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Volumn 21, Issue 2, 1997, Pages 121-128

Mechanisms that result in damage during and following cerebral ischemia

Author keywords

Acidosis; Adenosine; Apoptosis; Calcium; Free radicals; Glutamate; Hypoxia; Inflammation; Necrosis; Neuronal rescue; Nutrition; Spreading depression; Stroke

Indexed keywords

ADENOSINE; ANTIOXIDANT; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM ION; FREE RADICAL; GLUTAMIC ACID; MONOAMINE OXIDASE INHIBITOR; REACTIVE OXYGEN METABOLITE; SELEGILINE; TIRILAZAD;

EID: 0031041262     PISSN: 01497634     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0149-7634(96)00001-2     Document Type: Article
Times cited : (92)

References (78)
  • 1
    • 0027078124 scopus 로고
    • Energy requirements of CNS cells as related to their function and to their vulnerability to ischemia: A commentary based on studies on retina
    • Ames, A. Energy requirements of CNS cells as related to their function and to their vulnerability to ischemia: a commentary based on studies on retina. Can. J. Physiol. Pharmac. 70:S158-164; 1992.
    • (1992) Can. J. Physiol. Pharmac. , vol.70
    • Ames, A.1
  • 2
    • 0028328642 scopus 로고
    • Pharmacological profile of a novel neuronal calcium channel blocker includes reduced cerebral damage and neurological deficits in rat focal ischemia
    • Barone F.C., Prince W.J., Jakobsen P., Sheardown M.J., Feuerstein G. Pharmacological profile of a novel neuronal calcium channel blocker includes reduced cerebral damage and neurological deficits in rat focal ischemia. Pharmac. Biochem. Behav. 48:1994;77-85.
    • (1994) Pharmac. Biochem. Behav. , vol.48 , pp. 77-85
    • Barone, F.C.1    Prince, W.J.2    Jakobsen, P.3    Sheardown, M.J.4    Feuerstein, G.5
  • 4
    • 0028941909 scopus 로고
    • Mechanisms of delayed cell death following hypoxic-ischemic injury in the immature rat: Evidence for apoptosis during selective neuronal loss
    • Beilharz E.J., Williams C.E., Dragunow M., Sirimanne E.S., Gluckman P.D. Mechanisms of delayed cell death following hypoxic-ischemic injury in the immature rat: evidence for apoptosis during selective neuronal loss. Molec. Brain Res. 29:1995;1-14.
    • (1995) Molec. Brain Res. , vol.29 , pp. 1-14
    • Beilharz, E.J.1    Williams, C.E.2    Dragunow, M.3    Sirimanne, E.S.4    Gluckman, P.D.5
  • 5
    • 0029078778 scopus 로고
    • The hematopoietic cytokine, colony-stimulating factor 1, is also a growth factor in the CNS; Congenital absence of CSF-1 in mice results in abnormal microglial response and increased neuron vulnerability to injury
    • Berezovskaya O., Maysinger D., Fedoroff S. The hematopoietic cytokine, colony-stimulating factor 1, is also a growth factor in the CNS; congenital absence of CSF-1 in mice results in abnormal microglial response and increased neuron vulnerability to injury. Int. J. Dev. Neurosci. 13:1995;285-299.
    • (1995) Int. J. Dev. Neurosci. , vol.13 , pp. 285-299
    • Berezovskaya, O.1    Maysinger, D.2    Fedoroff, S.3
  • 6
    • 0027199345 scopus 로고
    • Inhibition of brain calcium channels by plasma proteins from anoxic turtles
    • Bickler, P.E.; Gallego, S.M. Inhibition of brain calcium channels by plasma proteins from anoxic turtles. Am. J. Physiol. 265:R277-281; 1993.
    • (1993) Am. J. Physiol. , vol.265
    • Bickler, P.E.1    Gallego, S.M.2
  • 7
    • 0028280865 scopus 로고
    • Oxygen radicals in focal cerebral ischemia
    • Chan P.H. Oxygen radicals in focal cerebral ischemia. Brain Pathol. 4:1994;59-64.
    • (1994) Brain Pathol. , vol.4 , pp. 59-64
    • Chan, P.H.1
  • 8
    • 0021363366 scopus 로고
    • Brain injury, edema, and vascular permeability changes induced by oxygen-derived free radicals
    • Chan P.H., Schmidley J.W., Fishman R.A., Longar S.M. Brain injury, edema, and vascular permeability changes induced by oxygen-derived free radicals. Neurol. 34:1984;315-320.
    • (1984) Neurol. , vol.34 , pp. 315-320
    • Chan, P.H.1    Schmidley, J.W.2    Fishman, R.A.3    Longar, S.M.4
  • 9
    • 0028799654 scopus 로고
    • Calcium: Still center-stage in hypoxic-ischemic neuronal death
    • Choi D.W. Calcium: still center-stage in hypoxic-ischemic neuronal death. Trends Neurosci. 18:1995;58-60.
    • (1995) Trends Neurosci. , vol.18 , pp. 58-60
    • Choi, D.W.1
  • 10
    • 0027231086 scopus 로고
    • Intraischemic but not postischemic brain hypothermia protects chronically following global forebrain ischemia in rats
    • Dietrich W.D., Busto R., Alonso O., Globus M.Y.T., Ginsberg M.D. Intraischemic but not postischemic brain hypothermia protects chronically following global forebrain ischemia in rats. J. Cereb. Blood Flow Metab. 13:1993;541-549.
    • (1993) J. Cereb. Blood Flow Metab. , vol.13 , pp. 541-549
    • Dietrich, W.D.1    Busto, R.2    Alonso, O.3    Globus, M.Y.T.4    Ginsberg, M.D.5
  • 11
    • 0026317327 scopus 로고
    • Channel arrest: Implications from membrane resistance in turtle neurons
    • Doll, C.J.; Hochachka, P.W.; Reiner, P.B. Channel arrest: implications from membrane resistance in turtle neurons. Am. J. Physiol. 261:R1321-1324; 1991.
    • (1991) Am. J. Physiol. , vol.261
    • Doll, C.J.1    Hochachka, P.W.2    Reiner, P.B.3
  • 12
    • 0029085179 scopus 로고
    • Hypoxia-inducible gene expression
    • Fandrey J. Hypoxia-inducible gene expression. Respir. Physiol. 101:1995;1-10.
    • (1995) Respir. Physiol. , vol.101 , pp. 1-10
    • Fandrey, J.1
  • 13
    • 0028324661 scopus 로고
    • Involvement of glutamate receptors, lipases, and phospholipases in long-term potentiation and neurodegeneration
    • Farooqui A.A., Horrocks L.A. Involvement of glutamate receptors, lipases, and phospholipases in long-term potentiation and neurodegeneration. J. Neurosci. Res. 38:1994;6-11.
    • (1994) J. Neurosci. Res. , vol.38 , pp. 6-11
    • Farooqui, A.A.1    Horrocks, L.A.2
  • 15
    • 0028842314 scopus 로고
    • Potentially effective therapies for acute ischemic stroke
    • Fisher M. Potentially effective therapies for acute ischemic stroke. Eur. Neurol. 35:1995;3-7.
    • (1995) Eur. Neurol. , vol.35 , pp. 3-7
    • Fisher, M.1
  • 17
    • 0028145984 scopus 로고
    • The ischemic penumbra, injury thresholds, and the therapeutic window for acute stroke
    • Ginsberg M.D., Pulsinelli W.A. The ischemic penumbra, injury thresholds, and the therapeutic window for acute stroke. Ann. Neurol. 36:1994;553-554.
    • (1994) Ann. Neurol. , vol.36 , pp. 553-554
    • Ginsberg, M.D.1    Pulsinelli, W.A.2
  • 19
    • 0029130550 scopus 로고
    • Glutamate release and free radical production following brain injury: Effects of posttraumatic hypothermia
    • Globus M.Y.T., Alonso O., Dietrich W.D., Busto R., Ginsberg M.D. Glutamate release and free radical production following brain injury: effects of posttraumatic hypothermia. J. Neurochem. 65:1995;1704-1711.
    • (1995) J. Neurochem. , vol.65 , pp. 1704-1711
    • Globus, M.Y.T.1    Alonso, O.2    Dietrich, W.D.3    Busto, R.4    Ginsberg, M.D.5
  • 20
    • 0028222573 scopus 로고
    • Ischaemia-reperfusion injury
    • Grace P.A. Ischaemia-reperfusion injury. Br. J. Surg. 81:1994;637-647.
    • (1994) Br. J. Surg. , vol.81 , pp. 637-647
    • Grace, P.A.1
  • 21
    • 0023492685 scopus 로고
    • The cerebral ischemic penumbra
    • Hakim, A.M. The cerebral ischemic penumbra. Can. J. Neurol. Sci. 557-559; 1987.
    • (1987) Can. J. Neurol. Sci. , pp. 557-559
    • Hakim, A.M.1
  • 22
    • 0027196356 scopus 로고
    • Cerebral ischaemia, free radicals and antioxidant protection
    • Hall E.D. Cerebral ischaemia, free radicals and antioxidant protection. Biochem. Soc. Trans. 21:1993;334-339.
    • (1993) Biochem. Soc. Trans. , vol.21 , pp. 334-339
    • Hall, E.D.1
  • 23
    • 0028187682 scopus 로고
    • Therapeutic potential of the lazaroids (21-aminosteroids) in acute central nervous system trauma, ischemia and subarachnoid hemorrhage
    • Hall E.D., McCall J.M., Means E.D. Therapeutic potential of the lazaroids (21-aminosteroids) in acute central nervous system trauma, ischemia and subarachnoid hemorrhage. Adv. Pharmac. 28:1994;221-268.
    • (1994) Adv. Pharmac. , vol.28 , pp. 221-268
    • Hall, E.D.1    McCall, J.M.2    Means, E.D.3
  • 24
    • 0028933896 scopus 로고
    • DNA fragmentation indicative of apoptosis following unilateral cerebral hypoxia-ischemia in the neonatal rat
    • Hill I.E., Macmanus J.P., Rasquinha I., Tuor U.I. DNA fragmentation indicative of apoptosis following unilateral cerebral hypoxia-ischemia in the neonatal rat. Brain Res. 676:1995;398-403.
    • (1995) Brain Res. , vol.676 , pp. 398-403
    • Hill, I.E.1    Macmanus, J.P.2    Rasquinha, I.3    Tuor, U.I.4
  • 25
    • 0027982679 scopus 로고
    • Viability thresholds and the penumbra of focal ischemia
    • Hossmann K.-A. Viability thresholds and the penumbra of focal ischemia. Ann. Neurol. 36:1994;557-565.
    • (1994) Ann. Neurol. , vol.36 , pp. 557-565
    • Hossmann, K.-A.1
  • 26
    • 0028271350 scopus 로고
    • Glutamate-mediated injury in focal cerebral ischemia - The excitotoxin hypothesis revised
    • Hossmann K.-A. Glutamate-mediated injury in focal cerebral ischemia - the excitotoxin hypothesis revised. Brain Pathol. 4:1994;23-36.
    • (1994) Brain Pathol. , vol.4 , pp. 23-36
    • Hossmann, K.-A.1
  • 27
    • 0028889831 scopus 로고
    • Oligodendroglial precursor cell susceptibility to hypoxia is related to poor ability to cope with reactive oxygen species
    • Husain J., Juurlink B.H.J. Oligodendroglial precursor cell susceptibility to hypoxia is related to poor ability to cope with reactive oxygen species. Brain Res. 698:1995;86-94.
    • (1995) Brain Res. , vol.698 , pp. 86-94
    • Husain, J.1    Juurlink, B.H.J.2
  • 28
    • 0027467906 scopus 로고
    • Ischemia-induced death of astrocytes and neurons in primary culture: Pitfalls in quantifying neuronal cell death
    • Juurlink B.H.J., Hertz L. Ischemia-induced death of astrocytes and neurons in primary culture: pitfalls in quantifying neuronal cell death. Dev. Brain Res. 71:1993;239-246.
    • (1993) Dev. Brain Res. , vol.71 , pp. 239-246
    • Juurlink, B.H.J.1    Hertz, L.2
  • 29
    • 0028243698 scopus 로고
    • A randomized, double-blind, placebo-controlled trial of nimodipine in acute ischemic hemispheric stroke
    • Kaste M., Fogelholm R., Erilä T., Palomäki H., Murros K., Rissanen A., Sarna S. A randomized, double-blind, placebo-controlled trial of nimodipine in acute ischemic hemispheric stroke. Stroke. 25:1994;1348-1353.
    • (1994) Stroke , vol.25 , pp. 1348-1353
    • Kaste, M.1    Fogelholm, R.2    Erilä, T.3    Palomäki, H.4    Murros, K.5    Rissanen, A.6    Sarna, S.7
  • 30
    • 0028235436 scopus 로고
    • Visualization of DNA double strand breaks in the gerbil hippocampal CA1 following transient ischemia
    • Kihara S., Shiraishi T., Nakagawa S., Toda K., Tabuchi K. Visualization of DNA double strand breaks in the gerbil hippocampal CA1 following transient ischemia. Neurosci. Lett. 175:1994;133-136.
    • (1994) Neurosci. Lett. , vol.175 , pp. 133-136
    • Kihara, S.1    Shiraishi, T.2    Nakagawa, S.3    Toda, K.4    Tabuchi, K.5
  • 32
    • 0028982658 scopus 로고
    • L-deprenyl reduces brain damage in rats exposed to transient hypoxia-ischemia
    • Knollema S., Aukema W., Hom H., Korf J., Terhorst G.J. L-deprenyl reduces brain damage in rats exposed to transient hypoxia-ischemia. Stroke. 26:1995;1883-1887.
    • (1995) Stroke , vol.26 , pp. 1883-1887
    • Knollema, S.1    Aukema, W.2    Hom, H.3    Korf, J.4    Terhorst, G.J.5
  • 33
    • 0028248463 scopus 로고
    • Epidemiology of stroke: Methods and trends
    • Kurtzke J.F. Epidemiology of stroke: methods and trends. Statistics Canada Health Reports. 6:1994;13-19.
    • (1994) Statistics Canada Health Reports , vol.6 , pp. 13-19
    • Kurtzke, J.F.1
  • 34
    • 0028762647 scopus 로고
    • Excitatory amino acids as a final common pathway for neurologic disorders
    • Lipton S.A., Rosenberg P.A. Excitatory amino acids as a final common pathway for neurologic disorders. N. Engl. J. Med. 330:1994;613-622.
    • (1994) N. Engl. J. Med. , vol.330 , pp. 613-622
    • Lipton, S.A.1    Rosenberg, P.A.2
  • 35
    • 0026510062 scopus 로고
    • Mechanisms for anoxic survival in the vertebrate brain
    • Lutz P.L. Mechanisms for anoxic survival in the vertebrate brain. Ann. Rev. Physiol. 54:1992;601-618.
    • (1992) Ann. Rev. Physiol. , vol.54 , pp. 601-618
    • Lutz, P.L.1
  • 36
    • 0029039120 scopus 로고
    • Upregulation of the GABAA/benzodiazepine receptor during anoxia in the freshwater turtle brain
    • Lutz, P.L.; Leone Kabler, S.L. Upregulation of the GABAA/benzodiazepine receptor during anoxia in the freshwater turtle brain. Am. J. Physiol. 268:R1332-1335; 1995.
    • (1995) Am. J. Physiol. , vol.268
    • Lutz, P.L.1    Leone Kabler, S.L.2
  • 37
    • 0025778517 scopus 로고
    • Monoamine oxidase inhibitors prevent striatal neuronal necrosis induced by transient forebrain ischemia
    • Matsui Y., Kumagae Y. Monoamine oxidase inhibitors prevent striatal neuronal necrosis induced by transient forebrain ischemia. Neurosci. Lett. 126:1991;175-178.
    • (1991) Neurosci. Lett. , vol.126 , pp. 175-178
    • Matsui, Y.1    Kumagae, Y.2
  • 38
    • 0026530776 scopus 로고
    • Induction of interleukin-1b mRNA in rat brain after transient forebrain ischemia
    • Minami M., Kuraishi Y., Yabuuchi K., Yamazaki A., Satoh M. Induction of interleukin-1b mRNA in rat brain after transient forebrain ischemia. J. Neurochem. 58:1992;390-392.
    • (1992) J. Neurochem. , vol.58 , pp. 390-392
    • Minami, M.1    Kuraishi, Y.2    Yabuuchi, K.3    Yamazaki, A.4    Satoh, M.5
  • 40
    • 0028897733 scopus 로고
    • Clinical experience with excitatory amino acid antagonist drugs
    • Muir K.W., Lees K.R. Clinical experience with excitatory amino acid antagonist drugs. Stroke. 26:1995;503-513.
    • (1995) Stroke , vol.26 , pp. 503-513
    • Muir, K.W.1    Lees, K.R.2
  • 41
    • 0011482066 scopus 로고
    • The turtle
    • In: Williams, O., ed. New York: Washington Square Press;
    • Nash, O. The turtle. In: Williams, O., ed. Immortal Poems. New York: Washington Square Press; 1952:571.
    • (1952) Immortal Poems , pp. 571
    • Nash, O.1
  • 43
    • 0025862308 scopus 로고
    • Release of inhibitory neurotransmitters in response to anoxia in turtle brain
    • Nilsson, G.E.; Lutz, P.L. Release of inhibitory neurotransmitters in response to anoxia in turtle brain. Am. J. Physiol. 261:R32-37; 1991.
    • (1991) Am. J. Physiol. , vol.261
    • Nilsson, G.E.1    Lutz, P.L.2
  • 44
    • 0027237324 scopus 로고
    • Role of GABA in hypoxia tolerance, metabolic depression and hibernation possible links to neurotransmitter evolution
    • Nilsson G.E., Lutz P.L. Role of GABA in hypoxia tolerance, metabolic depression and hibernation possible links to neurotransmitter evolution. Comp. Biochem. Physiol. 105C:1993;329-336.
    • (1993) Comp. Biochem. Physiol. , vol.105 , pp. 329-336
    • Nilsson, G.E.1    Lutz, P.L.2
  • 45
    • 0025923211 scopus 로고
    • Interaction between free radicals and excitatory amino acids in the formation of ischemic brain edema in rats
    • Oh S.M., Betz A.L. Interaction between free radicals and excitatory amino acids in the formation of ischemic brain edema in rats. Stroke. 22:1991;915-921.
    • (1991) Stroke , vol.22 , pp. 915-921
    • Oh, S.M.1    Betz, A.L.2
  • 46
    • 0002663558 scopus 로고
    • Cerebral edema and the blood-brain barrier
    • In: Neuwelt, E.A., ed. New York: Plenum Medical Book Company;
    • Pappius, H.M. Cerebral edema and the blood-brain barrier. In: Neuwelt, E.A., ed. Implications of the Blood-Brain Barrier and its Manipulation. Volume 1. New York: Plenum Medical Book Company; 1989:293-309.
    • (1989) Implications of the Blood-Brain Barrier and its Manipulation , vol.1 , pp. 293-309
    • Pappius, H.M.1
  • 47
    • 0026086524 scopus 로고
    • Differences in transmitter release, morphology and ischemia-induced cell injury between cerebellar granule cell cultures developing in the presence and in the absence of a depolarizing potassium concentration
    • Peng L., Juurlink B.H.J., Hertz L. Differences in transmitter release, morphology and ischemia-induced cell injury between cerebellar granule cell cultures developing in the presence and in the absence of a depolarizing potassium concentration. Devl. Brain Res. 63:1991;1-12.
    • (1991) Devl. Brain Res. , vol.63 , pp. 1-12
    • Peng, L.1    Juurlink, B.H.J.2    Hertz, L.3
  • 49
    • 0026518612 scopus 로고
    • Downregulation of sodium channels during anoxia: A putative survival strategy of turtle brain
    • Perez Pinzon, M.A.; Rosenthal, M.; Sick, T.J.; Lutz, P.L.; Pablo, J.; Mash, D. Downregulation of sodium channels during anoxia: a putative survival strategy of turtle brain. Am. J. Physiol. 262:R712-715; 1992.
    • (1992) Am. J. Physiol. , vol.262
    • Perez Pinzon, M.A.1    Rosenthal, M.2    Sick, T.J.3    Lutz, P.L.4    Pablo, J.5    Mash, D.6
  • 51
    • 0025960006 scopus 로고
    • 2+ homeostatis, cell death, proliferation and differentation
    • 2+ homeostatis, cell death, proliferation and differentation. Chem.-Biol. Interactions. 77:1991;1-23.
    • (1991) Chem.-Biol. Interactions , vol.77 , pp. 1-23
    • Richter, C.1    Kass, G.E.N.2
  • 52
    • 0024406708 scopus 로고
    • Hundred-fold increase in neuronal vulnerability to glutamate toxicity in astrocyte-poor cultures of rat cerebral cortex
    • Rosenberg P.A., Aizenman E. Hundred-fold increase in neuronal vulnerability to glutamate toxicity in astrocyte-poor cultures of rat cerebral cortex. Neurosci. Lett. 103:1989;162-168.
    • (1989) Neurosci. Lett. , vol.103 , pp. 162-168
    • Rosenberg, P.A.1    Aizenman, E.2
  • 54
    • 0027303779 scopus 로고
    • Aluminium pretreatment impairs the ability of astrocytes to protect neurons from glutamate mediated toxicity
    • Sass J.B., Ang L.-C., Juurlink B.H.J. Aluminium pretreatment impairs the ability of astrocytes to protect neurons from glutamate mediated toxicity. Brain Res. 62:1993;207-214.
    • (1993) Brain Res. , vol.62 , pp. 207-214
    • Sass, J.B.1    Ang, L.-C.2    Juurlink, B.H.J.3
  • 55
    • 0029032152 scopus 로고
    • Continuing ischemic damage after acute middle cerebral artery infarction in humans demonstrated by short-echo proton spectroscopy
    • Saunders D.E., Howe F.A., van den Boogaart A., McLean M.A., Griffiths J.R., Brown M.M. Continuing ischemic damage after acute middle cerebral artery infarction in humans demonstrated by short-echo proton spectroscopy. Stroke. 26:1995;1007-1013.
    • (1995) Stroke , vol.26 , pp. 1007-1013
    • Saunders, D.E.1    Howe, F.A.2    Van Den Boogaart, A.3    McLean, M.A.4    Griffiths, J.R.5    Brown, M.M.6
  • 56
    • 0027395275 scopus 로고
    • Metabotropic glutamate receptors in brain function and pathology
    • Schoepp D.D., Conn P.J. Metabotropic glutamate receptors in brain function and pathology. Trends Pharmac. 14:1993;13-20.
    • (1993) Trends Pharmac. , vol.14 , pp. 13-20
    • Schoepp, D.D.1    Conn, P.J.2
  • 57
    • 0027282808 scopus 로고
    • The molecular biology of the mammalian glutamate receptor channels
    • Seeburg P.H. The molecular biology of the mammalian glutamate receptor channels. Trends Pharmac. 14:1993;297-303.
    • (1993) Trends Pharmac. , vol.14 , pp. 297-303
    • Seeburg, P.H.1
  • 59
    • 0028128947 scopus 로고
    • Neuron damage induced by some potent kainoids and neuroprotective action of new agonists for metabotropic glutamate receptors
    • Shinosaki H. Neuron damage induced by some potent kainoids and neuroprotective action of new agonists for metabotropic glutamate receptors. Eur. Neuro. 34:(Suppl 3):1994;2-9.
    • (1994) Eur. Neuro. , vol.34 , Issue.SUPPL. 3 , pp. 2-9
    • Shinosaki, H.1
  • 61
    • 0028123528 scopus 로고
    • Cell death in primary cultures of mouse neurons and astrocytes during exposure to and recovery from hypoxia, substrate deprivation and simulated ischemia
    • Sochocka E., Juurlink B.H.J., Code W.E., Hertz V., Peng L., Hertz L. Cell death in primary cultures of mouse neurons and astrocytes during exposure to and recovery from hypoxia, substrate deprivation and simulated ischemia. Brain Res. 638:1994;21-28.
    • (1994) Brain Res. , vol.638 , pp. 21-28
    • Sochocka, E.1    Juurlink, B.H.J.2    Code, W.E.3    Hertz, V.4    Peng, L.5    Hertz, L.6
  • 62
    • 0029157604 scopus 로고
    • Pharmacology of sodium and calcium channel modulation in neurons: Implications for neuroprotection
    • Spedding M., Lepagnol J. Pharmacology of sodium and calcium channel modulation in neurons: implications for neuroprotection. Biochem. Soc. Trans. 23:1995;633-636.
    • (1995) Biochem. Soc. Trans. , vol.23 , pp. 633-636
    • Spedding, M.1    Lepagnol, J.2
  • 63
    • 0028929328 scopus 로고
    • Mechanisms and genes of cellular suicide
    • Steller H. Mechanisms and genes of cellular suicide. Science. 267:1995;1445-1449.
    • (1995) Science , vol.267 , pp. 1445-1449
    • Steller, H.1
  • 65
    • 0024991859 scopus 로고
    • Oxygen-derived free radicals in reperfusion injury
    • Sussman M.S., Bulkley G.B. Oxygen-derived free radicals in reperfusion injury. Meth. Enzym. 186:1990;711-723.
    • (1990) Meth. Enzym. , vol.186 , pp. 711-723
    • Sussman, M.S.1    Bulkley, G.B.2
  • 66
    • 0028906351 scopus 로고
    • Acidosis causes failure of astrocyte glutamate uptake during hypoxia
    • Swanson R.A., Farrell K., Simon R.P. Acidosis causes failure of astrocyte glutamate uptake during hypoxia. J. Cereb. Blood Flow Metab. 15:1995;417-424.
    • (1995) J. Cereb. Blood Flow Metab. , vol.15 , pp. 417-424
    • Swanson, R.A.1    Farrell, K.2    Simon, R.P.3
  • 68
    • 0027324191 scopus 로고
    • Evolving concepts about the role of acidosis in ischemic neuropathology
    • Tombaugh G.C., Sapolsky R.M. Evolving concepts about the role of acidosis in ischemic neuropathology. J. Neurochem. 61:1993;793-803.
    • (1993) J. Neurochem. , vol.61 , pp. 793-803
    • Tombaugh, G.C.1    Sapolsky, R.M.2
  • 69
    • 0027498018 scopus 로고
    • Endonuclease activation following focal ischemic injury in the rat brain
    • Tominaga T., Kure S., Narisawa K., Yoshimoto T. Endonuclease activation following focal ischemic injury in the rat brain. Brain Res. 608:1993;21-26.
    • (1993) Brain Res. , vol.608 , pp. 21-26
    • Tominaga, T.1    Kure, S.2    Narisawa, K.3    Yoshimoto, T.4
  • 70
    • 0029092217 scopus 로고
    • Inhibition of NFkB DNA binding activity by glucocorticoids in rat brain
    • Unlap T., Jope R.S. Inhibition of NFkB DNA binding activity by glucocorticoids in rat brain. Neurosci. Lett. 198:1995;41-44.
    • (1995) Neurosci. Lett. , vol.198 , pp. 41-44
    • Unlap, T.1    Jope, R.S.2
  • 72
    • 0027958345 scopus 로고
    • Sodium ion dependent transporters for neurotransmitters - A review of recent developments
    • Worrall D.M., Williams D.C. Sodium ion dependent transporters for neurotransmitters - a review of recent developments. Biochem. J. 297:1994;425-436.
    • (1994) Biochem. J. , vol.297 , pp. 425-436
    • Worrall, D.M.1    Williams, D.C.2
  • 75
    • 0027489423 scopus 로고
    • Influence of mild hypothermia on hypoxic-ischemic brain damage in the immature rat
    • Yager J., Towfighi J., Vannucci R.C. Influence of mild hypothermia on hypoxic-ischemic brain damage in the immature rat. Pediatr. Res. 34:1993;525-529.
    • (1993) Pediatr. Res. , vol.34 , pp. 525-529
    • Yager, J.1    Towfighi, J.2    Vannucci, R.C.3
  • 76
    • 0027945369 scopus 로고
    • Correlation between content of high-energy phosphates and hypoxic-ischemic damage in immature and mature astrocytes
    • Yager J.Y., Kala G., Hertz L., Juurlink B.H.J. Correlation between content of high-energy phosphates and hypoxic-ischemic damage in immature and mature astrocytes. Devel. Brain Res. 82:1994;62-68.
    • (1994) Devel. Brain Res. , vol.82 , pp. 62-68
    • Yager, J.Y.1    Kala, G.2    Hertz, L.3    Juurlink, B.H.J.4
  • 78
    • 0028128974 scopus 로고
    • Reperfusion-induced injury to the blood-brain-barrier after middle cerebral artery occlusion in rats
    • Yang G.-Y., Betz A.L. Reperfusion-induced injury to the blood-brain-barrier after middle cerebral artery occlusion in rats. Stroke. 25:1994;1658-1665.
    • (1994) Stroke , vol.25 , pp. 1658-1665
    • Yang, G.-Y.1    Betz, A.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.