Peutz-Jeghers families unlinked to STK11/LKB1 gene mutations are highly predisposed to primitive biliary adenocarcinoma

Journal of Medical Genetics

Volumn 38, Issue 6, 2001, Pages 356-360

  Olschwang, S ^a   Boisson, C ^a   Thomas, G ^a,b,c  

^a INSERM   (France)

^b FONDATION JEAN DAUSSET CEPH   (France)

^c HÔPITAL SAINT ANTOINE   (France)

Author keywords

Cancer predisposition; Genetic heterogeneity; Peutz Jeghers disease; Risk estimation

Indexed keywords

ADENOCARCINOMA; ARTICLE; BILE DUCT CARCINOMA; CANCER RISK; CHILD; CLINICAL ARTICLE; GENE MUTATION; GENETIC COUNSELING; GENETIC LINKAGE; GENETIC PREDISPOSITION; HUMAN; INFANT; PEUTZ JEGHERS SYNDROME; PRIORITY JOURNAL;

EID: 0034988818     PISSN: 00222593     EISSN: None     Source Type: Journal    
DOI: 10.1136/jmg.38.6.356     Document Type: Article

References (16)

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5. Genetic pathways of colorectal carcinogenesis rarely involve the PTEN and LKB1 genes outside the inherited hamartoma syndromes
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13. Peutz-Jeghers disease: Most, but not all, families are compatible with linkage to 19p13.3
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15. The molecular basis and clinical aspects of Peutz-Jeghers syndrome
16. PTEN mutation spectrum and genotype-phenotype correlations in Bannayan-Riley-Ruvalcaba syndrome suggest a single entity with Cowden syndrome