Adhesion-dependent control of Akt/protein kinase B occurs at multiple levels

Journal of Cellular Physiology

Volumn 196, Issue 1, 2003, Pages 98-104

  Le Gall, Maude ^a,b   Chambard, Jean Claude ^a   Grall, Dominique ^a   Van Obberghen Schilling, Ellen ^a  

^a CENTRE ANTOINE LACASSAGNE   (France)

^b Fred Hutchinson Cancer Research Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN KINASE B;

ANCHORAGE INDEPENDENT GROWTH; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL ADHESION; CELL DEATH; CELL SURVIVAL; CHINESE HAMSTER; CONTROL SYSTEM; ENZYME ACTIVATION; EXTRACELLULAR MATRIX; LUNG FIBROBLAST; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

ANIMALS; CASPASES; CELL ADHESION; CELL LINE; CRICETINAE; DOWN-REGULATION; FIBROBLASTS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RNA, MESSENGER;

EID: 0038622939     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.10276     Document Type: Article

References (42)

1. Alessi DR, Cohen P. 1998. Mechanism of activation and function of protein kinase B. Curr Opin Genet Dev 8:55-62.
2. Andjelkovic M, Alessi DR, Meier R, Fernandez A, Lamb NJ, Frech M, Cron P, Cohen P, Lucocq JM, Hemmings BA. 1997. Role of translocation in the activation and function of protein kinase B. J Biol Chem 272:31515-31524.
3. Assoian RK. 1997. Anchorage-dependent cell cycle progression. J Cell Biol 136:1-4.
4. Bachelder RE, Ribick MJ, Marchetti A, Falcioni R, Soddu S, Davis KR, Mercurio AM. 1999. p53 inhibits alpha 6 beta 4 integrin survival signaling by promoting the caspase 3-dependent cleavage of AKT/PKB. J Cell Biol 147:1063-1072.
5. Bachelder RE, Wendt MA, Fujita N, Tsuruo T, Mercurio AM. 2001. The cleavage of Akt/protein kinase B by death receptor signaling is an important event in detachment-induced apoptosis. J Biol Chem 276:34702-34707.
6. Bellacosa A, Testa JR, Staal SP, Tsichlis PN. 1991. A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region. Science 254:274-277.
7. Biggs WH, Meisenhelder J III, Hunter T, Cavenee WK, Arden KC. 1999. Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1. Proc Natl Acad Sci USA 96:7421-7426.
8. Brunet A, Bonni A, Zigmond MJ, Lin MZ, Juo P, Hu LS, Anderson MJ, Arden KC, Blenis J, Greenberg ME. 1999. Akt promotes cell survival by phosphorylating and inhibiting a forkhead transcription factor. Cell 96:857-868.
9. Burgering BM, Coffer PJ. 1995. Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature 376:599-602.
10. Cardone MH, Roy N, Stennicke HR, Salvesen GS, Franke TF, Stanbridge E, Frisch S, Reed JC. 1998. Regulation of cell death protease caspase-9 by phosphorylation. Science 282:1318-1321.
11. Coffer PJ, Woodgett JR. 1991. Molecular cloning and characterisation of a novel putative protein-serine kinase related to the cAMP-dependent and protein kinase C families. Eur J Biochem 201:475-481.
12. Datta SR, Dudek H, Tao X, Masters S, Fu H, Gotoh Y, Greenberg ME. 1997. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 91:231-241.
13. Datta SR, Brunet A, Greenberg ME. 1999. Cellular survival: A play in three Akts. Genes Dev 13:2905-2927.
14. del Peso L, Gonzalez GM, Page C, Herrera R, Nunez G. 1997. Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt. Science 278:687-689.
15. Dimmeler S, Fleming I, Fisslthaler B, Hermann C, Busse R, Zeiher AM. 1999. Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation. Nature 399:601-605.
16. Francois F, Grimes ML. 1999. Phosphorylation-dependent Akt cleavage in neural cell in vitro reconstitution of apoptosis. J Neurochem 73:1773-1776.
17. Frisch SM, Ruoslahti E. 1997. Integrins and anoikis. Curr Opin Cell Biol 9:701-706.
18. Frisch SM, Screaton RA. 2001. Anoikis mechanisms. Curr Opin Cell Biol 13:555-562.
19. Frisch SM, Vuori K, Ruoslahti E, Chan HP. 1996. Control of adhesion-dependent cell survival by focal adhesion kinase. J Cell Biol 134:793-799.
20. Fujio Y, Walsh K. 1999. Akt mediates cytoprotection of endothelial cells by vascular endothelial growth factor in an anchorage-dependent manner. J Biol Chem 274:16349-16354.
21. Fulton D, Gratton JP, McCabe TJ, Fontana J, Fujio Y, Walsh K, Franke TF, Papapetropoulos A, Sessa WC. 1999. Regulation of endothelium-derived nitric oxide production by the protein kinase Akt. Nature 399:597-601.
22. Geiger B, Bershadsky A, Pankov R, Yamada KM. 2001. Transmembrane crosstalk between the extracellular matrix-cytoskeleton crosstalk. Nat Rev Mol Cell Biol 2:793-805.
23. Giancotti FG, Ruoslahti E. 1999. Integrin signaling. Science 285:1028-1032.
24. Jones PF, Jakubowicz T, Pitossi FJ, Maurer F, Hemmings BA. 1991. Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily. Proc Natl Acad Sci USA 88:4171-4175.
25. Kandel ES, Hay N. 1999. The regulation and activities of the multi-functional serine/threonine kinase Akt/PKB. Exp Cell Res 253:210-229.
26. Khwaja A, Rodriguez VP, Wennstrom S, Warne PH, Downward J. 1997. Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway. EMBO J 16:2783-2793.
27. King WG, Mattaliano MD, Chan TO, Tsichlis PN, Brugge JS. 1997. Phosphatidylinositol 3-kinase is required for integrin-stimulated AKT and Raf-1/mitogen-activated protein kinase pathway activation. Mol Cell Biol 17:4406-4418.
28. Kops GJ, de Ruiter ND, De Vries-Smits AM, Powell DR, Bos JL, Burgering BM. 1999. Direct control of the forkhead transcription factor AFX by protein kinase B. Nature 398:630-634.
29. Le Gall M, Grall D, Chambard JC, Pouysségur J, Van Obberghen-Schilling E. 1998. An anchorage-dependent signal distinct from p42/44 MAP kinase activation is required for cell cycle progression. Oncogene 17:1271-1277.
30. Le Gall M, Chambard JC, Breittmayer JP, Grall D, Pouyssegur J, Van Obberghen-Schilling E. 2000. The p42/p44 MAP kinase pathway prevents apoptosis induced by anchorage and serum removal. Mol Biol Cell 11:1103-1112.
31. Lenormand P, McMahon M, Pouysségur J. 1996. Oncogenic Raf-1 activates p70 S6 kinase via a mitogen-activated protein kinase-independent pathway. J Biol Chem 271:15762-15768.
32. Meloche S, Pages G, Pouyssegur J. 1992. Functional expression and growth factor activation of an epitope-tagged p44 mitogen-activated protein kinase, p44mapk.
33. Nakae J, Park BC, Accili D. 1999. Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a Wortmannin-sensitive pathway. J Biol Chem 274:15982-15985.
34. Piechaczyk M, Blanchard JM, Marty L, Dani C, Panabieres F, El Sabouty S, Fort P, Jeanteur P. 1984. Post-transcriptional regulation of glyceraldehyde-3-phosphate-dehydrogenase gene expression in rat tissues. Nucleic Acids Res 12:6951-6963.
35. Rena G, Guo S, Cichy SC, Unterman TG, Cohen P. 1999. Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B. J Biol Chem 274:17179-17183.
36. Rokudai S, Fujita N, Hashimoto Y, Tsuruo T. 2000. Cleavage and inactivation of antiapoptotic Akt/PKB by caspases during apoptosis. J Cell Physiol 182:290-296.
37. Schwartz MA. 2001. Integrin signaling revisited. Trends Cell Biol 11:466-470.
38. Schwartz MA, Assoian RK. 2001. Integrins and cell proliferation: Regulation of cyclin-dependent kinases via cytoplasmic signaling pathways. J Cell Sci 114:2553-2560.
39. Vincent S, Marty L, Fort P. 1993. S26 ribosomal protein RNA: An invariant control for gene regulation experiments in eucaryotic cells and tissues. Nucleic Acids Res 21:1498.
40. Widmann C, Gibson S, Johnson GL. 1998. Caspase-dependent cleavage of signaling proteins during apoptosis. A turn-off mechanism for anti-apoptotic signals. J Biol Chem 273:7141-7147.
41. Xu J, Liu D, Songyang Z. 2002. The role of Asp462 in regulating Akt activity. J Biol Chem 17:17.
42. Yamada KM, Even-Ram S. 2002. Integrin regulation of growth factor receptors. Nat Cell Biol 4:E75-E76.