메뉴 건너뛰기




Volumn 60, Issue 2, 2003, Pages 137-151

Glutamate receptor genes as candidates for schizophrenia susceptibility

Author keywords

Antipsychotic drug; Association study; Endophenotype; Gene manipulated mice; Glutamate receptor; GRIA4; GRIK1; GRIK2; GRIN1; GRM2; GRM3; Haplotype; Linkage disequilibrium (LD); Schizophrenia; SNP

Indexed keywords

AMPA RECEPTOR; CLOZAPINE; DECAHYDRO 6 [2 (1H TETRAZOL 5 YL)ETHYL] 3 ISOQUINOLINECARBOXYLIC ACID; EGLUMETAD; GLUTAMATE RECEPTOR; HALOPERIDOL; IONOTROPIC RECEPTOR; KAINIC ACID RECEPTOR; KETAMINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PHENCYCLIDINE;

EID: 0141997717     PISSN: 02724391     EISSN: None     Source Type: Journal    
DOI: 10.1002/ddr.10293     Document Type: Review
Times cited : (7)

References (93)
  • 3
    • 0028916869 scopus 로고
    • Functional analysis of the proximal 5′-flanking region of the N-methyl-D-aspartate receptor subunit gene, NMDAR1
    • Bai G, Kusiak JW. 1995. Functional analysis of the proximal 5′-flanking region of the N-methyl-D-aspartate receptor subunit gene, NMDAR1. J Biol Chem 270:7737-7744.
    • (1995) J Biol Chem , vol.270 , pp. 7737-7744
    • Bai, G.1    Kusiak, J.W.2
  • 4
    • 0036261211 scopus 로고    scopus 로고
    • Association between the ionotropic glutamate receptor kainate 3 (GRIK3) ser310ala polymorphism and schizophrenia
    • Begni S, Popoli M, Moraschi S, Bignotti S, Tura GB, Gennarelli M. 2002 Association between the ionotropic glutamate receptor kainate 3 (GRIK3) ser310ala polymorphism and schizophrenia. Mol Psychiatry 7:416-418.
    • (2002) Mol Psychiatry , vol.7 , pp. 416-418
    • Begni, S.1    Popoli, M.2    Moraschi, S.3    Bignotti, S.4    Tura, G.B.5    Gennarelli, M.6
  • 5
    • 0035079771 scopus 로고    scopus 로고
    • Glutamate and its role in psychiatric illness
    • Belsham B. 2001. Glutamate and its role in psychiatric illness. Hum Psychopharmacol 16:139-146.
    • (2001) Hum Psychopharmacol , vol.16 , pp. 139-146
    • Belsham, B.1
  • 6
    • 0034747123 scopus 로고    scopus 로고
    • GluR5,6,7 subunit immunoreactivity on apical pyramidal cell dendrites in hippocampus of schizophrenics and manic depressives
    • Benes FM, Todtenkopf MS, Kostoulakos P. 2001. GluR5,6,7 subunit immunoreactivity on apical pyramidal cell dendrites in hippocampus of schizophrenics and manic depressives. Hippocampus 11:482-491.
    • (2001) Hippocampus , vol.11 , pp. 482-491
    • Benes, F.M.1    Todtenkopf, M.S.2    Kostoulakos, P.3
  • 8
    • 0035863275 scopus 로고    scopus 로고
    • Polymorphisms in the genes for mGluR types 7 and 8: Association studies with schizophrenia
    • Bolonna AA, Kerwin RW, Munro J, Arranz MJ, Makoff AJ. 2001. Polymorphisms in the genes for mGluR types 7 and 8: association studies with schizophrenia. Schizophr Res 47:99-103.
    • (2001) Schizophr Res , vol.47 , pp. 99-103
    • Bolonna, A.A.1    Kerwin, R.W.2    Munro, J.3    Arranz, M.J.4    Makoff, A.J.5
  • 10
    • 0028928362 scopus 로고
    • Glutamate receptor subtype expression in human postmortem brain tissue from schizophrenics and alcohol abusers
    • Breese CR, Freedman R, Leonard SS. 1995. Glutamate receptor subtype expression in human postmortem brain tissue from schizophrenics and alcohol abusers. Brain Res 674:82-90.
    • (1995) Brain Res , vol.674 , pp. 82-90
    • Breese, C.R.1    Freedman, R.2    Leonard, S.S.3
  • 11
    • 0033844601 scopus 로고    scopus 로고
    • Regulation of neurotransmitter release by metabotropic glutamate receptors
    • Cartmell J, Schoepp DD. 2000. Regulation of neurotransmitter release by metabotropic glutamate receptors. Neurochemistry 75:889-907.
    • (2000) Neurochemistry , vol.75 , pp. 889-907
    • Cartmell, J.1    Schoepp, D.D.2
  • 12
    • 0034731587 scopus 로고    scopus 로고
    • Dopamine and 5-HT turnover are increased by the mGlu2/3 receptor agonist LY379268 in rat medial prefrontal cortex, nucleus accumbens and striatum
    • Cartmell J, Salhoff CR, Perry KW, Monn JA, Schoepp DD. 2000. Dopamine and 5-HT turnover are increased by the mGlu2/3 receptor agonist LY379268 in rat medial prefrontal cortex, nucleus accumbens and striatum. Brain Res 887:378-384.
    • (2000) Brain Res , vol.887 , pp. 378-384
    • Cartmell, J.1    Salhoff, C.R.2    Perry, K.W.3    Monn, J.A.4    Schoepp, D.D.5
  • 15
    • 0032077288 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor-mediated control of neurotransmitter release
    • Cochilla AJ, Alford S. 1998. Metabotropic glutamate receptor-mediated control of neurotransmitter release. Neuron 20:1007-1016.
    • (1998) Neuron , vol.20 , pp. 1007-1016
    • Cochilla, A.J.1    Alford, S.2
  • 16
    • 0036176446 scopus 로고    scopus 로고
    • Comparative analysis of group II metabotropic glutamate receptor immunoreactivity in Brodmann's area 46 of the dorsolateral prefrontal cortex from patients with schizophrenia and normal subjects
    • Crook JM, Akil M, Law BC, Hyde TM, Kleinman JE. 2002. Comparative analysis of group II metabotropic glutamate receptor immunoreactivity in Brodmann's area 46 of the dorsolateral prefrontal cortex from patients with schizophrenia and normal subjects. Mol Psychiat 7:157-164.
    • (2002) Mol Psychiat , vol.7 , pp. 157-164
    • Crook, J.M.1    Akil, M.2    Law, B.C.3    Hyde, T.M.4    Kleinman, J.E.5
  • 18
    • 0028907468 scopus 로고
    • Decreased expression of mRNAs encoding non-NMDA glutamate receptors GluR1 and GluR2 in medial temporal lobe neurons in schizophrenia
    • Eastwood SL, McDonald B, Burnet PW, Beckwith JP, Kerwin RW, Harrison PJ. 1995. Decreased expression of mRNAs encoding non-NMDA glutamate receptors GluR1 and GluR2 in medial temporal lobe neurons in schizophrenia. Brain Res Mol Brain Res 29:211-223.
    • (1995) Brain Res Mol Brain Res , vol.29 , pp. 211-223
    • Eastwood, S.L.1    McDonald, B.2    Burnet, P.W.3    Beckwith, J.P.4    Kerwin, R.W.5    Harrison, P.J.6
  • 19
    • 0031017606 scopus 로고    scopus 로고
    • GluB2 glutamate receptor subunit flip and flop isoforms are decreased in the hippocampal formation in schizophrenia: A reverse transcriptase-polymerase chain reaction (RT-PCR) study
    • Eastwood SL, Burnet PW, Harrison PJ. 1997a, GluB2 glutamate receptor subunit flip and flop isoforms are decreased in the hippocampal formation in schizophrenia: a reverse transcriptase-polymerase chain reaction (RT-PCR) study. Brain Res Mol Brain Res 44:92-98.
    • (1997) Brain Res Mol Brain Res , vol.44 , pp. 92-98
    • Eastwood, S.L.1    Burnet, P.W.2    Harrison, P.J.3
  • 20
    • 0031004644 scopus 로고    scopus 로고
    • Immunoautoradiographic evidence for a loss of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate-preferring non-N-methyl-D-aspartate glutamate receptors within the medial temporal lobe in schizophrenia
    • Eastwood SL, Kerwin RW, Hanison PJ. 1997b. Immunoautoradiographic evidence for a loss of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate-preferring non-N-methyl-D-aspartate glutamate receptors within the medial temporal lobe in schizophrenia. Biol Psychiat 41:636-643.
    • (1997) Biol Psychiat , vol.41 , pp. 636-643
    • Eastwood, S.L.1    Kerwin, R.W.2    Hanison, P.J.3
  • 24
    • 0033914752 scopus 로고    scopus 로고
    • Ionotropic glutamate receptors and expression of N-methyl-D-aspartate receptor subunits in subregions of human hippocampus: Effects of schizophrenia
    • Gao XM, Sakai K, Roberts RC, Conley RR, Dean B, Tamminga CA. 2000. Ionotropic glutamate receptors and expression of N-methyl-D-aspartate receptor subunits in subregions of human hippocampus: effects of schizophrenia. Am J Psychiat 157:1141-1149.
    • (2000) Am J Psychiat , vol.157 , pp. 1141-1149
    • Gao, X.M.1    Sakai, K.2    Roberts, R.C.3    Conley, R.R.4    Dean, B.5    Tamminga, C.A.6
  • 25
    • 0035575503 scopus 로고    scopus 로고
    • Schizophrenia spectrum disorders: An autosomal-wide scan in multiplex pedigrees
    • Garver DL, Holcomb J, Mapua FM, Wilson R, Barnes B. 2001. Schizophrenia spectrum disorders: an autosomal-wide scan in multiplex pedigrees. Schizophr Res 52:145-160.
    • (2001) Schizophr Res , vol.52 , pp. 145-160
    • Garver, D.L.1    Holcomb, J.2    Mapua, F.M.3    Wilson, R.4    Barnes, B.5
  • 27
    • 0027381405 scopus 로고
    • Expression and novel subunit isoforms of glutamate receptor genes GluR5 and GluR6
    • Gregor P, O'Hara BF, Yang X, Uhl GR. 1993. Expression and novel subunit isoforms of glutamate receptor genes GluR5 and GluR6. Neuroreport 4:1343-1346.
    • (1993) Neuroreport , vol.4 , pp. 1343-1346
    • Gregor, P.1    O'Hara, B.F.2    Yang, X.3    Uhl, G.R.4
  • 28
    • 0033601963 scopus 로고    scopus 로고
    • NR2B-containing NMDA receptors are up-regulated in temporal cortex in schizophrenia
    • Grimwood S, Slater P, Deakin JF, Hutson PH. 1999. NR2B-containing NMDA receptors are up-regulated in temporal cortex in schizophrenia. Neuroreport 10:461-465.
    • (1999) Neuroreport , vol.10 , pp. 461-465
    • Grimwood, S.1    Slater, P.2    Deakin, J.F.3    Hutson, P.H.4
  • 29
    • 0025967753 scopus 로고
    • Decreased hippocampal expression of a glutamate receptor gene in schizophrenia
    • Harrison PJ, McLaughlin D, Kerwin RW. 1991. Decreased hippocampal expression of a glutamate receptor gene in schizophrenia. Lancet 337:450-452.
    • (1991) Lancet , vol.337 , pp. 450-452
    • Harrison, P.J.1    McLaughlin, D.2    Kerwin, R.W.3
  • 30
    • 0030023750 scopus 로고    scopus 로고
    • Differential regulation, by MK-801, of dopamine receptor gene expression in rat nigrostriatal and mesocorticolimbic systems
    • Healy DJ, Meador-Woodruff JH. 1996. Differential regulation, by MK-801, of dopamine receptor gene expression in rat nigrostriatal and mesocorticolimbic systems. Brain Res 708:38-44.
    • (1996) Brain Res , vol.708 , pp. 38-44
    • Healy, D.J.1    Meador-Woodruff, J.H.2
  • 31
    • 0030968802 scopus 로고    scopus 로고
    • Clozapine and haloperidol differentially affect AMPA and kainate receptor subunit mRNA levels in rat cortex and striatum
    • Healy DJ, Meador-Woodruff JH. 1997. Clozapine and haloperidol differentially affect AMPA and kainate receptor subunit mRNA levels in rat cortex and striatum. Brain Res Mol Brain Res 47:331-338.
    • (1997) Brain Res Mol Brain Res , vol.47 , pp. 331-338
    • Healy, D.J.1    Meador-Woodruff, J.H.2
  • 33
    • 0026530085 scopus 로고
    • The KA-2 subunit of excitatory amino acid receptors shows widespread expression in brain and forms ion channels with distantly related subunits
    • Herb A, Burnashev N, Werner P, Sakmann B, Wisden W, Seeburg PH. 1992. The KA-2 subunit of excitatory amino acid receptors shows widespread expression in brain and forms ion channels with distantly related subunits. Neuron 8:775-785.
    • (1992) Neuron , vol.8 , pp. 775-785
    • Herb, A.1    Burnashev, N.2    Werner, P.3    Sakmann, B.4    Wisden, W.5    Seeburg, P.H.6
  • 34
    • 0030811980 scopus 로고    scopus 로고
    • Experimental down-regulation of the NMDA channel associated with synapse pruning
    • Hickmott PW, Constantine-Paton M. 1997. Experimental down-regulation of the NMDA channel associated with synapse pruning. J Neurophysiol 78:1096-1107.
    • (1997) J Neurophysiol , vol.78 , pp. 1096-1107
    • Hickmott, P.W.1    Constantine-Paton, M.2
  • 35
    • 0027772363 scopus 로고
    • RNA editing of AMPA receptor subunit GluR-B: A base-paired intron-exon structure determines position and efficiency
    • Higuchi M, Single FN, Kohler M, Sommer B, Sprengel R, Seeburg PH. 1993. RNA editing of AMPA receptor subunit GluR-B: a base-paired intron-exon structure determines position and efficiency. Cell 75:1361-1370.
    • (1993) Cell , vol.75 , pp. 1361-1370
    • Higuchi, M.1    Single, F.N.2    Kohler, M.3    Sommer, B.4    Sprengel, R.5    Seeburg, P.H.6
  • 36
    • 0345059225 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor activation and blockade: Their role in long-term potentiation, learning and neurotoxicity
    • Holscher C, Gigg J, O'Mara SM. 1999. Metabotropic glutamate receptor activation and blockade: their role in long-term potentiation, learning and neurotoxicity. Neurosci Biobehav Rev 23:399-410.
    • (1999) Neurosci Biobehav Rev , vol.23 , pp. 399-410
    • Holscher, C.1    Gigg, J.2    O'Mara, S.M.3
  • 37
    • 0030687458 scopus 로고    scopus 로고
    • Axon-target interactions maintain synaptic gene expression in retinae transplanted to intracranial regions of the rat
    • Hoover F, Hankin MH, Radel JD, Reese JS, Goldman D. 1997. Axon-target interactions maintain synaptic gene expression in retinae transplanted to intracranial regions of the rat. Brain Res Mol Brain Res 51:123-132.
    • (1997) Brain Res Mol Brain Res , vol.51 , pp. 123-132
    • Hoover, F.1    Hankin, M.H.2    Radel, J.D.3    Reese, J.S.4    Goldman, D.5
  • 38
    • 0035703938 scopus 로고    scopus 로고
    • Association analysis for NMDA receptor subunit 2B (GRIN2B) genetic variants and psychopathology and clozapine response in schizophrenia
    • Hong CJ, Yu YW, Lin CH, Cheng CY, Tsai SJ. 2001. Association analysis for NMDA receptor subunit 2B (GRIN2B) genetic variants and psychopathology and clozapine response in schizophrenia. Psychiatr Genet 11:219-222.
    • (2001) Psychiatr Genet , vol.11 , pp. 219-222
    • Hong, C.J.1    Yu, Y.W.2    Lin, C.H.3    Cheng, C.Y.4    Tsai, S.J.5
  • 39
    • 0029910263 scopus 로고    scopus 로고
    • NMDA receptor mRNA correlation with antemortem cognitive impairment in schizophrenia
    • Humphries C, Mortimer A, Hirsch S, de Belleroche J. 1996. NMDA receptor mRNA correlation with antemortem cognitive impairment in schizophrenia. Neuroreport 7:2051-2055.
    • (1996) Neuroreport , vol.7 , pp. 2051-2055
    • Humphries, C.1    Mortimer, A.2    Hirsch, S.3    De Belleroche, J.4
  • 40
    • 0036915223 scopus 로고    scopus 로고
    • 2002 Systematic mutation analysis of the human glutamate receptor, ionotropic, N-methyl-D-aspartate 1 gene(GRIN1) in schizophrenic patients
    • Hung CC, Chen HY, Chen CH. 2002. 2002 Systematic mutation analysis of the human glutamate receptor, ionotropic, N-methyl-D-aspartate 1 gene(GRIN1) in schizophrenic patients. Psychiatr Genet 12:225-230.
    • (2002) Psychiatr Genet , vol.12 , pp. 225-230
    • Hung, C.C.1    Chen, H.Y.2    Chen, C.H.3
  • 43
    • 0025952455 scopus 로고
    • Recent advances in the phencyclidine model of schizophrenia
    • Javitt DC, Zukin SR. 1991. Recent advances in the phencyclidine model of schizophrenia. Am J Psychiat 148:1301-1308.
    • (1991) Am J Psychiat , vol.148 , pp. 1301-1308
    • Javitt, D.C.1    Zukin, S.R.2
  • 44
    • 0035112644 scopus 로고    scopus 로고
    • Structure and polymorphisms of the human metabotropic glutamate receptor type 2 gene (GRM2): Analysis of association with schizophrenia
    • Joo A, Shibata H, Ninomiya H, Kawasaki H, Tashiro N, Fukumaki Y. 2001. Structure and polymorphisms of the human metabotropic glutamate receptor type 2 gene (GRM2): analysis of association with schizophrenia. Mol Psychiat 6:186-192.
    • (2001) Mol Psychiat , vol.6 , pp. 186-192
    • Joo, A.1    Shibata, H.2    Ninomiya, H.3    Kawasaki, H.4    Tashiro, N.5    Fukumaki, Y.6
  • 45
    • 0019293020 scopus 로고
    • Low cerebrospinal fluid glutamate in schizophrenic patients and a new hypothesis on schizophrenia
    • Kim JS, Kornhuber HH, Schmid-Burgk W, Holzmuller B. 1980. Low cerebrospinal fluid glutamate in schizophrenic patients and a new hypothesis on schizophrenia. Neurosci Lett 20: 379-382.
    • (1980) Neurosci Lett , vol.20 , pp. 379-382
    • Kim, J.S.1    Kornhuber, H.H.2    Schmid-Burgk, W.3    Holzmuller, B.4
  • 46
    • 0026080111 scopus 로고
    • A rapid non-enzymatic method for the preparation of HMW DNA from blood for RFLP studies
    • Lahiri DK, Nurnberger JI, Jr. 1991. A rapid non-enzymatic method for the preparation of HMW DNA from blood for RFLP studies. Nucleic Acids Res 19:5444.
    • (1991) Nucleic Acids Res , vol.19 , pp. 5444
    • Lahiri, D.K.1    Nurnberger J.I., Jr.2
  • 49
    • 0030954048 scopus 로고    scopus 로고
    • Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP
    • Lu YM, Jia Z, Janus C, Henderson JT, Gerlai R, Wojtowicz JM, Roder JC. 1997. Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP. Neuroscience 17:5196-5205.
    • (1997) Neuroscience , vol.17 , pp. 5196-5205
    • Lu, Y.M.1    Jia, Z.2    Janus, C.3    Henderson, J.T.4    Gerlai, R.5    Wojtowicz, J.M.6    Roder, J.C.7
  • 50
    • 0042178301 scopus 로고    scopus 로고
    • Positive association of the AMPA receptor subunit GluR4 (GRIA4) haplotype with schizophrenia: Linkage disequilibrium mapping using SNPs evenly distributed across the gene region
    • Makino C, Fujii Y, Kikuta R, Hirata N, Tani A, Shibata A, Ninomiya H, Tashiro N, Shibata H, Fukumaki Y. 2003. Positive association of the AMPA receptor subunit GluR4 (GRIA4) haplotype with schizophrenia: linkage disequilibrium mapping using SNPs evenly distributed across the gene region. Am J Med Genet 116B:17-22.
    • (2003) Am J Med Genet , vol.116 B , pp. 17-22
    • Makino, C.1    Fujii, Y.2    Kikuta, R.3    Hirata, N.4    Tani, A.5    Shibata, A.6    Ninomiya, H.7    Tashiro, N.8    Shibata, H.9    Fukumaki, Y.10
  • 51
    • 38149138747 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor 3 (GRM3) gene variation is not associated with schizophrenia or bipolar affective disorder in the German population
    • Martí SB, Cichon S, Propping P, Nothen M. 2002. Metabotropic glutamate receptor 3 (GRM3) gene variation is not associated with schizophrenia or bipolar affective disorder in the German population. Am J Med Genet 114:46-50.
    • (2002) Am J Med Genet , vol.114 , pp. 46-50
    • Martí, S.B.1    Cichon, S.2    Propping, P.3    Nothen, M.4
  • 53
    • 0029131849 scopus 로고
    • Genetic basis of schizophrenia
    • McGuffin P, Owen MJ, Farmer AE. 1995. Genetic basis of schizophrenia. Lancet 346:678-682.
    • (1995) Lancet , vol.346 , pp. 678-682
    • McGuffin, P.1    Owen, M.J.2    Farmer, A.E.3
  • 54
  • 55
    • 0032575715 scopus 로고    scopus 로고
    • Reversal of phencyclidine effects by a group II metabotropic glutamate receptor agonist in rats
    • Moghaddam B, Adams BW. 1998. Reversal of phencyclidine effects by a group II metabotropic glutamate receptor agonist in rats. Science 281:1349-1352.
    • (1998) Science , vol.281 , pp. 1349-1352
    • Moghaddam, B.1    Adams, B.W.2
  • 56
    • 0030900732 scopus 로고    scopus 로고
    • Activation of glutamatergic neurotransmission by ketamine: A novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with the prefrontal cortex
    • Moghaddam B, Adams B, Verma A, Daly D. 1997. Activation of glutamatergic neurotransmission by ketamine: a novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with the prefrontal cortex. J Neurosci 17:2921-2927.
    • (1997) J Neurosci , vol.17 , pp. 2921-2927
    • Moghaddam, B.1    Adams, B.2    Verma, A.3    Daly, D.4
  • 57
    • 0033588176 scopus 로고    scopus 로고
    • Mice with reduced NMDA receptor expression display behaviors related to schizophrenia
    • Mohn AR, Gainetdinov RR, Caron MG, Koller BH. 1999. Mice with reduced NMDA receptor expression display behaviors related to schizophrenia. Cell 98:427-436.
    • (1999) Cell , vol.98 , pp. 427-436
    • Mohn, A.R.1    Gainetdinov, R.R.2    Caron, M.G.3    Koller, B.H.4
  • 59
    • 0025804443 scopus 로고
    • Glutamate-operated channels: Developmentally early and mature forms arise by alternative splicing
    • Monyer H, Seeburg PH, Wisden W. 1991. Glutamate-operated channels: developmentally early and mature forms arise by alternative splicing. Neuron 6:799-810.
    • (1991) Neuron , vol.6 , pp. 799-810
    • Monyer, H.1    Seeburg, P.H.2    Wisden, W.3
  • 62
    • 0027938848 scopus 로고
    • Metabotropic glutamate receptors: Synaptic transmission, modulation, and plasticity
    • Nakanishi S. 1994. Metabotropic glutamate receptors: synaptic transmission, modulation, and plasticity. Neuron 13:1031-1037.
    • (1994) Neuron , vol.13 , pp. 1031-1037
    • Nakanishi, S.1
  • 63
    • 0033838797 scopus 로고    scopus 로고
    • Novel polymorphism in the gene region encoding the carboxyl-terminal intracellular domain of the NMDA receptor 2B subunit: Analysis of association with schizophrenia
    • Nishiguchi N, Shirakawa O, Ono H, Hashimoto T, Maeda K. 2000. Novel polymorphism in the gene region encoding the carboxyl-terminal intracellular domain of the NMDA receptor 2B subunit: analysis of association with schizophrenia. Am J Psychiat 157:1329-1331.
    • (2000) Am J Psychiat , vol.157 , pp. 1329-1331
    • Nishiguchi, N.1    Shirakawa, O.2    Ono, H.3    Hashimoto, T.4    Maeda, K.5
  • 64
    • 0032078391 scopus 로고    scopus 로고
    • Expression of the human excitatory amino acid transporter 2 and metabotropic glutmnate receptors 3 and 5 in the prefrontal cortex from normal individuals and patients with schizophrenia
    • Ohnuma T, Augood SJ, Arai H, McKenna PJ, Emson PC. 1998. Expression of the human excitatory amino acid transporter 2 and metabotropic glutmnate receptors 3 and 5 in the prefrontal cortex from normal individuals and patients with schizophrenia. Brain Res Mol Brain Res 56:207-217.
    • (1998) Brain Res Mol Brain Res , vol.56 , pp. 207-217
    • Ohnuma, T.1    Augood, S.J.2    Arai, H.3    McKenna, P.J.4    Emson, P.C.5
  • 66
    • 0034940397 scopus 로고    scopus 로고
    • Mutation screening of the metabotropic glutamate receptor mGluR4 (GRM4) gene in patients with schizophrenia
    • Ohtsuki T, Toru M, Arinami T. 2001b. Mutation screening of the metabotropic glutamate receptor mGluR4 (GRM4) gene in patients with schizophrenia. Psychiatr Genet 11:79-83.
    • (2001) Psychiatr Genet , vol.11 , pp. 79-83
    • Ohtsuki, T.1    Toru, M.2    Arinami, T.3
  • 68
    • 0028912822 scopus 로고
    • The metabotropic glutamate receptors: Structure and functions
    • Pin JP, Duvoisin R. 1995. The metabotropic glutamate receptors: structure and functions. Neuropharmacology 34:1-26.
    • (1995) Neuropharmacology , vol.34 , pp. 1-26
    • Pin, J.P.1    Duvoisin, R.2
  • 69
    • 0030933984 scopus 로고    scopus 로고
    • Distribution of kainate receptor subunit mRNAs in human hippocampus, neocortex and cerebellum, and bilateral reduction of hippocampal GluR6 and KA2 transcripts in schizophrenia
    • Porter RH, Eastwood SL, Harrison PJ. 1997. Distribution of kainate receptor subunit mRNAs in human hippocampus, neocortex and cerebellum, and bilateral reduction of hippocampal GluR6 and KA2 transcripts in schizophrenia. Brain Res 751:217-31.
    • (1997) Brain Res , vol.751 , pp. 217-231
    • Porter, R.H.1    Eastwood, S.L.2    Harrison, P.J.3
  • 72
    • 0035059959 scopus 로고    scopus 로고
    • Identification of single nucleotide polymorphisms (SNPs) and other sequence changes and estimation of nucleotide diversity in coding and flanking regions of the NMDAR1 receptor gene in schizophrenic patients
    • Rice SR, Niu N, Berman DB, Heston LL, Sobell JL. 2001. Identification of single nucleotide polymorphisms (SNPs) and other sequence changes and estimation of nucleotide diversity in coding and flanking regions of the NMDAR1 receptor gene in schizophrenic patients. Mol Psychiat 6:274-284.
    • (2001) Mol Psychiat , vol.6 , pp. 274-284
    • Rice, S.R.1    Niu, N.2    Berman, D.B.3    Heston, L.L.4    Sobell, J.L.5
  • 74
    • 0034018285 scopus 로고    scopus 로고
    • Linkage and associated studies of schizophrenia
    • Riley BP, McGuffin P. 2000. Linkage and associated studies of schizophrenia. Am J Med Genet 97:23-44.
    • (2000) Am J Med Genet , vol.97 , pp. 23-44
    • Riley, B.P.1    McGuffin, P.2
  • 75
    • 0034660559 scopus 로고    scopus 로고
    • Searching for genetic determinants in the new millennium
    • Risch NJ. 2000. Searching for genetic determinants in the new millennium. Nature 405:847-856.
    • (2000) Nature , vol.405 , pp. 847-856
    • Risch, N.J.1
  • 76
    • 0032486422 scopus 로고    scopus 로고
    • The tetrameric structure of a glutamate receptor channel
    • Rosenmund C, Stern-Bach Y, Stevens CF. 1998. The tetrameric structure of a glutamate receptor channel. Science 280:1596-1599.
    • (1998) Science , vol.280 , pp. 1596-1599
    • Rosenmund, C.1    Stern-Bach, Y.2    Stevens, C.F.3
  • 77
    • 0034704380 scopus 로고    scopus 로고
    • Mutation analysis of the N-methyl-D-aspartate receptor NR1 subunit gene (GRIN1) in schizophrenia
    • Sakurai K, Toru M, Yamakawa-Kobayashi K, Arinami T. 2000. Mutation analysis of the N-methyl-D-aspartate receptor NR1 subunit gene (GRIN1) in schizophrenia. Neurosci Lett. 296:168-170.
    • (2000) Neurosci Lett , vol.296 , pp. 168-170
    • Sakurai, K.1    Toru, M.2    Yamakawa-Kobayashi, K.3    Arinami, T.4
  • 81
    • 0037174634 scopus 로고    scopus 로고
    • Postsynaptic signaling and plasticity mechanisms
    • Sheng M, Kim MJ. 2002. Postsynaptic signaling and plasticity mechanisms. Science 298:776-780.
    • (2002) Science , vol.298 , pp. 776-780
    • Sheng, M.1    Kim, M.J.2
  • 83
    • 0037114827 scopus 로고    scopus 로고
    • Association study of polymorphisms in the GluR6 kainate receptor gene (GRIK2) with schizophrenia
    • Shibata H, Shibata A., Ninomiya H., Tashiro N, Fukumaki Y. 2002. Association study of polymorphisms in the GluR6 kainate receptor gene (GRIK2) with schizophrenia. Psychiatr Res 113:59-67.
    • (2002) Psychiatr Res , vol.113 , pp. 59-67
    • Shibata, H.1    Shibata, A.2    Ninomiya, H.3    Tashiro, N.4    Fukumaki, Y.5
  • 84
    • 0019317286 scopus 로고
    • Phencyclidine
    • Snyder SH. 1980. Phencyclidine. Nature 285:355-356.
    • (1980) Nature , vol.285 , pp. 355-356
    • Snyder, S.H.1
  • 85
    • 0031774346 scopus 로고    scopus 로고
    • Expression of NMDAR1, GluR1, GluR7, and KA1 glutamate receptor mRNAs is decreased in frontal cortex of "neuroleptic-free" schizophrenics: Evidence on reversible upregulation by typical neuroleptics
    • Sokolov BP. 1998. Expression of NMDAR1, GluR1, GluR7, and KA1 glutamate receptor mRNAs is decreased in frontal cortex of "neuroleptic-free" schizophrenics: evidence on reversible upregulation by typical neuroleptics. J Neurochem 71:2454-2464.
    • (1998) J Neurochem , vol.71 , pp. 2454-2464
    • Sokolov, B.P.1
  • 86
    • 0025995296 scopus 로고
    • RNA editing in brain controls a determinant of ion flow in glutamate-gated channels
    • Sommer B, Kohler M, Sprengel R, Seeburg PH. 1991. RNA editing in brain controls a determinant of ion flow in glutamate-gated channels. Cell 67:11-19.
    • (1991) Cell , vol.67 , pp. 11-19
    • Sommer, B.1    Kohler, M.2    Sprengel, R.3    Seeburg, P.H.4
  • 87
    • 0036829584 scopus 로고    scopus 로고
    • Regulation of AMPA receptors during synaptic plasticity
    • Song I, Huganir RL. 2002. Regulation of AMPA receptors during synaptic plasticity. Trends Neurosci 25:578-588.
    • (2002) Trends Neurosci , vol.25 , pp. 578-588
    • Song, I.1    Huganir, R.L.2
  • 90
    • 0036842371 scopus 로고    scopus 로고
    • Polymorphism analysis of the upstream region of the human N-methyl-D-aspartate receptor subunit NR1 gene (GRIN1): Implications for schizophrenia
    • Tani A, Kikuta R, Itoh K, Joo A, Shibata H, Ninomiya H, Tashiro N, Fukumaki Y. 2002. Polymorphism analysis of the upstream region of the human N-methyl-D-aspartate receptor subunit NR1 gene (GRIN1): implications for schizophrenia. Schizophr Res 58:83-86.
    • (2002) Schizophr Res , vol.58 , pp. 83-86
    • Tani, A.1    Kikuta, R.2    Itoh, K.3    Joo, A.4    Shibata, H.5    Ninomiya, H.6    Tashiro, N.7    Fukumaki, Y.8
  • 91
    • 0028137844 scopus 로고
    • Biochemical and assembly properties of GluR6 and KA2, two members of the kainate receptor family, determined with subunit-specific antibodies
    • Wenthold RJ, Trumpy VA, Zhu WS, Petralia RS. 1994. Biochemical and assembly properties of GluR6 and KA2, two members of the kainate receptor family, determined with subunit-specific antibodies. J Biol Chem 269:1332-1339.
    • (1994) J Biol Chem , vol.269 , pp. 1332-1339
    • Wenthold, R.J.1    Trumpy, V.A.2    Zhu, W.S.3    Petralia, R.S.4
  • 92
    • 0035985470 scopus 로고    scopus 로고
    • Determination of the genomic structure and mutation screening in schizophrenic individuals for five subunits of the N-methyl-D-aspartate glutamate receptor
    • Williams NM, Bowen T, Spurlock G, Norton N, Williams HJ, Hoogendoorn B, Owen MJ, O'Donovan MC. 2002. Determination of the genomic structure and mutation screening in schizophrenic individuals for five subunits of the N-methyl-D-aspartate glutamate receptor. Mol Psychiat 7:508-514.
    • (2002) Mol Psychiat , vol.7 , pp. 508-514
    • Williams, N.M.1    Bowen, T.2    Spurlock, G.3    Norton, N.4    Williams, H.J.5    Hoogendoorn, B.6    Owen, M.J.7    O'Donovan, M.C.8
  • 93
    • 0001200144 scopus 로고
    • Testing linkage disequilibrium between a disease gene and marker loci
    • Xie X, Ott J. 1993. Testing linkage disequilibrium between a disease gene and marker loci. Am J Hum Genet 53:1107.
    • (1993) Am J Hum Genet , vol.53 , pp. 1107
    • Xie, X.1    Ott, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.