The uvsI gene of Aspergillus nidulans required for UV-mutagenesis encodes a homolog to REV3, a subunit of the DNA polymerase ζ of yeast involved in translesion DNA synthesis

FEMS Microbiology Letters

Volumn 164, Issue 1, 1998, Pages 13-19

  Han, Kyu Yong ^a   Chae, Suhn Kee ^b   Han, Dong Min ^a  

^a Wonkwang University   (South Korea)

^b PaiChai University   (South Korea)

Author keywords

Aspergillus nidulans; DNA polymerase; DNA repair; Rev3; UvsI

Indexed keywords

ALLELISM; AMINO ACID SEQUENCE; ARTICLE; ASPERGILLUS NIDULANS; DNA LIBRARY; EXCISION REPAIR; GENE LOCATION; GENE TARGETING; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; RADIATION MUTAGENESIS; RADIOSENSITIVITY; REVERTANT; SEQUENCE ANALYSIS;

AMINO ACID SEQUENCE; ASPERGILLUS NIDULANS; DNA POLYMERASE BETA; DNA, FUNGAL; DNA-DIRECTED DNA POLYMERASE; FUNGAL PROTEINS; GENES, FUNGAL; MOLECULAR SEQUENCE DATA; MUTAGENESIS; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; ULTRAVIOLET RAYS;

ASPERGILLUS; EMERICELLA NIDULANS;

EID: 0032125227     PISSN: 03781097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1097(98)00185-2     Document Type: Article

References (28)

1. Chae, S.-K. and Kafer, E. (1993) uvsI mutants defective in UV mutagenesis define a fourth epistatic group of uvs genes in Aspergillus. Curr. Genet. 24, 67-74.
2. Kafer, E. and Mayor, O. (1986) Genetic analysis of DNA repair in Aspergillus: evidence for different types of MMS-sensitive hyper-rec mutants. Mutat. Res. 161, 119-134.
3. Yoon, J.-H., Lee, B.-J. and Kang, H.-S. (1995) The Aspergillus uvsH gene encodes a homolog to yeast RAD18 and Neurospora uvs-2. Mol. Gen. Genet. 248, 174-181.
4. Kafer, E. and May, G. (1997) The uvsF gene region in Aspergillus nidulans codes for a protein with homology to DNA replication factor C. Gene 191, 155-159.
5. Jansen, G.J.O. (1970) Survival of uvsB and uvsC mutants of Aspergillus nidulans after UV irradiation. Mutat. Res. 10, 21-32.
6. Kafer, E. and Chae, S.-K. (1994) Phenotypic and epistatic grouping of hypo- and hyper-rec mus mutants in Aspergillus. Curr. Genet. 25, 223-232.
7. Jansen, G.J.O. (1970) Abnormal frequencies of spontaneous mitotic recombination in uvsB and uvsC mutants of Aspergillus nidulans. Mutat. Res. 10, 33-41.
8. Seong, K.Y., Chae, S.-K. and Kang, H.-S. (1997) Cloning of an E. coli RecA and yeast RAD51 homolog, radA, an allele of the uvsC in Aspergillus nidulans and its mutator effects. Mol. Cells 7, 284-289.
9. van Heemst, D., Swart, K., Holub, E.F., van Dijk, R., Offenberg, H.H., Goosen, T., van den Broek, H.W.J. and Heyting, C. (1997) Cloning, sequencing, disruption and phenotypic analysis of UVSC, an Aspergillus nidulans homologue of yeast RAD51. Mol. Gen. Genet. 254, 654-664.
10. Jansen, G.J.O. (1972) Mutator activity in uvs mutants of Aspergillus nidulans. Mol. Gen. Genet. 116, 47-50.
11. Chae, S.-K. and Kafer, E. (1997) Two uvs genes of Aspergillus nidulans with different functions in error-prone repair: uvsI, active in mutation-specific reversion, and uvsC, a recA homolog, required for all UV mutagenesis. Mol. Gen. Genet. 254, 643-653.
12. Han, D.-M. and Kang, H.-S. (1985) A study on the error prone DNA repair in Aspergillus nidulans: cell lethality and mutation induced by UV radiation in germinating asexual spores. Korean J. Env. Mut. Carcin. 52, 53-60.
13. Han, D.-M., Suh, H.Y., Choi, K.H. and Kang, H.-S. (1983) Isolation and characterization of UV-sensitive mutants in Aspergillus nidulans. Korean J. Env. Mut. Carcin. 31, 21-33.
14. Kafer, E. (1977) Meiotic and mitotic recombination in Aspergillus and its chromosomal aberrations. Adv. Genet. 19, 33-131.
15. Pontecorvo, G., Roper, J.A., Hemmons, L.M., Macdonald, K.D. and Bufton, A.J.W. (1953) The genetics of Aspergillus nidulans. Adv. Genet. 5, 141-238.
16. Sambrook, J., Fritsch, E.F. and Maniatis, T. (1992) Molecular Cloning: A Laboratory Manual, 2nd Edn. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
17. Brody, H., Griffith, J., Cuticchia, A.J., Arnold, J. and Timberlake, W.E. (1991) Chromosome-specific recombinant DNA libraries from the fungus Aspergillus nidulans. Nucleic Acids Res. 19, 3105-3109.
18. Johnston, I.L., Huges, S.G. and Clutterbuck, A.J. (1985) Cloning of an Aspergillus nidulans developmental gene by transformation. EMBO J. 4, 1307-1311.
19. Yelton, M.M., Hammer, J.E. and Timberlake, W.E. (1984) Transformation of Aspergillus nidulans by using a trpC plasmid. Proc. Natl. Acad. Sci. USA 81, 1470-1474.
20. Wieser, J. and Adams, T.H. (1995) filD encodes a Myb-like DNA-binding protein that coordinates initiation of Aspergillus nidulans conidiophore development. Genes Dev. 9, 491-502.
21. Morrison, A., Christensen, R.B., Alley, J., Beck, A.K., Bernstine, E.G., Lemontt, J.F. and Lawrence, C.W. (1989) REV3, a Saccharomyces cerevisiae gene whose function is required for induced mutagenesis, is predicted to encode a nonessential DNA polymerase. J. Bacteriol. 171, 5659-5667.
22. Nelson, J.R., Lawrence, C.W. and Hinkle, D.C. (1996) Thymine-thymine dimer bypass by yeast DNA polymerase ζ. Science 272, 1646-1649.
23. Wong, S.W., Wahl, A.F., Yuan, P.-M., Arai, N.A., Pearson, B.E., Arai, K.-I., Korn, D., Hunkapiller, M.W. and Wang, T.S.-F. (1988) Human DNA polymerase α gene expression is cell proliferation dependent and its primary structure is similar to both prokaryotic and eukaryotic replicative DNA polymerases. EMBO J. 7, 37-47.
24. Lemontt, J.F. (1971) Mutations of yeast defective in mutation induced by ultraviolet light. Genetics 195, 487-490.
25. Lawrence, C.W. and Christensen, R.B. (1979) Ultraviolet-induced reversion of cyc1 alleles in radiation-sensitive strains of yeast. III. rev3 mutant strains. Genetics 92, 397-408.
26. Lawrence, C.W. (1982) Mutagenesis in Saccharomyces cerevisiae. Adv. Genet. 21, 173-254.
27. Baynton, K., Bresson-Roy, A. and Fuchs, R.P. (1998) Analysis of damage tolerance pathways in Saccharomyces cerevisiae: a requirement for Rev3p DNA polymerase in translesion synthesis. Mol. Cell Biol. 18, 960-966.
28. Kafer, E. and May, G. (1998) Toward repair pathways in Aspergillus nidulans. In: DNA Damage and Repair (Nickoloff, J.A. and Hoekstra, M.F., Eds.), Vol. 1, pp. 477-502. Humana Press, Totawa, NJ.