Cooperative interactions at m2 muscarinic acetylcholine receptors: Structure/activity relationships in stepwise shortened bispyridinium- and bis(ammonio)alkane-type allosteric modulators

Neurochemical Research

Volumn 28, Issue 3-4, 2003, Pages 667-673

  Gilsbach, Ralf ^a   Großmüller, Maren ^a   Alptüzün, Vildan ^b   Erciyas, Ercin ^b   Tränkle, Christian ^a   Holzgrabe, Ulrike ^c   Mohr, Klaus ^a  

^a UNIVERSITY OF BONN   (Germany)

^b EGE UNIVERSITY   (Turkey)

^c UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Allosteric interactions; Cooperativity; Muscarinic receptors; Structure activity relationships

Indexed keywords

AMMONIA; CHOLINERGIC RECEPTOR; METHYLSCOPOLAMINE; MUSCARINIC M2 RECEPTOR; PHTHALIMIDE; PYRIDINIUM DERIVATIVE; RADIOLIGAND; ALKANE; MUSCARINIC RECEPTOR;

ALLOSTERISM; ARTICLE; BINDING SITE; DISSOCIATION; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; ANIMAL; CHEMISTRY; HEART MUSCLE; HEART VENTRICLE; IN VITRO STUDY; METABOLISM; SWINE;

SUS SCROFA;

ALKANES; ALLOSTERIC REGULATION; ANIMALS; HEART VENTRICLES; MYOCARDIUM; N-METHYLSCOPOLAMINE; PYRIDINIUM COMPOUNDS; RECEPTOR, MUSCARINIC M2; RECEPTORS, MUSCARINIC; STRUCTURE-ACTIVITY RELATIONSHIP; SWINE;

EID: 0038724266     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1022858414900     Document Type: Article

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