Ubiquitin in chains

Trends in Biochemical Sciences

Volumn 25, Issue 11, 2000, Pages 544-548

  Pickart, Cecile M ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

POLYUBIQUITIN; PROTEASOME; UBIQUITIN;

MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; REACTION ANALYSIS; REGULATORY MECHANISM; REVIEW; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS;

BIOPOLYMERS; CYSTEINE ENDOPEPTIDASES; MULTIENZYME COMPLEXES; POLYUBIQUITIN; PROTEASOME ENDOPEPTIDASE COMPLEX; SIGNAL TRANSDUCTION; UBIQUITINS;

EUKARYOTA;

EID: 0034327504     PISSN: 09680004     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0004(00)01681-9     Document Type: Review

References (43)

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6. The structure of ClpP at 2.3 Å resolution suggests a model for ATP-dependent proteolysis
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8. Active site mutants in the six regulatory particle ATPases reveal multiple roles for ATP in the proteasome
9. The base of the proteasome regulatory particle exhibits chaperone-like activity
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13. Proteasomal turnover of p21(Cip1) does not require p21(Cip1) ubiquitination
14. A proteasome howdunit: The case of the missing signal
15. Occurrence of a polyubiquitin structure in ubiquitin-protein conjugates
16. A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein
17. Inhibition of proteolysis and cell cycle progression in a multiubiquitination-deficient yeast mutant
18. Recognition of the polyubiquitin proteolytic signal
19. Inhibition of the 26S proteasome by polyubiquitin chains synthesized to have defined lengths
20. Surface hydrophobic residues of multiubiquitin chains essential for proteolytic targeting
21. The hydrophobic effect contributes to polyubiquitin chain recognition
22. Structure of tetraubiquitin shows how multiubiquitin chains can be formed
23. A 26S protease subunit that binds ubiquitin conjugates
24. Arabidopsis MBP1 gene encodes a conserved ubiquitin recognition component of the 26S proteasome
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26. Multiubiquitin chain binding and protein degradation are mediated by distinct domains within the 26S proteasome subunit Mcb1
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32. The deubiquitinating enzymes
33. A function for monoubiquitination in the internalization of a G protein-coupled receptor
34. Monoubiquitin carries a novel internalization signal that is appended to activated receptors
35. A ubiquitin mutant with specific defects in DNA repair and multiubiquitination
36. Stress resistance in Saccharomyces cerevisiae is strongly correlated with assembly of a novel type of multiubiquitin chain
37. A role for ubiquitination in mitochondrial inheritance in Saccharomyces cerevisiae
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39. Cell cycle-regulated modification of the ribosome by a variant multiubiquitin chain
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43. Physical association of ubiquitin ligases and the 26S proteasome