Up-regulation of TNF-α convertase (TACE/ADAM17) after oxygen-glucose deprivation in rat forebrain slices

Neuropharmacology

Volumn 40, Issue 8, 2001, Pages 1094-1102

  Hurtado, Olivia ^a   Cárdenas, Antonio ^a   Lizasoain, Ignacio ^a   Boscá, Lisardo ^b   Leza, Juan C ^a   Lorenzo, Pedro ^a   Moro, María A ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b CSIC   (Spain)

Author keywords

Cytokines; Disintegrin; Ischemia; Metalloproteinase; Nitric oxide; Stroke

Indexed keywords

BB 3103; BISINDOLYLMALEIMIDE; CYCLOHEXIMIDE; GLUCOSE; METALLOPROTEINASE INHIBITOR; NITRIC OXIDE SYNTHASE; OXYGEN; PROTEIN KINASE C; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; BRAIN SLICE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVITY; FOREBRAIN; HYPOGLYCEMIA; HYPOXEMIA; IC 50; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ADAM PROTEINS; ANIMALS; BRAIN ISCHEMIA; CELL HYPOXIA; GLUCOSE; HYDROXAMIC ACIDS; MALE; METALLOENDOPEPTIDASES; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; OXYGEN; PROSENCEPHALON; PROTEASE INHIBITORS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0034986981     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(01)00035-1     Document Type: Article

References (48)

1. Beta-amyloid stimulation of inducible nitric-oxide synthase in astrocytes is interleukin-1beta- and tumor necrosis factor-alpha (TNFalpha)-dependent, and involves a TNFalpha receptor-associated factor- and NFkappaB-inducing kinase-dependent signaling mechanism
2. Involvement of the membrane form of tumour necrosis factor-α in lipopolysaccharide-induced priming of mouse peritoneal macrophages for enhanced nitric oxide response to lipopolysaccharide
3. Diverse cell surface protein ectodomains are shed by a system sensitive to metalloprotease inhibitors
4. A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells
5. ADAMs: Focus on the protease domain
6. Metalloprotease-disintegrins: Links to cell adhesion and cleavage of TNFα and Notch
7. Expression of tumor necrosis factor alpha after focal cerebral ischaemia in the rat
8. Evidence that tumor necrosis factor alpha converting enzyme is involved in regulated α-secretase cleavage of the Alzheimer amyloid protein precursor
9. Neuroprotective effect of N-(3-(aminomethyl benzyl) acetamidine, an inducible nitric oxide synthase inhibitor, in brain slices exposed to oxygen-glucose deprivation
10. Implication of glutamate in the expression of inducible nitric oxide synthase after oxygen and glucose deprivation in rat forebrain slices
11. Down-regulation of neuronal NO synthase by NO after oxygen-glucose deprivation in rat forebrain slices
12. Release of TNFα in the rat hippocampus following epileptic seizures and excitotoxic neuronal damage
13. Stimulation-induced down-regulation of tumor necrosis factor-α converting enzyme
14. The role of cytokines in the neuropathology of stroke and trauma
15. TNF-α processing enzyme inhibitors prevent aspirin-induced TNF-α release and protect against gastric mucosal injury in rats
16. Induction of calcium-independent nitric oxide synthase activity in primary rat glial cultures
17. Processing of tumour necrosis factor-α precursor by metalloproteinases
18. Protein determination using bicinchoninic acid in the presence of sulfhydryl reagents
19. Membrane protein secretases
20. The role of proteolysis in Alzheimer's disease
21. Delayed reduction of ischemic brain injury and neurological deficits in mice lacking the inducible nitric oxide synthase gene
22. Metalloprotease-disintegrin (ADAM) genes are widely and differentially expressed in the adult CNS
23. Adamalysins. A family of metzincins including TNF-α converting enzyme (TACE)
24. Constitutive and regulated α-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloprotease
25. Tumor necrosis factor-alpha expression in ischemic neurons
26. Nitric oxide and peroxynitrite exert distinct effects on mitochondrial respiration which are differentially blocked by glutathione or glucose
27. Regulation of tumour necrosis factor-α processing by a metalloproteinase inhibitor
28. Pro-tumour necrosis factor-α processing activity is tightly controlled by a component that does not affect notch processing
29. Involvement of a metalloprotease in the shedding of human neutrophil Fc gammaRIIIB
30. Specific sequence elements are required for the expression of functional tumor necrosis factor-α-converting enzyme (TACE)
31. Expression of inducible nitric oxide synthase by neurons following exposure to endotoxin and cytokine
32. In vivo expression of inducible nitric oxide synthase in cerebellar neurons
33. Neuronal expression of inducible nitric oxide synthase after oxygen and glucose deprivation in rat forebrain slices
34. Neuronal death induced by SIN-1 in the presence of superoxide dismutase: Protection by cyclic GMP
35. Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-α
36. The secretases that cleave angiotensin converting enzyme and the amyloid precursor protein are distinct from tumour necrosis factor-α convertase
37. An essential role for ectodomain shedding in mammalian development
38. Nitric oxide production and neurotoxicity mediated by activated microglia from human versus mouse brain
39. Functional analysis of the domain structure of tumor necrosis factor-alpha converting enzyme
40. Sequential induction of nitric oxide synthase by Corynebacterium parvum in different organs of the mouse
41. Identification and characterization of a pro-tumor necrosis factor-α-processing enzyme from the ADAM family of zinc metalloproteases
42. 2+-independent nitric oxide synthases
43. Intracellular maturation and localization of the tumour necrosis factor α convertase (TACE)
44. Cytokines regulate L-arginine-dependent cyclic GMP production in rat glial cells
45. Induction of nitric oxide synthase in glial cells
46. Neuronal and inducible nitric oxide synthase and nitrotyrosine immunoreactivities in the cerebral cortex of the aging rat
47. Processing and release of tumor necrosis factor α
48. ADAMs in fertilization and development