Tumour cell radiosensitization using constitutive (CMV) and radiation inducible (WAF1) promoters to drive the iNOS gene: A novel suicide gene therapy

Gene Therapy

Volumn 9, Issue 4, 2002, Pages 263-269

  Worthington, J ^a   Robson, T ^a   O'keeffe M ^a   Hirst, D G ^a  

^a UNIVERSITY OF ULSTER   (United Kingdom)

Author keywords

Cancer gene therapy; Inducible nitric oxide synthase; Radiosensitization

Indexed keywords

ANGIOGENESIS INHIBITOR; COMPLEMENTARY DNA; N(G) METHYLARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; PROTEIN P21;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER GROWTH; CANCER RADIOTHERAPY; CANCER THERAPY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOMEGALOVIRUS; CYTOTOXICITY; GENE CONSTRUCT; GENE TRANSFER; GENETIC TRANSFECTION; HYPOXIA; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; RADIATION DOSE; RADIOSENSITIVITY; RADIOSENSITIZATION; SUICIDE GENE THERAPY; TUMOR CELL; VIRAL GENE DELIVERY SYSTEM; X RAY;

ANIMALS; APOPTOSIS; CELL DIVISION; CELL SURVIVAL; COMBINED MODALITY THERAPY; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; FEMALE; FIBROSARCOMA; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; MICE; MICE, INBRED C3H; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; PROMOTER REGIONS (GENETICS); RADIATION-SENSITIZING AGENTS; TRANSFECTION; TUMOR CELLS, CULTURED;

ANIMALIA; CYTOMEGALOVIRUS; MURINAE;

EID: 85047697705     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301609     Document Type: Article

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