-
1
-
-
0028256010
-
A stable and highly potent hexamethonium derivative which modulates muscarinic receptors allosterically in guinea-pig hearts
-
BEJEUHR, G., BLASCHKE, G., HOLZGRABE, U., MOHR, K., SÜRIG, U. AND TERFLOTH, G.: A stable and highly potent hexamethonium derivative which modulates muscarinic receptors allosterically in guinea-pig hearts. J. Pharm. Pharmacol. 46: 108-112, 1994.
-
(1994)
J. Pharm. Pharmacol.
, vol.46
, pp. 108-112
-
-
Bejeuhr, G.1
Blaschke, G.2
Holzgrabe, U.3
Mohr, K.4
Sürig, U.5
Terfloth, G.6
-
2
-
-
0002597710
-
Molecular modelling and synthesis of potent stabilizers of antagonist binding to M-cholinoceptors
-
BEJEUHR, G., HOLZGRABE, U., MOHR, K., SÜRIG, U. AND VON PETERSENN, A.: Molecular modelling and synthesis of potent stabilizers of antagonist binding to M-cholinoceptors. Pharm. Pharmacol. Lett. 2: 100-103, 1992.
-
(1992)
Pharm. Pharmacol. Lett.
, vol.2
, pp. 100-103
-
-
Bejeuhr, G.1
Holzgrabe, U.2
Mohr, K.3
Sürig, U.4
Von Petersenn, A.5
-
3
-
-
0039906179
-
A second drug-binding site on muscarinic receptors
-
BIRDSALL, N. J. M., HULME, E. C., KROEMER, W. AND STOCKTON, J. M.: A second drug-binding site on muscarinic receptors. Fed. Proc. 46: 2525-2527, 1987.
-
(1987)
Fed. Proc.
, vol.46
, pp. 2525-2527
-
-
Birdsall, N.J.M.1
Hulme, E.C.2
Kroemer, W.3
Stockton, J.M.4
-
4
-
-
0028334668
-
Search for the pharmacophore of bispyridinium-type allosteric modulators of muscarinic receptors
-
BOTERO CID, H. B., HOLZGRABE, U., KOSTENIS, E., MOHR, M. AND TRÄNKLE, C.: Search for the pharmacophore of bispyridinium-type allosteric modulators of muscarinic receptors, J. Med. Chem. 37: 1439-1445, 1994.
-
(1994)
J. Med. Chem.
, vol.37
, pp. 1439-1445
-
-
Botero Cid, H.B.1
Holzgrabe, U.2
Kostenis, E.3
Mohr, M.4
Tränkle, C.5
-
6
-
-
0024566786
-
Characterisation of the antimuscarinic effect of heptane-1,7-bis-(dimethyl-3′-phthalimidopropyl ammonium bromide)
-
CHOO, L. K. AND MITCHELSON, F.: Characterisation of the antimuscarinic effect of heptane-1,7-bis-(dimethyl-3′-phthalimidopropyl ammonium bromide). Eur. J. Pharmacol. 162: 429-435, 1989.
-
(1989)
Eur. J. Pharmacol.
, vol.162
, pp. 429-435
-
-
Choo, L.K.1
Mitchelson, F.2
-
8
-
-
0017105216
-
The inhibitory effect of gallamine on muscarinic receptors
-
CLARK, A. L. AND MITCHELSON, F.: The inhibitory effect of gallamine on muscarinic receptors. Br. J. Pharmacol. 58: 323-331, 1976.
-
(1976)
Br. J. Pharmacol.
, vol.58
, pp. 323-331
-
-
Clark, A.L.1
Mitchelson, F.2
-
10
-
-
0027054955
-
Two allosteric modulators interact at a common site on cardiac muscarinic receptors
-
ELLIS, J. AND SEIDENBERG, M.: Two allosteric modulators interact at a common site on cardiac muscarinic receptors. Mol. Pharmacol. 42: 638-641, 1992.
-
(1992)
Mol. Pharmacol.
, vol.42
, pp. 638-641
-
-
Ellis, J.1
Seidenberg, M.2
-
11
-
-
0027172276
-
Use of chimeric muscarinic receptors to investigate epitopes involved in allosteric interactions
-
ELLIS, J., SEIDENBERG, M. AND BRANN, M. R.: Use of chimeric muscarinic receptors to investigate epitopes involved in allosteric interactions. Mol. Pharmacol. 44: 583-588, 1993.
-
(1993)
Mol. Pharmacol.
, vol.44
, pp. 583-588
-
-
Ellis, J.1
Seidenberg, M.2
Brann, M.R.3
-
12
-
-
0023615428
-
Verapamil interaction with the muscarinic receptor: Stereoselectivity at two sites
-
GERRY, R. H., RAUCH, B., COLVIN, R. A., ADLER, P. A. N. AND MESSINO, F. C.: Verapamil interaction with the muscarinic receptor: Stereoselectivity at two sites. Biochem. Pharmacol. 36: 2951-2956, 1987.
-
(1987)
Biochem. Pharmacol.
, vol.36
, pp. 2951-2956
-
-
Gerry, R.H.1
Rauch, B.2
Colvin, R.A.3
Adler, P.A.N.4
Messino, F.C.5
-
13
-
-
0023858688
-
Binding and functional characterization of the cardioselective muscarinic antagonist methoctramine
-
GIRALDO, E., MICHELETTI, R., MONTAGNA, E., GIACHETTI, A., VIGANO, M. A., LADINSKY, M. AND MELCHIORRE, C.: Binding and functional characterization of the cardioselective muscarinic antagonist methoctramine. J. Pharmacol. Exp. Ther. 244: 1016-1020, 1988.
-
(1988)
J. Pharmacol. Exp. Ther.
, vol.244
, pp. 1016-1020
-
-
Giraldo, E.1
Micheletti, R.2
Montagna, E.3
Giachetti, A.4
Vigano, M.A.5
Ladinsky, M.6
Melchiorre, C.7
-
14
-
-
0030240344
-
Conformational analysis, molecular shape comparison, and pharmacophore identification of different allosteric modulators of muscarinic receptors
-
in press
-
HOLZGRABE, U. AND HOPFINGER, A. J.: Conformational analysis, molecular shape comparison, and pharmacophore identification of different allosteric modulators of muscarinic receptors. J. Chem. Inf. Comput. Sci., in press, 1996.
-
(1996)
J. Chem. Inf. Comput. Sci.
-
-
Holzgrabe, U.1
Hopfinger, A.J.2
-
15
-
-
0030207040
-
Comparison of structurally different allosteric modulators of muscarinic receptors by self-organizing neural networks
-
in press
-
HOLZGRABE, U., WAGNER, M. AND GASTEIGER, J.: Comparison of structurally different allosteric modulators of muscarinic receptors by self-organizing neural networks. J. Mol. Graphics, in press, 1996.
-
(1996)
J. Mol. Graphics
-
-
Holzgrabe, U.1
Wagner, M.2
Gasteiger, J.3
-
17
-
-
0023819931
-
3H]-N-methylscopolamine binding in guinea pig myocardium by an antidote against organophosphate intoxication
-
3H]-N-methylscopolamine binding in guinea pig myocardium by an antidote against organophosphate intoxication. Pharmacol. Toxicol. 63: 163-168, 1988.
-
(1988)
Pharmacol. Toxicol.
, vol.63
, pp. 163-168
-
-
Jepsen, K.1
Lüllmann, H.2
Mohr, K.3
Pfeffer, J.4
-
18
-
-
0014313280
-
Action of atropine and some hexane-1,6-bis-ammonium derivatives upon the toxicity of DFP in mice
-
KORDS, H., LÜLLMANN, H., OHNESORGE, F. K. AND WASSERMANN, O.: Action of atropine and some hexane-1,6-bis-ammonium derivatives upon the toxicity of DFP in mice. Eur. J. Pharmacol. 3: 341-346, 1968.
-
(1968)
Eur. J. Pharmacol.
, vol.3
, pp. 341-346
-
-
Kords, H.1
Lüllmann, H.2
Ohnesorge, F.K.3
Wassermann, O.4
-
19
-
-
0000246198
-
Evidence for a multiple binding mode of bispyridinium-type allosteric modulators of muscarinic receptors
-
in press
-
KOSTENIS, E., BOTERO CID, H. M., HOLZGRABE, U. AND MOHR, K.: Evidence for a multiple binding mode of bispyridinium-type allosteric modulators of muscarinic receptors. Eur. J. Pharmacol., in press, 1996.
-
(1996)
Eur. J. Pharmacol.
-
-
Kostenis, E.1
Botero Cid, H.M.2
Holzgrabe, U.3
Mohr, K.4
-
20
-
-
0028603576
-
2-receptors of derivatives of the alkane-bis-ammonium compound W84: Comparison with bispyridinium-type allosteric modulators
-
2-receptors of derivatives of the alkane-bis-ammonium compound W84: Comparison with bispyridinium-type allosteric modulators. Eur. J. Med. Chem. 29: 947-953, 1994.
-
(1994)
Eur. J. Med. Chem.
, vol.29
, pp. 947-953
-
-
Kostenis, E.1
Holzgrabe, U.2
Mohr, K.3
-
21
-
-
0030218059
-
Two-point kinetic experiments to quantify allosteric effects on radioligand dissociation
-
KOSTENIS, E. AND MOHR, K.: Two-point kinetic experiments to quantify allosteric effects on radioligand dissociation. Trends Pharmacol. Sci. 17: 280-283, 1996.
-
(1996)
Trends Pharmacol. Sci.
, vol.17
, pp. 280-283
-
-
Kostenis, E.1
Mohr, K.2
-
22
-
-
0029126526
-
Detection and verification of allosteric interactions of agents with labeled and unlabeled ligands at G protein-coupled receptors: Interaction of strychnine and acetylcholine at muscarinic receptors
-
LAZARENO, S. AND BIRDSALL, N. J. M.: Detection and verification of allosteric interactions of agents with labeled and unlabeled ligands at G protein-coupled receptors: Interaction of strychnine and acetylcholine at muscarinic receptors. Mol. Pharmacol. 48: 362-378, 1995.
-
(1995)
Mol. Pharmacol.
, vol.48
, pp. 362-378
-
-
Lazareno, S.1
Birdsall, N.J.M.2
-
23
-
-
0023811642
-
Influence of ligand choice on the apparent binding profile of gallamine to cardiac muscarinic receptors: Identification of three main types of gallamine-muscarinic receptor interaction
-
LEE, N. H. AND EL-FAKAHANY, E. E.: Influence of ligand choice on the apparent binding profile of gallamine to cardiac muscarinic receptors: Identification of three main types of gallamine-muscarinic receptor interaction. J. Pharmacol. Exp. Ther. 246: 829-838, 1988.
-
(1988)
J. Pharmacol. Exp. Ther.
, vol.246
, pp. 829-838
-
-
Lee, N.H.1
El-Fakahany, E.E.2
-
24
-
-
0025875643
-
Allosteric antagonists of the muscarinic acetylcholine receptor
-
LEE, N. H. AND EL-FAKAHANY, E. E.: Allosteric antagonists of the muscarinic acetylcholine receptor. Biochem. Pharmacol. 42: 199-205, 1991a.
-
(1991)
Biochem. Pharmacol.
, vol.42
, pp. 199-205
-
-
Lee, N.H.1
El-Fakahany, E.E.2
-
26
-
-
71849104860
-
Protein measurement with the Folin phenol reagent
-
LOWRY, O. H., ROSEBROUGH, N. J., FARR, A. L. AND RANDALL, R. J.: Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193: 265-275, 1951.
-
(1951)
J. Biol. Chem.
, vol.193
, pp. 265-275
-
-
Lowry, O.H.1
Rosebrough, N.J.2
Farr, A.L.3
Randall, R.J.4
-
27
-
-
0014449606
-
Inhibition of the actions of carbachol and DFP on guinea pig isolated atria by alkane-bis-ammonium compounds
-
LÜLLMANN, H., OHNESORGE, F. K., SCHAUWECKER, G. C. AND WASSERMANN, O.: Inhibition of the actions of carbachol and DFP on guinea pig isolated atria by alkane-bis-ammonium compounds. Eur. J. Pharmacol. 6: 241-247, 1969.
-
(1969)
Eur. J. Pharmacol.
, vol.6
, pp. 241-247
-
-
Lüllmann, H.1
Ohnesorge, F.K.2
Schauwecker, G.C.3
Wassermann, O.4
-
28
-
-
0028942099
-
Potentiation by alcuronium of the antimuscarinic effect of N-methylscopolamine in guinea pig left atria
-
MAAß, A., KOSTENIS, E. AND MOHR, K.: Potentiation by alcuronium of the antimuscarinic effect of N-methylscopolamine in guinea pig left atria. Eur. J. Pharmacol. 272: 103-106, 1994.
-
(1994)
Eur. J. Pharmacol.
, vol.272
, pp. 103-106
-
-
Maaß, A.1
Kostenis, E.2
Mohr, K.3
-
29
-
-
0043278932
-
Opposite effects of alcuronium on agonist and antagonist binding to muscarinic receptors
-
MAAß, A. AND MOHR, K.: Opposite effects of alcuronium on agonist and antagonist binding to muscarinic receptors. Eur. J. Pharmacol., 305: 231-234, 1996.
-
(1996)
Eur. J. Pharmacol.
, vol.305
, pp. 231-234
-
-
Maaß, A.1
Mohr, K.2
-
30
-
-
0016759245
-
Antimuscarinic action of an alkane-bis-ammonium compound alone and in combination with (+)-benzetimide
-
MITCHELSON, F.: Antimuscarinic action of an alkane-bis-ammonium compound alone and in combination with (+)-benzetimide. Eur. J. Pharmacol. 33: 237-245, 1975.
-
(1975)
Eur. J. Pharmacol.
, vol.33
, pp. 237-245
-
-
Mitchelson, F.1
-
32
-
-
0026568619
-
3H]NMS-binding to cardiac muscarinic receptors from guinea pig, rat, and pig
-
3H]NMS-binding to cardiac muscarinic receptors from guinea pig, rat, and pig. Pharmacol. Toxicol. 70: 198-200, 1992.
-
(1992)
Pharmacol. Toxicol.
, vol.70
, pp. 198-200
-
-
Mohr, K.1
Staschen, C.M.2
Ziegenhagen, M.3
-
34
-
-
0022636518
-
Stabilization of antagonist binding to cardiac muscarinic acetylcholine receptors by gallamine and other neuromuscular blocking agents
-
NEDOMA, J., TUČEK, S., DANILOV, A. F. AND SHELKOVNIKOV, S. A.: Stabilization of antagonist binding to cardiac muscarinic acetylcholine receptors by gallamine and other neuromuscular blocking agents. J. Pharmacol. Exp. Ther. 236: 219-223, 1986.
-
(1986)
J. Pharmacol. Exp. Ther.
, vol.236
, pp. 219-223
-
-
Nedoma, J.1
Tuček, S.2
Danilov, A.F.3
Shelkovnikov, S.A.4
-
36
-
-
0028231689
-
Mechanisms of steric and cooperative actions of alcuronium on cardiac muscarinic acetylcholine receptors
-
PROŠKA, J. AND TUČEK, S.: Mechanisms of steric and cooperative actions of alcuronium on cardiac muscarinic acetylcholine receptors. Mol. Pharmacol. 45: 709-717, 1994.
-
(1994)
Mol. Pharmacol.
, vol.45
, pp. 709-717
-
-
Proška, J.1
Tuček, S.2
-
37
-
-
0028840330
-
Competition between positive and negative allosteric effectors on muscarinic receptors
-
PROŠKA, J. AND TUČEK, S.: Competition between positive and negative allosteric effectors on muscarinic receptors. Mol. Pharmacol. 48: 696-702, 1995.
-
(1995)
Mol. Pharmacol.
, vol.48
, pp. 696-702
-
-
Proška, J.1
Tuček, S.2
-
38
-
-
12644282489
-
The allosteric effect of W84 on muscarinic receptors is weakly temperature dependent
-
STASCHEN, C. M.: The allosteric effect of W84 on muscarinic receptors is weakly temperature dependent. Naunyn-Schmiedebergs Arch. Pharmacol. 343: suppl., R91, 1991.
-
(1991)
Naunyn-Schmiedebergs Arch. Pharmacol.
, vol.343
, Issue.SUPPL.
-
-
Staschen, C.M.1
-
39
-
-
0020533362
-
Modification of the binding properties of muscarinic receptors by gallamine
-
STOCKTON, J. M., BIRDSALL, N. J. M., BURGEN, A. S. V. AND HULME, E. C.: Modification of the binding properties of muscarinic receptors by gallamine. Mol. Pharmacol. 23: 551-557, 1983.
-
(1983)
Mol. Pharmacol.
, vol.23
, pp. 551-557
-
-
Stockton, J.M.1
Birdsall, N.J.M.2
Burgen, A.S.V.3
Hulme, E.C.4
-
41
-
-
0025203309
-
Positive cooperativity in the binding of alcuronium and N-methylscopolamine to muscarinic acetylcholine receptors
-
TUČEK, S., MUSÍLKOVÁ, J., NEDOMA, J., PROŠKA, J., SHELKOVNIKOV, S. AND VORLÍČEK, J.: Positive cooperativity in the binding of alcuronium and N-methylscopolamine to muscarinic acetylcholine receptors. Mol. Pharmacol. 38: 674-680, 1990.
-
(1990)
Mol. Pharmacol.
, vol.38
, pp. 674-680
-
-
Tuček, S.1
Musílková, J.2
Nedoma, J.3
Proška, J.4
Shelkovnikov, S.5
Vorlíček, J.6
-
42
-
-
0029055030
-
Allosteric modulation of muscarinic acetylcholine receptors
-
TUČEK, S. AND PROŠKA, J.: Allosteric modulation of muscarinic acetylcholine receptors. Trends Pharmacol. Sci. 16: 205-212, 1995.
-
(1995)
Trends Pharmacol. Sci.
, vol.16
, pp. 205-212
-
-
Tuček, S.1
Proška, J.2
-
43
-
-
0028062082
-
Identification of drugs competing with d-tubocurarine for an allosteric site on cardiac muscarinic receptors
-
WAELBROECK, M.: Identification of drugs competing with d-tubocurarine for an allosteric site on cardiac muscarinic receptors. Mol. Pharmacol. 46: 685-692, 1994.
-
(1994)
Mol. Pharmacol.
, vol.46
, pp. 685-692
-
-
Waelbroeck, M.1
-
45
-
-
0021266466
-
Inhibitory effects of quinidine on rat heart muscarinic receptors
-
WAELBROECK, M., DE NEEF, P., ROBBERECHT, P. AND CHRISTOPHE, J.: Inhibitory effects of quinidine on rat heart muscarinic receptors. Life Sci. 35: 1069-1076, 1984a.
-
(1984)
Life Sci.
, vol.35
, pp. 1069-1076
-
-
Waelbroeck, M.1
De Neef, P.2
Robberecht, P.3
Christophe, J.4
-
46
-
-
0021263814
-
Effects of verapamil on the binding properties of rat heart muscarinic receptors: Evidence for an allosteric site
-
WAELBROECK, M., ROBBERECHT, P., DE NEEF, P. AND CHRISTOPHE, J.: Effects of verapamil on the binding properties of rat heart muscarinic receptors: Evidence for an allosteric site. Biochem. Biophys. Res. Commun. 121: 340-345, 1984b.
-
(1984)
Biochem. Biophys. Res. Commun.
, vol.121
, pp. 340-345
-
-
Waelbroeck, M.1
Robberecht, P.2
De Neef, P.3
Christophe, J.4
-
47
-
-
0023802955
-
Effects of d-tubocurarine on rat cardiac muscarinic receptors: A comparison with gallamine
-
WAELBROECK, M., ROBBERECHT, P., DE NEEF, P. AND CHRISTOPHE, J.: Effects of d-tubocurarine on rat cardiac muscarinic receptors: A comparison with gallamine. J. Recept. Res. 8: 787-808, 1988.
-
(1988)
J. Recept. Res.
, vol.8
, pp. 787-808
-
-
Waelbroeck, M.1
Robberecht, P.2
De Neef, P.3
Christophe, J.4
|