Multidrug resistance protein 4 (ABCC4)-mediated ATP hydrolysis: Effect of transport substrates and characterization of the post-hydrolysis transition state

Journal of Biological Chemistry

Volumn 279, Issue 47, 2004, Pages 48855-48864

  Sauna, Zuben E ^a   Nandigama, Krishnamachary ^a   Ambudkar, Suresh V ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINETRIPHOSPHATE; CELLS; DRUG DOSAGE; HYDROLYSIS; SUBSTRATES;

GLYCOPROTEINS; INSECT CELLS; MULTIDRUG RESISTANCE PROTEINS 4 (MRP4);

PROTEINS;

ADEFOVIR; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; ADENOSINE TRIPHOSPHATE DERIVATIVE; BERYLLIUM FLUORIDE; COBALT; FLUORIDE; GLYCOPROTEIN P; MAGNESIUM ION; MANGANESE; METHOTREXATE; MULTIDRUG RESISTANCE PROTEIN 4; ORTHOVANADIC ACID; PROSTAGLANDIN E1; PROSTAGLANDIN E2; UNCLASSIFIED DRUG; ZIDOVUDINE;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; ENZYME ACTIVITY; INHIBITION KINETICS; NONHUMAN; NUCLEOTIDE BINDING SITE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN HYDROLYSIS; PROTEIN PROTEIN INTERACTION;

ADENINE; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATASES; ADENOSINE TRIPHOSPHATE; ANIMALS; ANTINEOPLASTIC AGENTS; BERYLLIUM; BIOLOGICAL TRANSPORT; CATALYSIS; CATIONS; CELL LINE; CELL MEMBRANE; CHELATING AGENTS; COBALT; DINOPROSTONE; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; EDETIC ACID; FLUORIDES; HUMANS; HYDROLYSIS; INSECTS; KINETICS; MAGNESIUM; MANGANESE; METHOTREXATE; MODELS, BIOLOGICAL; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; NUCLEOTIDES; P-GLYCOPROTEIN; PHOSPHONIC ACIDS; PROTEIN BINDING; SUBSTRATE SPECIFICITY; VANADATES; ZIDOVUDINE;

ANIMALIA; INSECTA;

EID: 10344227755     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M408849200     Document Type: Article

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