Expression of the Huntingtin-associated protein 1 gene in the developing and adult mouse

Neuroscience Letters

Volumn 282, Issue 1-2, 2000, Pages 37-40

  Dragatsis, Ioannis ^a   Dietrich, Paula ^a   Zeitlin, Scott ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

Brain; Embryo; Enteric neurons; Hap1; Hypothalamus; Mouse; Pituitary; Testis

Indexed keywords

PROTEIN;

ANIMAL TISSUE; ARTICLE; BRAIN; CONTROLLED STUDY; DEVELOPMENT; EMBRYO; GENE EXPRESSION; HISTOCHEMISTRY; HUNTINGTON CHOREA; HYPOPHYSIS; HYPOTHALAMUS; IN SITU HYBRIDIZATION; INTESTINE INNERVATION; MOUSE; NERVE CELL; NEUROEPITHELIUM; NONHUMAN; NORTHERN BLOTTING; OVARY; PRIORITY JOURNAL; SPINAL CORD; SYMPATHETIC GANGLION; TESTIS;

ANIMALS; BLOTTING, NORTHERN; EMBRYO; EMBRYONIC AND FETAL DEVELOPMENT; IN SITU HYBRIDIZATION; MICE; MICE, INBRED C57BL; NERVE TISSUE PROTEINS; ORGAN SPECIFICITY;

EID: 0034677858     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(00)00872-7     Document Type: Article

References (14)

1. Block-Galarza J., Chase K.O., Sapp E., Vaughn K.T., Vallee R.B., DiFiglia M., Aronin N. Fast transport and retrograde movement of huntingtin and HAP1 in axons. NeuroReport. 8:1997;2247-2251.
2. Colomer B., Engelender S., Sharp A.H., Duan K., Cooper J.K., Lanahan A., Lyford G., Worley P., Ross C.A. Huntingtin-associated protein 1 (HAP1) binds to a Trio-like polypeptide, with a rac1 guanine nucleotide exchange factor domain. Hum. Mol. Genet. 6:1997;1519-1525.
3. Dragatsis I., Efstratiadis A., Zeitlin S. Mouse mutant embryos lacking huntingtin are rescued from lethality by wild-type extraembryonic tissues. Development. 125:1998;1529-1539.
4. Engelender S., Sharp A.H., Colomer V., Tokito M.K., Lanahan A., Worley P., Holzbaur E.L., Ross C.A. Huntingtin-associated protein 1 (HAP1) interacts with the p150 Glued subunit of dynactin. Hum. Mol. Genet. 6:1997;2205-2212.
5. Gutekunst C.A., Li S.H., Yi H., Ferrante R.J., Li X.J., Hersch S.M. The cellular and subcellular localization of huntingtin-associated protein 1 (HAP1): comparison with huntingtin in rat and human. J. Neurosci. 18:1998;7674-7686.
6. Li X.J., Li S.H., Sharp A.H., Nucifora F.C. Jr, Schilling G., Lanahan A., Worley P., Snyder S.H., Ross C.A. A huntingtin-associated protein enriched in brain with implications for pathology. Nature. 378:1995;398-402.
7. Li X.J., Sharp A.H., Li S.H., Dawson T.M., Snyder S.H., Ross C.A. Huntingtin-associated protein (HAP1): discrete neuronal localizations in the brain resemble those of neuronal nitric oxide synthase. Proc. Natl. Acad. Sci. USA. 93:1996;4839-4844.
8. Li S.H., Gutekunst C.A., Hersch S.M., Li X.J. Association of HAP1 isoforms with a unique cytoplasmic structure. J. Neurochem. 71:1998;2178-2185.
9. Li S.H., Gutekunst C.A., Hersch S.M., Li X.J. Interaction of huntingtin-associated protein with dynactin P150 Glued. J. Neurosci. 18:1998;1261-1269.
10. Martin E.J., Kim M., Velier J., Sapp E., Lee H.S., Laforet G., Won L., Chase K., Bhide P.G., Heller A., Aronin N., Difiglia M. Analysis of Huntingtin-associated protein 1 in mouse brain and immortalized striatal neurons. J. Comp. Neurol. 403:1999;421-430.
11. Nasir J., Duan K., Nichol K., Engelender S., Ashworth R., Colomer V., Thomas S., Disteche C.M., Hayden M.R., Ross C.A. Gene structure and map location of the murine homolog of the Huntington-associated protein HAP1. Mamm. Genome. 9:1998;565-570.
12. Nasir J., Maclean A., Engelender S., Duan K., Margolis R.L., Kleiderlein J.J., Ross C.A., Hayden M.R. Chromosomal localization of the Huntingtin associated protein (HAP-1) gene in mouse and humans with radiation hybrid and interspecific backcross mapping. Mamm. Genome. 10:1999;397-398.
13. Page K.J., Potter L., Aronni S., Everitt B.J., Dunnett S.B. The expression of Huntingtin-associated protein (HAP1) mRNA in developing, adult and ageing rat CNS: implications for Huntington's disease neuropathology. Eur. J. Neurosci. 10:1998;1835-1845.
14. Wilkinson D.G. Whole mount in situ hybridization of vertebrate embryos. Wilkinson D.G. In Situ Hybridization: A Practical Approach. 1992;75-84 IRL Press, Oxford.