Cutting edge: NK cell inhibitory receptors prevent tyrosine phosphorytlation of the activation receptor 2B4 (CD244)1

Journal of Immunology

Volumn 165, Issue 7, 2000, Pages 3545-3548

  Watzl, C ^a   Stebbins, C C ^a   Long, E O ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD94 ANTIGEN; CELL RECEPTOR; GAMMA INTERFERON; MAJOR HISTOCOMPATIBILITY ANTIGEN; NATURAL KILLER CELL ACTIVATION RECEPTOR 2B4; NATURAL KILLER CELL ACTIVATION RECEPTOR 2DL1; NATURAL KILLER CELL ACTIVATION RECEPTOR NKG2; TYROSINE; UNCLASSIFIED DRUG; CD244 PROTEIN, HUMAN; IMMUNOGLOBULIN RECEPTOR; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR; KILLER CELL IMMUNOGLOBULIN-LIKE RECEPTOR; KLRD1 PROTEIN, HUMAN; LECTIN; LEUKOCYTE ANTIGEN; MEMBRANE PROTEIN; NATURAL KILLER CELL ACTIVATING RECEPTORS;

ARTICLE; CELL ACTIVATION; CELL INTERACTION; CONTROLLED STUDY; CROSS LINKING; CYTOKINE RELEASE; CYTOLYSIS; HUMAN; HUMAN CELL; NATURAL KILLER CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TARGET CELL; CELL COMMUNICATION; CYTOTOXICITY; CYTOTOXICITY TEST; DRUG ANTAGONISM; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY;

ANTIGENS, CD; ANTIGENS, CD94; CELL COMMUNICATION; CYTOTOXICITY TESTS, IMMUNOLOGIC; CYTOTOXICITY, IMMUNOLOGIC; HUMANS; KILLER CELLS, NATURAL; LECTINS, C-TYPE; LYMPHOCYTE ACTIVATION; MEMBRANE GLYCOPROTEINS; PHOSPHORYLATION; RECEPTORS, IMMUNOLOGIC; TYROSINE;

EID: 0034292341     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.165.7.3545     Document Type: Article

References (31)

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5. SLP-76 is a direct substrate of SHP-1 recruited to killer cell inhibitory receptors
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14. Identification of the 2B4 molecule as a counter-receptor for CD48
15. 2B4, the natural killer and T cell immunoglobulin superfamily surface protein, is a ligand for CD48
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23. Cutting edge: Human 2B4, an activating NK cell receptor, recruits the protein tyrosine phosphatase SHP-2 and the adaptor signaling protein SAP
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