-
1
-
-
0034614637
-
The hallmarks of cancer
-
D. Hanahan, and R.A. Weinberg The hallmarks of cancer Cell 100 2000 57 70
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
2
-
-
0028104204
-
The ins and outs of Raf kinases
-
G. Daum, I. Eisenmann-Tappe, H.W. Fries, J. Troppmair, and U.R. Rapp The ins and outs of Raf kinases Trends Biochem. Sci. 19 1994 474 480
-
(1994)
Trends Biochem. Sci.
, vol.19
, pp. 474-480
-
-
Daum, G.1
Eisenmann-Tappe, I.2
Fries, H.W.3
Troppmair, J.4
Rapp, U.R.5
-
4
-
-
0345059765
-
Hedgehog signalling in cancer formation and maintenance
-
M. Pasca di Magliano, and M. Hebrok Hedgehog signalling in cancer formation and maintenance Nat. Rev. Cancer 3 2003 903 911
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 903-911
-
-
Pasca Di Magliano, M.1
Hebrok, M.2
-
5
-
-
1542327277
-
Inhibitors of JAKs/STATs and the kinases: A possible new cluster of drugs
-
C. Luo, and P. Laaja Inhibitors of JAKs/STATs and the kinases: a possible new cluster of drugs Drug Discov. Today 9 2004 268 275
-
(2004)
Drug Discov. Today
, vol.9
, pp. 268-275
-
-
Luo, C.1
Laaja, P.2
-
6
-
-
0036632368
-
The phosphatidylinositol 3-Kinase AKT pathway in human cancer
-
I. Vivanco, and C.L. Sawyers The phosphatidylinositol 3-Kinase AKT pathway in human cancer Nat. Rev. Cancer 2 2002 489 501
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 489-501
-
-
Vivanco, I.1
Sawyers, C.L.2
-
7
-
-
0842324623
-
Multiple niches for Notch in cancer: Context is everything
-
A.P. Weng, and J.C. Aster Multiple niches for Notch in cancer: context is everything Curr. Opin. Genet. Dev. 14 2004 48 54
-
(2004)
Curr. Opin. Genet. Dev.
, vol.14
, pp. 48-54
-
-
Weng, A.P.1
Aster, J.C.2
-
8
-
-
0037933857
-
Dominant oncogenes as cancer targets: Role of raf kinases and myc, two master regulators of phenotypic and genotypic stability
-
R. Rosenthal U. Wahn H. Wolf Schattauer Verlag New York
-
U.R. Rapp, and J. Troppmair Dominant oncogenes as cancer targets: role of raf kinases and myc, two master regulators of phenotypic and genotypic stability R. Rosenthal U. Wahn H. Wolf Einfluss von Genomprojekt und Pharmacogenetics auf die Medizinische Entwicklung Symposium der Novartis Stiftung 2002 Schattauer Verlag New York 25 42
-
(2002)
Einfluss Von Genomprojekt und Pharmacogenetics Auf Die Medizinische Entwicklung Symposium der Novartis Stiftung
, pp. 25-42
-
-
Rapp, U.R.1
Troppmair, J.2
-
9
-
-
0033001621
-
Reversible activation of c-Myc in skin: Induction of a complex neoplastic phenotype by a single oncogenic lesion
-
S. Pelengaris, T. Littlewood, M. Khan, G. Elia, and G. Evan Reversible activation of c-Myc in skin: induction of a complex neoplastic phenotype by a single oncogenic lesion Mol. Cell 3 1999 565 577
-
(1999)
Mol. Cell
, vol.3
, pp. 565-577
-
-
Pelengaris, S.1
Littlewood, T.2
Khan, M.3
Elia, G.4
Evan, G.5
-
10
-
-
0034036430
-
Lung-targeted expression of the c-Raf-1 kinase in transgenic mice exposes a novel oncogenic character of the wild-type protein
-
E. Kerkhoff, L.M. Fedorov, R. Siefken, A.O. Walter, T. Papadopoulos, and U.R. Rapp Lung-targeted expression of the c-Raf-1 kinase in transgenic mice exposes a novel oncogenic character of the wild-type protein Cell Growth Differ. 11 2000 185 190
-
(2000)
Cell Growth Differ.
, vol.11
, pp. 185-190
-
-
Kerkhoff, E.1
Fedorov, L.M.2
Siefken, R.3
Walter, A.O.4
Papadopoulos, T.5
Rapp, U.R.6
-
11
-
-
0033614998
-
Creation of human tumour cells with defined genetic elements
-
W.C. Hahn, C.M. Counter, A.S. Lundberg, R.L. Beijersbergen, M.W. Brooks, and R.A. Weinberg Creation of human tumour cells with defined genetic elements Nature 400 1999 464 468
-
(1999)
Nature
, vol.400
, pp. 464-468
-
-
Hahn, W.C.1
Counter, C.M.2
Lundberg, A.S.3
Beijersbergen, R.L.4
Brooks, M.W.5
Weinberg, R.A.6
-
12
-
-
0036463987
-
Disabling Abl-perspectives on Abl kinase regulation and cancer therapeutics
-
C.L. Sawyers Disabling Abl-perspectives on Abl kinase regulation and cancer therapeutics Cancer Cell 1 2002 13 15
-
(2002)
Cancer Cell
, vol.1
, pp. 13-15
-
-
Sawyers, C.L.1
-
13
-
-
0035902180
-
Oncogenic kinase signalling
-
P. Blume-Jensen, and T. Hunter Oncogenic kinase signalling Nature 411 2001 355 365
-
(2001)
Nature
, vol.411
, pp. 355-365
-
-
Blume-Jensen, P.1
Hunter, T.2
-
14
-
-
0028270718
-
Mitogen-activated protein kinase/extracellular signal-regulated protein kinase activation by oncogenes, serum, and 12-O-tetradecanoylphorbol-13-acetate requires Raf and is necessary for transformation
-
J. Troppmair, J.T. Bruder, H. Munoz, P.A. Lloyd, J. Kyriakis, and P. Banerjee Mitogen-activated protein kinase/extracellular signal-regulated protein kinase activation by oncogenes, serum, and 12-O-tetradecanoylphorbol-13-acetate requires Raf and is necessary for transformation J. Biol. Chem. 269 1994 7030 7035
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 7030-7035
-
-
Troppmair, J.1
Bruder, J.T.2
Munoz, H.3
Lloyd, P.A.4
Kyriakis, J.5
Banerjee, P.6
-
15
-
-
0032558692
-
A constitutively active and nuclear form of the MAP kinase ERK2 is sufficient for neurite outgrowth and cell transformation
-
M.J. Robinson, S.A. Stippec, E. Goldsmith, M.A. White, and M.H. Cobb A constitutively active and nuclear form of the MAP kinase ERK2 is sufficient for neurite outgrowth and cell transformation Curr. Biol. 8 1998 1141 1150
-
(1998)
Curr. Biol.
, vol.8
, pp. 1141-1150
-
-
Robinson, M.J.1
Stippec, S.A.2
Goldsmith, E.3
White, M.A.4
Cobb, M.H.5
-
16
-
-
0028228616
-
Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells
-
S. Cowley, H. Paterson, P. Kemp, and C.J. Marshall Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells Cell 77 1994 841 852
-
(1994)
Cell
, vol.77
, pp. 841-852
-
-
Cowley, S.1
Paterson, H.2
Kemp, P.3
Marshall, C.J.4
-
17
-
-
0035282334
-
Mammalian MAP kinase signalling cascades
-
L. Chang, and M. Karin Mammalian MAP kinase signalling cascades Nature 410 2001 37 40
-
(2001)
Nature
, vol.410
, pp. 37-40
-
-
Chang, L.1
Karin, M.2
-
18
-
-
0037032835
-
The protein kinase complement of the human genome
-
G. Manning, D.B. Whyte, R. Martinez, T. Hunter, and S. Sudarsanam The protein kinase complement of the human genome Science 298 2002 1912 1934
-
(2002)
Science
, vol.298
, pp. 1912-1934
-
-
Manning, G.1
Whyte, D.B.2
Martinez, R.3
Hunter, T.4
Sudarsanam, S.5
-
19
-
-
0028229012
-
The stress-activated protein kinase subfamily of c-Jun kinases
-
J.M. Kyriakis, P. Banerjee, E. Nikolakaki, T. Dai, E.A. Rubie, and M.F. Ahmad The stress-activated protein kinase subfamily of c-Jun kinases Nature 369 1994 156 160
-
(1994)
Nature
, vol.369
, pp. 156-160
-
-
Kyriakis, J.M.1
Banerjee, P.2
Nikolakaki, E.3
Dai, T.4
Rubie, E.A.5
Ahmad, M.F.6
-
20
-
-
0029885419
-
Selective interaction of JNK protein kinase isoforms with transcription factors
-
S. Gupta, T. Barrett, A.J. Whitmarsh, J. Cavanagh, H.K. Sluss, B. Derijard, and R.J. Davis Selective interaction of JNK protein kinase isoforms with transcription factors Eur. Mol. Biol. Org. J. 15 1996 2760 2770
-
(1996)
Eur. Mol. Biol. Org. J.
, vol.15
, pp. 2760-2770
-
-
Gupta, S.1
Barrett, T.2
Whitmarsh, A.J.3
Cavanagh, J.4
Sluss, H.K.5
Derijard, B.6
Davis, R.J.7
-
21
-
-
0030780804
-
Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene
-
D.D. Yang, C.Y. Kuan, A.J. Whitmarsh, M. Rincon, T.S. Zheng, and R.J. Davis Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene Nature 389 1997 865 870
-
(1997)
Nature
, vol.389
, pp. 865-870
-
-
Yang, D.D.1
Kuan, C.Y.2
Whitmarsh, A.J.3
Rincon, M.4
Zheng, T.S.5
Davis, R.J.6
-
22
-
-
0034668860
-
Synergistic activation of stress-activated protein kinase 1/c-Jun N-terminal kinase (SAPK1/JNK) isoforms by mitogen-activated protein kinase kinase 4 (MKK4) and MKK7
-
Y. Fleming, C.G. Armstrong, N. Morrice, A. Paterson, M. Goedert, and P. Cohen Synergistic activation of stress-activated protein kinase 1/c-Jun N-terminal kinase (SAPK1/JNK) isoforms by mitogen-activated protein kinase kinase 4 (MKK4) and MKK7 Biochem. J. 352 Pt 1 2000 145 154
-
(2000)
Biochem. J.
, vol.352
, Issue.1
, pp. 145-154
-
-
Fleming, Y.1
Armstrong, C.G.2
Morrice, N.3
Paterson, A.4
Goedert, M.5
Cohen, P.6
-
23
-
-
0036098552
-
AP-1 as a regulator of cell life and death
-
E. Shaulian, and M. Karin AP-1 as a regulator of cell life and death Nat. Cell. Biol. 4 2002 E131 E136
-
(2002)
Nat. Cell. Biol.
, vol.4
-
-
Shaulian, E.1
Karin, M.2
-
24
-
-
0034945723
-
Signaling by the JNK group of MAP kinases. c-jun N-terminal Kinase
-
C. Dong, R.J. Davis, and R.A. Flavell Signaling by the JNK group of MAP kinases. c-jun N-terminal Kinase J. Clin. Immunol. 21 2001 253 257
-
(2001)
J. Clin. Immunol.
, vol.21
, pp. 253-257
-
-
Dong, C.1
Davis, R.J.2
Flavell, R.A.3
-
26
-
-
0036776178
-
Epithelial fusions in the embryo
-
P. Martin, and W. Wood Epithelial fusions in the embryo Curr. Opin. Cell Biol. 14 2002 569 574
-
(2002)
Curr. Opin. Cell Biol.
, vol.14
, pp. 569-574
-
-
Martin, P.1
Wood, W.2
-
27
-
-
0037124314
-
Eiger, a TNF superfamily ligand that triggers the Drosophila JNK pathway
-
T. Igaki, H. Kanda, Y. Yamamoto-Goto, H. Kanuka, E. Kuranaga, T. Aigaki, and M. Miura Eiger, a TNF superfamily ligand that triggers the Drosophila JNK pathway Eur. Mol. Biol. Org. J. 21 2002 3009 3018
-
(2002)
Eur. Mol. Biol. Org. J.
, vol.21
, pp. 3009-3018
-
-
Igaki, T.1
Kanda, H.2
Yamamoto-Goto, Y.3
Kanuka, H.4
Kuranaga, E.5
Aigaki, T.6
Miura, M.7
-
28
-
-
0037162294
-
Evolution of TNF signaling mechanisms: JNK-dependent apoptosis triggered by Eiger, the Drosophila homolog of the TNF superfamily
-
E. Moreno, M. Yan, and K. Basler Evolution of TNF signaling mechanisms: JNK-dependent apoptosis triggered by Eiger, the Drosophila homolog of the TNF superfamily Curr. Biol. 12 2002 1263 1268
-
(2002)
Curr. Biol.
, vol.12
, pp. 1263-1268
-
-
Moreno, E.1
Yan, M.2
Basler, K.3
-
29
-
-
3042685022
-
The Caenorhabditis elegans MAPK phosphatase VHP-1 mediates a novel JNK-like signaling pathway in stress response
-
T. Mizuno, N. Hisamoto, T. Terada, T. Kondo, M. Adachi, and E. Nishida The Caenorhabditis elegans MAPK phosphatase VHP-1 mediates a novel JNK-like signaling pathway in stress response Eur. Mol. Biol. Org. J. (2004)
-
(2004)
Eur. Mol. Biol. Org. J.
-
-
Mizuno, T.1
Hisamoto, N.2
Terada, T.3
Kondo, T.4
Adachi, M.5
Nishida, E.6
-
30
-
-
0037902498
-
JNK and p38 MAP kinases in CD4+ and CD8+T cells
-
M. Rincon, and G. Pedraza-Alva JNK and p38 MAP kinases in CD4+ and CD8+T cells Immunol. Rev. 192 2003 131 142
-
(2003)
Immunol. Rev.
, vol.192
, pp. 131-142
-
-
Rincon, M.1
Pedraza-Alva, G.2
-
31
-
-
0034644522
-
Signal transduction by the JNK group of MAP kinases
-
R.J. Davis Signal transduction by the JNK group of MAP kinases Cell 103 2000 239 252
-
(2000)
Cell
, vol.103
, pp. 239-252
-
-
Davis, R.J.1
-
32
-
-
0034997845
-
Mitogen-activated protein (MAP) kinase pathways: Regulation and physiological functions
-
G. Pearson, F. Robinson, T. Beers Gibson, B.E. Xu, M. Karandikar, K. Berman, and M.H. Cobb Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions Endocr. Rev. 22 2001 153 183
-
(2001)
Endocr. Rev.
, vol.22
, pp. 153-183
-
-
Pearson, G.1
Robinson, F.2
Beers Gibson, T.3
Xu, B.E.4
Karandikar, M.5
Berman, K.6
Cobb, M.H.7
-
33
-
-
0036840971
-
Neuronal p38 MAPK signalling: An emerging regulator of cell fate and function in the nervous system
-
K. Takeda, and H. Ichijo Neuronal p38 MAPK signalling: an emerging regulator of cell fate and function in the nervous system Genes Cells 7 2002 1099 1111
-
(2002)
Genes Cells
, vol.7
, pp. 1099-1111
-
-
Takeda, K.1
Ichijo, H.2
-
34
-
-
0037178731
-
A conserved p38 MAP kinase pathway in Caenorhabditis elegans innate immunity
-
D.H. Kim, R. Feinbaum, G. Alloing, F.E. Emerson, D.A. Garsin, and H. Inoue A conserved p38 MAP kinase pathway in Caenorhabditis elegans innate immunity Science 297 2002 623 626
-
(2002)
Science
, vol.297
, pp. 623-626
-
-
Kim, D.H.1
Feinbaum, R.2
Alloing, G.3
Emerson, F.E.4
Garsin, D.A.5
Inoue, H.6
-
35
-
-
0034213138
-
P38 MAP kinases: Beyond the stress response
-
A.R. Nebreda, and A. Porras p38 MAP kinases: beyond the stress response Trends Biochem. Sci. 25 2000 257 260
-
(2000)
Trends Biochem. Sci.
, vol.25
, pp. 257-260
-
-
Nebreda, A.R.1
Porras, A.2
-
36
-
-
0029130410
-
Rapid induction of heparin-binding epidermal growth factor/diphtheria toxin receptor expression by Raf and Ras oncogenes
-
S.A. McCarthy, M.L. Samuels, C.A. Pritchard, J.A. Abraham, and M. McMahon Rapid induction of heparin-binding epidermal growth factor/diphtheria toxin receptor expression by Raf and Ras oncogenes Genes Dev. 9 1995 1953 1964
-
(1995)
Genes Dev.
, vol.9
, pp. 1953-1964
-
-
McCarthy, S.A.1
Samuels, M.L.2
Pritchard, C.A.3
Abraham, J.A.4
McMahon, M.5
-
37
-
-
0038374164
-
Cross-talk between JNK/SAPK and ERK/MAPK pathways: Sustained activation of JNK blocks ERK activation by mitogenic factors
-
Y.H. Shen, J. Godlewski, J. Zhu, P. Sathyanarayana, V. Leaner, and M.J. Birrer Cross-talk between JNK/SAPK and ERK/MAPK pathways: sustained activation of JNK blocks ERK activation by mitogenic factors J. Biol. Chem. 278 2003 26715 26721
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 26715-26721
-
-
Shen, Y.H.1
Godlewski, J.2
Zhu, J.3
Sathyanarayana, P.4
Leaner, V.5
Birrer, M.J.6
-
38
-
-
0035971506
-
Jun, the oncoprotein
-
P.K. Vogt Jun, the oncoprotein Oncogene 20 2001 2365 2377
-
(2001)
Oncogene
, vol.20
, pp. 2365-2377
-
-
Vogt, P.K.1
-
39
-
-
0035971432
-
AP-1 in mouse development and tumorigenesis
-
W. Jochum, E. Passegue, and E.F. Wagner AP-1 in mouse development and tumorigenesis Oncogene 20 2001 2401 2412
-
(2001)
Oncogene
, vol.20
, pp. 2401-2412
-
-
Jochum, W.1
Passegue, E.2
Wagner, E.F.3
-
40
-
-
0025082390
-
Obligatory wounding requirement for tumorigenesis in v-jun transgenic mice
-
A.C. Schuh, S.J. Keating, F.S. Monteclaro, P.K. Vogt, and M.L. Breitman Obligatory wounding requirement for tumorigenesis in v-jun transgenic mice Nature 346 1990 756 760
-
(1990)
Nature
, vol.346
, pp. 756-760
-
-
Schuh, A.C.1
Keating, S.J.2
Monteclaro, F.S.3
Vogt, P.K.4
Breitman, M.L.5
-
41
-
-
18444369000
-
Aberrantly expressed c-Jun and JunB are a hallmark of Hodgkin lymphoma cells, stimulate proliferation and synergize with NF-kappa B
-
S. Mathas, M. Hinz, I. Anagnostopoulos, D. Krappmann, A. Lietz, and F. Jundt Aberrantly expressed c-Jun and JunB are a hallmark of Hodgkin lymphoma cells, stimulate proliferation and synergize with NF-kappa B Eur. Mol. Biol. Org. J. 21 2002 4104 4113
-
(2002)
Eur. Mol. Biol. Org. J.
, vol.21
, pp. 4104-4113
-
-
Mathas, S.1
Hinz, M.2
Anagnostopoulos, I.3
Krappmann, D.4
Lietz, A.5
Jundt, F.6
-
42
-
-
0026425405
-
Transformation suppressor activity of a Jun transcription factor lacking its activation domain
-
A. Lloyd, N. Yancheva, and B. Wasylyk Transformation suppressor activity of a Jun transcription factor lacking its activation domain Nature 352 1991 635 638
-
(1991)
Nature
, vol.352
, pp. 635-638
-
-
Lloyd, A.1
Yancheva, N.2
Wasylyk, B.3
-
43
-
-
0028099742
-
Transformation by Raf and other oncogenes renders cells differentially sensitive to growth inhibition by a dominant negative c-jun mutant
-
U.R. Rapp, J. Troppmair, T. Beck, and M.J. Birrer Transformation by Raf and other oncogenes renders cells differentially sensitive to growth inhibition by a dominant negative c-jun mutant Oncogene 9 1994 3493 3498
-
(1994)
Oncogene
, vol.9
, pp. 3493-3498
-
-
Rapp, U.R.1
Troppmair, J.2
Beck, T.3
Birrer, M.J.4
-
44
-
-
0037462454
-
Liver tumor development. c-Jun antagonizes the proapoptotic activity of p53
-
R. Eferl, R. Ricci, L. Kenner, R. Zenz, J.P. David, M. Rath, and E.F. Wagner Liver tumor development. c-Jun antagonizes the proapoptotic activity of p53 Cell 112 2003 181 192
-
(2003)
Cell
, vol.112
, pp. 181-192
-
-
Eferl, R.1
Ricci, R.2
Kenner, L.3
Zenz, R.4
David, J.P.5
Rath, M.6
Wagner, E.F.7
-
45
-
-
0032479977
-
Differential regulation of c-Jun by ERK and JNK during PC12 cell differentiation
-
S. Leppa, R. Saffrich, W. Ansorge, and D. Bohmann Differential regulation of c-Jun by ERK and JNK during PC12 cell differentiation Eur. Mol. Biol. Org. J. 17 1998 4404 4413
-
(1998)
Eur. Mol. Biol. Org. J.
, vol.17
, pp. 4404-4413
-
-
Leppa, S.1
Saffrich, R.2
Ansorge, W.3
Bohmann, D.4
-
46
-
-
0029589929
-
The Bcr-Abl leukemia oncogene activates Jun kinase and requires Jun for transformation
-
A.B. Raitano, J.R. Halpern, T.M. Hambuch, and C.L. Sawyers The Bcr-Abl leukemia oncogene activates Jun kinase and requires Jun for transformation Proc. Natl Acad. Sci. USA 92 1995 11746 11750
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 11746-11750
-
-
Raitano, A.B.1
Halpern, J.R.2
Hambuch, T.M.3
Sawyers, C.L.4
-
47
-
-
0029887278
-
Constitutively activated JNK is associated with HTLV-1 mediated tumorigenesis
-
X. Xu, O. Heidenreich, I. Kitajima, K. McGuire, Q. Li, B. Su, and M. Nerenberg Constitutively activated JNK is associated with HTLV-1 mediated tumorigenesis Oncogene 13 1996 135 142
-
(1996)
Oncogene
, vol.13
, pp. 135-142
-
-
Xu, X.1
Heidenreich, O.2
Kitajima, I.3
McGuire, K.4
Li, Q.5
Su, B.6
Nerenberg, M.7
-
48
-
-
0030826412
-
A cytoplasmic inhibitor of the JNK signal transduction pathway
-
M. Dickens, J.S. Rogers, J. Cavanagh, A. Raitano, Z. Xia, and J.R. Halpern A cytoplasmic inhibitor of the JNK signal transduction pathway Science 277 1997 693 696
-
(1997)
Science
, vol.277
, pp. 693-696
-
-
Dickens, M.1
Rogers, J.S.2
Cavanagh, J.3
Raitano, A.4
Xia, Z.5
Halpern, J.R.6
-
49
-
-
0030927326
-
Activation of the JNK pathway is essential for transformation by the Met oncogene
-
G.A. Rodrigues, M. Park, and J. Schlessinger Activation of the JNK pathway is essential for transformation by the Met oncogene Eur. Mol. Biol. Org. J. 16 1997 2634 2645
-
(1997)
Eur. Mol. Biol. Org. J.
, vol.16
, pp. 2634-2645
-
-
Rodrigues, G.A.1
Park, M.2
Schlessinger, J.3
-
50
-
-
0031004266
-
Downstream of Crk adaptor signaling pathway: Activation of Jun kinase by v-Crk through the guanine nucleotide exchange protein C3G
-
S. Tanaka, T. Ouchi, and H. Hanafusa Downstream of Crk adaptor signaling pathway: activation of Jun kinase by v-Crk through the guanine nucleotide exchange protein C3G Proc. Natl Acad. Sci. USA 94 1997 2356 2361
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 2356-2361
-
-
Tanaka, S.1
Ouchi, T.2
Hanafusa, H.3
-
51
-
-
18544372157
-
Elevated JNK activation contributes to the pathogenesis of human brain tumors
-
M.A. Antonyak, L.C. Kenyon, A.K. Godwin, D.C. James, D.R. Emlet, and I. Okamoto Elevated JNK activation contributes to the pathogenesis of human brain tumors Oncogene 21 2002 5038 5046
-
(2002)
Oncogene
, vol.21
, pp. 5038-5046
-
-
Antonyak, M.A.1
Kenyon, L.C.2
Godwin, A.K.3
James, D.C.4
Emlet, D.R.5
Okamoto, I.6
-
52
-
-
0037224587
-
Constitutively active forms of c-Jun NH2-terminal kinase are expressed in primary glial tumors
-
H. Tsuiki, M. Tnani, I. Okamoto, L.C. Kenyon, D.R. Emlet, and M. Holgado-Madruga Constitutively active forms of c-Jun NH2-terminal kinase are expressed in primary glial tumors Cancer Res. 63 2003 250 255
-
(2003)
Cancer Res.
, vol.63
, pp. 250-255
-
-
Tsuiki, H.1
Tnani, M.2
Okamoto, I.3
Kenyon, L.C.4
Emlet, D.R.5
Holgado-Madruga, M.6
-
53
-
-
0034682264
-
Oncogenic transformation by ras and fos is mediated by c-Jun N-terminal phosphorylation
-
A. Behrens, W. Jochum, M. Sibilia, and E.F. Wagner Oncogenic transformation by ras and fos is mediated by c-Jun N-terminal phosphorylation Oncogene 19 2000 2657 2663
-
(2000)
Oncogene
, vol.19
, pp. 2657-2663
-
-
Behrens, A.1
Jochum, W.2
Sibilia, M.3
Wagner, E.F.4
-
54
-
-
0035872409
-
Suppression of skin tumorigenesis in c-Jun NH(2)-terminal kinase-2-deficient mice
-
N. Chen, M. Nomura, Q.B. She, W.Y. Ma, A.M. Bode, and L. Wang Suppression of skin tumorigenesis in c-Jun NH(2)-terminal kinase-2-deficient mice Cancer Res. 61 2001 3908 3912
-
(2001)
Cancer Res.
, vol.61
, pp. 3908-3912
-
-
Chen, N.1
Nomura, M.2
She, Q.B.3
Ma, W.Y.4
Bode, A.M.5
Wang, L.6
-
55
-
-
0036494195
-
Deficiency of c-Jun-NH(2)-terminal kinase-1 in mice enhances skin tumor development by 12-O-tetradecanoylphorbol-13-acetate
-
Q.B. She, N. Chen, A.M. Bode, R.A. Flavell, and Z. Dong Deficiency of c-Jun-NH(2)-terminal kinase-1 in mice enhances skin tumor development by 12-O-tetradecanoylphorbol-13-acetate Cancer Res. 62 2002 1343 1348
-
(2002)
Cancer Res.
, vol.62
, pp. 1343-1348
-
-
She, Q.B.1
Chen, N.2
Bode, A.M.3
Flavell, R.A.4
Dong, Z.5
-
56
-
-
0037337694
-
Suppression of Ras-stimulated transformation by the JNK signal transduction pathway
-
N.J. Kennedy, H.K. Sluss, S.N. Jones, D. Bar-Sagi, R.A. Flavell, and R.J. Davis Suppression of Ras-stimulated transformation by the JNK signal transduction pathway Genes Dev. 17 2003 629 637
-
(2003)
Genes Dev.
, vol.17
, pp. 629-637
-
-
Kennedy, N.J.1
Sluss, H.K.2
Jones, S.N.3
Bar-Sagi, D.4
Flavell, R.A.5
Davis, R.J.6
-
57
-
-
0037119423
-
Constitutive JNK activation in NIH 3T3 fibroblasts induces a partially transformed phenotype
-
U.E. Rennefahrt, B. Illert, E. Kerkhoff, J. Troppmair, and U.R. Rapp Constitutive JNK activation in NIH 3T3 fibroblasts induces a partially transformed phenotype J. Biol. Chem. 277 2002 29510 29518
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 29510-29518
-
-
Rennefahrt, U.E.1
Illert, B.2
Kerkhoff, E.3
Troppmair, J.4
Rapp, U.R.5
-
60
-
-
0033485261
-
Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation
-
D.V. Bulavin, S. Saito, M.C. Hollander, K. Sakaguchi, C.W. Anderson, E. Appella, and A.J. Fornace Jr. Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation Eur. Mol. Biol. Org. J. 18 1999 6845 6854
-
(1999)
Eur. Mol. Biol. Org. J.
, vol.18
, pp. 6845-6854
-
-
Bulavin, D.V.1
Saito, S.2
Hollander, M.C.3
Sakaguchi, K.4
Anderson, C.W.5
Appella, E.6
Fornace Jr., A.J.7
-
61
-
-
0036613212
-
Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity
-
D.V. Bulavin, O.N. Demidov, S. Saito, P. Kauraniemi, C. Phillips, and S.A. Amundson Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity Nat. Genet. 31 2002 210 215
-
(2002)
Nat. Genet.
, vol.31
, pp. 210-215
-
-
Bulavin, D.V.1
Demidov, O.N.2
Saito, S.3
Kauraniemi, P.4
Phillips, C.5
Amundson, S.A.6
-
62
-
-
0742270609
-
P38 alpha mitogen-activated protein kinase sensitizes cells to apoptosis induced by different stimuli
-
A. Porras, S. Zuluaga, E. Black, A. Valladares, A.M. Alvarez, and C. Ambrosino P38 alpha mitogen-activated protein kinase sensitizes cells to apoptosis induced by different stimuli Mol. Biol. Cell 15 2004 922 933
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 922-933
-
-
Porras, A.1
Zuluaga, S.2
Black, E.3
Valladares, A.4
Alvarez, A.M.5
Ambrosino, C.6
-
63
-
-
0029786329
-
Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway
-
J.N. Lavoie, G. L'Allemain, A. Brunet, R. Muller, and J. Pouyssegur Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway J. Biol. Chem. 271 1996 20608 20616
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 20608-20616
-
-
Lavoie, J.N.1
L'Allemain, G.2
Brunet, A.3
Muller, R.4
Pouyssegur, J.5
-
64
-
-
0037119470
-
The stress-activated protein kinases p38 alpha and JNK1 stabilize p21(Cip1) by phosphorylation
-
G.Y. Kim, S.E. Mercer, D.Z. Ewton, Z. Yan, K. Jin, and E. Friedman The stress-activated protein kinases p38 alpha and JNK1 stabilize p21(Cip1) by phosphorylation J. Biol. Chem. 277 2002 29792 29802
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 29792-29802
-
-
Kim, G.Y.1
Mercer, S.E.2
Ewton, D.Z.3
Yan, Z.4
Jin, K.5
Friedman, E.6
-
65
-
-
3242772188
-
The HBP1 transcriptional repressor and the p38 MAP kinase: Unlikely partners in G1 regulation and tumor suppression
-
A.S. Yee, E.K. Paulson, M.A. McDevitt, K. Rieger-Christ, I. Summerhayes, and S.P. Berasi The HBP1 transcriptional repressor and the p38 MAP kinase: unlikely partners in G1 regulation and tumor suppression Gene 336 2004 1 13
-
(2004)
Gene
, vol.336
, pp. 1-13
-
-
Yee, A.S.1
Paulson, E.K.2
McDevitt, M.A.3
Rieger-Christ, K.4
Summerhayes, I.5
Berasi, S.P.6
-
66
-
-
0038339253
-
Role of the p38 MAPK pathway in cisplatin-based therapy
-
J.H. Losa, C.P. Cobo, J.G. Viniegra, V.J. Sanchez-Arevalo Lobo, S. Roman y Cajal, and R. Sanchez-Prieto Role of the p38 MAPK pathway in cisplatin-based therapy Oncogene 22 2003 3998 4006
-
(2003)
Oncogene
, vol.22
, pp. 3998-4006
-
-
Losa, J.H.1
Cobo, C.P.2
Viniegra, J.G.3
Sanchez-Arevalo Lobo, V.J.4
Roman Cajal, Y.S.5
Sanchez-Prieto, R.6
-
67
-
-
10744228193
-
Tamoxifen inhibits cell proliferation via mitogen-activated protein kinase cascades in human ovarian cancer cell lines in a manner not dependent on the expression of estrogen receptor or the sensitivity to cisplatin
-
S. Mabuchi, M. Ohmichi, A. Kimura, Y. Ikebuchi, K. Hisamoto, and E. Arimoto-Ishida Tamoxifen inhibits cell proliferation via mitogen-activated protein kinase cascades in human ovarian cancer cell lines in a manner not dependent on the expression of estrogen receptor or the sensitivity to cisplatin Endocrinology 145 2004 1302 1313
-
(2004)
Endocrinology
, vol.145
, pp. 1302-1313
-
-
Mabuchi, S.1
Ohmichi, M.2
Kimura, A.3
Ikebuchi, Y.4
Hisamoto, K.5
Arimoto-Ishida, E.6
-
68
-
-
0038471347
-
Involvement of multiple signaling pathways in follicular lymphoma transformation: P38-mitogen-activated protein kinase as a target for therapy
-
K.S. Elenitoba-Johnson, S.D. Jenson, R.T. Abbott, R.A. Palais, S.D. Bohling, and Z. Lin Involvement of multiple signaling pathways in follicular lymphoma transformation: p38-mitogen-activated protein kinase as a target for therapy Proc. Natl Acad. Sci. USA 100 2003 7259 7264
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 7259-7264
-
-
Elenitoba-Johnson, K.S.1
Jenson, S.D.2
Abbott, R.T.3
Palais, R.A.4
Bohling, S.D.5
Lin, Z.6
-
69
-
-
2442644183
-
P38 MAP kinase signaling is necessary for rat chondrosarcoma cell proliferation
-
D. Halawani, R. Mondeh, L.A. Stanton, and F. Beier p38 MAP kinase signaling is necessary for rat chondrosarcoma cell proliferation Oncogene 23 2004 3726 3731
-
(2004)
Oncogene
, vol.23
, pp. 3726-3731
-
-
Halawani, D.1
Mondeh, R.2
Stanton, L.A.3
Beier, F.4
-
70
-
-
0030757691
-
Human mitogen-activated protein kinase kinase 4 as a candidate tumor suppressor
-
D.H. Teng, W.L. Perry 3rd, J.K. Hogan, M. Baumgard, R. Bell, and S. Berry Human mitogen-activated protein kinase kinase 4 as a candidate tumor suppressor Cancer Res. 57 1997 4177 4182
-
(1997)
Cancer Res.
, vol.57
, pp. 4177-4182
-
-
Teng, D.H.1
Perry III, W.L.2
Hogan, J.K.3
Baumgard, M.4
Bell, R.5
Berry, S.6
-
71
-
-
4043110739
-
Evidence of MKK4 pro-oncogenic activity in breast and pancreatic tumors
-
L. Wang, Y. Pan, and J.L. Dai Evidence of MKK4 pro-oncogenic activity in breast and pancreatic tumors Oncogene (2004)
-
(2004)
Oncogene
-
-
Wang, L.1
Pan, Y.2
Dai, J.L.3
-
72
-
-
0034693755
-
Tyrosine kinases and gastric cancer
-
W. Lin, H.W. Kao, D. Robinson, H.J. Kung, C.W. Wu, and H.C. Chen Tyrosine kinases and gastric cancer Oncogene 19 2000 5680 5689
-
(2000)
Oncogene
, vol.19
, pp. 5680-5689
-
-
Lin, W.1
Kao, H.W.2
Robinson, D.3
Kung, H.J.4
Wu, C.W.5
Chen, H.C.6
-
73
-
-
0033104956
-
Control of cell cycle progression by c-Jun is p53 dependent
-
M. Schreiber, A. Kolbus, F. Piu, A. Szabowski, U. Mohle-Steinlein, and J. Tian Control of cell cycle progression by c-Jun is p53 dependent Genes Dev. 13 1999 607 619
-
(1999)
Genes Dev.
, vol.13
, pp. 607-619
-
-
Schreiber, M.1
Kolbus, A.2
Piu, F.3
Szabowski, A.4
Mohle-Steinlein, U.5
Tian, J.6
-
74
-
-
0029998491
-
Cellular transformation and malignancy induced by ras require c-jun
-
R. Johnson, B. Spiegelman, D. Hanahan, and R. Wisdom Cellular transformation and malignancy induced by ras require c-jun Mol. Cell Biol. 16 1996 4504 4511
-
(1996)
Mol. Cell Biol.
, vol.16
, pp. 4504-4511
-
-
Johnson, R.1
Spiegelman, B.2
Hanahan, D.3
Wisdom, R.4
-
75
-
-
0027242180
-
C-jun is essential for normal mouse development and hepatogenesis
-
F. Hilberg, A. Aguzzi, N. Howells, and E.F. Wagner c-jun is essential for normal mouse development and hepatogenesis Nature 365 1993 179 181
-
(1993)
Nature
, vol.365
, pp. 179-181
-
-
Hilberg, F.1
Aguzzi, A.2
Howells, N.3
Wagner, E.F.4
-
76
-
-
0036730122
-
Survival signaling mediated by c-Jun NH(2)-terminal kinase in transformed B lymphoblasts
-
P. Hess, G. Pihan, C.L. Sawyers, R.A. Flavell, and R.J. Davis Survival signaling mediated by c-Jun NH(2)-terminal kinase in transformed B lymphoblasts Nat. Genet. 32 2002 201 205
-
(2002)
Nat. Genet.
, vol.32
, pp. 201-205
-
-
Hess, P.1
Pihan, G.2
Sawyers, C.L.3
Flavell, R.A.4
Davis, R.J.5
-
77
-
-
1242316958
-
JNK Suppresses apoptosis via phosphorylation of the proapoptotic Bcl-2 family protein BAD
-
C. Yu, Y. Minemoto, J. Zhang, J. Liu, F. Tang, and T.N. Bui JNK Suppresses apoptosis via phosphorylation of the proapoptotic Bcl-2 family protein BAD Mol. Cell 13 2004 329 340
-
(2004)
Mol. Cell
, vol.13
, pp. 329-340
-
-
Yu, C.1
Minemoto, Y.2
Zhang, J.3
Liu, J.4
Tang, F.5
Bui, T.N.6
-
78
-
-
0036849331
-
PKB binding proteins. Getting in on the Akt
-
D.P. Brazil, J. Park, and B.A. Hemmings PKB binding proteins. Getting in on the Akt Cell 111 2002 293 303
-
(2002)
Cell
, vol.111
, pp. 293-303
-
-
Brazil, D.P.1
Park, J.2
Hemmings, B.A.3
-
79
-
-
0345498292
-
Bcl-2 targets the protein kinase Raf-1 to mitochondria
-
H.G. Wang, U.R. Rapp, and J.C. Reed Bcl-2 targets the protein kinase Raf-1 to mitochondria Cell 87 1996 629 638
-
(1996)
Cell
, vol.87
, pp. 629-638
-
-
Wang, H.G.1
Rapp, U.R.2
Reed, J.C.3
-
80
-
-
0034164455
-
The c-Jun N-terminal kinase pathway and apoptotic signaling (review)
-
Y.R. Chen, and T.H. Tan The c-Jun N-terminal kinase pathway and apoptotic signaling (review) Int. J. Oncol. 16 2000 651 662
-
(2000)
Int. J. Oncol.
, vol.16
, pp. 651-662
-
-
Chen, Y.R.1
Tan, T.H.2
-
81
-
-
12144290513
-
MKK7 couples stress signalling to G2/M cell-cycle progression and cellular senescence
-
T. Wada, N. Joza, H.Y. Cheng, T. Sasaki, I. Kozieradzki, and K. Bachmaier MKK7 couples stress signalling to G2/M cell-cycle progression and cellular senescence Nat. Cell Biol. 6 2004 215 226
-
(2004)
Nat. Cell Biol.
, vol.6
, pp. 215-226
-
-
Wada, T.1
Joza, N.2
Cheng, H.Y.3
Sasaki, T.4
Kozieradzki, I.5
Bachmaier, K.6
-
82
-
-
0034920088
-
Activation of c-Jun NH2-terminal kinase/stress-activated protein kinase (JNK/SAPK) is critical for hypoxia-induced apoptosis of human malignant melanoma
-
M. Kunz, S. Ibrahim, D. Koczan, H.J. Thiesen, H.J. Kohler, and T. Acker Activation of c-Jun NH2-terminal kinase/stress-activated protein kinase (JNK/SAPK) is critical for hypoxia-induced apoptosis of human malignant melanoma Cell Growth Differ. 12 2001 137 145
-
(2001)
Cell Growth Differ.
, vol.12
, pp. 137-145
-
-
Kunz, M.1
Ibrahim, S.2
Koczan, D.3
Thiesen, H.J.4
Kohler, H.J.5
Acker, T.6
-
83
-
-
0033617186
-
Mitogen-activated protein kinase phosphatase-1 (MKP-1) expression is induced by low oxygen conditions found in solid tumor microenvironments. A candidate MKP for the inactivation of hypoxia-inducible stress-activated protein kinase/c-Jun N-terminal protein kinase activity
-
K.R. Laderoute, H.L. Mendonca, J.M. Calaoagan, A.M. Knapp, A.J. Giaccia, and P.J. Stork Mitogen-activated protein kinase phosphatase-1 (MKP-1) expression is induced by low oxygen conditions found in solid tumor microenvironments. A candidate MKP for the inactivation of hypoxia-inducible stress-activated protein kinase/c-Jun N-terminal protein kinase activity J. Biol. Chem. 274 1999 12890 12897
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 12890-12897
-
-
Laderoute, K.R.1
Mendonca, H.L.2
Calaoagan, J.M.3
Knapp, A.M.4
Giaccia, A.J.5
Stork, P.J.6
-
84
-
-
0036780251
-
Clinical translation of angiogenesis inhibitors
-
R. Kerbel, and J. Folkman Clinical translation of angiogenesis inhibitors Nat. Rev. Cancer 2 2002 727 739
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 727-739
-
-
Kerbel, R.1
Folkman, J.2
-
85
-
-
0036132872
-
C-Jun and hypoxia-inducible factor 1 functionally cooperate in hypoxia-induced gene transcription
-
A. Alfranca, M.D. Gutierrez, A. Vara, J. Aragones, F. Vidal, and M.O. Landazuri c-Jun and hypoxia-inducible factor 1 functionally cooperate in hypoxia-induced gene transcription Mol. Cell Biol. 22 2002 12 22
-
(2002)
Mol. Cell Biol.
, vol.22
, pp. 12-22
-
-
Alfranca, A.1
Gutierrez, M.D.2
Vara, A.3
Aragones, J.4
Vidal, F.5
Landazuri, M.O.6
-
86
-
-
0030770897
-
Characterization of signal transduction pathways in human bone marrow endothelial cells
-
Z.Y. Liu, R.K. Ganju, J.F. Wang, K. Schweitzer, B. Weksler, S. Avraham, and J.E. Groopman Characterization of signal transduction pathways in human bone marrow endothelial cells Blood 90 1997 2253 2259
-
(1997)
Blood
, vol.90
, pp. 2253-2259
-
-
Liu, Z.Y.1
Ganju, R.K.2
Wang, J.F.3
Schweitzer, K.4
Weksler, B.5
Avraham, S.6
Groopman, J.E.7
-
87
-
-
0030734010
-
P38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganization and cell migration in human endothelial cells
-
S. Rousseau, F. Houle, J. Landry, and J. Huot p38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganization and cell migration in human endothelial cells Oncogene 15 1997 2169 2177
-
(1997)
Oncogene
, vol.15
, pp. 2169-2177
-
-
Rousseau, S.1
Houle, F.2
Landry, J.3
Huot, J.4
-
88
-
-
0034714265
-
Stress-activated protein kinases (JNK and p38/HOG) are essential for vascular endothelial growth factor mRNA stability
-
G. Pages, E. Berra, J. Milanini, A.P. Levy, and J. Pouyssegur Stress-activated protein kinases (JNK and p38/HOG) are essential for vascular endothelial growth factor mRNA stability J. Biol. Chem. 275 2000 26484 26491
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 26484-26491
-
-
Pages, G.1
Berra, E.2
Milanini, J.3
Levy, A.P.4
Pouyssegur, J.5
-
89
-
-
2442429588
-
Effect of deoxyribozymes targeting c-Jun on solid tumor growth and angiogenesis in rodents
-
G. Zhang, C.R. Dass, E. Sumithran, N. Di Girolamo, L.Q. Sun, and L.M. Khachigian Effect of deoxyribozymes targeting c-Jun on solid tumor growth and angiogenesis in rodents J. Natl Cancer Inst. 96 2004 683 696
-
(2004)
J. Natl Cancer Inst.
, vol.96
, pp. 683-696
-
-
Zhang, G.1
Dass, C.R.2
Sumithran, E.3
Di Girolamo, N.4
Sun, L.Q.5
Khachigian, L.M.6
-
90
-
-
1642307340
-
Endostatin's antiangiogenic signaling network
-
A. Abdollahi, P. Hahnfeldt, C. Maercker, H.J. Grone, J. Debus, and W. Ansorge Endostatin's antiangiogenic signaling network Mol. Cell 13 2004 649 663
-
(2004)
Mol. Cell
, vol.13
, pp. 649-663
-
-
Abdollahi, A.1
Hahnfeldt, P.2
Maercker, C.3
Grone, H.J.4
Debus, J.5
Ansorge, W.6
-
91
-
-
0034635995
-
Matrix metalloproteinase-2 is required for the switch to the angiogenic phenotype in a tumor model
-
J. Fang, Y. Shing, D. Wiederschain, L. Yan, C. Butterfield, and G. Jackson Matrix metalloproteinase-2 is required for the switch to the angiogenic phenotype in a tumor model Proc. Natl Acad. Sci. USA 97 2000 3884 3889
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 3884-3889
-
-
Fang, J.1
Shing, Y.2
Wiederschain, D.3
Yan, L.4
Butterfield, C.5
Jackson, G.6
-
93
-
-
0033580213
-
Cot protooncoprotein activates the dual specificity kinases MEK-1 and SEK-1 and induces differentiation of PC12 cells
-
D. Hagemann, J. Troppmair, and U.R. Rapp Cot protooncoprotein activates the dual specificity kinases MEK-1 and SEK-1 and induces differentiation of PC12 cells Oncogene 18 1999 1391 1400
-
(1999)
Oncogene
, vol.18
, pp. 1391-1400
-
-
Hagemann, D.1
Troppmair, J.2
Rapp, U.R.3
-
94
-
-
0033135621
-
The JNK/SAPK activator mixed lineage kinase 3 (MLK3) transforms NIH 3T3 cells in a MEK-dependent fashion
-
J. Hartkamp, J. Troppmair, and U.R. Rapp The JNK/SAPK activator mixed lineage kinase 3 (MLK3) transforms NIH 3T3 cells in a MEK-dependent fashion Cancer Res. 59 1999 2195 2202
-
(1999)
Cancer Res.
, vol.59
, pp. 2195-2202
-
-
Hartkamp, J.1
Troppmair, J.2
Rapp, U.R.3
-
95
-
-
0032514363
-
Activation of NF-kappa B by oncogenic Raf in HEK 293 cells occurs through autocrine recruitment of the stress kinase cascade
-
J. Troppmair, J. Hartkamp, and U.R. Rapp Activation of NF-kappa B by oncogenic Raf in HEK 293 cells occurs through autocrine recruitment of the stress kinase cascade Oncogene 17 1998 685 690
-
(1998)
Oncogene
, vol.17
, pp. 685-690
-
-
Troppmair, J.1
Hartkamp, J.2
Rapp, U.R.3
-
96
-
-
12944305960
-
Raf induces NF-kappaB by membrane shuttle kinase MEKK1, a signaling pathway critical for transformation
-
B. Baumann, C.K. Weber, J. Troppmair, S. Whiteside, A. Israel, U.R. Rapp, and T. Wirth Raf induces NF-kappaB by membrane shuttle kinase MEKK1, a signaling pathway critical for transformation Proc. Natl Acad. Sci. USA 97 2000 4615 4620
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 4615-4620
-
-
Baumann, B.1
Weber, C.K.2
Troppmair, J.3
Whiteside, S.4
Israel, A.5
Rapp, U.R.6
Wirth, T.7
-
97
-
-
0035102807
-
Apoptosis suppression by Raf-1 and MEK1 requires MEK- and phosphatidylinositol 3-kinase-dependent signals
-
A. von Gise, P. Lorenz, C. Wellbrock, B. Hemmings, F. Berberich-Siebelt, U.R. Rapp, and J. Troppmair Apoptosis suppression by Raf-1 and MEK1 requires MEK- and phosphatidylinositol 3-kinase-dependent signals Mol. Cell Biol. 21 2001 2324 2336
-
(2001)
Mol. Cell Biol.
, vol.21
, pp. 2324-2336
-
-
Von Gise, A.1
Lorenz, P.2
Wellbrock, C.3
Hemmings, B.4
Berberich-Siebelt, F.5
Rapp, U.R.6
Troppmair, J.7
-
98
-
-
18444374405
-
Mutations of the BRAF gene in human cancer
-
H. Davies, G.R. Bignell, C. Cox, P. Stephens, S. Edkins, and S. Clegg Mutations of the BRAF gene in human cancer Nature 417 2002 949 954
-
(2002)
Nature
, vol.417
, pp. 949-954
-
-
Davies, H.1
Bignell, G.R.2
Cox, C.3
Stephens, P.4
Edkins, S.5
Clegg, S.6
-
99
-
-
0031936353
-
Ras signalling and apoptosis
-
J. Downward Ras signalling and apoptosis Curr. Opin. Genet. Dev. 8 1998 49 54
-
(1998)
Curr. Opin. Genet. Dev.
, vol.8
, pp. 49-54
-
-
Downward, J.1
-
100
-
-
0032522816
-
High-intensity Raf signals convert mitotic cell cycling into cellular growth
-
E. Kerkhoff, and U.R. Rapp High-intensity Raf signals convert mitotic cell cycling into cellular growth Cancer Res. 58 1998 1636 1640
-
(1998)
Cancer Res.
, vol.58
, pp. 1636-1640
-
-
Kerkhoff, E.1
Rapp, U.R.2
|