Metabotropic glutamate receptor mRNA expression in the schizophrenic thalamus

Biological Psychiatry

Volumn 47, Issue 1, 2000, Pages 22-28

  Richardson Burns, Sarah M ^a   Haroutunian, Vahram ^b   Davis, Kenneth L ^b   Watson, Stanley J ^a   Meador Woodruff, James H ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b MOUNT SINAI MEDICAL CENTER   (United States)

Author keywords

Dorsomedial thalamic nucleus; Glutamate receptors; In situ hybridization; mGluR; Oligonucleotide; Schizophrenia

Indexed keywords

GLUTAMATE RECEPTOR; IONOTROPIC RECEPTOR; MESSENGER RNA; METABOTROPIC RECEPTOR; RECEPTOR SUBTYPE;

ADULT; AGED; ARTICLE; AUTOPSY; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN TISSUE; INFORMATION PROCESSING; MALE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; SCHIZOPHRENIA; THALAMUS;

AGED; AGED, 80 AND OVER; CASE-CONTROL STUDIES; CHRONIC DISEASE; FEMALE; GENE EXPRESSION; HUMANS; IN SITU HYBRIDIZATION; MALE; MIDDLE AGED; OLIGONUCLEOTIDES; RECEPTORS, METABOTROPIC GLUTAMATE; RECEPTORS, N-METHYL-D-ASPARTATE; RNA, MESSENGER; SCHIZOPHRENIA; THALAMIC NUCLEI;

EID: 0034653205     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3223(99)00207-3     Document Type: Article

References (62)

1. Akbarian S., Sucher N.J., Bradley D., Tafazzoli A., Trinh D., Hetrick W.P., Potkin S.G., Sandman C.A., Bunney W.E. Jr, Jones E.G. Selective alterations in gene expression for NMDA receptor subunits in prefrontal cortex of schizophrenics. Journal of Neuroscience. 16:1996;19-30.
2. Altschul S., Stehen F., Gish W., Miller W., Myers E., Lipman D. Basic local alignment search tool. Journal of Molecular Biology. 215:1990;403-410.
3. Andreasen N.C. The role of the thalamus in schizophrenia. Canadian Journal of Psychiatry. 42:1997;27-33.
4. Andreasen N.C., Arndt S., Swayze V., Cizadlo T., Flaum M., O'Leary D., Ehrhardt J.C., Yuh W.T. Thalamic abnormalities in schizophrenia visualized through magnetic resonance image averaging. Science. 266:1994;294-298.
5. Andreasen N.C., Paradiso S., O'Leary D.S. "Cognitive dysmetria" as an integrative theory of schizophrenia A dysfunction in cortical-subcortical-cerebellar circuitry? Schizophrenia Bulletin. 24:1998;203-218.
6. Andreasen N.C., Rezai K., Alliger R., Swayze V., Flaum M., Kirchner P., Cohen G., O'Leary D. Hypofrontality in neuroleptic-naive patients and in patients with chronic schizophrenia. Archives of General Psychiatry. 49:1992;439-958.
7. Aniksztejn L., Otani S., Ben-Ari Y. Quisqualate metabotropic receptors modulate NMDA currents and facilitate induction of long-term potentiation through protein kinase C. Eur J Neurosci. 4:1992;500-505.
8. Anwyl R. Metabotropic glutamate receptors Electrophysiological properties and role in plasticity . Brain Res Rev. 29:1999;83-120.
9. Attarian S., Amalric M. Microinfusion of the metabotropic glutamate receptor agonist 1S,3R-1-aminocyclopentane-1,3-dicarboxylic acid into the nucleus accumbens induces dopamine-dependent locomotor activation in the rat. Eur J Neurosci. 9:1997;809-816.
10. Bleakman D., Rusin K.I., Chard P.S., Glaum S.R., Miller R.J. Metabotropic glutamate receptors potentiate ionotropic glutamate responses in the rat dorsal horn. Mol Pharmacol. 42:1992;192-196.
11. Bortolotto Z.A., Bashir Z.I., Davies C.H., Collingridge G.L. A molecular switch activated by metabotropic glutamate receptors regulates induction of long-term potentiation. Nature. 368:1994;740-743.
12. Buchsbaum M.S., Someya T., Teng C.Y., Abel L., Chin S., Najafi A., et al. PET and MRI of the thalamus in never-mediated patients with schizophrenia. Am J Psychiatry. 153:1996;191-199.
13. Calabresi P., Maj R., Pisani A., Mercuri N.B., Bernardi G. Long-term synaptic depression in the striatum Physiological and pharmacological characterization . J Neurosci. 12:1992;4224-4233.
14. Calabresi P., Mercuri N.B., Bernardi G. Activation of quisqualate metabotropic receptors reduces glutamate and GABA-mediated synpatic potentials in the rat striatum. Neurosci Lett. 139:1992;41-44.
15. Carlsson A., Hansson L.O., Waters N., Carlsson M.L. Neurotransmitter aberrations in schizophrenia New perspectives and therapeutic implications . Life Sci. 61:1997;75-94.
16. Carpenter W.T., Buchanan R.W., Kirkpatrick B., Tamminga C.A., Wood F. Strong inference, theory testing and the neuroanatomy of schizophrenia. Arch Gen Psychiatry. 50:1993;825-831.
17. Colwell C.S., Levine M.S. Metabotropic glutamate receptors modulate N-methyl-D-aspartate receptor function in neostriatal neurons. Neuroscience. 61:1994;497-507.
18. Corti C., Restituito S., Rimland J.M., Brabet I., Corsi M., Pin J.P., et al. Cloning and characterization of alternative mRNA forms for the rat metabotropic glutamate receptors mGluR7 and mGluR8. Eur J Neurosci. 10:1998;3629-3641.
19. Danos P., Baumann B., Bernstein H.-G., Franz M., Stauch R., Northoff G., et al. Schizophrenia and anteroventral thalamic nucleus Selective decrease of parvalbumin-immunoreactive thalamocortical projection neurons . Psychiatry Res Neuroimaging. 82:1998;1-10.
20. Duvoisin R.M., Zhang C., Ramonell K. A novel metabotropic glutamate receptor expressed in the retina and olfactory bulb. J Neurosci. 15:1995;3075-3083.
21. Feenstra M.G.P., Botterblom M.H.A., van Uum J.F.M. Local activation of metabotropic glutamate receptors inhibits the handling-induced increased release of dopamine in the nucleus accumbens but not that of dopamine or noradrenaline in the prefrontal cortex Comparison with inhibition of ionotropic receptors . J Neurochem. 70:1998;1106-1113.
22. Glaum S.R., Miller R.J. Metabotropic glutamate receptors mediate excitatory transmission in the nucleus of the solitary tract. J Neurosci. 12:1992;2251-2258.
23. Greenamyre J.T., Porter R.H.P. Anatomy and physiology of glutamate in the CNS. Neurology. 44:(suppl 8):1994;s7-s13.
24. Halberstadt A.L. The phencyclidine-glutamate model of schizophrenia. Clin Neuropharmacol. 18:1995;237-249.
25. Healy D.J., Haroutunian V., Powchik P., Davidson M., Davis K.L., Watson S.J., et al. AMPA receptor binding and subunit mRNA expression in prefrontal cortex and striatum of elderly schizophrenics. Neuropsychopharmacology. 19:1998;278-286.
26. Heckers S. Neuropathology of schizophrenia Cortex, thalamus, basal ganglia, and neurotransmitter-specific projection systems . Schizophr Bull. 23:1997;403-421.
27. Holscher C., Gigg J., O'Mara S. Metabotropic glutamate receptor activation and blockade Their role in long-term potentiation, learning, and neurotoxicity . Neurosci Biobehav Rev. 23:1999;399-410.
28. Ibrahim H., Haroutunian V., Davis K.L., Watson S.J., Meador-Woodruff J.H. Thalamic glutamate receptor expression in schizophrenia. Biol Psychiatry. 45:(suppl):1999;27S.
29. Jones E.G. Cortical development and thalamic pathology in schizophrenia. Schizophr Bull. 23:1997;483-501.
30. Kaatz K.W., Albin R.L. Intrastriatal and intrasubthalamic stimulation of metabotropic glutamate receptors A behavioral and FOS immunohistochemical study . Neuroscience. 66:1995;55-65.
31. Kim J.H., Vezina P. Metabotropic glutamate receptors are necessarry for sensitization by amphetamine. Neuroreport. 9:1998;403-406.
32. Liu X.B., Munoz A., Jones E.G. Changes in subcellular localization of metabotropic glutamate receptor subtypes during postnatal development of mouse thalamus. J Comp Neurol. 395:1998;450-465.
33. Mai J.K., Assheuer J., Paxinos G. Atlas of the Human Brain. 1997;Academic Press, San Diego.
34. Manaye K.F., Liang C.-L., Hicks P.B., German D.C., Young K.A. Nerve cell numbers in thalamic anterior and mediodorsal nuclei are selectively reduced in schizophrenia. Soc Neurosci Abstr. 24:1998;1236.
35. McCormick D.A., Von Krosigk M. Corticothalamic activation modulates thalamic firing through glutamate `metabotropic' receptors. Proc Nat Acad Sci U S A. 89:1992;2774-2778.
36. Meador-Woodruff J.H., Haroutunian V., Powchik P., Davidson M., Davis K.L., Watson S.J. Dopamine receptor transcript expression in striatum, perfrontal and occipital cortex Focal abnormalities in orbitofrontal cortex in schizophrenia . Arch Gen Psychiatry. 54:1997;1089-1095.
37. Moghaddam B., Adams B.W. Reversal of phencyclidine effects by a group II metabotropic glutamate receptor agonist in rats. Science. 281:1998;1349-1352.
38. Nakajima Y., Iwakabe H., Akazawa C., Nawa H., Shigemoto R., Mizuno N., et al. Molecular characterization of a novel retinal metabotropic glutamate receptor mGluR6 with a high agonist selectivity for 1-2-amino-4-phosphonobutyrate. J Biol Chem. 268:1993;11868-11873.
39. Nakanishi S. Molecular diversity of glutamate receptors and implications for brain function. Science. 258:1992;597-603.
40. Nakanishi S. Metabotropic glutamate receptors Synaptic transmission, modulation, and plasticity . Neuron. 13:1994;1031-1037.
41. Olney J.W., Farber N.B. Glutamate receptor dysfunction and schizophrenia. Arch Gen Psychiatry. 52:1995;998-1007.
42. Pakkenberg B. Pronounced reduction of total neuron number in mediodorsal thalamic nucleus and nucleus accumbens in schizophrenics. Arch Gen Psychiatry. 47:1990;1023-1028.
43. Pakkenberg B. The volume of the mediodorsal thalamic nucleus in treated and unteated schizophrenics. Schizophr Res. 7:1992;95-100.
44. Pakkenberg B. Total nerve cell number in neocortex in chronic schizophrenics and controls estimated using optical disectors. Biol Psychiatry. 34:1993;768-772.
45. Pakkenberg B. Leucotomized schizophrenics lose neurons in the mediodorsal thalamic nucleus. Neuropathol Appl Neurobiol. 19:1993;373-380.
46. Pin J.P., Duvoisin R. The metabotropic glutamate receptors Structue and functions . Neuropharmacology. 34:1995;1-26.
47. Pizzi M., Consolandi O., Memo M., Spano P.F. Activation of multiple metabotropic glutamate receptor subtypes prevents NMDA-induced excitotoxicity in rat hippocampal slices. Eur J Neurosci. 8:1996;1516-1521.
48. Popken G.J., Bunney W.E., Potkin S.G., Jones E.G. Neuron number and GABA-ergic and glutamatergic mRNA expression in subdivisions of the thalamic mediodorsal nucleus of schizophrenics. Soc Neurosci Abst. 24:1998;991.
49. Portas C.M., Goldstein J.M., Shenton M.E., Hokama H.H., Wible C.G., Fischer I., et al. Volumetric evaluation of the thalamus in schizophrenic male patients using magnetic resonance imaging. Biol Psychiatry. 43:1998;649-659.
50. Prezeau L., Carrette J., Helpap B., Curry K., Pin J.P., Bockaert J. PHarmacological characterization of metabotropic glutamate receptors in several types of brain cells in primary cultures. Mol Pharmacol. 45:1994;570-577.
51. Richardson-Burns S.M., Haroutunian V., Davis K.L., Watson S.J., Meador-Woodruff J.H. Serotonin receptor mRNA abnormalities in schizophrenia thalamus. Biol Psychiatry. 45:(suppl):1999;28S.
52. Salt T.E., Eaton S.A. The function of metabotropic excitatory amino acid receptors in synaptic transmission in the thalamus Studies with novel phenyglycine anatgonists . Neurochem Int. 24:1994;451-458.
53. Salt T.E., Eaton S.A. Functions of ionotropic and metabotropic glutamate receptors in sensory transmission in the mammalian thalamus. Prog Neurobiol. 48:1996;55-72.
54. Sambrook J., Fritsch E.F., Maniatis T. Molecular Cloning A Laboratory Manual . 2nd ed. 1989;Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
55. Saugstad J.A., Kinzie J.M., Shinohara M.M., Segerson T.P., Westbook G.L. Cloning and expression of rat metabotropic glutamate receptor 8 reveals a distinct pharmacological profile. Mol Pharmacol. 51:1997;119-125.
56. Scherer S.W., Soder S., Duvoisin R.M., Huizenga J.J., Tsui L.-C. The human metabotropic glutamate receptor 8 (GRM8) gene A disproportionately large gene located at 7q31.3-q32.1 . Genomics. 44:1997;232-236.
57. Sherman A.D., Davidson A.T., Baruah S., Hegwood T.S., Waziri R. Evidence of glutamatergic deficiency in schizophrenia. Neurosci Lett. 121:1991;77-80.
58. Steinpreis R.E. The behavioral and neurochemical effects of phencyclidine in humans and animals Some implications for modeling psychosis . Behav Brain Res. 74:1996;45-55.
59. Steriade M., Jones E.G., Llinas R.R. Thalamus. 1997;Elsevier, Oxford.
60. Swartz K.J., Merritt A., Bean B.P., Lovinger D.M. Protein kinase C modulates glutamate receptor inhibition of calcium channels and synaptic transmission. Nature. 361:1993;165-168.
61. Tamminga C.A. Schizophrenia and glutamatergic transmission. Crit Rev Neurobiol. 12:1997;21-36.
62. Wisden W., Morris B.J. In Situ Hybridization Protocols for the Brain. 1994;Academic Press, Cambridge, UK.