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Volumn 7, Issue 13, 2000, Pages 1126-1131

Modification of vascular tone using iNOS under the control of a radiation-inducible promoter

Author keywords

Gene therapy; INOS; Promoter; Radiation; Tumour vasculature

Indexed keywords

COMPLEMENTARY DNA; GREEN FLUORESCENT PROTEIN; ISOPROTEIN; N(G) NITROARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; PHENYLEPHRINE; VASODILATOR AGENT;

EID: 0033911027     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301224     Document Type: Article
Times cited : (51)

References (30)
  • 2
    • 0027197246 scopus 로고
    • Recombinant fibroblast growth-factor-1 promotes intimal hyperplasia and angiogenesis in arteries in vivo
    • Nabel EG et al. Recombinant fibroblast growth-factor-1 promotes intimal hyperplasia and angiogenesis in arteries in vivo. Nature 1993; 362: 844-846.
    • (1993) Nature , vol.362 , pp. 844-846
    • Nabel, E.G.1
  • 3
    • 0028040836 scopus 로고
    • Gene therapy for vascular smooth muscle cell proliferation after arterial injury
    • Ohno T et al. Gene therapy for vascular smooth muscle cell proliferation after arterial injury. Science 1994; 265: 781-784.
    • (1994) Science , vol.265 , pp. 781-784
    • Ohno, T.1
  • 4
    • 0033000339 scopus 로고    scopus 로고
    • Gene therapy of glioblastoma multiforme via combined expression of suicide and cytokine genes: A pilot study in humans
    • Palu G et al. Gene therapy of glioblastoma multiforme via combined expression of suicide and cytokine genes: a pilot study in humans. Gene Therapy 1999; 6: 330-337.
    • (1999) Gene Therapy , vol.6 , pp. 330-337
    • Palu, G.1
  • 5
    • 0032971662 scopus 로고    scopus 로고
    • Adenovector-mediated gene delivery of interleukin-2 in metastatic breast cancer and melanoma: Results of a phase 1 clinical trial
    • Stewart AK et al. Adenovector-mediated gene delivery of interleukin-2 in metastatic breast cancer and melanoma: results of a phase 1 clinical trial. Gene Therapy 1999; 3: 350-363.
    • (1999) Gene Therapy , vol.3 , pp. 350-363
    • Stewart, A.K.1
  • 6
    • 0025093973 scopus 로고
    • Vascular attack as a therapeutic strategy for cancer
    • Denekamp J. Vascular attack as a therapeutic strategy for cancer. Cancer Metast Rev 1990; 9: 267-282.
    • (1990) Cancer Metast Rev , vol.9 , pp. 267-282
    • Denekamp, J.1
  • 7
    • 0031901747 scopus 로고    scopus 로고
    • Molecular biology of nitric oxide synthases
    • Geller DA, Billiar TR. Molecular biology of nitric oxide synthases. Cancer Metast Rev 1998; 17: 7-23.
    • (1998) Cancer Metast Rev , vol.17 , pp. 7-23
    • Geller, D.A.1    Billiar, T.R.2
  • 8
    • 0027372580 scopus 로고
    • Purification and cDNA sequence of an iNOS from a tumour cell line
    • Sherman PA et al. Purification and cDNA sequence of an iNOS from a tumour cell line. Biochemistry 1993; 32: 11600-11605.
    • (1993) Biochemistry , vol.32 , pp. 11600-11605
    • Sherman, P.A.1
  • 9
    • 0028215982 scopus 로고
    • NOS activity in human gynecological cancer
    • Thomsen LL et al. NOS activity in human gynecological cancer. Cancer Res 1994; 54: 1352-1354.
    • (1994) Cancer Res , vol.54 , pp. 1352-1354
    • Thomsen, L.L.1
  • 10
    • 0028814664 scopus 로고
    • Inducible nitric oxide synthase in a human glioblastoma cell line
    • Fujisawa H et al. Inducible nitric oxide synthase in a human glioblastoma cell line. J Neurochem 1995; 64: 85-91.
    • (1995) J Neurochem , vol.64 , pp. 85-91
    • Fujisawa, H.1
  • 11
    • 0028567517 scopus 로고
    • Tissue-specific targeting of retroviral vectors through ligand-receptor interactions
    • Kasahara N, Dozy A, Kan Y. Tissue-specific targeting of retroviral vectors through ligand-receptor interactions. Science 1994; 266: 1373-1376.
    • (1994) Science , vol.266 , pp. 1373-1376
    • Kasahara, N.1    Dozy, A.2    Kan, Y.3
  • 12
    • 0028127077 scopus 로고
    • Enhancer sequences of the DF3 gene regulate expression of the herpes simplex virus thymidine kinase gene
    • Manome Y et al. Enhancer sequences of the DF3 gene regulate expression of the herpes simplex virus thymidine kinase gene. Cancer Res 1994; 54: 5408-5413.
    • (1994) Cancer Res , vol.54 , pp. 5408-5413
    • Manome, Y.1
  • 13
    • 0026720075 scopus 로고
    • Tight control of gene expression in transgenic mice by tetracyline-responsive promoters
    • Gossen M, Bujard H. Tight control of gene expression in transgenic mice by tetracyline-responsive promoters. Proc Natl Acad Sci USA 1992; 89: 5547-5551.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 5547-5551
    • Gossen, M.1    Bujard, H.2
  • 14
    • 0027965067 scopus 로고
    • A regulatory system for use in gene transfer
    • Wang Y et al. A regulatory system for use in gene transfer. Proc Natl Acad Sci USA 1994; 91: 8180-8184.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 8180-8184
    • Wang, Y.1
  • 15
    • 0033582216 scopus 로고    scopus 로고
    • Adenovirus-mediated regulable target gene expression in vivo
    • Burcin MM et al. Adenovirus-mediated regulable target gene expression in vivo. Proc Natl Acad Sci USA 1999; 2: 355-360.
    • (1999) Proc Natl Acad Sci USA , vol.2 , pp. 355-360
    • Burcin, M.M.1
  • 16
    • 0027963649 scopus 로고
    • Gene therapy targeted by radiation preferentially radiosensitizes tumour cells
    • Weichselbaum RR et al. Gene therapy targeted by radiation preferentially radiosensitizes tumour cells. Cancer Res 1994; 54: 4266-4269.
    • (1994) Cancer Res , vol.54 , pp. 4266-4269
    • Weichselbaum, R.R.1
  • 17
    • 0029159918 scopus 로고
    • Spatial and temporal control of gene therapy using ionising radiation
    • Hallahan DE et al. Spatial and temporal control of gene therapy using ionising radiation. Nature Med 1995; 8: 786-791.
    • (1995) Nature Med , vol.8 , pp. 786-791
    • Hallahan, D.E.1
  • 18
    • 0032126019 scopus 로고    scopus 로고
    • Transgene expression in malignant glioma using a replication-defective adenoviral vector containing the EGR-1 promoter: Activation by ionizing radiation or uptake of radioactive iododeoxyuridine
    • Manome Y et al. Transgene expression in malignant glioma using a replication-defective adenoviral vector containing the EGR-1 promoter: activation by ionizing radiation or uptake of radioactive iododeoxyuridine. Hum Gene Ther 1998; 9: 1409-1417.
    • (1998) Hum Gene Ther , vol.9 , pp. 1409-1417
    • Manome, Y.1
  • 19
    • 0027587414 scopus 로고
    • The induction of gene expression in mammalian cells by radiation
    • Keyse SM. The induction of gene expression in mammalian cells by radiation. Semin Cancer Biol 1993; 4: 119-128.
    • (1993) Semin Cancer Biol , vol.4 , pp. 119-128
    • Keyse, S.M.1
  • 20
    • 0027359827 scopus 로고
    • WAF1, a potential mediator of p53 tumour suppression
    • El -Deiry SW et al. WAF1, a potential mediator of p53 tumour suppression. Cell 1993; 75: 817-825.
    • (1993) Cell , vol.75 , pp. 817-825
    • El -Diery, S.W.1
  • 21
    • 0029942290 scopus 로고    scopus 로고
    • Induction of p53 and p21/WAF1/CIP1 expression by nitric oxide and their association with apoptosis in human cancer cells
    • Ho YS, Wang YJ, Lin JK. Induction of p53 and p21/WAF1/CIP1 expression by nitric oxide and their association with apoptosis in human cancer cells. Mol Carcinog 1996; 16: 20-31.
    • (1996) Mol Carcinog , vol.16 , pp. 20-31
    • Ho, Y.S.1    Wang, Y.J.2    Lin, J.K.3
  • 22
    • 0030996011 scopus 로고    scopus 로고
    • Progress in transcriptionally targeted and regulable vectors for genetic therapy
    • Miller N, Whelan J. Progress in transcriptionally targeted and regulable vectors for genetic therapy. Hum Gene Ther 1997; 8: 803-815.
    • (1997) Hum Gene Ther , vol.8 , pp. 803-815
    • Miller, N.1    Whelan, J.2
  • 23
    • 0032890124 scopus 로고    scopus 로고
    • Cyclic GMP-independent mechanisms of nitric oxide induced vasodilation
    • Goud C et al. Cyclic GMP-independent mechanisms of nitric oxide induced vasodilation. Gen Pharmacol 1999; 1: 51-55.
    • (1999) Gen Pharmacol , vol.1 , pp. 51-55
    • Goud, C.1
  • 24
    • 0029618106 scopus 로고
    • Expression of human inducible NO synthase in a tetrahydrobiopterin-deficient cell line: Tetrahydrobiopterin promotes assembly of enzyme subunits into an active dimer
    • Tzeng E et al. Expression of human inducible NO synthase in a tetrahydrobiopterin-deficient cell line: tetrahydrobiopterin promotes assembly of enzyme subunits into an active dimer. Proc Natl Acad Sci USA 1995; 92: 11771-11775.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 11771-11775
    • Tzeng, E.1
  • 25
    • 0027992219 scopus 로고
    • Simulation of the diffusion and reaction of endogenously produced nitric oxide
    • Lancaster Jr JR. Simulation of the diffusion and reaction of endogenously produced nitric oxide. Proc Natl Acad Sci USA 1994; 91: 8137-8141.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 8137-8141
    • Lancaster J.R., Jr.1
  • 26
    • 0029753229 scopus 로고    scopus 로고
    • Vascular gene transfer of the human iNOS: Characterisation of activity and effects on myointimal hyperplasia
    • Tzeng E et al. Vascular gene transfer of the human iNOS: characterisation of activity and effects on myointimal hyperplasia. Mol Med 1996; 2: 211-225.
    • (1996) Mol Med , vol.2 , pp. 211-225
    • Tzeng, E.1
  • 27
    • 0029054994 scopus 로고
    • AQ4N: An alkylaminoanthraquinone N-oxide showing bioreductive potential and positive interaction with radiation in vivo
    • McKeown SR et al. AQ4N: an alkylaminoanthraquinone N-oxide showing bioreductive potential and positive interaction with radiation in vivo. Br J Cancer 1995; 72: 76-81.
    • (1995) Br J Cancer , vol.72 , pp. 76-81
    • McKeown, S.R.1
  • 28
    • 0028880451 scopus 로고
    • A novel promoter for vascular endothelial growth factor receptor (flt-1) that confers endothelial-specific gene expression
    • Morishita K, Johnson DE, Williams LT. A novel promoter for vascular endothelial growth factor receptor (flt-1) that confers endothelial-specific gene expression. J Biol Chem 1995; 270: 27948-27953.
    • (1995) J Biol Chem , vol.270 , pp. 27948-27953
    • Morishita, K.1    Johnson, D.E.2    Williams, L.T.3
  • 29
    • 0026677532 scopus 로고
    • HMEC-1 - Establishment of an immortalised human microvascular endothelial cell line
    • Andes EW et al. HMEC-1 - establishment of an immortalised human microvascular endothelial cell line. J Invest Dermatol 1992; 99: 683-690.
    • (1992) J Invest Dermatol , vol.99 , pp. 683-690
    • Andes, E.W.1
  • 30
    • 0028219105 scopus 로고
    • Upstream modification of vasoconstrictor responses in rat epigastric artery supplying an implanted tumour
    • Hirst DG et al. Upstream modification of vasoconstrictor responses in rat epigastric artery supplying an implanted tumour. Adv Exp Mod Biol 1994; 345: 411-416.
    • (1994) Adv Exp Mod Biol , vol.345 , pp. 411-416
    • Hirst, D.G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.