-
2
-
-
0343409409
-
Insulin-degrading enzyme
-
P. Cuatrecasas, & S. Jacobs. Berlin/Heidelberg: Springer-Verlag
-
Duckworth W. C. Insulin-degrading enzyme. Cuatrecasas P., Jacobs S. Handbook of Experimental Pharmacology. 1990;143-165 Springer-Verlag, Berlin/Heidelberg.
-
(1990)
Handbook of Experimental Pharmacology
, pp. 143-165
-
-
Duckworth, W.C.1
-
3
-
-
0024215473
-
Human insulin-degrading enzyme shares structural and functional homologies with E. coli protease III
-
Affholter J. A., Fried V. A., Roth R. A. Human insulin-degrading enzyme shares structural and functional homologies with E. coli protease III. Science. 242:1988;1415-1418.
-
(1988)
Science
, vol.242
, pp. 1415-1418
-
-
Affholter, J.A.1
Fried, V.A.2
Roth, R.A.3
-
4
-
-
0025119656
-
Insulin-degrading enzyme: Stable expression of the human complementary DNA, characterization of its protein product, and chromosomal mapping of the human and mouse genes
-
Affholter J. A., Hsieh C.-L., Francke U., Roth R. A. Insulin-degrading enzyme: Stable expression of the human complementary DNA, characterization of its protein product, and chromosomal mapping of the human and mouse genes. Mol. Endocrinol. 4:1990;1125-1135.
-
(1990)
Mol. Endocrinol.
, vol.4
, pp. 1125-1135
-
-
Affholter, J.A.1
Hsieh, C.-L.2
Francke, U.3
Roth, R.A.4
-
5
-
-
0025080986
-
Cloning and expression of the cDNA for a Drosophila insulin-degrading enzyme
-
Kuo W.-L., Gehm B. D., Rosner M. R. Cloning and expression of the cDNA for a Drosophila insulin-degrading enzyme. Mol. Endocrinol. 4:1990;1580-1591.
-
(1990)
Mol. Endocrinol.
, vol.4
, pp. 1580-1591
-
-
Kuo, W.-L.1
Gehm, B.D.2
Rosner, M.R.3
-
6
-
-
0027410472
-
The rat insulin-degrading enzyme: Molecular cloning and characterization of tissue-specific transcripts
-
Baumeister H., Müller D., Rehbein M., Richter D. The rat insulin-degrading enzyme: Molecular cloning and characterization of tissue-specific transcripts. FEBS Lett. 317:1993;250-254.
-
(1993)
FEBS Lett.
, vol.317
, pp. 250-254
-
-
Baumeister, H.1
Müller, D.2
Rehbein, M.3
Richter, D.4
-
7
-
-
0027941838
-
Families of zinc metalloproteases
-
Hooper N. M. Families of zinc metalloproteases. FEBS Lett. 354:1994;1-6.
-
(1994)
FEBS Lett.
, vol.354
, pp. 1-6
-
-
Hooper, N.M.1
-
8
-
-
0024076281
-
Identification of peroxisomal targeting signals located at the carboxy terminus of four peroxisomal proteins
-
Gould S. J., Keller G.-A., Subramani S. Identification of peroxisomal targeting signals located at the carboxy terminus of four peroxisomal proteins. J. Cell Biol. 107:1988;897-905.
-
(1988)
J. Cell Biol.
, vol.107
, pp. 897-905
-
-
Gould, S.J.1
Keller, G.-A.2
Subramani, S.3
-
9
-
-
0031941276
-
Components involved in peroxisome import, biogenesis, proliferation, turnover, and movement
-
Subramani S. Components involved in peroxisome import, biogenesis, proliferation, turnover, and movement. Physiol. Rev. 78:1998;171-188.
-
(1998)
Physiol. Rev.
, vol.78
, pp. 171-188
-
-
Subramani, S.1
-
10
-
-
0027964969
-
Inducible expression and cellular localization of insulin-degrading enzyme in a stably transfected cell line
-
Kuo W.-L., Gehm B. D., Rosner M. R., Li W., Keller G. Inducible expression and cellular localization of insulin-degrading enzyme in a stably transfected cell line. J. Biol. Chem. 269:1994;22599-22606.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 22599-22606
-
-
Kuo, W.-L.1
Gehm, B.D.2
Rosner, M.R.3
Li, W.4
Keller, G.5
-
11
-
-
0030787591
-
Insulin-degrading enzyme does not require peroxisomal localization for insulin degradation
-
Chesneau V., Perlman R. K., Li W., Keller G.-A., Rosner M. R. Insulin-degrading enzyme does not require peroxisomal localization for insulin degradation. Endocrinology. 138:1997;3444-3451.
-
(1997)
Endocrinology
, vol.138
, pp. 3444-3451
-
-
Chesneau, V.1
Perlman, R.K.2
Li, W.3
Keller, G.-A.4
Rosner, M.R.5
-
12
-
-
0023924128
-
Isolation of insulin degradation products from endosomes derived from intact rat liver
-
Hamel F. G., Posner B. I., Bergeron J. J. M., Frank B. H., Duckworth W. C. Isolation of insulin degradation products from endosomes derived from intact rat liver. J. Biol. Chem. 263:1988;6703-6708.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 6703-6708
-
-
Hamel, F.G.1
Posner, B.I.2
Bergeron, J.J.M.3
Frank, B.H.4
Duckworth, W.C.5
-
13
-
-
0023906369
-
Degradation products of insulin generated by hepatocytes and by insulin protease
-
Duckworth W. C., Hamel F. G., Peavy D. E., Liepnieks J. J., Ryan M. P., Hermodson M. A., Frank B. H. Degradation products of insulin generated by hepatocytes and by insulin protease. J. Biol. Chem. 263:1988;1826-1833.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 1826-1833
-
-
Duckworth, W.C.1
Hamel, F.G.2
Peavy, D.E.3
Liepnieks, J.J.4
Ryan, M.P.5
Hermodson, M.A.6
Frank, B.H.7
-
14
-
-
0022445076
-
Inhibition of insulin degradation by hepatoma cells after microinjection of monoclonal antibodies to a specific cytosolic protease
-
Shii K., Roth R. A. Inhibition of insulin degradation by hepatoma cells after microinjection of monoclonal antibodies to a specific cytosolic protease. Proc. Natl. Acad. Sci. USA. 83:1986;4147-4151.
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 4147-4151
-
-
Shii, K.1
Roth, R.A.2
-
15
-
-
0024335103
-
6 myoblasts inhibit insulin degradation by the endogenous insulin-degrading enzyme
-
6 myoblasts inhibit insulin degradation by the endogenous insulin-degrading enzyme. J. Biol. Chem. 264:1989;8928-8934.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 8928-8934
-
-
Kayalar, C.1
Wong, W.T.2
-
16
-
-
0025809406
-
Regulation of insulin, epidermal growth factor, and transforming growth factor-α levels by growth factor-degrading enzymes
-
Gehm B. D., Rosner M. R. Regulation of insulin, epidermal growth factor, and transforming growth factor-α levels by growth factor-degrading enzymes. Endocrinology. 128:1991;1603-1610.
-
(1991)
Endocrinology
, vol.128
, pp. 1603-1610
-
-
Gehm, B.D.1
Rosner, M.R.2
-
17
-
-
0023164755
-
125I]-insulin with a cytosolic insulin-degrading enzyme: Detection by covalent cross-linking and immunoprecipitation with a monoclonal antibody
-
125I]-insulin with a cytosolic insulin-degrading enzyme: Detection by covalent cross-linking and immunoprecipitation with a monoclonal antibody. Endocrinology. 120:1987;829-831.
-
(1987)
Endocrinology
, vol.120
, pp. 829-831
-
-
Hari, J.1
Shii, K.2
Roth, R.A.3
-
18
-
-
0026049145
-
Regulation of insulin degradation: Expression of an evolutionary conserved insulin-degrading enzyme increases degradation via an intracellular pathway
-
Kuo W.-L., Gehm B. D., Rosner M. R. Regulation of insulin degradation: Expression of an evolutionary conserved insulin-degrading enzyme increases degradation via an intracellular pathway. Mol. Endocrinol. 5:1991;1467-1476.
-
(1991)
Mol. Endocrinol.
, vol.5
, pp. 1467-1476
-
-
Kuo, W.-L.1
Gehm, B.D.2
Rosner, M.R.3
-
19
-
-
0021195660
-
Degradation of insulin-like growth factors I and II by a human insulin degrading enzyme
-
Roth R. A., Mesirow M. L., Yokono K., Baba S. Degradation of insulin-like growth factors I and II by a human insulin degrading enzyme. Endocrine Res. 10:1984;101-112.
-
(1984)
Endocrine Res.
, vol.10
, pp. 101-112
-
-
Roth, R.A.1
Mesirow, M.L.2
Yokono, K.3
Baba, S.4
-
20
-
-
0025987157
-
Atrial natriuretic peptide (ANP) is a high-affinity substrate for rat insulin-degrading enzyme
-
Müller D., Baumeister H., Buck F., Richter D. Atrial natriuretic peptide (ANP) is a high-affinity substrate for rat insulin-degrading enzyme. Eur. J. Biochem. 202:1991;285-292.
-
(1991)
Eur. J. Biochem.
, vol.202
, pp. 285-292
-
-
Müller, D.1
Baumeister, H.2
Buck, F.3
Richter, D.4
-
21
-
-
0026471959
-
Rat insulin-degrading enzyme: Cleavage pattern of the natriuretic peptide hormones ANP, BNP, and CNP revealed by HPLC and mass spectrometry
-
Müller D., Schulze C., Baumeister H., Buck F., Richter D. Rat insulin-degrading enzyme: cleavage pattern of the natriuretic peptide hormones ANP, BNP, and CNP revealed by HPLC and mass spectrometry. Biochemistry. 31:1992;11138-11143.
-
(1992)
Biochemistry
, vol.31
, pp. 11138-11143
-
-
Müller, D.1
Schulze, C.2
Baumeister, H.3
Buck, F.4
Richter, D.5
-
22
-
-
0024454036
-
An evolutionary conserved enzyme degrades transforming growth factor-alpha as well as insulin
-
Garcia J. V., Gehm B. D., Rosner M. R. An evolutionary conserved enzyme degrades transforming growth factor-alpha as well as insulin. J. Cell Biol. 109:1989;1301-1307.
-
(1989)
J. Cell Biol.
, vol.109
, pp. 1301-1307
-
-
Garcia, J.V.1
Gehm, B.D.2
Rosner, M.R.3
-
23
-
-
0029843563
-
Identification of γ-endorphin-generating enzyme as insulin-degrading enzyme
-
Safavi A., Miller B. C., Cottam L., Hersh L. B. Identification of γ-endorphin-generating enzyme as insulin-degrading enzyme. Biochemistry. 35:1996;14318-14325.
-
(1996)
Biochemistry
, vol.35
, pp. 14318-14325
-
-
Safavi, A.1
Miller, B.C.2
Cottam, L.3
Hersh, L.B.4
-
24
-
-
0028176821
-
Alzheimer's β-amyloid peptide specifically interacts with and is degraded by insulin degrading enzyme
-
Kurochkin I. V., Goto S. Alzheimer's β-amyloid peptide specifically interacts with and is degraded by insulin degrading enzyme. FEBS Lett. 345:1994;33-37.
-
(1994)
FEBS Lett.
, vol.345
, pp. 33-37
-
-
Kurochkin, I.V.1
Goto, S.2
-
25
-
-
1842367306
-
Degradation of amyloid β-protein by a metalloprotease secreted by microglia and other neural and non-neural cells
-
Qiu W. Q., Ye Z., Kholodenko D., Seubert P., Selkoe D. J. Degradation of amyloid β-protein by a metalloprotease secreted by microglia and other neural and non-neural cells. J. Biol. Chem. 272:1997;6641-6646.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 6641-6646
-
-
Qiu, W.Q.1
Ye, Z.2
Kholodenko, D.3
Seubert, P.4
Selkoe, D.J.5
-
26
-
-
0000398342
-
Insulin-degrading enzyme regulates extracellular levels of amyloid β-protein by degradation
-
Qiu W. Q., Walsh D. M., Ye Z., Vekrellis K., Zhang J., Podlisny M. B., Rosner M. R., Safavi A., Hersh L. B., Selkoe D. J. Insulin-degrading enzyme regulates extracellular levels of amyloid β-protein by degradation. J. Biol. Chem. 273:1998;32730-32738.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 32730-32738
-
-
Qiu, W.Q.1
Walsh, D.M.2
Ye, Z.3
Vekrellis, K.4
Zhang, J.5
Podlisny, M.B.6
Rosner, M.R.7
Safavi, A.8
Hersh, L.B.9
Selkoe, D.J.10
-
27
-
-
0032960305
-
Regulation of amyloid precursor protein cleavage
-
Mills J., Reiner P. B. Regulation of amyloid precursor protein cleavage. J. Neurochem. 72:1999;443-460.
-
(1999)
J. Neurochem.
, vol.72
, pp. 443-460
-
-
Mills, J.1
Reiner, P.B.2
-
28
-
-
0033600274
-
Translating cell biology into therapeutic advances in Alzheimer's disease
-
Selkoe D. J. Translating cell biology into therapeutic advances in Alzheimer's disease. Nature. 399:1999;A23-A31.
-
(1999)
Nature
, vol.399
-
-
Selkoe, D.J.1
-
29
-
-
0022473263
-
Purification and characterization of the insulin-degrading enzyme from human erythrocytes
-
Shii K., Yokono K., Baba S., Roth R. A. Purification and characterization of the insulin-degrading enzyme from human erythrocytes. Diabetes. 35:1986;675-683.
-
(1986)
Diabetes
, vol.35
, pp. 675-683
-
-
Shii, K.1
Yokono, K.2
Baba, S.3
Roth, R.A.4
-
30
-
-
0026527618
-
Affinity purification of insulin-degrading enzyme and its endogenous inhibitor from rat liver
-
Ogawa W., Shii K., Yonazawa K., Baba S., Yokono K. Affinity purification of insulin-degrading enzyme and its endogenous inhibitor from rat liver. J. Biol. Chem. 267:1992;1310-1316.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 1310-1316
-
-
Ogawa, W.1
Shii, K.2
Yonazawa, K.3
Baba, S.4
Yokono, K.5
-
32
-
-
0027454093
-
Functional analysis of conserved residues in the active site of insulin-degrading enzyme
-
Perlman R. K., Gehm B. D., Kuo W.-L., Rosner M. R. Functional analysis of conserved residues in the active site of insulin-degrading enzyme. J. Biol. Chem. 268:1993;21538-21544.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 21538-21544
-
-
Perlman, R.K.1
Gehm, B.D.2
Kuo, W.-L.3
Rosner, M.R.4
-
33
-
-
0027452730
-
Insulin-degrading enzyme is differentially expressed and developmentally regulated in various rat tissues
-
Kuo W.-L., Montag A. G., Rosner M. R. Insulin-degrading enzyme is differentially expressed and developmentally regulated in various rat tissues. Endocrinology. 132:1993;604-611.
-
(1993)
Endocrinology
, vol.132
, pp. 604-611
-
-
Kuo, W.-L.1
Montag, A.G.2
Rosner, M.R.3
-
34
-
-
0028587344
-
Identification of zinc ligands of the insulin-degrading enzyme
-
Perlman R. K., Rosner M. R. Identification of zinc ligands of the insulin-degrading enzyme. J. Biol. Chem. 269:1994;33140-33145.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 33140-33145
-
-
Perlman, R.K.1
Rosner, M.R.2
-
35
-
-
0024286090
-
Isolation and characterization of an insulin-degrading enzyme from Drosophila melanogaster
-
Garcia J. V., Fenton B. W., Rosner M. R. Isolation and characterization of an insulin-degrading enzyme from Drosophila melanogaster. Biochemistry. 27:1988;4237-4244.
-
(1988)
Biochemistry
, vol.27
, pp. 4237-4244
-
-
Garcia, J.V.1
Fenton, B.W.2
Rosner, M.R.3
-
36
-
-
0023665902
-
An analysis of 5′-noncoding sequences from 699 vertebrate messenger RNAs
-
Kozak M. An analysis of 5′-noncoding sequences from 699 vertebrate messenger RNAs. Nucleic Acids Res. 15:1987;8125-8148.
-
(1987)
Nucleic Acids Res.
, vol.15
, pp. 8125-8148
-
-
Kozak, M.1
-
37
-
-
0031550507
-
Overexpression of insulin degrading enzyme: Cellular localization and effects of insulin signaling
-
Seta K. A., Roth R. A. Overexpression of insulin degrading enzyme: cellular localization and effects of insulin signaling. Biochem. Biophys. Res. Commun. 231:1997;167-171.
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.231
, pp. 167-171
-
-
Seta, K.A.1
Roth, R.A.2
|