Pyruvate and lactate protect striatal neurons against N-methyl-D-aspartate-induced neurotoxicity

European Journal of Neuroscience

Volumn 11, Issue 9, 1999, Pages 3215-3224

  Maus, Marion ^a   Marin, Philippe ^a   Israël, Maurice ^b   Glowinski, Jacques ^a   Prémont, Joël ^a  

^a l'alimentation et l'Environnement   (France)

^b LABORATOIRE DE NEUROBIOLOGIE CELLULAIRE ET MOLÉCULAIRE   (France)

Author keywords

ATP; Excitotoxicity; Glutamate; Mouse; ketoacid

Indexed keywords

ADENOSINE TRIPHOSPHATE; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; DIZOCILPINE; GLUTAMIC ACID; HYDROGEN PEROXIDE; LACTIC ACID; N METHYL DEXTRO ASPARTIC ACID; PYRUVIC ACID;

ANIMAL CELL; ARTICLE; BRAIN ISCHEMIA; CELL ENERGY; CONTROLLED STUDY; DECARBOXYLATION; EXTRACELLULAR MATRIX; GLYCOLYSIS; NERVE CELL NECROSIS; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; STRIATE CORTEX;

EID: 0032850167     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9568.1999.00745.x     Document Type: Article

References (46)

1. Ankarcrona, M., Dypbukt, J.M., Bonfoco, E., Zhivotovsky, B., Orrenius, S., Lipton, S.A. & Nicotera, P. (1995) Glutamate-induced neuronal death: a succession of necrosis and apoptosis depending on mitochondrial function. Neuron, 15, 961-973.
2. Benveniste, H., Drejer, J., Schousboe, A. & Diemer, N.H. (1984) Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia by intracerebral microdialysis. J. Neurochem., 43, 1369-1374.
3. Choi, D.W. (1988) Glutamate neurotoxicity and diseases of the central nervous system. Neuron, 1, 623-634.
4. Conn, A.R., Fell, D.I. & Steele, R.D. (1983) Characterization of α-keto acid transport across blood-brain barrier in rats. Am. J. Physiol., 245, 253-260.
5. Coyle, J.T. & Puttfarcken, P. (1993) Oxidative stress, glutamate, and neurodegenerative disorders. Science, 262, 689-695.
6. Dawson, V.L., Dawson, T.M., Bartley, D.A., Uhl, G.R. & Snyder, S.H. (1993) Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures. J. Neurosci., 13, 2651-2661.
7. Dawson, V.L., Dawson, T.M., London, E.D., Bredt, D.S. & Snyder, S.H. (1991) Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures. Proc. Natl Acad. Sci. USA, 88, 6368-6371.
8. Denizot, F. & Lang, R. (1986) Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability. J. Immunol. Meth., 89, 271-277.
9. Desagher, S., Glowinski, J. & Premont, J. (1997) Pyruvate protects neurons against hydrogen peroxide-induced toxicity. J. Neurosci., 17, 9060-9067.
10. Dijkstra, U., Gabreëls, F., Joosten, E., Wevers, R., Lamers, K., Doesburg, W. & Renier, W. (1984) Friedreich's ataxia: intravenous pyruvate load to demonstrate a defect in pyruvate metabolism. Neurology, 34, 1493-1497.
11. Dringen, R., Wiesinger, H. & Hamprecht, B. (1993) Uptake of L-lactate by cultured rat brain neurons. Neurosci. Lett., 163, 5-7.
12. Dugan, L.L., Sensi, S.L., Canzoniero, L.M.T., Hadran, S.D., Rothman, S.M., Lin, T.S., Goldberg, M.P. & Choi, D.W. (1995) Mitochondrial production of reactive oxygen species in cortical neurons following exposure to N-methyl-D-aspartate. J. Neurosci., 15, 6377-6388.
13. 2+ after toxic NMDA-receptor activity. J. Neurochem., 65, 739-743.
14. Goldberg, M.P. & Choi, D.W. (1993) Combined oxygen and glucose deprivation in cortical cell culture: calcium-dependent and calcium-independent mechanisms in neuronal injury. J. Neurosci., 13, 3510-3524.
15. 2+ indicators with greatly improved fluorescence properties. J. Biol. Chem., 260, 3440-3450.
16. Hartley, D.M. & Choi, D.W. (1989) Delayed rescue of N-methyl-D-aspartate receptor-mediated neuronal injury in cortical culture. J. Pharmacol. Exp. Ther., 250, 752-758.
17. Israël, M., Lesbat, B. & Bruner, J. (1993) Glutamate and acetylcholine release from cholinergic nerve terminals, a calcium control of the specificity of the release mechanism. Neurochem. Int., 22, 53-58.
18. Izumi, Y., Benz, A.M., Zorumski, C.F. & Olney, J.W. (1994) Effects of lactate and pyruvate on glucose deprivation in rat hippocampal slices. Neuroreport, 5, 617-620.
19. Kiedrowski, L. & Costa, E. (1995) Glutamate-induced destabilization of intracellular calcium concentration homeostasis in cultured cerebellar granule cells: role of mitochondria in calcium buffering. Mol. Pharmacol., 47, 140-147.
20. Kiedrowski, L., Wroblewski, J.T. & Costa, E. (1994) Intracellular sodium concentration in cultured cerebellar granule cells challenged with glutamate. Mol. Pharmacol., 45, 1050-1054.
21. Koh, J.Y., Goldberg, M.P., Hartley, D.M. & Choi, D.W. (1990) Non-NMDA receptor-mediated neurotoxicity in cortical culture. J. Neurosci., 10, 693-705.
22. Lafon-Cazal, M., Pietri, S., Culcasi, M. & Bockaert, J. (1993) NMDA-dependent superoxide production and neurotoxicity. Nature, 364, 535-537.
23. Marin, P., Maus, M., Desagher, S., Glowinski, J. & Prémont, J. (1995) Nicotine protects cultured striatal neurons against N-methyl-D-aspartate receptor-mediated neurotoxicity. Neuroreport, 5, 1977-1980.
24. 2+ concentration and neurotoxicity, and increase antioxidant enzyme activities in hippocampal neurons. J. Neurochem., 65, 1740-1751.
25. Monaghan, D.T., Bridges, R.J. & Cotman, C.W. (1989) The excitatory amino acid receptors: their classes, pharmacology and distinct properties in the function of the central nervous system. Annu. Rev. Toxicol., 29, 365-402.
26. 2+ in mouse striatal neurons? Eur. J. Neurosci., 6, 854-860.
27. Oldendorf, W.H. (1973) Carrier-mediated blood-brain barrier transport of short chain monocarboxylic organic acids. Am. J. Physiol., 224, 1450-1453.
28. Paoletti, P. & Ascher, P. (1994) Mechanosensitivity of NMDA receptors in cultured mouse central neurons. Neuron, 13, 645-655.
29. Pellerin, L. & Magistretti, P.J. (1994) Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization. Proc. Natl Acad. Sci. USA, 91, 10625-10629.
30. Poitry-yamate, C.L., Poitry, S. & Tsacopoulos, M. (1995) Lactate release by Müller cells is metabolised by photoreceptors from mammalian retina. J. Neurosci., 15, 5179-5191.
31. Rothman, S.M. & Olney, J.W. (1986) Glutamate and the pathophysiology of hypoxic-ischemic brain damage. Ann. Neurol., 19, 105-111.
32. Schinder, A.F., Olson, E.C., Spitzer, N.C. & Montai, M. (1996) Mitochondrial dysfunction is a primary event in glutamate neurotoxicity. J. Neurosci., 16, 6125-6133.
33. + channels, glutamate release, and NMDA receptors mediates delayed neurodegeneration through nitric oxide formation. J. Neurosci., 16, 5004-5013.
34. Théry, C., Chamak, B. & Mallat, M. (1991) Cytotoxic effect of brain macrophages on developing neurons. Eur. J. Neurosci., 3, 1155-1164.
35. Tsacopoulos, M. & Magistretti, P.J. (1996) Metabolic coupling between glia and neurons. J. Neurosci., 16, 877-885.
36. Vornov, J.J. (1995) Toxic NMDA-receptor activation occurs during recovery in a tissue culture model of ischemia. J. Neurochem., 65, 1681-1691.
37. Weiss, S., Pin, J.P., Sebben, M., Kemp, D.E., Sladeczek, F., Gabrion, J. & Bockaert, J. (1986) Synaptogenesis of cultured striatal neurons in serum-free medium: a morphological and biochemical study. Proc. Natl Acad. Sci., USA, 83, 2238-2242.
38. White, L.E., Hodges, H.D., Carnes, K.M., Price, J.L. & Dubinski, J.M. (1994) Colocalization of excitatory and inhibitory neurotransmitter markers in striatal projection neurons in the rat. J. Comp. Neurol., 339, 328-340.
39. White, R.J. & Reynolds, I.J. (1996) Mitochondrial depolarization in glutamate-stimulated neurons: an early signal specific to excitotoxin exposure. J. Neurosci., 15, 5688-5697.
40. Williams, R.J., Murphy, N., Glowinski, J. & Premont, J. (1996a) Glucose regulates glutamate-evoked arachidonic acid release from cultured striatal neurons. J. Neurochem., 65, 241-249.
41. Williams, R.J., Maus, M., Stella, N., Glowinski, J. & Premont, J. (1996b) Reduced glucose metabolism enhances the glutamate-evoked release of arachidonic acid from striatal neurons. Neuroscience, 74, 461-468.
42. Wu, T.W., Fung, K.P., Zeng, L., Wu, J. & Nakamura, H. (1994) Propyl gallate as a hepatoprotector in vitro and in vivo. Biochem. Pharmacol., 48, 419-422.
43. Yamada, K.A. & Tang, C.M. (1993) Benzothiadiazides inhibit rapid glutamate receptor desensitization and enhance glutamatergic synaptic currents. J. Neurosci., 13, 3904-3915.
44. 2+ exchange currents in cortical neurons: concomitant forward and reverse operation and effect of glutamate. Eur. J. Neurosci., 9, 1273-1281.
45. Zhang, J., Dawson, V.L., Dawson, T.M. & Snyder, S.H. (1994) Nitric oxide activation of poly (ADP-ribose) synthetase in neurotoxicity. Science, 263, 687-689.
46. Zorumski, C.F., Thio, L.L., Clark, G.D. & Clifford, D.B. (1990) Blockade of desensitisation augments quisqualate excitotoxicity in hippocampal neurons. Neuron, 5, 61-66.