Allosteric modulation of muscarinic receptor signaling: Alcuronium-induced conversion of pilocarpine from an agonist into an antagonist

Journal of Pharmacology and Experimental Therapeutics

Volumn 301, Issue 2, 2002, Pages 720-728

  Zahn, Katrin ^a,b   Eckstein, Niels ^a,b   Tränkle, Christian ^a,b   Sadée, Wolfgang ^a,b   Mohr, Klaus ^a,b  

^a UNIVERSITY OF BONN   (Germany)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCURONIUM; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); MUSCARINIC RECEPTOR; OXOTREMORINE; PILOCARPINE;

ALLOSTERISM; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CHO CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE RESPONSE; GUINEA PIG; HEART ATRIUM CONTRACTION; LIGAND BINDING; MODULATION; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING;

ALCURONIUM; ALLOSTERIC REGULATION; ANIMALS; ATRIAL FUNCTION; CHO CELLS; CRICETINAE; DRUG INTERACTIONS; GTP-BINDING PROTEINS; HEART ATRIA; MUSCARINIC AGONISTS; MUSCARINIC ANTAGONISTS; PILOCARPINE; RECEPTOR, MUSCARINIC M2; RECEPTORS, MUSCARINIC; SIGNAL TRANSDUCTION; TRANSFECTION; VASOCONSTRICTION;

EID: 0036232127     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.301.2.720     Document Type: Article

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