Anoxic depolarization mediates acute damage independent of glutamate in neocortical brain slices

Cerebral Cortex

Volumn 11, Issue 3, 2001, Pages 249-259

  Jarvis, C R ^a   Anderson, T R ^a   Andrew, R D ^a  

^a QUEEN S UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; GLUCOSE; GLUTAMATE RECEPTOR; GLUTAMATE RECEPTOR ANTAGONIST; GLUTAMIC ACID; KYNURENIC ACID; OXYGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN HYPOXIA; BRAIN ISCHEMIA; BRAIN METABOLISM; BRAIN SLICE; CONTROLLED STUDY; DEPOLARIZATION; EVOKED RESPONSE; GRAY MATTER; LIGHT SCATTERING; MALE; MIGRAINE; NEOCORTEX; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; STRESS;

EID: 0035094866     PISSN: 10473211     EISSN: None     Source Type: Journal    
DOI: 10.1093/cercor/11.3.249     Document Type: Article

References (63)

1. NMDA antagonists: Lack of protective effects against hypoxic damage in CA1 region of hippocampal slices
2. Similar propagation of SD and hypoxic SD-like depolarization in rat hippocampus recorded optically and electrically
3. Use of intrinsic optical signals to monitor physiological changes in brain tissue slices
4. Imaging repetitive spreading depression in submerged neocortical slices
5. Sigma receptor ligands block spreading depression in rat neocortical slices
6. Imaging cell volume changes and neuronal excitation in the hippocampal slice
7. Imaging NMDA- and kainate-induced intrinsic optical signals from hippocampal slice
8. Evidence against volume regulation by cortical brain cells during acute osmotic stress
9. Potential sources of intrinsic optical signals imaged in live brain slices
10. Induction of spreading depression in the ischemic hemisphere following experimental middle cerebral artery occlusion: Effect on infarct morphology
11. Studies on anoxic depolarization
12. +) ATPase with ouabain induces spreading depression-like depolarization in hippocampal slices
13. Imaging spreading depression and associated intracellular calcium waves in brain slices
14. Temperature modulation of cerebral depolarization during focal cerebral ischemia in rats: Correlation with ischemic injury
15. Postischemic hypothermia: A critical appraisal with implications for clinical treatment
16. The problem of assessing effective neuroprotection in experimental cerebral ischemia
17. Persistent neuroprotection with prolonged postischemic hypothermia in adult rats subjected to transient middle cerebral artery acclusion
18. Brain damage and temperature: Cellular and molecular mechanisms
19. Cortical spreading depression induces an LTP-like effect in rat neocortex in vivo
20. Spontaneous neurological recovery after stroke and the fate of the ischemic penumbra
21. Effect of anoxia on ion distribution in the brain
22. Systemic ketamine blocks cortical spreading depression but does not delay the onset of terminal anoxic depression
23. Functional and morphological changes induced by transient in vivo ischemia
24. Glutamate-mediated injury in focal cerebral ischemia: The excitotoxic hypothesis revised
25. Periinfarct depolarizations
26. Spreading depression waves as mediators of secondary injury and protective mechanisms
27. Spreading depression mediates acute neuronal damage induced by oxygen/glucose deprivation in neocortical slices
28. Interpretation of intrinsic optical signals and calcein fluorescence during acute excitotoxic insult in the hippocampal slice
29. Role of calcium channels in spreading depression in rat hippocampal slices
30. Glial ion transport and volume control
31. Regional differences in hypoxic depolarization and swelling in hippocampal slices
32. Cerebral blood flow in migraine and cortical spreading depression
33. The effect of glutamate receptor blockade on anoxic depolarisation and cortical spreading depression
34. Spreading depression of activity in the cerebral cortex
35. Further observations on the spreading depression of activity in the cerebral cortex
36. Imaging of synaptically evoked intrinsic optical signals in hippocampal slices
37. Evidence for a role of the NMDA receptor in cortical spreading depression in the rat
38. Physiological and pathophysiological roles of excitatory amino acids during central neurons system development
39. Prevention of periinfarct direct current shifts with glutamate antagonist NBQX following occlusion of the middle cerebral artery in the rat
40. Spreading depression as a contributor to ischemic brain damage
41. Spreading depression is not associated with neuronal injury in the normal brain
42. Characterization of cortical depolarizations evoked in focal cerebral ischemia
43. NMDA-receptor blockers but not NBQX, an AMPA-receptor antagonist, inhibit spreading depression in the rat brain
44. The behavior of extracellular ions during spreading depression
45. Spreading depression determines acute cellular damage in the hippocampal slice during oxygen/glucose deprivation
46. 2/glucose deprivation in the hippocampal slice
47. The ischemic penumbra: Twenty years on
48. High extracellular glutamate and neuronal death in neurological disorders: Cause, contribution, or consequence
49. Altered glutamatergic transmission in neurological disorders: From high extracellular glutamate to excessive synaptic efficacy
50. Is high extracellular glutamate the key to excitotoxicity in traumatic brain injury?
51. Rapid alterations in dendrite morphology during sublethal hypoxia or glutamate receptor activation
52. Intrinsic optical signaling denoting neuronal damage in response to acute excitotoxic insult in the hippocampal slice
53. Furosemide inhibits regenerative cortical spreading depression in anaesthetized cats
54. Glutamate release in severe brain ischemia is mainly by reversed uptake
55. Factors influencing the frequency of fluorescence transients as markers of peri-infarct depolarizations in focal cerebral ischemia
56. Mechanisms of spreading depression: A review of recent findings and a hypothesis
57. The role of spreading depression in focal ischemia evaluated by diffusion mapping
58. Hypothermia reduces the propensity of cortical tissue to propagate direct current depolarization in the rat
59. Oxygen/glucose deprivation in hippocampal slices: Altered intraneuronal elemental composition predicts structural and functional damage
60. Use and abuse of tissue cultures in neurotoxicity studies
61. + uptake in cultured astrocytes
62. Intense furosemide-sensitive potassium accumulation in astrocytes in the presence of pathologically high extracellular potassium levels
63. Damage from oxygen and glucose deprivation in hippocampal slices is prevented by tetrodotoxin, lidocaine and phenytoin without blockade of action potentials