-
1
-
-
0032190081
-
The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM
-
Sayos J, et al. The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM. Nature 1998;395:462-469.
-
(1998)
Nature
, vol.395
, pp. 462-469
-
-
Sayos, J.1
-
2
-
-
13144278345
-
Inactivating mutations in an SH2 domain-encoding gene in X-linked lymphoproliferative syndrome
-
Nichols KE, et al. Inactivating mutations in an SH2 domain-encoding gene in X-linked lymphoproliferative syndrome. Proc Natl Acad Sci USA 1998;95:13765-13770.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 13765-13770
-
-
Nichols, K.E.1
-
3
-
-
17344372694
-
Host response to EBV infection in X-linked lymphoproliferative disease results from mutations in an SH2-domain encoding gene
-
Coffey AJ, et al. Host response to EBV infection in X-linked lymphoproliferative disease results from mutations in an SH2-domain encoding gene. Nat Genet 1998;20:129-135.
-
(1998)
Nat Genet
, vol.20
, pp. 129-135
-
-
Coffey, A.J.1
-
4
-
-
0035063939
-
X-linked lymphoproliferative disease: A progressive immunodeficiency
-
Morra M, et al. X-linked lymphoproliferative disease: a progressive immunodeficiency. Annu Rev Immunol 2001;19:657-682.
-
(2001)
Annu Rev Immunol
, vol.19
, pp. 657-682
-
-
Morra, M.1
-
5
-
-
0037133403
-
The SAP family: A new class of adaptor-like molecules that regulates immune cell functions
-
Veillette A. The SAP family: a new class of adaptor-like molecules that regulates immune cell functions. Sci STKE 2002:E8.
-
(2002)
Sci STKE
-
-
Veillette, A.1
-
6
-
-
0016772968
-
X-linked recessive progressive combined variable immunodeficiency (Duncan's disease)
-
Purtilo DT, Cassel CK, Yang JP, Harper R. X-linked recessive progressive combined variable immunodeficiency (Duncan's disease). Lancet 1975;1:935-940.
-
(1975)
Lancet
, vol.1
, pp. 935-940
-
-
Purtilo, D.T.1
Cassel, C.K.2
Yang, J.P.3
Harper, R.4
-
7
-
-
0029161779
-
X-linked lymphoproliferative disease: Twenty-five years after the discovery
-
Seemayer TA, et al. X-linked lymphoproliferative disease: twenty-five years after the discovery. Pediatr Res 1995;38:471-478.
-
(1995)
Pediatr Res
, vol.38
, pp. 471-478
-
-
Seemayer, T.A.1
-
8
-
-
0035469882
-
Alterations of the X-linked lymphoproliferative disease gene SH2D1A in common variable immunodeficiency syndrome
-
Morra M, et al. Alterations of the X-linked lymphoproliferative disease gene SH2D1A in common variable immunodeficiency syndrome. Blood 2001;98:1321-1325.
-
(2001)
Blood
, vol.98
, pp. 1321-1325
-
-
Morra, M.1
-
9
-
-
0035350808
-
SAP controls T cell responses to virus and terminal differentiation of Th2 cells
-
Wu C, et al. SAP controls T cell responses to virus and terminal differentiation of Th2 cells. Nat Immunol 2001;2:410-414.
-
(2001)
Nat Immunol
, vol.2
, pp. 410-414
-
-
Wu, C.1
-
10
-
-
0035912823
-
Altered lymphocyte responses and cytokine production in mice deficient in the X-linked lymphoproliferative disease gene SH2D1A/DSHP/SAP
-
Czar MJ, et al. Altered lymphocyte responses and cytokine production in mice deficient in the X-linked lymphoproliferative disease gene SH2D1A/DSHP/SAP. Proc Natl Acad Sci USA 2001;98:7449-7454.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 7449-7454
-
-
Czar, M.J.1
-
11
-
-
0022460495
-
Defective natural killing activity but retention of lymphocyte-mediated antibody-dependent cellular cytotoxicity in patients with the X-linked lymphoproliferative syndrome
-
Argov S, Johnson DR, Collins M, Koren HS, Lipscomb H, Purtilo DT. Defective natural killing activity but retention of lymphocyte-mediated antibody-dependent cellular cytotoxicity in patients with the X-linked lymphoproliferative syndrome. Cell Immunol 1986;100:1-9.
-
(1986)
Cell Immunol
, vol.100
, pp. 1-9
-
-
Argov, S.1
Johnson, D.R.2
Collins, M.3
Koren, H.S.4
Lipscomb, H.5
Purtilo, D.T.6
-
12
-
-
0020385108
-
Cell-mediated immunity to Epstein-Barr virus (EBV) and natural killer (NK)-cell activity in the X-linked lymphoproliferative syndrome
-
Harada S, Bechtold T, Seeley JK, Purtilo DT. Cell-mediated immunity to Epstein-Barr virus (EBV) and natural killer (NK)-cell activity in the X-linked lymphoproliferative syndrome. Int J Cancer 1982;30:739-744.
-
(1982)
Int J Cancer
, vol.30
, pp. 739-744
-
-
Harada, S.1
Bechtold, T.2
Seeley, J.K.3
Purtilo, D.T.4
-
13
-
-
0019255923
-
Deficient natural killer cell activity in X-linked lymphoproliferative syndrome
-
Sullivan JL, Byron KS, Brewster FE, Purtilo DT. Deficient natural killer cell activity in X-linked lymphoproliferative syndrome. Science 1980;210:543-545.
-
(1980)
Science
, vol.210
, pp. 543-545
-
-
Sullivan, J.L.1
Byron, K.S.2
Brewster, F.E.3
Purtilo, D.T.4
-
14
-
-
0035479955
-
The role of cytotoxicity in lymphocyte homeostasis
-
de Saint Basile G, Fischer A. The role of cytotoxicity in lymphocyte homeostasis. Curr Opin Immunol 2001;13:549-554.
-
(2001)
Curr Opin Immunol
, vol.13
, pp. 549-554
-
-
De Saint Basile, G.1
Fischer, A.2
-
15
-
-
0030446259
-
EAT-2 is a novel SH2 domain containing protein that is upregulated by Ewing's sarcoma EWS/FLI1 fusion gene
-
Thompson AD, et al. EAT-2 is a novel SH2 domain containing protein that is upregulated by Ewing's sarcoma EWS/FLI1 fusion gene. Oncogene 1996;13:2649-2658.
-
(1996)
Oncogene
, vol.13
, pp. 2649-2658
-
-
Thompson, A.D.1
-
16
-
-
17944380327
-
Structural basis for the interaction of the free SH2 domain EAT-2 with SLAM receptors in hematopoietic cells
-
Morra M, et al. Structural basis for the interaction of the free SH2 domain EAT-2 with SLAM receptors in hematopoietic cells. EMBO J 2001;20:5840-5852.
-
(2001)
EMBO J
, vol.20
, pp. 5840-5852
-
-
Morra, M.1
-
17
-
-
0035965317
-
Characterization of SH2D1A missense mutations identified in X-linked lymphoproliferative disease patients
-
Morra M, et al. Characterization of SH2D1A missense mutations identified in X-linked lymphoproliferative disease patients. J Biol Chem 2001;276:36809-36816.
-
(2001)
J Biol Chem
, vol.276
, pp. 36809-36816
-
-
Morra, M.1
-
18
-
-
0034331249
-
Correlation of mutations of the SH2D1A gene and Epstein-Barr virus infection with clinical phenotype and outcome in X-linked lymphoproliferative disease
-
Sumegi J, et al. Correlation of mutations of the SH2D1A gene and Epstein-Barr virus infection with clinical phenotype and outcome in X-linked lymphoproliferative disease. Blood 2000;96:3118-3125.
-
(2000)
Blood
, vol.96
, pp. 3118-3125
-
-
Sumegi, J.1
-
19
-
-
0032756539
-
Epstein-Barr virus-negative boys with non-Hodgkin lymphoma are mutated in the SH2D1A gene, as are patients with X-linked lymphoproliferative disease (XLP)
-
Brandan O, et al. Epstein-Barr virus-negative boys with non-Hodgkin lymphoma are mutated in the SH2D1A gene, as are patients with X-linked lymphoproliferative disease (XLP). Hum Mol Genet 1999;8:2407-2413.
-
(1999)
Hum Mol Genet
, vol.8
, pp. 2407-2413
-
-
Brandan, O.1
-
20
-
-
0033212986
-
Crystal structures of the XLP protein SAP reveal a class of SH2 domains with extended, phosphotyrosine-independent sequence recognition
-
Poy F, et al. Crystal structures of the XLP protein SAP reveal a class of SH2 domains with extended, phosphotyrosine-independent sequence recognition. Mol Cell 1999;4:555-561.
-
(1999)
Mol Cell
, vol.4
, pp. 555-561
-
-
Poy, F.1
-
21
-
-
18244395893
-
A 'three-pronged' binding mechanism for the SAP/SH2D1A SH2 domain: Structural basis and relevance to the XLP syndrome
-
Hwang PM, et al. A 'three-pronged' binding mechanism for the SAP/SH2D1A SH2 domain: structural basis and relevance to the XLP syndrome. EMBO J 2002;21:314-323.
-
(2002)
EMBO J
, vol.21
, pp. 314-323
-
-
Hwang, P.M.1
-
22
-
-
0033518296
-
Novel mode of ligand binding by the SH2 domain of the human XLP disease gene product SAP/SH2D1A
-
Li SC, et al. Novel mode of ligand binding by the SH2 domain of the human XLP disease gene product SAP/SH2D1A. Curr Biol 1999;9:1355-1362.
-
(1999)
Curr Biol
, vol.9
, pp. 1355-1362
-
-
Li, S.C.1
-
23
-
-
0034889004
-
Regulation of SLAM-mediated signal transduction by SAP, the X-linked lymphoproliferative gene product
-
Latour S, Gish G, Helgason CD, Humphries RK, Pawson T, Veillette A. Regulation of SLAM-mediated signal transduction by SAP, the X-linked lymphoproliferative gene product. Nat Immunol 2001;2:681-690.
-
(2001)
Nat Immunol
, vol.2
, pp. 681-690
-
-
Latour, S.1
Gish, G.2
Helgason, C.D.3
Humphries, R.K.4
Pawson, T.5
Veillette, A.6
-
24
-
-
0029043647
-
A novel receptor involved in T-cell activation
-
Cocks BG, Chang CC, Carballido JM, Yssel H, de Vries JE, Aversa G. A novel receptor involved in T-cell activation. Nature 1995;376:260-263.
-
(1995)
Nature
, vol.376
, pp. 260-263
-
-
Cocks, B.G.1
Chang, C.C.2
Carballido, J.M.3
Yssel, H.4
De Vries, J.E.5
Aversa, G.6
-
25
-
-
0027383871
-
Cloning and characterization of the 2B4 gene encoding a molecule associated with non-MHC-restricted killing mediated by activated natural killer cells and T cells
-
Mathew PA, et al. Cloning and characterization of the 2B4 gene encoding a molecule associated with non-MHC-restricted killing mediated by activated natural killer cells and T cells. J Immunol 1993;151:5328-5237.
-
(1993)
J Immunol
, vol.151
, pp. 5328-5237
-
-
Mathew, P.A.1
-
26
-
-
0035383767
-
Molecular characterization and expression of a novel human leukocyte cell-surface marker homologous to mouse Ly-9
-
de la Fuente MA, et al. Molecular characterization and expression of a novel human leukocyte cell-surface marker homologous to mouse Ly-9. Blood 2001;97:3513-3520.
-
(2001)
Blood
, vol.97
, pp. 3513-3520
-
-
De La Fuente, M.A.1
-
27
-
-
0030817218
-
CD84 leukocyte antigen is a new member of the Ig superfamily
-
de la Fuente MA, Pizcueta P, Nadal M, Bosch J, Engel P. CD84 leukocyte antigen is a new member of the Ig superfamily. Blood 1997;90:2398-2405.
-
(1997)
Blood
, vol.90
, pp. 2398-2405
-
-
De La Fuente, M.A.1
Pizcueta, P.2
Nadal, M.3
Bosch, J.4
Engel, P.5
-
28
-
-
0035817326
-
NTB-A, a novel SH2D1A-associated surface molecule contributing to the inability of natural killer cells to kill Epstein-Barr virus-infected B cells in X-linked lymphoproliferative disease
-
Bottino C, et al. NTB-A, a novel SH2D1A-associated surface molecule contributing to the inability of natural killer cells to kill Epstein-Barr virus-infected B cells in X-linked lymphoproliferative disease. J Exp Med 2001;194:235-246.
-
(2001)
J Exp Med
, vol.194
, pp. 235-246
-
-
Bottino, C.1
-
29
-
-
0035890037
-
Cutting edge: Activation of NK cell-mediated cytotoxicity by a SAP-independent receptor of the CD2 family
-
Bouchon A, Cella M, Grierson HL, Cohen JI, Colonna M. Cutting edge: activation of NK cell-mediated cytotoxicity by a SAP-independent receptor of the CD2 family. J Immunol 2001;167:5517-5521.
-
(2001)
J Immunol
, vol.167
, pp. 5517-5521
-
-
Bouchon, A.1
Cella, M.2
Grierson, H.L.3
Cohen, J.I.4
Colonna, M.5
-
30
-
-
0034109091
-
The CD2-subset of the Ig superfamily of cell surface molecules: Receptor-ligand pairs expressed by NK cells and other immune cells
-
Tangye SG, Phillips JH, Lanier LL. The CD2-subset of the Ig superfamily of cell surface molecules: receptor-ligand pairs expressed by NK cells and other immune cells. Semin Immunol 2000;12:149-157.
-
(2000)
Semin Immunol
, vol.12
, pp. 149-157
-
-
Tangye, S.G.1
Phillips, J.H.2
Lanier, L.L.3
-
31
-
-
0034618065
-
X-linked lymphoproliferative disease. 2B4 molecules displaying inhibitory rather than activating function are responsible for the inability of natural killer cells to kill Epstein-Barr virus-infected cells
-
Parolini S, et al. X-linked lymphoproliferative disease. 2B4 molecules displaying inhibitory rather than activating function are responsible for the inability of natural killer cells to kill Epstein-Barr virus-infected cells. J Exp Med 2000;192:337-346.
-
(2000)
J Exp Med
, vol.192
, pp. 337-346
-
-
Parolini, S.1
-
32
-
-
0034664724
-
Functional requirement for SAP in 2B4-mediated activation of human natural killer cells as revealed by the X-linked lymphoproliferative syndrome
-
Tangye SG, Phillips JH, Lanier LL, Nichols KE. Functional requirement for SAP in 2B4-mediated activation of human natural killer cells as revealed by the X-linked lymphoproliferative syndrome. J Immunol 2000;165:2932-2936.
-
(2000)
J Immunol
, vol.165
, pp. 2932-2936
-
-
Tangye, S.G.1
Phillips, J.H.2
Lanier, L.L.3
Nichols, K.E.4
-
33
-
-
0033564638
-
Cutting edge: Human 2B4, an activating NK cell receptor, recruits the protein tyrosine phosphatase SHP-2 and the adaptor signaling protein SAP
-
Tangye SG, Lazetic S, Woollatt E, Sutherland GR, Lanier LL, Phillips JH. Cutting edge: human 2B4, an activating NK cell receptor, recruits the protein tyrosine phosphatase SHP-2 and the adaptor signaling protein SAP. J Immunol 1999;162:6981-6985.
-
(1999)
J Immunol
, vol.162
, pp. 6981-6985
-
-
Tangye, S.G.1
Lazetic, S.2
Woollatt, E.3
Sutherland, G.R.4
Lanier, L.L.5
Phillips, J.H.6
-
34
-
-
0035878004
-
Cell surface receptors Ly-9 and CD84 recruit the X-linked lymphoproliferative disease gene product SAP
-
Sayos J, et al. Cell surface receptors Ly-9 and CD84 recruit the X-linked lymphoproliferative disease gene product SAP. Blood 2001;97:3867-3874.
-
(2001)
Blood
, vol.97
, pp. 3867-3874
-
-
Sayos, J.1
-
35
-
-
0035102841
-
Protein tyrosine phosphatase CD148-mediated inhibition of T-cell receptor signal transduction is associated with reduced LAT and phospholipase Cgamma1 phosphorylation
-
Baker JE, Majeti R, Tangye SG, Weiss A. Protein tyrosine phosphatase CD148-mediated inhibition of T-cell receptor signal transduction is associated with reduced LAT and phospholipase Cgamma1 phosphorylation. Mol Cell Biol 2001;21:2393-2403.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 2393-2403
-
-
Baker, J.E.1
Majeti, R.2
Tangye, S.G.3
Weiss, A.4
-
36
-
-
18344369877
-
Identification and characterization of SF2000 and SF2001, two new members of the immune receptor SLAM/CD2 family
-
Fraser CC, et al. Identification and characterization of SF2000 and SF2001, two new members of the immune receptor SLAM/CD2 family. Immunogenetics 2002;53:843-850.
-
(2002)
Immunogenetics
, vol.53
, pp. 843-850
-
-
Fraser, C.C.1
-
37
-
-
0035339915
-
Cloning, expression, and function of BLAME, a novel member of the CD2 family
-
Kingsbury GA, et al. Cloning, expression, and function of BLAME, a novel member of the CD2 family. J Immunol 2001;166:5675-5680.
-
(2001)
J Immunol
, vol.166
, pp. 5675-5680
-
-
Kingsbury, G.A.1
-
38
-
-
0034765175
-
CD2F-10: A new member of the CD2 subset of the immunoglobulin superfamily
-
Fennelly JA, Tiwari B, Davis SJ, Evans EJ. CD2F-10: a new member of the CD2 subset of the immunoglobulin superfamily. Immunogenetics 2001;53:599-602.
-
(2001)
Immunogenetics
, vol.53
, pp. 599-602
-
-
Fennelly, J.A.1
Tiwari, B.2
Davis, S.J.3
Evans, E.J.4
-
39
-
-
0030910358
-
Soluble and membrane-bound forms of signaling lymphocytic activation molecule (SLAM) induce proliferation and Ig synthesis by activated human B lymphocytes
-
Punnonen J, et al. Soluble and membrane-bound forms of signaling lymphocytic activation molecule (SLAM) induce proliferation and Ig synthesis by activated human B lymphocytes. J Exp Med 1997;185:993-1004.
-
(1997)
J Exp Med
, vol.185
, pp. 993-1004
-
-
Punnonen, J.1
-
40
-
-
0034623152
-
Signaling lymphocytic activation molecule (CDw 150) is homophilic but self-associates with very low affinity
-
Mavaddat N, et al. Signaling lymphocytic activation molecule (CDw 150) is homophilic but self-associates with very low affinity. J Biol Chem 2000;275:28100-28109.
-
(2000)
J Biol Chem
, vol.275
, pp. 28100-28109
-
-
Mavaddat, N.1
-
41
-
-
0035478348
-
CD84 functions as a homophilic adhesion molecule and enhances IFN-gamma secretion: Adhesion is mediated by Ig-like domain 1
-
Martin M, et al. CD84 functions as a homophilic adhesion molecule and enhances IFN-gamma secretion: adhesion is mediated by Ig-like domain 1. J Immunol 2001;167:3668-3676.
-
(2001)
J Immunol
, vol.167
, pp. 3668-3676
-
-
Martin, M.1
-
42
-
-
0037105245
-
CS1, a novel member of the CD2 family, is homophilic and regulates NK cell function
-
Kumaresan P, Lai W, Chuang S, Bennett M, Mathew P. CS1, a novel member of the CD2 family, is homophilic and regulates NK cell function. Mol Immunol 2002;39:1.
-
(2002)
Mol Immunol
, vol.39
, pp. 1
-
-
Kumaresan, P.1
Lai, W.2
Chuang, S.3
Bennett, M.4
Mathew, P.5
-
43
-
-
0032406389
-
Identification of the 2B4 molecule as a counter-receptor for CD48
-
Latchman Y, McKay PF, Reiser H. Identification of the 2B4 molecule as a counter-receptor for CD48. J Immunol 1998;161:5809-5812.
-
(1998)
J Immunol
, vol.161
, pp. 5809-5812
-
-
Latchman, Y.1
McKay, P.F.2
Reiser, H.3
-
44
-
-
0035915993
-
CDw150 (SLAM) is a receptor for a lymphotropic strain of measles virus and may account for the immunosuppressive properties of this virus
-
Hsu EC, Iorio C, Sarangi F, Khine AA, Richardson CD. CDw150 (SLAM) is a receptor for a lymphotropic strain of measles virus and may account for the immunosuppressive properties of this virus. Virology 2001;279:9-21.
-
(2001)
Virology
, vol.279
, pp. 9-21
-
-
Hsu, E.C.1
Iorio, C.2
Sarangi, F.3
Khine, A.A.4
Richardson, C.D.5
-
45
-
-
0034710650
-
SLAM (CDw150) is a cellular receptor for measles virus
-
Tatsuo H, Ono N, Tanaka K, Yanagi Y. SLAM (CDw150) is a cellular receptor for measles virus. Nature 2000;406:893-897.
-
(2000)
Nature
, vol.406
, pp. 893-897
-
-
Tatsuo, H.1
Ono, N.2
Tanaka, K.3
Yanagi, Y.4
-
46
-
-
0033729573
-
Patients with X-linked lymphoproliferative disease have a defect in 2B4 receptor-mediated NK cell cytotoxicity
-
Nakajima H, et al. Patients with X-linked lymphoproliferative disease have a defect in 2B4 receptor-mediated NK cell cytotoxicity. Eur J Immunol 2000;30:3309-3318.
-
(2000)
Eur J Immunol
, vol.30
, pp. 3309-3318
-
-
Nakajima, H.1
-
47
-
-
0038443147
-
Binding of SAP SH2 domain to FynT SH3 domain reveal a novel mechanism of receptor signalling in immune regulation
-
in press
-
Latour S, et al. Binding of SAP SH2 domain to FynT SH3 domain reveal a novel mechanism of receptor signalling in immune regulation. Nat Cell Biol (in press).
-
Nat Cell Biol
-
-
Latour, S.1
-
48
-
-
0028973001
-
Comparison of p56lck and p59fyn protein expression in thymocyte subsets, peripheral T cells, NK cells, and lymphoid cell lines
-
Olszowy, MW, Leuchtmann, PL, Veillette, A, Shaw, AS. Comparison of p56lck and p59fyn protein expression in thymocyte subsets, peripheral T cells, NK cells, and lymphoid cell lines. J Immunol 1995;155:4236-4240.
-
(1995)
J Immunol
, vol.155
, pp. 4236-4240
-
-
Olszowy, M.W.1
Leuchtmann, P.L.2
Veillette, A.3
Shaw, A.S.4
-
49
-
-
0026669001
-
Defective T cell receptor signaling in mice lacking the thymic isoform of p59fyn
-
Appleby MW, Gross JA, Cooke MP, Levin SD, Qian X, Perlmutter RM. Defective T cell receptor signaling in mice lacking the thymic isoform of p59fyn. Cell 1992;70:751-763.
-
(1992)
Cell
, vol.70
, pp. 751-763
-
-
Appleby, M.W.1
Gross, J.A.2
Cooke, M.P.3
Levin, S.D.4
Qian, X.5
Perlmutter, R.M.6
-
50
-
-
0026612411
-
pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cells
-
Stein PL, Lee HM, Rich S, Soriano P. pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cells. Cell 1992;70:741-750.
-
(1992)
Cell
, vol.70
, pp. 741-750
-
-
Stein, P.L.1
Lee, H.M.2
Rich, S.3
Soriano, P.4
-
52
-
-
0028984841
-
Involvement of p59fynT in interleukin-5 receptor signaling
-
Appleby MW, et al. Involvement of p59fynT in interleukin-5 receptor signaling. J Exp Med 1995;182:811-820.
-
(1995)
J Exp Med
, vol.182
, pp. 811-820
-
-
Appleby, M.W.1
-
53
-
-
0032723181
-
The Src family tyrosine kinase Fyn regulates natural killer T cell development
-
Gadue P, Morton N, Stein PL. The Src family tyrosine kinase Fyn regulates natural killer T cell development. J Exp Med 1999;190:1189-1196.
-
(1999)
J Exp Med
, vol.190
, pp. 1189-1196
-
-
Gadue, P.1
Morton, N.2
Stein, P.L.3
-
54
-
-
0032853934
-
Cutting edge: NKT cell development is selectively impaired in Fyn- deficient mice
-
Eberl G, Lowin-Kropf B, MacDonald HR. Cutting edge: NKT cell development is selectively impaired in Fyn- deficient mice. J Immunol 1999;163:4091-4094.
-
(1999)
J Immunol
, vol.163
, pp. 4091-4094
-
-
Eberl, G.1
Lowin-Kropf, B.2
MacDonald, H.R.3
-
55
-
-
0036347746
-
Fyn kinase initiates complementary signals required for IgE-dependent mast cell degranulation
-
Parravicini V, et al. Fyn kinase initiates complementary signals required for IgE-dependent mast cell degranulation. Nat Immunol 2002;3:741-748.
-
(2002)
Nat Immunol
, vol.3
, pp. 741-748
-
-
Parravicini, V.1
-
56
-
-
0033485397
-
Molecular and functional characterization of mouse signaling lymphocytic activation molecule (SLAM): Differential expression and responsiveness in Th1 and Th2 cells
-
Castro AG, et al. Molecular and functional characterization of mouse signaling lymphocytic activation molecule (SLAM): differential expression and responsiveness in Th1 and Th2 cells. J Immunol 1999;163:5860-5870.
-
(1999)
J Immunol
, vol.163
, pp. 5860-5870
-
-
Castro, A.G.1
-
57
-
-
0035881677
-
Signaling lymphocytic activation molecule is expressed on mature CD83(+) dendritic cells and is up-regulated by IL-1beta
-
Kruse M, et al. Signaling lymphocytic activation molecule is expressed on mature CD83(+) dendritic cells and is up-regulated by IL-1beta. J Immunol 2001;167:1989-1995.
-
(2001)
J Immunol
, vol.167
, pp. 1989-1995
-
-
Kruse, M.1
-
58
-
-
0035885005
-
Signaling lymphocytic activation molecule is expressed on CD40 ligand-activated dendritic cells and directly augments production of inflammatory cytokines
-
Bleharski JR, Niazi KR, Sieling PA, Cheng G, Modlin RL. Signaling lymphocytic activation molecule is expressed on CD40 ligand-activated dendritic cells and directly augments production of inflammatory cytokines. J Immunol 2001;167:3174-3181.
-
(2001)
J Immunol
, vol.167
, pp. 3174-3181
-
-
Bleharski, J.R.1
Niazi, K.R.2
Sieling, P.A.3
Cheng, G.4
Modlin, R.L.5
-
59
-
-
0037108562
-
The role of SAP in murine CD150 (SLAM)-mediated T-cell proliferation and interferon gamma production
-
Howie D, et al. The role of SAP in murine CD150 (SLAM)-mediated T-cell proliferation and interferon gamma production. Blood 2002;100:2899-2907.
-
(2002)
Blood
, vol.100
, pp. 2899-2907
-
-
Howie, D.1
-
60
-
-
0031279959
-
Reversal of human allergic T helper 2 responses by engagement of signaling lymphocytic activation molecule
-
Carballido JM, et al. Reversal of human allergic T helper 2 responses by engagement of signaling lymphocytic activation molecule. J Immunol 1997;159:4316-4321.
-
(1997)
J Immunol
, vol.159
, pp. 4316-4321
-
-
Carballido, J.M.1
-
61
-
-
0031136953
-
Engagement of the signaling lymphocytic activation molecule (SLAM) on activated T cells results in IL-2-independent, cyclosporin A-sensitive T cell proliferation and IFN-gamma production
-
Aversa G, Chang CC, Carballido JM, Cocks BG, de Vries JE. Engagement of the signaling lymphocytic activation molecule (SLAM) on activated T cells results in IL-2-independent, cyclosporin A-sensitive T cell proliferation and IFN-gamma production. J Immunol 1997;158:4036-4044.
-
(1997)
J Immunol
, vol.158
, pp. 4036-4044
-
-
Aversa, G.1
Chang, C.C.2
Carballido, J.M.3
Cocks, B.G.4
De Vries, J.E.5
-
62
-
-
0033804532
-
Lipid phosphatases in the immune system
-
Krystal G. Lipid phosphatases in the immune system. Semin Immunol 2000;12:397-403.
-
(2000)
Semin Immunol
, vol.12
, pp. 397-403
-
-
Krystal, G.1
-
63
-
-
0034635562
-
Resting lymphocyte kinase (Rlk/Txk) targets lymphoid adaptor SLP-76 in the cooperative activation of interleukin-2 transcription in T-cells
-
Schneider H, Guerette B, Guntermann C, Rudd CE. Resting lymphocyte kinase (Rlk/Txk) targets lymphoid adaptor SLP-76 in the cooperative activation of interleukin-2 transcription in T-cells. J Biol Chem 2000;275:3835-3840.
-
(2000)
J Biol Chem
, vol.275
, pp. 3835-3840
-
-
Schneider, H.1
Guerette, B.2
Guntermann, C.3
Rudd, C.E.4
-
64
-
-
0033597440
-
Requirement for Tec kinases Rlk and Itk in T cell receptor signaling and immunity
-
Schaeffer EM, et al. Requirement for Tec kinases Rlk and Itk in T cell receptor signaling and immunity. Science 1999;284:638-641.
-
(1999)
Science
, vol.284
, pp. 638-641
-
-
Schaeffer, E.M.1
-
65
-
-
0028910356
-
Identification of Rlk, a novel protein tyrosine kinase with predominant expression in the T cell lineage
-
Hu Q, et al. Identification of Rlk, a novel protein tyrosine kinase with predominant expression in the T cell lineage. J Biol Chem 1995;270:1928-1934.
-
(1995)
J Biol Chem
, vol.270
, pp. 1928-1934
-
-
Hu, Q.1
-
66
-
-
0035194916
-
Mutation of Tec family kinases alters T helper cell differentiation
-
Schaeffer EM, et al. Mutation of Tec family kinases alters T helper cell differentiation. Nat Immunol 2001;2:1183-1188.
-
(2001)
Nat Immunol
, vol.2
, pp. 1183-1188
-
-
Schaeffer, E.M.1
-
67
-
-
0035221568
-
Akt provides the CD28 costimulatory signal for up-regulation of IL-2 and IFN-gamma but not TH2 cytokines
-
Kane LP, Andres PG, Howland KC, Abbas AK, Weiss A. Akt provides the CD28 costimulatory signal for up-regulation of IL-2 and IFN-gamma but not TH2 cytokines. Nat Immunol 2001;2:37-44.
-
(2001)
Nat Immunol
, vol.2
, pp. 37-44
-
-
Kane, L.P.1
Andres, P.G.2
Howland, K.C.3
Abbas, A.K.4
Weiss, A.5
-
68
-
-
0027220087
-
Identification of a novel signal transduction surface molecule on human cytotoxic lymphocytes
-
Valiante NM, Trinchieri G. Identification of a novel signal transduction surface molecule on human cytotoxic lymphocytes. J Exp Med 1993;178:1397-1406.
-
(1993)
J Exp Med
, vol.178
, pp. 1397-1406
-
-
Valiante, N.M.1
Trinchieri, G.2
-
69
-
-
0035576393
-
The activatory receptor 2B4 is expressed in vivo by human CD8+ effector alphabeta T cells
-
Speiser DE, et al. The activatory receptor 2B4 is expressed in vivo by human CD8+ effector alphabeta T cells. J Immunol 2001;167:6165-6170.
-
(2001)
J Immunol
, vol.167
, pp. 6165-6170
-
-
Speiser, D.E.1
-
70
-
-
0027244760
-
A novel function-associated molecule related to non-MHC-restricted cytotoxicity mediated by activated natural killer cells and T cells
-
Garni-Wagner BA, Purohit A, Mathew PA, Bennett M, Kumar V. A novel function-associated molecule related to non-MHC-restricted cytotoxicity mediated by activated natural killer cells and T cells. J Immunol 1993;151:60-70.
-
(1993)
J Immunol
, vol.151
, pp. 60-70
-
-
Garni-Wagner, B.A.1
Purohit, A.2
Mathew, P.A.3
Bennett, M.4
Kumar, V.5
-
71
-
-
0035059950
-
Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis
-
Moretta A, et al. Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis. Annu Rev Immunol 2001;19:197-223.
-
(2001)
Annu Rev Immunol
, vol.19
, pp. 197-223
-
-
Moretta, A.1
-
72
-
-
0034292341
-
NK cell inhibitory receptors prevent tyrosine phosphorylation of the activation receptor 2B4 (CD244)
-
Watzl C, Stebbins CC, Long EO. NK cell inhibitory receptors prevent tyrosine phosphorylation of the activation receptor 2B4 (CD244). J Immunol 2000;165:3545-3548.
-
(2000)
J Immunol
, vol.165
, pp. 3545-3548
-
-
Watzl, C.1
Stebbins, C.C.2
Long, E.O.3
-
73
-
-
0037066785
-
Association of the X-linked lymphoproliferative disease gene product SAP/SH2D1A with 2B4, a natural killer cell-activating molecule, is dependent on phosphoinositide 3-kinase
-
Aoukaty A, Tan R. Association of the X-linked lymphoproliferative disease gene product SAP/SH2D1A with 2B4, a natural killer cell-activating molecule, is dependent on phosphoinositide 3-kinase. J Biol Chem 2002;277:13331-13337.
-
(2002)
J Biol Chem
, vol.277
, pp. 13331-13337
-
-
Aoukaty, A.1
Tan, R.2
-
74
-
-
0036644060
-
2B4 is constitutively associated with linker for the activation of T cells in glycolipid-enriched microdomains: Properties required for 2B4 lytic function
-
Klem J, Verrett PC, Kumar V, Schatzle JD. 2B4 is constitutively associated with linker for the activation of T cells in glycolipid-enriched microdomains: properties required for 2B4 lytic function. J Immunol 2002;169:55-62.
-
(2002)
J Immunol
, vol.169
, pp. 55-62
-
-
Klem, J.1
Verrett, P.C.2
Kumar, V.3
Schatzle, J.D.4
-
75
-
-
0035575998
-
2B4 (CD244)-mediated activation of cytotoxicity and IFN-gamma release in human NK cells involves distinct pathways
-
Chuang SS, Kumaresan PR, Mathew PA. 2B4 (CD244)-mediated activation of cytotoxicity and IFN-gamma release in human NK cells involves distinct pathways. J Immunol 2001;167:6210-6216.
-
(2001)
J Immunol
, vol.167
, pp. 6210-6216
-
-
Chuang, S.S.1
Kumaresan, P.R.2
Mathew, P.A.3
-
76
-
-
0034528476
-
Analysis of the molecular mechanism involved in 2B4-mediated NK cell activation: Evidence that human 2B4 is physically and functionally associated with the linker for activation of T cells
-
Bottino C, et al. Analysis of the molecular mechanism involved in 2B4-mediated NK cell activation: evidence that human 2B4 is physically and functionally associated with the linker for activation of T cells. Eur J Immunol 2000;30:3718-3722.
-
(2000)
Eur J Immunol
, vol.30
, pp. 3718-3722
-
-
Bottino, C.1
-
77
-
-
0034294836
-
Defective NK cell activation in X-linked lymphoproliferative disease
-
Benoit L, Wang X, Pabst HF, Dutz J, Tan R. Defective NK cell activation in X-linked lymphoproliferative disease. J Immunol 2000;165:3549-3553.
-
(2000)
J Immunol
, vol.165
, pp. 3549-3553
-
-
Benoit, L.1
Wang, X.2
Pabst, H.F.3
Dutz, J.4
Tan, R.5
-
78
-
-
0037007090
-
Early expression of triggering receptors and regulatory role of 2B4 in human natural killer cell precursors undergoing in vitro differentiation
-
Sivori S, et al. Early expression of triggering receptors and regulatory role of 2B4 in human natural killer cell precursors undergoing in vitro differentiation. Proc Natl Acad Sci USA 2002;99:4526-4531.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 4526-4531
-
-
Sivori, S.1
-
79
-
-
0035892880
-
Cutting edge: Regulation of CD8(+) T cell proliferation by 2B4/CD48 interactions
-
Kambayashi T, Assarsson E, Chambers BJ, Ljunggren HG. Cutting edge: regulation of CD8(+) T cell proliferation by 2B4/CD48 interactions. J Immunol 2001;167:6706-6710.
-
(2001)
J Immunol
, vol.167
, pp. 6706-6710
-
-
Kambayashi, T.1
Assarsson, E.2
Chambers, B.J.3
Ljunggren, H.G.4
-
80
-
-
0034432939
-
Ly108: A new member of the mouse CD2 family of cell surface proteins
-
Peck SR, Ruley HE. Ly108: a new member of the mouse CD2 family of cell surface proteins. Immunogenetics 2000;52:63-72.
-
(2000)
Immunogenetics
, vol.52
, pp. 63-72
-
-
Peck, S.R.1
Ruley, H.E.2
-
81
-
-
0036080366
-
CD84 is up-regulated on a major population of human memory B cells and recruits the SH2 domain containing proteins SAP and EAT-2
-
Tangye SG, van de Weerdt BC, Avery DT, Hodgkin PD. CD84 is up-regulated on a major population of human memory B cells and recruits the SH2 domain containing proteins SAP and EAT-2. Eur J Immunol 2002;32:1640-1649.
-
(2002)
Eur J Immunol
, vol.32
, pp. 1640-1649
-
-
Tangye, S.G.1
Van De Weerdt, B.C.2
Avery, D.T.3
Hodgkin, P.D.4
|