The effects of brucine and alcuronium on the inhibition of [3H]acetylcholine release from rat striatum by muscarinic receptor agonists

British Journal of Pharmacology

Volumn 124, Issue 6, 1998, Pages 1213-1218

  Doležal, Vladimír ^a   Tuček, Stanislav ^a  

^a INSTITUTE OF PHYSIOLOGY   (Czech Republic)

Author keywords

Acetylcholine release; Alcuronium; Allosteric modulation; Brucine; Cholinergic neurons; Muscarinic receptors; Presynaptic autoreceptors; Striatum

Indexed keywords

ACETYLCHOLINE; ALCURONIUM; BETHANECHOL; BRUCINE; FURTRETHONIUM; MUSCARINIC AGENT; MUSCARINIC RECEPTOR; OXOTREMORINE M; TRITIUM;

ACETYLCHOLINE RELEASE; ALLOSTERISM; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CONTROLLED STUDY; CORPUS STRIATUM; DRUG EFFECT; MALE; NONHUMAN; PRIORITY JOURNAL; RADIOASSAY; RAT;

ACETYLCHOLINE; ALCURONIUM; ANIMALS; BETHANECHOL; CORPUS STRIATUM; HUMANS; MALE; MUSCARINIC AGONISTS; OXOTREMORINE; QUATERNARY AMMONIUM COMPOUNDS; RATS; RATS, WISTAR; STRYCHNINE; TRITIUM;

EID: 0031876072     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701966     Document Type: Article

References (42)

1. 2 through a correlation of in vivo microdialysis and in vitro receptor binding data. J. Pharmacol. Exp. Ther., 273, 273-279.
2. BIRDSALL, N.J.M., FARRIES, T., GHARAGOZLOO, P., KOBAYASHI, S., KUONEN, D., LAZARENO, S., POPHAM, A. & SUGIMOTO, M. (1997). Selective allosteric enhancement of the binding and actions of acetylcholine at muscarinic receptor subtypes. Life Sci., 60, 1047-1052.
3. BUCKLEY, N.J., BONNER, T.I. & BRANN, M.R. (1988). Localization of a family of muscarinic receptor mRNAs in rat brain. J. Neurosci., 8, 4646-4652.
4. CLARK, A.L. & MITCHELSON, F. (1976). The inhibitory effect of gallamine on muscarinic receptors. Br. J. Pharmacol., 58, 323-331.
5. 2 receptor-mediated inhibition of acetylcholine release in rabbit striatum. Naunyn-Schmiedeberg's Arch. Pharmacol., 345, 16-20.
6. DOLEŽAL, V. & TUČEK, S. (1983). The effects of 4-aminopyridine and tetrodotoxin on the release of acetylcholine from rat striatal slices. Naunyn-Schmiedeherg's Arch. Pharmacol., 323, 90-95.
7. DOLEŽAL, V., TUČEK, S. & HYNIE, S. (1989). Effects of pertussis toxin suggest a role for G-proteins in the inhibition of acetylcholine release from rat myenteric plexus by opioid and presynaptic muscarinic receptors. Eur. J. Neurosci., 1, 127-131.
8. DOLEŽAL, V. & TUČEK, S. (1990). Effects of atropine on the release of newly synthesized acetylcholine from rat striatal slices at various concentrations of calcium ions. Neurochem. Res., 15, 41-45.
9. 2+ absence, d-tubocurarine and vesamicol on spontaneous acetylcholine release from rat muscle. J. Physiol., 458, 1-9.
10. + concentrations. Naunyn-Schmiedeberg's Arch. Pharmacol., 348, 228-233.
11. DOLEŽAL, V. & WECKER, L. (1990). Muscarinic receptor blockade increases basal acetylcholine release from striatal slices. J. Pharmacol. Exp. Ther., 252, 739-743.
12. 2 dopamine receptor mediated inhibition of acetylcholine release in rat striatum: indications for a common signal transduction pathway. Neuroscience, 37, 1-9.
13. FONNUM, F. (1969). Isolation of choline esters from aqueous solution by extraction with sodium tetraphenylboron in organic solvents. Biochem. J., 113, 291-298.
14. GUO, Z.D., KAMEYAMA, K., RINKEN, A. & HAGA, T. (1995). Ligand binding properties of muscarinic acetylcholine receptor subtypes (m1-m5) expressed in baculovirus-infected insect cells. J. Pharmacol. Exp. Ther., 274, 378-384.
15. HERSCH, S.M., GUTEKUNST, C.-A., REES, H.D., HEILMAN, C.J. & LEVEY, A.I. (1994). Distribution of m1-m4 muscarinic receptor proteins in the rat striatum: light and electron microscopic immunocytochemistry using subtype-specific antibodies. J. Neurosci., 14, 3351-3363.
16. ILLES, P. (1986). Mechanisms of receptor-mediated modulation of transmitter release in noradrenergic, cholinergic and sensory neurones. Neuroscience, 17, 909-928.
17. 5 muscarinic acetylcholine receptors. J. Pharmacol. Exp. Ther., 274, 1077-1083.
18. JAKUBÍK, J., BAČÁKOVÁ, L., EL-FAKAHANY, E.E. & TUČEK, S. (1997). Positive cooperativity of acetylcholine and other agonists with allosteric ligands on muscarinic acetylcholine receptors. Mol. Pharmacol., 52, 172-179.
19. JAKUBÍK, J. & TUČEK, S. (1994a). Protection by alcuronium of muscarinic receptors against chemical inactivation and location of the allosteric binding site for alcuronium. J. Neurochem., 63, 1932-1940.
20. JAKUBÍK, J. & TUČEK, S. (1994b). Two populations of muscarinic binding sites in the chick heart distinguished by affinities for ligands and selective inactivation. Br. J. Pharmacol., 113, 1529-1537.
21. JAMES, M.K. & CUBEDDU, L.X. (1984). Frequency-dependent muscarinic receptor modulation of acetylcholine and dopamine release from rabbit striatum. J. Pharmacol. Exp. Ther., 229, 98-104.
22. 2 muscarinic receptor genes expressed in the murine libroblast (B82) cell line. J. Pharmacol. Exp. Ther., 284, 500-507.
23. LAZARENO, S. & BIRDSALL, N.J.M. (1995). Detection, quantitation, and verification of allosteric interactions of agents with labeled and unlabelcd ligands at G protein-coupled receptors: interactions of strychnine and acetylcholine at muscarinic receptors. Mol. Pharmacol., 48, 362-378.
24. LEE, N.H. & EL-FAKAHANY, E.E. (1991). Allosteric antagonists of the muscarinic acetylcholine receptor. Biochem. Pharmacol., 42, 199-205.
25. MILLER, J.H., AAGAARD, P.J., GIBSON, V.A. & MCKINNEY, M. (1992). Binding and functional selectivity of himbacine for cloned and neuronal muscarinic receptors. J. Pharmacol. Exp. Ther., 263, 663-667.
26. MOLENAAR, P. & POLAK, R.L. (1980). Inhibition of acetylcholine release by activation of acetylcholine receptors. Progr. Pharmacol., 3/4, 39-44.
27. MUSÍLKOVÁ, J. & TUČEK, S. (1995). Positive allosteric action of alcuronium on solubilized cardiac muscarinic receptors. Neurochem. Int., 27, 337-343.
28. 4 ligand muscarinic toxin 3 (MT3). Br. J. Pharmacol., 118, 283-288.
29. ONALI, P., AASEN, A.J. & OLIANAS, M.C. (1994). Antagonism by (R)-and (S)-trihexyphenidyl of muscarinic stimulation of adenylyl cyclase in rat olfactory bulb and inhibition in striatum and heart. Br. J. Pharmacol., 113, 775-780.
30. PROŠKA, J. & TUČEK, S. (1994). Mechanisms of steric and cooperative actions of alcuronium on cardiac muscarinic acetylcholine receptors. Mol. Pharmacol., 45, 709-717.
31. PROŠKA, J. & TUČEK, S. (1995). Competition between positive and negative allosteric effectors on muscarinic receptors. Mol. Pharmacol., 48, 696-702.
32. PURKERSON, S.L. & POTTER, L.T. (1998). Use of antimuscarinic toxins to facilitate studies of striatal m4 muscarinic receptors. J. Pharmacol. Exp. Ther., 284, 707-713.
33. RICHARDSON, I.W. & SZERB, J.C. (1974). The release of labelled acetylcholine and choline from cerebral cortical slices stimulated electrically. Br. J. Pharmacol., 52, 499-507.
34. STOCKTON, J.M., BIRDSALL, N.J.M., BURGEN, A.S.V. & HULME, E.C. (1983). Modification of the binding properties of muscarinic receptors by gallamine. Mol. Pharmacol., 23, 551-557.
35. TICE, M.A.B., HASHEMI, T., TAYLOR, L.A. & McQUADE, R.D. (1996). Distribution of muscarinic receptor subtypes in rat brain from postnatal to old age. Der. Brain Res., 92, 70-76.
36. TUČEK, S., MUSÍLKOVÁ, J., NEDOMA, J., PROŠKA, J., SHELKOVNIKOV, S. & VORLIČEK, J. (1990). Positive cooperativity in the binding of alcuronium and N-methylscopolamine to muscarinic acetylcholine receptors. Mol. Pharmacol., 38, 674-680.
37. TUČEK, S. & PROŠKA, J. (1995). Allosteric modulation of muscarinic acetylcholine receptors. Trends Pharmacol. Sci., 16, 205-212.
38. VANNUCCHI, M.G. & PEPEU, G. (1995). Muscarinic receptor modulation of acetylcholine release from rat cerebral cortex and hippocampus. Neurosci. Lett., 90, 53-56.
39. WEI, J., WALTON, E.A., MILICI, A. & BUCCAFUSCO, J.J. (1994). m1 m5 muscarinic receptor distribution in rat CNS by RT-PCR and HPLC. J. Neurochem., 63, 815-821.
40. WESS, J. (ed.) (1995). Molecular Mechanisms of Muscarinic Acetylcholine Receptor Function. Austin: R.G Landes Company, pp. 1-272.
41. 2+ currents in rat neostriatal cholinergic interneurons through a fast, membrane-delimited, G-protein pathway. J. Neurosci., 16, 2592-2604.
42. YASUDA, R.P. CIESLA, W., FLORES, L.R., WALL, S.J., LI, M., SATKUS, S.A., WEISSTEIN, J.S., SPAGNOLA, B.V. & WOLFE, B.B. (1993). Development of antisera for m4 and m5 muscarinic cholinergic receptors: distribution of m4 and m5 receptors in rat. Mol. Pharmacol., 43, 149-157.