Identification of a [3H]ligand for the common allosteric site of muscarinic acetylcholine M2 receptors

Molecular Pharmacology

Volumn 54, Issue 1, 1998, Pages 139-145

  Tränkle, Christian ^a   Mies Klomfass, Elisabeth ^a   Cid, Mario H Botero ^a   Holzgrabe, Ulrike ^a   Mohr, Klaus ^a  

^a UNIVERSITY OF BONN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

1,6 HEXAMETHYLENEBIS[DIMETHYL(3 PHTHALIMIDOPROPYL)AMMONIUM BROMIDE]; ALCURONIUM; METHYLSCOPOLAMINE; MUSCARINIC M2 RECEPTOR; MUSCARINIC M2 RECEPTOR AGONIST; N,N' BIS[3 (1,3 DIHYDRO 1,3 DIOXO 4 METHYL 2H ISOINDOL 2 YL)PROPYL] N,N,N',N' TETRAMETHYL 1,6 HEXANEDIAMINIUM DIIODIDE; OBIDOXIME; UNCLASSIFIED DRUG; CHOLINERGIC RECEPTOR BLOCKING AGENT; CHOLINESTERASE REACTIVATOR; DIMETHYL W84; DIMETHYL-W84; LIGAND; MUSCARINIC RECEPTOR; PHTHALIMIDE DERIVATIVE; RADIOPHARMACEUTICAL AGENT;

ANIMAL TISSUE; ARTICLE; BINDING SITE; CONTROLLED STUDY; DISSOCIATION CONSTANT; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; HEART; ISOTOPE LABELING; NONHUMAN; PRIORITY JOURNAL; RECEPTOR OCCUPANCY; SWINE; ANIMAL; CHEMISTRY; COMPARATIVE STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG INTERACTION; HEART MUSCLE; METABOLISM; SYNTHESIS;

ALLOSTERIC SITE; ANIMALS; CHOLINESTERASE REACTIVATORS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; HEART; LIGANDS; MYOCARDIUM; N-METHYLSCOPOLAMINE; OBIDOXIME CHLORIDE; PARASYMPATHOLYTICS; PHTHALIMIDES; RADIOPHARMACEUTICALS; RECEPTOR, MUSCARINIC M2; RECEPTORS, MUSCARINIC; SWINE;

EID: 0031595749     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.54.1.139     Document Type: Article

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