Aberrant histone acetylation, altered transcription, and retinal degeneration in a Drosophila model of polyglutamine disease are rescued by CREB-binding protein

Genes and Development

Volumn 17, Issue 12, 2003, Pages 1463-1468

  Taylor, J Paul ^a   Taye, Addis A ^a   Campbell, Catherine ^a,c   Kazemi Esfarjani, Parsa ^b   Fischbeck, Kenneth H ^a   Min, Kyung Tai ^a  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^b UNIVERSITY AT BUFFALO   (United States)

^c GENERAL DYNAMICS   (United States)

Author keywords

CREB binding protein (CBP); Drosophila; Gene expression analysis; Histone acetylation; Polyglutamine; Retinal degeneration

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; HISTONE; HISTONE ACETYLTRANSFERASE; POLYGLUTAMINE;

ACETYLATION; ADOLESCENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; DEGENERATIVE DISEASE; DROSOPHILA; GENE FUNCTION; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; MORPHOLOGY; NERVE DEGENERATION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RETINA DEGENERATION;

ACETYLATION; ACETYLTRANSFERASES; ANIMALS; CELL DEATH; CREB-BINDING PROTEIN; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; HISTONE ACETYLTRANSFERASES; MUTATION; NEURONS; NUCLEAR PROTEINS; PEPTIDES; RETINAL DEGENERATION; SACCHAROMYCES CEREVISIAE PROTEINS; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC;

ANIMALIA; EUKARYOTA;

EID: 0038722748     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.1087503     Document Type: Article

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