Measuring human β-secretase (BACE1) activity using homogeneous time-resolved fluorescence

Analytical Biochemistry

Volumn 319, Issue 1, 2003, Pages 49-55

  Kennedy, Matthew E ^a   Wang, Wenyan ^a   Song, Lixin ^a   Lee, Julie ^a   Zhang, Lili ^a   Wong, Gwen ^a   Wang, Liyang ^a   Parker, Eric ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DEATH; ENERGY TRANSFER; EUROPIUM; EUROPIUM ALLOYS; FORSTER RESONANCE ENERGY TRANSFER; NEURODEGENERATIVE DISEASES; PEPTIDES;

ALZHEIMER'S DISEASE; CONCENTRATION-DEPENDENT; ENZYMATIC ACTIVITIES; ENZYME CONCENTRATIONS; FLUORESCENCE RESONANCE ENERGY TRANSFER; HOMOGENEOUS TIME-RESOLVED FLUORESCENCE ASSAYS; SYNTHETIC PEPTIDE; TIME-RESOLVED FLUORESCENCE;

ENZYME INHIBITION;

ALLOPHYCOCYANIN; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; ENZYME INHIBITOR; EUROPIUM; PEPTIDE DERIVATIVE; STREPTIDINE;

AMINO TERMINAL SEQUENCE; ARTICLE; BIOTINYLATION; CARBOXY TERMINAL SEQUENCE; CONCENTRATION RESPONSE; CORRELATION ANALYSIS; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PURIFICATION; FLUORESCENCE ANALYSIS; INCUBATION TIME; INTERMETHOD COMPARISON; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROCESSING;

EID: 0038729338     PISSN: 00032697     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0003-2697(03)00253-7     Document Type: Article

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