Genetics of Parkinson's disease

Annals of Neurology

Volumn 44, Issue 3 SUPPL. 1, 1998, Pages

  Gasser, Thomas ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOSOMAL DOMINANT DISORDER; CHROMOSOME 2P; CHROMOSOME 4Q; CLINICAL RESEARCH; CONFERENCE PAPER; GENE LOCUS; GENE MUTATION; HUMAN; LEWY BODY; PARKINSON DISEASE; PATHOGENESIS; PRIORITY JOURNAL;

EID: 0031670136     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/ana.410440708     Document Type: Conference Paper

References (41)

1. Payami H, Larsen K, Bernard S, Nutt J. Increased risk of Parkinson's disease in parents and siblings of patients. Ann Neurol 1994;36:659-661
2. Vieregge P, Heberlein I. Increased risk of Parkinson's disease in relatives of patients [letter]. Ann Neurol 1995;37:685
3. Bonifati V, Fabrizio E, Vanacore N, De Mari M, Meco G. Familial Parkinson's disease: a clinical genetic analysis. Can J Neurol Sci 1995;22:272-279
4. De Michele G, Filla A, Volpe G, et al. Environmental and genetic risk factors in Parkinson's disease: a case-control study in southern Italy. Mov Disord 1996;11:17-23
5. Marder K, Tang MX, Mejia H, et al. Risk of Parkinson's disease among first-degree relatives: a community-based study. Neurology 1996;47:155-160
6. Lazzarini AM, Myers RH, Zimmerman TR Jr, et al. A clinical genetic study of Parkinson's disease: evidence for dominant transmission. Neurology 1994;44:499-506
7. Farrer LA, O'Sullivan DM, Cupples LA, Growdon JH, Myers RH. Assessment of genetic risk for Alzheimer's disease among first-degree relatives. Ann Neurol 1989;25:485-493
8. Ward CD, Duvoisin RC, Ince SE, et al. Parkinson's disease in twins. Adv Neurol 1984;40:341-344
9. Vieregge P, Schiffke KA, Friedrich HJ, Muller B, Ludin HP. Parkinson's disease in twins. Neurology 1992;42:1453-1461
10. Marttila RJ, Kaprio J, Koskenvuo M, Rinne UK. Parkinson's disease in a nationwide twin cohort. Neurology 1988;38:1217-1219
11. Bharucha NE, Stokes L, Schoenberg BS, et al. A case-control study of twin pairs discordant for Parkinson's disease: a search for environmental risk factors. Neurology 1986;36:284-288
12. Burn DJ, Mark MH, Playford ED, et al. Parkinson's disease in twins studied with 18F-dopa and positron emission tomography. Neurology 1992;42:1894-1900
13. Piccini P, Morrish PK, Turjanski N, et al. Dopaminergic function in familial Parkinson's disease: a clinical and 18F-dopa positron emission tomography study. Ann Neurol 1997;41: 222-229
14. Perry TL, Wright JM, Berry K, Hansen S, Perry TL Jr. Dominantly inherited apathy, central hypoventilation, and Parkinson's syndrome: clinical, biochemical, and neuropathologic studies of 2 new cases. Neurology 1990;40:1882-1887
15. Purdy A, Hahn A, Barnett HJ, et al. Familial fatal Parkinsonism with alveolar hypoventilation and mental depression. Ann Neurol 1979;6:523-531
16. Perry TL, Bratty PJ, Hansen S, Kennedy J, Urquhart N, Dolman CL. Hereditary mental depression and Parkinsonism with taurine deficiency. Arch Neurol 1975;32:108-113
17. Bhatia KP, Daniel SE, Marsden CD. Familial parkinsonism with depression: a clinicopathological study. Ann Neurol 1993; 34:842-847
18. Matsumine H, Saito M, Shimoda Matsubayashi S, et al. Localization of a gene for an autosomal recessive form of juvenile Parkinsonism to chromosome 6q25.2-27. Am J Hum Genet 1997;60:588-596
19. Wszolek ZK, Pfeiffer RF, Bhatt MH, et al. Rapidly progressive autosomal dominant parkinsonism and dementia with pallido-ponto-nigral degeneration. Ann Neurol 1992;32:312-320
20. Wilhelmsen KC, Wszolek ZK. Is there a genetic susceptibility to idiopathic parkinsonism? Parkinsonism Relat Disord 1995;1: 73-84
21. Wijker M, Wszolek ZK, Wolters EC, et al. Localization of the gene for rapidly progressive autosomal dominant parkinsonism and dementia with pallido-ponto-nigral degeneration to chromosome 17q21. Hum Mol Genet 1996;5:151-154
22. Wszolek ZK, Cordes M, Calne DB, Munter MD, Cordes I, Pfeifer RF. Hereditary Parkinson disease: report of 3 families with dominant autosomal inheritance. Nervenarzt 1993;64: 331-335
23. Golbe LI, Di Iorio G, Sanges G, et al. Clinical genetic analysis of Parkinson's disease in the Contursi kindred [abstract]. Ann Neurol 1996;40:767-775
24. Markopoulou K, Wszolek ZK, Pfeiffer RF. A Greek-American kindred with autosomal dominant, levodopa-responsive parkinsonism and anticipation. Ann Neurol 1995;38:373-378
25. Wszolek ZK, Pfeiffer B, Fulgham JR, et al. Western Nebraska family (family D) with autosomal dominant parkinsonism. Neurology 1995;45:502-505
26. Polymeropoulos MH, Higgins JJ, Golbe LI, et al. Mapping of a gene for Parkinson's disease to chromosome 4q21-q23. Science 1996;274:1197-1199
27. Di Rocco A, Molinari SP, Kollmeier B, Yahr MD. Parkinson's disease: progression and mortality in the L-DOPA era. Adv Neurol 1996;69:3-11
28. Golbe LI, Di Iorio G, Bonavita V, Miller DC, Duvoisin RC. A large kindred with autosomal dominant Parkinson's disease. Ann Neurol 1990;27:276-282
29. Gasser T, Müller-Myhsok B, Wszolek Z, et al. Genetic complexity and Parkinson's disease. Science 1997;277:388-389
30. Denson MA, Wszolek ZK. Familial parkinsonism: our experience and a review of the literature. Parkinsonism Relat Disord 1995;1:35-46
31. Bonifati V, Fabrizio E, Vanacore N, Gasparini M, Meco G. A large Italian family with dominantly inherited levodopa-responsive parkinsonism and isolated tremors [abstract]. Mov Disord 1996:11(Suppl 1):86
32. Mazzerti P, Le Guern E, Bonnet AM, Vidailhet M, Brice A, Agid Y. Familial Parkinson's disease and polymorphism at the CYP2D6 locus [letter]. J Neurol Neurosurg Psychiatry 1994; 57:871-872
33. Scott WK, Stajich JM, Yamaoka L, et al. Genetic complexity in Parkinson's disease. Science 1997;277:387-388
34. Vaughan JR, Durr A, Gasser T, et al. The α-synuclein Ala53Thr mutation is not a common cause of familial Parkinson's disease: a study of 230 European cases. Neurology 1998 [in press]
35. Chan P, Tanner CM, Jiang X, Langston JW. Failure to find the alpha-synuclein gene missense mutation (G209A) in 100 patients with younger onset Parkinson's disease. Neurology 1998; 50:513-514
36. Vaughan JR, Farrer M, Wszolek EK, et al. Sequencing of the alpha-synuclein gene in a large series of families with familial Parkinson's disease fails to reveal any further mutations. Hum Mol Genet 1998;7:751-753
37. Spillantini MG, Schmidt ML, Lee VM, Troianowski JQ, Jakes R, Goedert M. Alpha-synuclein in Lewy bodies. Nature 1997; 388:839-840
38. Krüger R, Kuhn W, Müller T, et al. Ala39Pro mutation in the gene encoding α-synuclein in Parkinson's disease. Nature Genet 1998;18:106-108
39. Gasser T, Müller-Myhsok B, Wszolek ZK, et al. A susceptibility locus for Parkinson's disease maps to chromosome 2p13. Nature Genet 1998;18:262-265
40. Lander ES, Schork NJ. Generic dissection of complex traits. Science 1994;265:2037-2048
41. Strittmatter WJ, Saunders AM, Schmechel D, et al. Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc Natl Acad Sci USA 1993;90:1977-1981