Presenilin expression during induced differentiation of the human neuroblastoma SH-SY5Y cell line

Neurochemistry International

Volumn 44, Issue 7, 2004, Pages 487-496

  Flood, Fiona ^a   Sundström, Erik ^a   Samuelsson, Eva Britt ^a   Wiehager, Birgitta ^a   Seiger, Åke ^a   Johnston, Janet A ^a   Cowburn, Richard F ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Alzheimer's disease; Differentiation; Neuroblastoma; Presenilin; Retinoic acid

Indexed keywords

CYCLOHEXIMIDE; PHORBOL ESTER; PRESENILIN 1; PRESENILIN 2; PROTEIN SYNTHESIS INHIBITOR; RETINOIC ACID;

ALZHEIMER DISEASE; ARTICLE; BRAIN REGION; CELLULAR DISTRIBUTION; CHOLINERGIC ACTIVITY; CONTROLLED STUDY; CYTOPATHOLOGY; FETUS; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM DEVELOPMENT; NEUROBLASTOMA CELL; NEUROPATHOLOGY; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS INHIBITION; TISSUE DISTRIBUTION;

EID: 0842267118     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuint.2003.09.002     Document Type: Article

References (39)

1. Artavanis-Tsakonas S., Delidakis C., Fehon R.D.H., Herndon V., Johansen K., Markopoulou K., Preiss A., Rebay I., Scottgale N. Notch and the molecular genetics of neuroblast segregation in Drosophila. Mol. Reprod. Dev. 27:1990;23-27.
2. Berezovska O., Frosch M., McLean P., Knowles R., Koo E., Kang D., Shen J., Lu F.M., Lux S.E., Tonegawa S., Hyman B.T. Developmental regulation of presenilin mRNA expression parallels notch expression. J. Neuropathol. Exp. Neurol. 56:1997;40-44.
3. Capell A., Saffrich R., Olivo J.C., Meyn L., Walter J., Grunberg J., Mathews P., Nixon R., Dotti C., Haass C. Cellular expression and proteolytic processing of presenilin proteins is developmentally regulated during neuronal differentiation. J. Neurochem. 69:1997;2432-2440.
4. Capell A., Grunberg J., Pesold B., Diehlmann A., Citron M., Nixon R., Beyreuther K., Selkoe D.J., Haass C. The proteolytic fragments of the Alzheimer's disease-associated presenilin 1 form heterodimers and occur as a 100-150-kDa molecular mass complex. J. Biol. Chem. 273:1998;3205-3211.
5. Counts S.E., Lah J.J., Levey A.I. The regulation of presenilin 1 by nerve growth factor. J. Neurochem. 76:2001;679-689.
6. Culvenor J.G., Evin G., Cooney M.A., Wardan H., Sharples R.A., Maher F., Reed G., Diehlmann A., Weidemann A., Beyreuther K., Masters C.L. Presenilin 2 expression in neuronal cells: induction during differentiation of embryonic carcinoma cells. Exp. Cell Res. 255:2000;192-206.
7. Davis J.A., Naruse S., Chen H., Eckman C., Younkin S., Price D.L., Borchelt D.R., Sisodia S.S., Wong P.C. An Alzheimer's disease-linked PS1 variant rescues the developmental abnormalities of PS1-deficient embryos. Neuron. 20:1998;603-609.
8. De Strooper B., Beullens M., Contreras B., Levesque L., Craessaerts K., Cordell B., Moechars D., Bollen M., Fraser P., George-Hyslop P.S., Van Leuven F. Phosphorylation, subcellular localization, and membrane orientation of the Alzheimer's disease-associated presenilins. J. Biol. Chem. 272:1997;3590-3598.
9. De Strooper B., Saftig P., Craessaerts K., Vanderstichele H., Guhde G., Annaert W., Von Figura K., Van Leuven F. Deficiency of presenilin 1 inhibits the normal cleavage of amyloid precursor protein. Nature. 391:1998;387-390.
10. De Strooper B., Annaert W., Cupers P., Saftig P., Craessaerts K., Mumm J.S., Schroeter E.H., Schrijvers V., Wolfe M.S., Ray W.J., Goate A., Kopan R. A presenilin 1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain. Nature. 398:1999;518-522.
11. Dowjat W.K., Wisniewski T., Efthimiopoulos S., Wisniewski H.M. Inhibition of neurite outgrowth by familial Alzheimer's disease-linked presenilin 1 mutations. Neurosci. Lett. 267:1999;141-144.
12. Fraser P.E., Levesque G., Yu G., Mills L.R., Thirlwell J., Frantseva M., Gandy S.E., Seeger M., Carlen P.L., St George-Hyslop P. Presenilin 1 is actively degraded by the 26S proteasome. Neurobiol. Aging. 19:1998;S19-21.
13. Furukawa K., Guo Q., Schellenberg G.D., Mattson M.P. Presenilin 1 mutation alters NGF-induced neurite outgrowth, calcium homeostasis, and transcription factor (AP-1) activation in PC12 cells. J. Neurosci. Res. 52:1998;618-624.
14. Haass C., De Strooper B. The presenilins in Alzheimer's disease-proteolysis holds the key. Science. 286:1999;916-919.
15. Hardy J. Amyloid, the presenilins and Alzheimer's disease. Trends Neurosci. 20:1997;154-159.
16. Hong C.S., Caromile L., Nomata Y., Mori H., Bredesen D.E., Koo E.H. Contrasting role of presenilin 1 and 2 in neuronal differentiation in vitro. J. Neurosci. 19:1999;637-643.
17. Ishii K., Ii K., Hasegawa T., Shoji S., Doi A., Mori H. Increased a beta 42(43)-plaque deposition in early-onset familial Alzheimer's disease brains with the deletion of exon-9 and the missense point mutation (H163R) in the PS-1 gene. Neurosci. Lett. 228:1997;17-20.
18. Jeong S.J., Kim H.S., Chang K.A., Geum D.H., Park C.H., Seo J.H., Rah J.C., Lee J.H., Choi S.H., Lee S.G., Kim K., Suh Y.H. Subcellular localization of presenilins during mouse pre-implantation development. FASEB J. 14:2000;2171-2176.
19. Kopan R., Schroeter E.H., Weintraub H., Nye J.S. Signal transduction by activated mNotch: importance of proteolytic processing and its regulation by the extracellular domain. Proc. Natl. Acad. Sci. U.S.A. 93:1996;1683-1688.
20. Kostyszyn B., Cowburn R.F., Seiger Å., Kjældgaard A., Sundström E. Expression of presenilin 1 and Notch-1 receptor in human embryonic CNS. Neuroscience. 103:2001;885-898.
21. Li J., Xu M., Zhou H., Ma J., Potter H. Alzheimer presenilins in the nuclear membrane, interphase kinetochores, and centrosomes suggest a role in chromosome segregation. Cell. 90:1997;917-927.
22. Mehta N.D., Refolo L.M., Eckman C., Sanders S., Yager D., Perez-Tur J., Younkin S., Duff K., Hardy J., Hutton M. Increased Abeta42(43) from cell lines expressing presenilin 1 mutations. Ann. Neurol. 43:1998;256-258.
23. Pastorcic M., Das H.K. Activation of transcription of the human presenilin 1 gene by 12-O-tetradecanoylphorbol-13-acetate. Eur. J. Biochem. 269:2002;5956-5962.
24. Påhlman S., Odelstad L., Larsson E., Grotte G., Nilsson K. Phenotypic changes of human neuroblastoma cells in culture induced by 12-O-tetradecanoylphorbol-13-acetate. Int. J. Cancer. 28:1981;583-589.
25. Påhlman S., Ruusala A.I., Abrahamsson L., Mattsson M.E.K., Esscher T. Retinoic acid-induced differentiation of cultured human neuroblastoma cells: a comparison with phorbolester-induced differentiation. Cell Differ. 14:1984;135-144.
26. Perez-Tur J., Froehlich S., Prihar G., Crook R., Baker M., Duff K., Wragg M., Busfield F., Lendon C., Clark R.F., Roques P., Fuldner R.A., Johnston J., Cowburn R.F., Forsell C., Axelman K., Lilius L., Houlden H., Karran R., Roberts G.W., Rossor M., Adams M.D., Hardy J., Goate A., Lannfelt L., Hutton M. A mutation in Alzheimer's disease destroying a splice acceptor site in the presenilin 1 gene. Neuroreport. 7:1995;297-301.
27. Podlisny M.B., Citron M., Amarante P., Sherrington R., Xia W., Zhang J., Diehl T., Levesque G., Fraser P., Haass C., Koo E.H., Seubert P., St George-Hyslop P., Teplow D.B., Selkoe D.J. Presenilin proteins undergo heterogeneous endoproteolysis between Thr291 and Ala299 and occur as stable N- and C-terminal fragments in normal and Alzheimer brain tissue. Neurobiol. Dis. 3:1997;325-337.
28. Qian S., Jiang P., Guan X.M., Singh G., Trumbauer M.E., Yu H., Chen H.Y., Van de Ploeg L.H., Zheng H. Mutant human presenilin 1 protects presenilin 1 null mouse against embryonic lethality and elevates Abeta1-42/43 expression. Neuron. 20:1998;611-617.
29. Ratovitski T., Slunt H.H., Thinakaran G., Price D.L., Sisodia S.S., Borchelt D.R. Endoproteolytic processing and stabilization of wild-type and mutant presenilin. J. Biol. Chem. 272:1997;24536-24541.
30. Rogaev E.I., Sherrington R., Rogaeva E.A., Levesque G., Ikeda M., Liang Y., Chi H., Lin C., Holman K., Tsuda T.et al. Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene. Nature. 376:1995;775-778.
31. Selkoe D. Alzheimer's disease: genes, proteins, and therapy. Physiol. Rev. 81:2001;741-766.
32. Shen J., Bronson R.T., Chen D.F., Xia W., Selkoe D.J., Tonegawa S. Skeletal and CNS defects in presenilin-1-deficient mice. Cell. 89:1997;629-639.
33. Sherrington R., Froelich S., Sorbi S., Campion D., Chi H., Rogaeva E.A., Levesque G., Rogaev E.I., Lin C., Liang Y., Ikeda M., Mar L., Brice A., Agid Y., Percy M.E., Clerget-Darpoux F., Piacentini S., Marcon G., Nacmias B., Amaducci L., Frebourg T., Lannfelt L., Rommens J.M., St George-Hyslop P.H. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. Nature. 375:1995;754-760.
34. Song W., Nadeau P., Yuan M., Yang X., Shen J., Yankner B.A. Proteolytic release and nuclear translocation of Notch-1 are induced by presenilin 1 and impaired by pathogenic presenilin 1 mutations. Proc. Natl. Acad. Sci. U.S.A. 96:1999;6959-6963.
35. Tanii H., Ankarcrona M., Flood F., Nilsberth C., Mehta N.D., Perez-Tur J., Winblad B., Benedikz E., Cowburn R.F. Alzheimer's disease presenilin 1 exon-9 deletion and L250S mutations sensitize SH-SY5Y neuroblastoma cells to hyperosmotic stress-induced apoptosis. Neuroscience. 95:2000;593-601.
36. Thinakaran G., Borchelt D.R., Lee M.K., Slunt H.H., Spitzer L., Kim G., Ratovitsky T., Davenport F., Nordstedt C., Seeger M., Hardy J., Levey A.I., Gandy S.E., Jenkins N.A., Copeland N.G., Price D.L., Sisodia S.S. Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo. Neuron. 17:1996;181-190.
37. Thinakaran G., Harris C.L., Ratovitski T., Davenport F., Slunt H.H., Price D.L., Borchelt D.R., Sisodia S.S. Evidence that levels of presenilins (PS1 and PS2) are coordinately regulated by competition for limiting cellular factors. J. Biol. Chem. 272:1997;28415-28422.
38. Tokuhiro S., Tomita T., Iwata H., Kosaka T., Saido T.C., Maruyama K., Iwatsubo T. The presenilin 1 mutation (M146V) linked to familial Alzheimer's disease attenuates the neuronal differentiation of NTera 2 cells. Biochem. Biophys. Res. Commun. 244:1998;751-755.
39. Wong P.C., Zheng H., Chen H., Becher M.W., Sirinathsinghji D.J., Trumbauer M.E., Chen H.Y., Price D.L., Van der Ploeg L.H., Sisodia S.S. Presenilin 1 is required for Notch1 and DII1 expression in the paraxial mesoderm. Nature. 387:1997;288-292.