc receptor/immunoglobulin G interaction using antibody and receptor variants
    • Raghavan, M., Bonagura, V. R., Morrison, S. L. and Bjorkman, P. J. 1995. Analysis of the pH dependence of the neonatal Fc receptor/immunoglobulin G interaction using antibody and receptor variants. Biochemistry 34:14649.
    • (1995) Biochemistry , vol.34 , pp. 14649
    • Raghavan, M.1    Bonagura, V.R.2    Morrison, S.L.3    Bjorkman, P.J.4
  • 32
    • 0025078215 scopus 로고
    • Pharmacokinetics of the mouse monoclonal antibody 17-1A in cancer patients receiving various treatment schedules
    • Frodin, J. E., Lefvert, A. K. and Mellstedt, H. 1990. Pharmacokinetics of the mouse monoclonal antibody 17-1A in cancer patients receiving various treatment schedules. Cancer Res. 50:4866.
    • (1990) Cancer Res. , vol.50 , pp. 4866
    • Frodin, J.E.1    Lefvert, A.K.2    Mellstedt, H.3
  • 33
  • 34
    • 0020616341 scopus 로고
    • Uptake and fate of exogenous immunoglobulin G in the perfused human placenta
    • Contractor, S. F., Eaton, B. M. and Stannard, P. J. 1983. Uptake and fate of exogenous immunoglobulin G in the perfused human placenta. J. Reprod. Immunol. 5:265.
    • (1983) J. Reprod. Immunol. , vol.5 , pp. 265
    • Contractor, S.F.1    Eaton, B.M.2    Stannard, P.J.3
  • 35
    • 0000770557 scopus 로고
    • Endocytic mechanism in protein transfer across the placenta
    • Wild, A. E. 1981. Endocytic mechanism in protein transfer across the placenta. Placenta Suppl. 1:165.
    • (1981) Placenta Suppl. , vol.1 , pp. 165
    • Wild, A.E.1
  • 36
    • 0003122064 scopus 로고
    • Intestinal transport of peroxidase-conjugated IgG fragments in the neonatal rat
    • Hemmings, W. A., ed., Cambridge University Press, Cambridge
    • Rodewald, R. B. 1976. Intestinal transport of peroxidase-conjugated IgG fragments in the neonatal rat. In Hemmings, W. A., ed., Maternofetal Transmission of Immunoglobulins, p. 137. Cambridge University Press, Cambridge.
    • (1976) Maternofetal Transmission of Immunoglobulins , pp. 137
    • Rodewald, R.B.1
  • 37
    • 0032794645 scopus 로고    scopus 로고
    • Intracellular traffic of the MHC class I-like IgG Fc receptor, FcRn, expressed in epithelial MDCK cells
    • Praetor, A., Ellinger, I. and Hunziker, W. 1999. Intracellular traffic of the MHC class I-like IgG Fc receptor, FcRn, expressed in epithelial MDCK cells. J. Cell Sci. 112:2291.
    • (1999) J. Cell Sci. , vol.112 , pp. 2291
    • Praetor, A.1    Ellinger, I.2    Hunziker, W.3
  • 38
    • 0034058526 scopus 로고    scopus 로고
    • Bidirectional transcytosis of IgG by the rat neonatal Fc receptor expressed in a rat kidney cell line: A system to study protein transport across epithelia
    • McCarthy, K. M., Yoong, Y. and Simister, N. E. 2000. Bidirectional transcytosis of IgG by the rat neonatal Fc receptor expressed in a rat kidney cell line: a system to study protein transport across epithelia. J. Cell Sci. 113:1277.
    • (2000) J. Cell Sci. , vol.113 , pp. 1277
    • McCarthy, K.M.1    Yoong, Y.2    Simister, N.E.3
  • 40
    • 0035113258 scopus 로고    scopus 로고
    • Expression of functionally active FcRn and the differentiated bidirectional transport of IgG in human placental endothelial cells
    • Antohe, F., Radulescu, L., Gafencu, A., Ghetie, V. and Simionescu, M. 2001. Expression of functionally active FcRn and the differentiated bidirectional transport of IgG in human placental endothelial cells. Hum. Immunol. 62:93.
    • (2001) Hum. Immunol. , vol.62 , pp. 93
    • Antohe, F.1    Radulescu, L.2    Gafencu, A.3    Ghetie, V.4    Simionescu, M.5
  • 41
    • 0033034401 scopus 로고    scopus 로고
    • IgG transport across trophoblast-derived BeWo cells: A model system to study IgG transport in the placenta
    • Ellinger, I., Schwab, M., Stefanescu, A., Hunziker, W. and Fuchs, R. 1999. IgG transport across trophoblast-derived BeWo cells: a model system to study IgG transport in the placenta. Eur. J. Immunol. 29:733.
    • (1999) Eur. J. Immunol. , vol.29 , pp. 733
    • Ellinger, I.1    Schwab, M.2    Stefanescu, A.3    Hunziker, W.4    Fuchs, R.5
  • 43
    • 0028156792 scopus 로고
    • The use of severe combined immunodeficiency mice to study the metabolism of human immunoglobulin G
    • Zuckier, L. S., Georgescu, L., Chang, C. J., Scharff, M. D. and Morrison, S. L. 1994. The use of severe combined immunodeficiency mice to study the metabolism of human immunoglobulin G. Cancer 73:794.
    • (1994) Cancer , vol.73 , pp. 794
    • Zuckier, L.S.1    Georgescu, L.2    Chang, C.J.3    Scharff, M.D.4    Morrison, S.L.5
  • 44
    • 0033393536 scopus 로고    scopus 로고
    • Mapping the site on human IgG for binding of the MHC class I-related receptor, FcRn
    • Kim, J. K., Firan, M., Radu, C. G., Kim, C. H., Ghetie, V. and Ward, E. S. 1999. Mapping the site on human IgG for binding of the MHC class I-related receptor, FcRn. Eur. J. Immunol. 29:2819.
    • (1999) Eur. J. Immunol. , vol.29 , pp. 2819
    • Kim, J.K.1    Firan, M.2    Radu, C.G.3    Kim, C.H.4    Ghetie, V.5    Ward, E.S.6


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