Differences in promiscuity for antibody-FcRn interactions across species: Implications for therapeutic antibodies

International Immunology

Volumn 13, Issue 12, 2001, Pages 1551-1559

  Ober, Raimund J ^a   Radu, Caius G ^a,b   Ghetie, Victor ^a   Ward, E Sally ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Antibody; FcRn; Interactions; Promiscuity; Therapeutic antibodies

Indexed keywords

ANTIBODY; FC RECEPTOR; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2B;

ANIMAL CELL; ANTIBODY COMBINING SITE; ANTIBODY SPECIFICITY; ARTICLE; CATTLE; CELL SURFACE; CIRCULATION; CLEARANCE; CONTROLLED STUDY; DRUG EFFICACY; GENETIC ENGINEERING; GENETIC TRANSFECTION; GUINEA PIG; HALF LIFE TIME; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PHARMACOKINETICS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RABBIT; RAT; RECEPTOR BINDING; REGULATORY MECHANISM; SHEEP; SPECIES DIFFERENCE; SURFACE PLASMON RESONANCE;

EID: 0035210960     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/13.12.1551     Document Type: Article

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