Differential degradation of amyloid β genetic variants associated with hereditary dementia or stroke by insulin-degrading enzyme

Journal of Biological Chemistry

Volumn 278, Issue 26, 2003, Pages 23221-23226

  Morelli, Laura ^a   Llovera, Ramiro ^a   Gonzalez, Silvia A ^b   Affranchino, José L ^b   Prelli, Frances ^c   Frangione, Blas ^c   Ghiso, Jorge ^c   Castaño, Eduardo M ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b Facultad de Ciencias Naturales e Instituto M Lillo   (Argentina)

^c NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME KINETICS; HYDROLYSIS; POLYPEPTIDES; SUBSTITUTION REACTIONS;

PROTEOLYSIS;

AMINO ACIDS;

AMYLOID BETA PROTEIN; INSULINASE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CIRCULAR DICHROISM; ENZYME MECHANISM; GENETIC VARIABILITY; HYDROLYSIS; INHERITANCE; NONHUMAN; PRESENILE DEMENTIA; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN STRUCTURE; RAT; STROKE; WILD TYPE;

AMYLOID BETA-PROTEIN; ANIMALS; CEREBRAL HEMORRHAGE; CEREBROVASCULAR ACCIDENT; DEMENTIA; DIMERIZATION; FAMILY HEALTH; HUMANS; INSULYSIN; PEPTIDE FRAGMENTS; RATS; RECOMBINANT PROTEINS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; VARIATION (GENETICS);

LEUCISCUS IDUS;

EID: 0037931536     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M300276200     Document Type: Article

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