The radioprotective effect of the 24 kDa FGF-2 isoform in HeLa cells is related to an increased expression and activity of the DNA dependent protein kinase (DNA-PK) catalytic subunit

Oncogene

Volumn 21, Issue 42, 2002, Pages 6471-6479

  Ader, Isabelle ^a   Muller, Catherine ^b   Bonnet, Jacques ^a   Favre, Gilles ^a   Cohen Jonathan, Elizabeth ^a   Salles, Bernard ^b   Toulas, Christine ^a  

^a INSTITUT CLAUDIUS REGAUD   (France)

^b CNRS   (France)

Author keywords

DNA repair; DNA PK; High molecular form of FGF 2; NHEJ; Radioresistance

Indexed keywords

DNA DEPENDENT PROTEIN KINASE; DOUBLE STRANDED DNA; FIBROBLAST GROWTH FACTOR 2; HOLOENZYME; ISOPROTEIN; KU ANTIGEN; WORTMANNIN;

ARTICLE; CYTOTOXICITY; DNA DAMAGE; DNA REPAIR; ENZYME ACTIVITY; ENZYME SUBUNIT; GENE OVEREXPRESSION; HELA CELL; HUMAN; HUMAN CELL; IONIZING RADIATION; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MODIFICATION; RADIATION PROTECTION; RADIOSENSITIVITY; SENSITIZATION;

ANDROSTADIENES; ANTIGENS, NUCLEAR; BLOTTING, WESTERN; DNA DAMAGE; DNA HELICASES; DNA REPAIR; DNA-ACTIVATED PROTEIN KINASE; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FIBROBLAST GROWTH FACTOR 2; HELA CELLS; HUMANS; NUCLEAR PROTEINS; PHENOTYPE; PROTEIN ISOFORMS; PROTEIN-SERINE-THREONINE KINASES; RADIATION TOLERANCE; RADIATION-PROTECTIVE AGENTS; RNA; TIME FACTORS; TRANSCRIPTION, GENETIC; UP-REGULATION;

STAPHYLOCOCCUS PHAGE 3A;

EID: 0037136673     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1205838     Document Type: Article

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