메뉴 건너뛰기




Volumn 11, Issue 4, 2000, Pages 185-190

Lung-targeted expression of the c-Raf-1 kinase in transgenic mice exposes a novel oncogenic character of the wild-type protein

Author keywords

[No Author keywords available]

Indexed keywords

C RAF 1 KINASE; GUANOSINE TRIPHOSPHATASE; PROTEIN KINASE; PROTEIN TYROSINE KINASE; RAF PROTEIN; RAS PROTEIN; UNCLASSIFIED DRUG;

EID: 0034036430     PISSN: 10449523     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (96)

References (26)
  • 1
    • 0025343230 scopus 로고
    • Signal transduction by receptors with tyrosine kinase activity
    • Ullrich, A., and Schlessinger, J. Signal transduction by receptors with tyrosine kinase activity. Cell, 61: 203-212, 1990.
    • (1990) Cell , vol.61 , pp. 203-212
    • Ullrich, A.1    Schlessinger, J.2
  • 2
    • 0004210231 scopus 로고
    • London: Jones and Bartlett Publishers
    • Cooper, G. M. Oncogenes. London: Jones and Bartlett Publishers, 1995.
    • (1995) Oncogenes
    • Cooper, G.M.1
  • 3
    • 0029955128 scopus 로고    scopus 로고
    • Control of ras activation
    • Downward, J. Control of ras activation. Cancer Surv., 27: 87-100, 1996.
    • (1996) Cancer Surv. , vol.27 , pp. 87-100
    • Downward, J.1
  • 4
    • 0028175091 scopus 로고
    • Raf meets Ras: Completing the framework of a signal transduction pathway
    • Avruch, J., Zhang, X., and Kyriakis, J. M. Raf meets Ras: completing the framework of a signal transduction pathway. Trends Biochem. Sci., 19: 279-283, 1994.
    • (1994) Trends Biochem. Sci. , vol.19 , pp. 279-283
    • Avruch, J.1    Zhang, X.2    Kyriakis, J.M.3
  • 6
    • 0023898932 scopus 로고    scopus 로고
    • The Ras family and human carcinogenesis
    • Bos, J. L. The Ras family and human carcinogenesis. Mutat. Res., 195: 255-271.
    • Mutat. Res. , vol.195 , pp. 255-271
    • Bos, J.L.1
  • 7
    • 0024545162 scopus 로고
    • Definition of the human Raf amino-terminal regulatory region by deletion mutagenesis
    • Stanton, V. P., Nicholas, D. W., Laudano, A. P., and Cooper, G. M. Definition of the human Raf amino-terminal regulatory region by deletion mutagenesis. Mol. Cell. Biol., 9: 639-647, 1989.
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 639-647
    • Stanton, V.P.1    Nicholas, D.W.2    Laudano, A.P.3    Cooper, G.M.4
  • 9
    • 0024513104 scopus 로고
    • Expression of raf oncogenes activates PEA1 transcription factor motif
    • Wasylyk, C., Wasylyk, B., Heidecker, G., Huleihel, M., and Rapp, U. R. Expression of raf oncogenes activates PEA1 transcription factor motif. Mol. Cell. Biol., 9: 2247-2250, 1989.
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 2247-2250
    • Wasylyk, C.1    Wasylyk, B.2    Heidecker, G.3    Huleihel, M.4    Rapp, U.R.5
  • 10
    • 0027364980 scopus 로고
    • Critical tyrosine residues regulate the enzymatic and biological activity of Raf-1 kinase
    • Fabian, J. R., Daar, I. O., and Morrison, D. K. Critical tyrosine residues regulate the enzymatic and biological activity of Raf-1 kinase. Mol. Cell. Biol., 13: 7170-7179, 1993.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 7170-7179
    • Fabian, J.R.1    Daar, I.O.2    Morrison, D.K.3
  • 13
    • 0028962328 scopus 로고
    • The mek kinase activity of the catalytic domain of Raf-1 is regulated independently of Ras binding in T cells
    • Whitehurst, C. E., Owaki, H., Bruder, J. T., Rapp, U. R., and Geppert, T. D. The Mek kinase activity of the catalytic domain of Raf-1 is regulated independently of Ras binding in T cells. J. Biol. Chem., 270: 5594-5599, 1995.
    • (1995) J. Biol. Chem. , vol.270 , pp. 5594-5599
    • Whitehurst, C.E.1    Owaki, H.2    Bruder, J.T.3    Rapp, U.R.4    Geppert, T.D.5
  • 16
    • 0026673788 scopus 로고
    • Simian virus 40 large T antigen directed by transcriptional elements of the human surfactant protein C gene produces pulmonary adenocarcinomas in transgenic mice
    • Wikenheiser, K. A., Clark, J. C., Linnoila, I., Stahlman, M. T., and Whitsett, J. A. Simian virus 40 large T antigen directed by transcriptional elements of the human surfactant protein C gene produces pulmonary adenocarcinomas in transgenic mice. Cancer Res., 52: 5342-5352, 1992.
    • (1992) Cancer Res. , vol.52 , pp. 5342-5352
    • Wikenheiser, K.A.1    Clark, J.C.2    Linnoila, I.3    Stahlman, M.T.4    Whitsett, J.A.5
  • 18
    • 0029952544 scopus 로고    scopus 로고
    • Arrested lung morphogenesis in transgenic mice bearing an SP-C-TGF-β1 chimeric gene
    • Zhou, L., Dey, C. R., Wert, S. E., and Whitsett, J. A. Arrested lung morphogenesis in transgenic mice bearing an SP-C-TGF-β1 chimeric gene. Dev, Biol., 175: 227-238, 1996.
    • (1996) Dev, Biol. , vol.175 , pp. 227-238
    • Zhou, L.1    Dey, C.R.2    Wert, S.E.3    Whitsett, J.A.4
  • 19
    • 0030111431 scopus 로고    scopus 로고
    • A human SP-C promoter fragment targets α1-proteinase inhibitor gene expression to lung alveolar type II cells in transgenic mice
    • Degryse, E., De Santi, M. M., Dietrich, M., Hadji, D. A., Spetz, J. F., Villeval, D., and Lungarella, G. A human SP-C promoter fragment targets α1-proteinase inhibitor gene expression to lung alveolar type II cells in transgenic mice. Transgenic Res., 5: 139-143, 1996.
    • (1996) Transgenic Res. , vol.5 , pp. 139-143
    • Degryse, E.1    De Santi, M.M.2    Dietrich, M.3    Hadji, D.A.4    Spetz, J.F.5    Villeval, D.6    Lungarella, G.7
  • 20
    • 0032171021 scopus 로고    scopus 로고
    • Lung-specific expression of adenovirus E3-14.7K in transgenic mice attenuates adenoviral vector mediated lung inflamation and enhances transgene expression
    • Harrod, K. S., Hermiston, T. W., Trapnell, B. C., Wold, W. S., and Whitsett, J. A. Lung-specific expression of adenovirus E3-14.7K in transgenic mice attenuates adenoviral vector mediated lung inflamation and enhances transgene expression. Hum. Gene Ther., 9: 1885-1898, 1998.
    • (1998) Hum. Gene Ther. , vol.9 , pp. 1885-1898
    • Harrod, K.S.1    Hermiston, T.W.2    Trapnell, B.C.3    Wold, W.S.4    Whitsett, J.A.5
  • 21
    • 0033004255 scopus 로고    scopus 로고
    • Pulmonary epithelial expression of human α1-antitrypsin in transgenic mice results in delivery of α1-antitrypsin protein to the interstitium
    • Dhami, R., Zay, K., Gilks, B., Porter, S., Wright, J. L., and Churg, A. Pulmonary epithelial expression of human α1-antitrypsin in transgenic mice results in delivery of α1-antitrypsin protein to the interstitium. J. Mol. Med., 77-377-385, 1999.
    • (1999) J. Mol. Med. , vol.77 , pp. 377-385
    • Dhami, R.1    Zay, K.2    Gilks, B.3    Porter, S.4    Wright, J.L.5    Churg, A.6
  • 22
    • 0026596576 scopus 로고
    • TPA and Ras-induced expression from AP-1/Ets-driven promoters requires Raf-1 kinases
    • Bruder, J. T., Heidecker, G., and Rapp, U. R. TPA and Ras-induced expression from AP-1/Ets-driven promoters requires Raf-1 kinases. Genes Dev., 6: 545-556, 1992.
    • (1992) Genes Dev. , vol.6 , pp. 545-556
    • Bruder, J.T.1    Heidecker, G.2    Rapp, U.R.3
  • 24
    • 0033588844 scopus 로고    scopus 로고
    • Modeling human lung cancer in mice: Similarities and shortcomings
    • Tuveson, D. A., and Jacks, T. Modeling human lung cancer in mice: similarities and shortcomings. Oncogene, 18: 5318-5324, 1999.
    • (1999) Oncogene , vol.18 , pp. 5318-5324
    • Tuveson, D.A.1    Jacks, T.2
  • 25
    • 0022623644 scopus 로고
    • The complete coding sequence of the human raf oncogene and the corresponding structure of the c-raf-1 gene
    • Bonner, T. I., Oppermann, H., Seeburg, I., Kerby, S. B., Gunnel, M. A., Young, A. C., and Rapp, U. R. The complete coding sequence of the human raf oncogene and the corresponding structure of the c-raf-1 gene. Nucleic Acids Res., 14: 1009-1025, 1986.
    • (1986) Nucleic Acids Res. , vol.14 , pp. 1009-1025
    • Bonner, T.I.1    Oppermann, H.2    Seeburg, I.3    Kerby, S.B.4    Gunnel, M.A.5    Young, A.C.6    Rapp, U.R.7
  • 26
    • 0030901947 scopus 로고    scopus 로고
    • Induction of cell proliferation in quiescent NIH 3T3 cells by oncogenic c-Raf-1
    • Kerkhoff, E., and Rapp, U. R. Induction of cell proliferation in quiescent NIH 3T3 cells by oncogenic c-Raf-1. Mol. Cell. Biol., 17: 2576-2586, 1997.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 2576-2586
    • Kerkhoff, E.1    Rapp, U.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.